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Inhibition of fungal HDAC using Boc-Lys (acetyl)-AMC as substrate preincubated for 12 hrs followed by substrate addition and measured after 6 hrs by fluorescence-based analysis
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Inhibition of fungal HSP90 incubated for 6 hrs in presence of FITC-Geldanamycin by fluorescence polarization analysis
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Antibacterial activity against fungi incubated for 18 hrs by CLSI based broth dilution method
Assay data:5 Active, 25 Tested
SummaryCompounds, ActivePubMed Citation
Inhibition of fungi 1,3-beta-D-glucan synthase
Assay data:4 Active, 4 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested
Inhibition of fungi maltase
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of fungal Lanosterol 14-alpha demethylase
Assay data:2 Tested
SummaryPubMed Citation
Inhibition of recombinant fungi CK1 (2 to 298 residues) assessed as residual activity at 10 uM using KRRRALS(p)VASLPGL as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control
Assay data:1 Tested
Inhibition of fungal keratinase activity at 10 mg/ml relative to control
Inhibition of fungal keratinase activity at 0.1 to 10 mg/ml relative to control
Inhibition of fungal AzgA expressed in Aspergillus nidulans assessed as reduction in AzgA-mediated [2,8-3H]-adenine accumulation
Inhibition of fungal FcyB expressed in Aspergillus nidulans assessed as reduction in FcyB-mediated [2,8-3H]-adenine accumulation
Assay data:2 Active, 12 Tested
Inhibition of fungal FcyB expressed in Aspergillus nidulans assessed as FcyB-mediated [2,8-3H]-adenine accumulation rate at 500 uM relative to untreated control
Assay data:6 Tested
Inhibition of fungal FcyB expressed in Aspergillus nidulans assessed as reduction in FcyB-mediated at 0.5 mM
Assay data:7 Tested
Inhibition of fungal UapA expressed in Aspergillus nidulans assessed as reduction in UapA-mediated [8-3H]-xanthine accumulation at 0.5 mM
Assay data:20 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of fungal AzgA expressed in Aspergillus nidulans assessed as reduction in AzgA-mediated [2,8-3H]-adenine accumulation at 0.5 mM
Assay data:4 Active, 4 Tested
Stability of the compound assessed as fungal protease type 2-mediated amide linkage cleavage at pH 7.6 after 24 hrs by paper electrophoretic analysis
Assay data:2 Active, 2 Tested
Inhibitory concentration against Dictyostelium discoideum cell growth
Assay data:12 Active, 18 Tested
Minimum inhibitory concentration to inhibit 90% of the isolates
Assay data:14 Tested
Minimum inhibitory concentration to inhibit 50% of the isolates
Assay data:13 Tested
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