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Primary qHTS Assay for Inhibitors of Recombinant Selenoprotein Glutathione Peroxidase 4 (GPX4)
Assay data:258 Active, 16 Activity ≤ 1 µM, 11046 Tested
SummaryRelated BioAssays by Target
Primary qHTS Assay for Inhibitors of Recombinant Selenoprotein Glutathione Peroxidase 1 (GPX1)
Assay data:186 Active, 9 Activity ≤ 1 µM, 11353 Tested
Primary qHTS for Inhibitors of N-terminal methyltransferase 1 (NTMT1): MTaseGlo Assay
Assay data:1477 Active, 244 Activity ≤ 1 µM, 58936 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Primary qHTS to identify inhibitors of SARS-CoV-2 cell entry
Assay data:368 Active, 78 Activity ≤ 1 µM, 5114 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Depositor
Cytotoxicity counterscreen for inhibitors of SARS-CoV-2 cell entry
Assay data:158 Active, 29 Activity ≤ 1 µM, 5114 Tested
Neuroprotective activity against amyloid beta (1 to 42) peptide-induced cytotoxicty in CD1 mouse primary cortical neurons assessed as increase in cell viability at 0.1 to 10 uM pre-incubated for 1 hr before amyloid beta (1 to 42) addition and measured after 24 hrs by CCK8 assay
Assay data:2 Active, 3 Tested
SummaryCompounds, ActivePubMed Citation
qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: tertiary screen by RT-qPCR
Assay data:34 Active, 24 Activity ≤ 1 µM, 62 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: Secondary screen by immunofluorescence
Assay data:150 Active, 107 Activity ≤ 1 µM, 216 Tested
qHTS assay to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: Counter screen cell viability and HiBit confirmation
Assay data:347 Active, 1 Activity ≤ 1 nM, 215 Activity ≤ 1 µM, 650 Tested
HIV1_TAR : FRET assay measuring displacement of FAM and TAMRA-labeled Tat peptide from HIV-1 TAR RNA.
Assay data:618 Active, 103146 Tested
SummaryCompounds, Active
Screen for inhibitors of RMI FANCM (MM2) intereaction
Assay data:402 Active, 69901 Tested
The chemical genetic matrix (CGM) dataset as reported in Wildenhain et al. (2015) Prediction of Synergism from Chemical-Genetic Interactions by Machine Learning. Cell Systems Volume 1, Issue 6, p383-395
Assay data:2021 Active, 5518 Tested
SummaryCompounds, ActiveRelated BioAssays by Same Project
Human Phosphogluconate dehydrogenase (6PGD) Inhibitor Screening
Assay data:15 Active, 2000 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
NCI In Vivo Anticancer Drug Screen. Data for tumor model L1210 Leukemia (intraperitoneal) in B6D2F1 (BDF1) mice
Assay data:1655 Active, 58883 Tested
NCI human tumor cell line growth inhibition assay. Data for the CAKI-1 Renal cell line
Assay data:3433 Active, 51871 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Depositor
NCI human tumor cell line growth inhibition assay. Data for the SW-620 Colon cell line
Assay data:4218 Active, 55343 Tested
NCI human tumor cell line growth inhibition assay. Data for the KM12 Colon cell line
Assay data:3660 Active, 54910 Tested
NCI human tumor cell line growth inhibition assay. Data for the SNB-19 Central Nervous System cell line
Assay data:2648 Active, 54600 Tested
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