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Inhibition of FGF1/FGFR2 D2 domain interaction in human MCF7 cells assessed as decrease in cell count at 0.1 to 1 uM by WST-1 assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to recombinant FGF1 (unknown origin) transformed in Escherichia coli BL21(DE3) pLysS cells assessed as dissociation constant by fluorescence spectrophotometry based Stern-Volmer method
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of FGF1/FGFR2 D2 domain interaction in human MCF7 cells assessed as decrease in cell proliferation at 0.1 to 1 uM by WST-1 assay
Assay data:2 Active, 2 Tested
Binding affinity to FGF-1 (unknown origin) at 800 nM by SPR assay
Assay data:6 Tested
Inhibition of FGF (unknown origin) at 10 uM after 120 mins P33 radiolabeled kinase activity assay
Assay data:3 Tested
Binding affinity to human recombinant FGF1 by surface plasmon resonance assay
Assay data:1 Active, 3 Tested
Binding affinity to human FGF1 (amino acid residues M1 to D141) at 0.125 to 2 uM by surface plasmon resonance assay
SummaryRelated BioAssays by Target
Binding affinity to FGF1 by surface plasmon resonance-based solution affinity assay
Assay data:24 Tested
Binding affinity to FGF-1 by surface plasmon resonance assay
Assay data:20 Active, 3 Activity ≤ 1 nM, 19 Activity ≤ 1 µM, 20 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity to FGF1 by surface plasmon-based solution affinity assay
Assay data:17 Active, 15 Activity ≤ 1 µM, 17 Tested
Binding affinity at FGF1
Assay data:1 Active, 1 Activity ≤ 1 µM, 7 Tested
Binding affinity for FGF1 by BIAcore solution affinity assay
Assay data:4 Active, 4 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 12 Tested
Binding affinity for Fibroblast growth factor 1
Assay data:20 Tested
Dissociation constant for Fibroblast growth factor 1
Assay data:6 Active, 4 Activity ≤ 1 µM, 20 Tested
Binding affinity for human fibroblast growth factor 1 in surface plasmon resonance (SPR) assay
Assay data:3 Active, 12 Tested
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