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Cytotoxicity activity against human HepG2 cells assessed by CellTiter-Glo luminescent cell viability assay.
Assay data:1241 Active, 184 Activity ≤ 1 µM, 1545 Tested
Summary
Human kisspeptin (KISS1R) small molecule agonists, calcium flux assay in KISS1R-HEK293 cells: Summary
Assay data:16 Active, 9667 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same Project
Human gonadotropin-releasing hormone receptor (GnRHR) small molecule agonists, calcium flux assay in GnRHR-HEK293 cells: Summary
Assay data:109 Active, 9667 Tested
G protein-coupled receptor (GPCR) small molecule agonists, calcium flux assay: HEK293 wild type cell line counter screen
Assay data:47 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same Project
Human kisspeptin (KISS1R) small molecule agonists, calcium flux assay in KISS1R-HEK293 cells
Assay data:55 Active, 2 Activity ≤ 1 nM, 10 Activity ≤ 1 µM, 9667 Tested
Human gonadotropin-releasing hormone receptor (GnRHR) small molecule agonists, calcium flux assay in GnRHR-HEK293 cells
Assay data:169 Active, 2 Activity ≤ 1 nM, 27 Activity ≤ 1 µM, 9667 Tested
Nuclear factor erythroid 2-related factor 2/antioxidant responsive element (Nrf2/ARE) small molecule agonists: luciferase reporter gene qHTS assay in human keratinocytes
Assay data:1099 Active, 1 Activity ≤ 1 nM, 143 Activity ≤ 1 µM, 9667 Tested
Increase the activity of the Burkholderia fixLJ 2-component system
Assay data:87 Active, 28704 Tested
SummaryCompounds, ActivePubMed Citation
Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Assay data:281 Active, 189401 Tested
SummaryCompounds, Active
Primary qHTS Assay for Inhibitors of Recombinant Selenoprotein Glutathione Peroxidase 1 (GPX1)
Assay data:186 Active, 9 Activity ≤ 1 µM, 11353 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
NCATS anti-infectives library activity on HEK293 viability as a counter-qHTS vs the C. elegans viability qHTS
Assay data:25 Active, 678 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Depositor
Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: luciferase reporter qHTS assay
Assay data:2934 Active, 132 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Assay data:237 Active, 1947 Activity ≤ 1 µM, 141380 Tested
GF-AFC viability counterscreen for inhibitors of alpha-synuclein gene (SNCA) expression
Assay data:177 Active, 2 Activity ≤ 1 nM, 481 Activity ≤ 1 µM, 146379 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Depositor
Primary qHTS assay for inhibitors of human arachidonate 12S-lipoxygenase (ALOX12): Round 2
Assay data:6069 Active, 5332 Activity ≤ 1 µM, 575118 Tested
Primary qHTS assay for inhibitors of Glutamate pyruvate transaminase 2 (GPT2)
Assay data:249 Active, 449 Activity ≤ 1 µM, 100803 Tested
Primary qHTS for Inhibitors of N-terminal methyltransferase 1 (NTMT1): MTaseGlo Assay
Assay data:1477 Active, 244 Activity ≤ 1 µM, 58936 Tested
Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (IP6K1)
Assay data:1159 Active, 143951 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mitochondria
Assay data:128 Active, 5056 Tested
Primary qHTS for Identification of Small Molecule Activators of Huntingtin-Antisense Promoter Activity
Assay data:117 Active, 379 Activity ≤ 1 µM, 48411 Tested
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