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Inhibition of Manduca sexta V-type proton ATPase assessed as reduction in inorganic phosphate production pre-inucubated for 5 mins before Tris-ATP addition and measured after 2 mins
Assay data:8 Active, 8 Activity ≤ 1 µM, 8 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Growth inhibition of neonate larvae of Manduca sexta at 250 mg/l after 6 days relative to control
Assay data:25 Tested
SummaryPubMed Citation
Antifeedant activity against Manduca sexta at 100 ug/ml after 6 days
Assay data:3 Tested
Inhibition of tobacco hornworm V-ATPase c subunit
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity to tobacco hornworm V-ATPase c subunit in 4:4:1 CDCl3:MeOH-d4:D2O by NMR analysis
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Manduca sexta V-ATPase V1/Vo holoenzyme activity assessed as inorganic phosphate production pretreated for 5 mins
Assay data:6 Tested
Antifeedant activity in Manduca sexta by choice test
Assay data:1 Tested
Summary
Inhibition of Manduca sexta juvenile hormone esterase F2591 mutant
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
Inhibition of Manduca sexta juvenile hormone esterase
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of tobacco hornworm V-ATPase
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of tobacco hornworm midgut vacuolar ATPase V1/V0 holoenzyme
Assay data:5 Active, 1 Activity ≤ 1 nM, 5 Activity ≤ 1 µM, 5 Tested
Drug level in Photorhabdus luminescens TT01 infected Manduca sexta hemolymph after 24 hrs by TLC plate method
Inhibition of immune system assessed as suppression of melanotic nodule formation in Photorhabdus luminescens TT01 infected Manduca sexta
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
Inhibition of Manduca sexta phenoloxidase at 60 uM
Inhibitory effect on outgrowth of MRRL-CH1 cell line at 5 uM concentration; No Effect
Inhibitory effect on outgrowth of MRRL-CH1 cell line at 5 uM concentration; Irreversible
Inhibitory effect on outgrowth of MRRL-CH1 cell line at 1 uM concentration; No Effect
Inhibitory effect on outgrowth of MRRL-CH1 cell line at 1 uM concentration; Irreversible
Inhibitory effect on outgrowth of MRRL-CH1 cell line at 0.5 uM concentration; Reversible
Inhibitory effect on outgrowth of MRRL-CH1 cell line at 0.5 uM concentration; No Effect
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