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Select item 104877751.

NLRC5 Deficiency Reduces LPS-Induced Microglial Activation via Inhibition of NF-κB Signaling and Ameliorates Mice’s Depressive-like Behavior

Chen Sun, Yuqing Shen, Piaopiao Liu, Yi Shen, Yue Hu, Ping Li, Ying Zhang, Fengqin Miao, Jianqiong Zhang

Int J Mol Sci. 2023 Sep; 24(17): 13265. Published online 2023 Aug 26. doi: 10.3390/ijms241713265

PMCID:: PMC10487775

Article PDF–4.1M

Select item 101117532.

NOD-like receptor NLRC5 promotes neuroinflammation and inhibits neuronal survival in Parkinson’s disease models

Zhaolin Liu, Chenye Shen, Heng Li, Jiabin Tong, Yufei Wu, Yuanyuan Ma, Jinghui Wang, Zishan Wang, Qing Li, Xiaoshuang Zhang, Hongtian Dong, Yufang Yang, Mei Yu, Jian Wang, Renyuan Zhou, Jian Fei, Fang Huang

J Neuroinflammation. 2023; 20: 96. Published online 2023 Apr 18. doi: 10.1186/s12974-023-02755-4

PMCID:: PMC10111753

Article PDF–11M

Select item 100344703.

NLRC5 affects diet-induced adiposity in female mice and co-regulates peroxisome proliferator-activated receptor PPARγ target genes

Sarah Bauer, Vanessa Aeissen, Alena M. Bubeck, Ioannis Kienes, Kornelia Ellwanger, Mona Scheurenbrand, Fjolla Rexhepi, Sheela Ramanathan, Philip Rosenstiel, W. Florian Fricke, Thomas A. Kufer

iScience. 2023 Apr 21; 26(4): 106313. Published online 2023 Mar 2. doi: 10.1016/j.isci.2023.106313

PMCID:: PMC10034470

Article PDF–4.0M

Select item 85462064.

NLRC5 Deficiency Deregulates Hepatic Inflammatory Response but Does Not Aggravate Carbon Tetrachloride-Induced Liver Fibrosis

Akouavi Julite I. Quenum, Akhil Shukla, Fjolla Rexhepi, Maryse Cloutier, Amit Ghosh, Thomas A. Kufer, Sheela Ramanathan, Subburaj Ilangumaran

Front Immunol. 2021; 12: 749646. Published online 2021 Oct 12. doi: 10.3389/fimmu.2021.749646

PMCID:: PMC8546206

Article PDF–7.0M

Select item 77531385.

NLRC5 promotes transcription of BTN3A1-3 genes and Vγ9Vδ2 T cell-mediated killing

Anh Thu Dang, Juliane Strietz, Alessandro Zenobi, Hanif J. Khameneh, Simon M. Brandl, Laura Lozza, Gregor Conradt, Stefan H.E. Kaufmann, Walter Reith, Ivo Kwee, Susana Minguet, Sonia T. Chelbi, Greta Guarda

iScience. 2021 Jan 22; 24(1): 101900. Published online 2020 Dec 7. doi: 10.1016/j.isci.2020.101900

PMCID:: PMC7753138

Article PDF–3.6M

Select item 65990276.

NLRC5 inhibits neointima formation following vascular injury and directly interacts with PPARγ

Peipei Luan, Weixia Jian, Xu Xu, Wenxin Kou, Qing Yu, Handan Hu, Dali Li, Wei Wang, Mark W. Feinberg, Jianhui Zhuang, Yawei Xu, Wenhui Peng

Nat Commun. 2019; 10: 2882. Published online 2019 Jun 28. doi: 10.1038/s41467-019-10784-y

PMCID:: PMC6599027

Article PDF–4.0M

Select item 55531857.

Deficiency of the NOD-Like Receptor NLRC5 Results in Decreased CD8⁺ T Cell Function and Impaired Viral Clearance

Christopher R. Lupfer, Kate L. Stokes, Teneema Kuriakose, Thirumala-Devi Kanneganti

J Virol. 2017 Sep 1; 91(17): e00377-17. Prepublished online 2017 Jun 14. Published online 2017 Aug 10. doi: 10.1128/JVI.00377-17

PMCID:: PMC5553185

Article PDF–3.9M

Select item 33461588.

NLRC5 regulates MHC class I antigen presentation in host defense against intracellular pathogens

Yikun Yao, Yalong Wang, Fuxiang Chen, Yin Huang, Shu Zhu, Qibin Leng, Hongyan Wang, Yufang Shi, Youcun Qian

Cell Res. 2012 May; 22(5): 836–847. Published online 2012 Apr 10. doi: 10.1038/cr.2012.56

PMCID:: PMC3346158

Article PDF–1.2M

Select item 33436629.

Enhanced TLR-induced NF-κB signaling and type I interferon responses in NLRC5 deficient mice

Yanzheng Tong, Jun Cui, Qingtian Li, Jia Zou, Helen Y Wang, Rong-Fu Wang

Cell Res. 2012 May; 22(5): 822–835. Published online 2012 Apr 3. doi: 10.1038/cr.2012.53

PMCID:: PMC3343662

Article PDF–2.4M

Select item 332780210.

Molecular cloning of large alternative transcripts based on comparative phylogenetic analysis and exploration of an EST database

Jiabing Ji, Rongfu Wang

Anal Biochem. Author manuscript; available in PMC 2013 May 15.

Published in final edited form as: Anal Biochem. 2012 May 15; 424(2): 140–141. Published online 2012 Mar 1. doi: 10.1016/j.ab.2012.02.030

PMCID:: PMC3327802

Article PDF–219K

Select item 724268711.

The USP14–NLRC5 pathway inhibits titanium particle–induced osteolysis in mice by suppressing NF-κB and PI3K/AKT activities

Guibin Fang, Yuan Fu, Shixun Li, Junxiong Qiu, Manyuan Kuang, Sipeng Lin, Changchuan Li, Yue Ding

J Biol Chem. 2020 May 15; 295(20): 7018–7032. Published online 2020 Apr 9. doi: 10.1074/jbc.RA119.012495

PMCID:: PMC7242687

Article PDF–5.2M

Select item 660381312.

Effect of NLRC5 on activation and reversion of hepatic stellate cells by regulating the nuclear factor-κB signaling pathway

Yan-Zhen Zhang, Jian-Ning Yao, Lian-Feng Zhang, Chun-Feng Wang, Xue-Xiu Zhang, Bing Gao

World J Gastroenterol. 2019 Jun 28; 25(24): 3044–3055. Published online 2019 Jun 28. doi: 10.3748/wjg.v25.i24.3044

PMCID:: PMC6603813

Article PDF–9.8M

Select item 568674913.

Novel Role for Interleukin-17 in Enhancing Type 1 Helper T Cell Immunity in the Female Genital Tract following Mucosal Herpes Simplex Virus 2 Vaccination

Puja Bagri, Varun C. Anipindi, Philip V. Nguyen, Danielle Vitali, Martin R. Stämpfli, Charu Kaushic

J Virol. 2017 Dec 1; 91(23): e01234-17. Prepublished online 2017 Sep 27. Published online 2017 Nov 14. doi: 10.1128/JVI.01234-17

PMCID:: PMC5686749

Article PDF–2.1M

Select item 357842614.

Cutting Edge: Impaired MHC Class I Expression in Mice Deficient for Nlrc5/CITA

Amlan Biswas, Torsten B. Meissner, Taro Kawai, Koichi S. Kobayashi

J Immunol. Author manuscript; available in PMC 2013 Jul 15.

Published in final edited form as: J Immunol. 2012 Jul 15; 189(2): 516–520. Published online 2012 Jun 18. doi: 10.4049/jimmunol.1200064

PMCID:: PMC3578426

Article PDF–741K

Select item 339785515.

Regulation of Class I Major Histocompatibility Complex (MHC) by Nucleotide-binding Domain, Leucine-rich Repeat-containing (NLR) Proteins

Gregory R. Robbins, Agnieszka D. Truax, Beckley K. Davis, Lu Zhang, W. June Brickey, Jenny P.-Y. Ting

J Biol Chem. 2012 Jul 13; 287(29): 24294–24303. Published online 2012 May 29. doi: 10.1074/jbc.M112.364604

PMCID:: PMC3397855

Article PDF–3.1M

Select item 719360116.

Transcriptional Upregulation of NLRC5 by Radiation Drives STING- and Interferon-Independent MHC-I Expression on Cancer Cells and T Cell Cytotoxicity

Lauren K. Zebertavage, Alejandro Alice, Marka R. Crittenden, Michael J. Gough

Sci Rep. 2020; 10: 7376. Published online 2020 Apr 30. doi: 10.1038/s41598-020-64408-3

PMCID:: PMC7193601

Article PDF–5.2M

Select item 666039817.

HIV-1 Tat-mediated microglial inflammation involves a novel miRNA-34a-NLRC5-NFκB signaling axis

Palsamy Periyasamy, Annadurai Thangaraj, Venkata Sunil Bendi, Shilpa Buch

Brain Behav Immun. Author manuscript; available in PMC 2020 Aug 1.

Published in final edited form as: Brain Behav Immun. 2019 Aug; 80: 227–237. Published online 2019 Mar 11. doi: 10.1016/j.bbi.2019.03.011

PMCID:: PMC6660398

Article PDF–1.9M

Select item 474998118.

NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions

Kristina Ludigs, Camilla Jandus, Daniel T. Utzschneider, Francesco Staehli, Stéphanie Bessoles, Anh Thu Dang, Giorgia Rota, Wilson Castro, Dietmar Zehn, Eric Vivier, Werner Held, Pedro Romero, Greta Guarda

Nat Commun. 2016; 7: 10554. Published online 2016 Feb 10. doi: 10.1038/ncomms10554

PMCID:: PMC4749981

Article PDF–863K

Select item 437474819.

NLRC5 Exclusively Transactivates MHC Class I and Related Genes through a Distinctive SXY Module

Kristina Ludigs, Queralt Seguín-Estévez, Sylvain Lemeille, Isabel Ferrero, Giorgia Rota, Sonia Chelbi, Chantal Mattmann, H. Robson MacDonald, Walter Reith, Greta Guarda

PLoS Genet. 2015 Mar; 11(3): e1005088. Published online 2015 Mar 26. doi: 10.1371/journal.pgen.1005088