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Affinity Biochemical interaction (Binding assay) EUB0000138c PTK2B
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Affinity Biochemical interaction (Binding assay) EUB0000138c PTK2
Inhibition of FAK (unknown origin) using Fluorescein-Poly GAT as substrate incubated for 30 mins and measured after 60 mins by Lanthascreen assay
Assay data:38 Active, 1 Activity ≤ 1 nM, 48 Activity ≤ 1 µM, 49 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
In Vitro Activity Assay from US Patent US10450297: "Sulfonyl amide derivatives for the treatment of abnormal cell growth"
Assay data:327 Active, 145 Activity ≤ 1 nM, 328 Activity ≤ 1 µM, 328 Tested
Binding assay (PTK2B)
Assay data:1 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested
Binding assay (PTK2)
Inhibition of recombinant FAK (unknown origin) by radiometric kinase assay
Assay data:41 Active, 1 Activity ≤ 1 nM, 38 Activity ≤ 1 µM, 42 Tested
Inhibition of human Focal adhesion kinase
Inhibition of FAK (unknown origin)
Assay data:3 Active, 2 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Inhibition of human recombinant FAK
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry.
Assay data:21 Active, 2 Activity ≤ 1 nM, 18 Activity ≤ 1 µM, 243 Tested
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