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Compound was evaluated for the cytotoxicity to L1210 leukemia cells in culture at ~1.6-fold higher concentrations and expressed as ID50
Assay data:2 Active, 2 Tested
SummaryCompounds, ActivePubMed Citation
Chemotherapeutic activity was evaluated by measuring mean tumor diameter on day 8 at 66 mg/kg/day, sc
Assay data:4 Tested
SummaryPubMed Citation
Chemotherapeutic activity was evaluated by measuring mean tumor diameter on day 8 at 60 mg/kg/day, sc
Assay data:5 Tested
Chemotherapeutic activity was evaluated by measuring mean tumor diameter on day 8 at 53 mg/kg/day, sc
Assay data:3 Tested
Chemotherapeutic activity was evaluated by measuring mean tumor diameter on day 8 at 48 mg/kg/day, sc
Assay data:1 Tested
Chemotherapeutic activity was evaluated by measuring mean tumor diameter on day 8 at 44 mg/kg/day, sc
Assay data:2 Tested
Chemotherapeutic activity was evaluated by measuring mean tumor diameter on day 8 at 12(mg/kg)/day, sc
Chemotherapeutic activity was evaluated by measuring mean tumor diameter on day 8 at 11 mg/kg/day, sc
Chemotherapeutic activity was evaluated by measuring mean tumor diameter on day 8 at 10 mg/kg/day, sc
Chemotherapeutic activity was evaluated by measuring mean tumor diameter on day 12 at 66 mg/kg/day, sc
Chemotherapeutic activity was evaluated by measuring mean tumor diameter on day 12 at 60 mg/kg/day, sc
Chemotherapeutic activity was evaluated by measuring mean tumor diameter on day 12 at 53 mg/kg/day, sc
Chemotherapeutic activity was evaluated by measuring mean tumor diameter on day 12 at 48 mg/kg/day, sc
Chemotherapeutic activity was evaluated by measuring mean tumor diameter on day 12 at 44 mg/kg/day, sc
Chemotherapeutic activity was evaluated by measuring mean tumor diameter on day 12 at 12(mg/kg)/day, sc
Chemotherapeutic activity was evaluated by measuring mean tumor diameter on day 12 at 11 mg/kg/day, sc
Chemotherapeutic activity was evaluated by measuring mean tumor diameter on day 12 at 10 mg/kg/day, sc
The agonist potency was assessed by measuring the inhibition of contraction at a single concentration (200 nM).
Assay data:2 Active, 2 Activity ≤ 1 µM, 7 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
The agonist potency was assessed by measuring the inhibition of contraction at a single concentration (200 nM)
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
In vivo blood glucose level in male db/db mice after administration of 3 mg/kg peroral dose of compound once in a day
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