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Inhibitory activity against avian c-Src tyrosine kinase was determined.
Assay data:40 Active, 37 Activity ≤ 1 µM, 47 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of the phosphorylation of a random glutamate-tyrosine (4:1) copolymer by isolated avian c-Src protein.
Assay data:10 Active, 6 Activity ≤ 1 µM, 21 Tested
Relative yield of the product (4b) derived from the compound with DMAPP in the enzymatic reaction catalyzed by FPP synthase from avian liver
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Relative yield of the product (4b') derived from the compound with GPP in the enzymatic reaction catalyzed by FPP synthase from avian liver
Relative yield of the product (3b) derived from the compound with DMAPP in the enzymatic reaction catalyzed by FPP synthase from avian liver
Kobs versus inhibitory concentration
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Inhibition of Avian AIR carboxylase in presence of 0.5 nM of the compound
Changes in free energy concentration
Relative yield of the product (FPP) derived from the compound with GPP in the enzymatic reaction catalyzed by FPP synthase from avian liver
SummaryPubMed Citation
Relative yield of the product (FPP) derived from the compound with DMAPP in the enzymatic reaction catalyzed by FPP synthase from avian liver
Relative yield of the product (4d) derived from the compound with DMAPP in the enzymatic reaction catalyzed by FPP synthase from avian liver; ND = Not detected
Relative yield of the product (4c) derived from the compound with GPP in the enzymatic reaction catalyzed by FPP synthase from avian liver; ND = Not detected
Relative yield of the product (3c) derived from the compound with DMAPP in the enzymatic reaction catalyzed by FPP synthase from avian liver
Relative yield of the product (3b) derived from the compound with DMAPP in the enzymatic reaction catalyzed by FPP synthase from avian liver; ND = Not detected
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