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Items: 1 to 20 of 58

1.
Dependence of Transcription-Coupled DNA Supercoiling on Promoter Strength in Escherichia coli Topoisomerase I Deficient Strains
Xiaoduo Zhi, Fenfei Leng
Gene. Author manuscript; available in PMC 2018 Jun 8.
Published in final edited form as: Gene. 2013 Feb 10; 514(2): 82–90. Published online 2012 Nov 29. doi: 10.1016/j.gene.2012.11.011
PMCID:
PMC5992923
ArticlePDF–3.5M
2.
Structural basis for suppression of hypernegative DNA supercoiling by E. coli topoisomerase I
Kemin Tan, Qingxuan Zhou, Bokun Cheng, Zhongtao Zhang, Andrzej Joachimiak, Yuk-Ching Tse-Dinh
Nucleic Acids Res. 2015 Dec 15; 43(22): 11031–11046. Published online 2015 Oct 20. doi: 10.1093/nar/gkv1073
PMCID:
PMC4678816
ArticlePDF–13M
3.
Antimicrobial Susceptibility and SOS-Dependent Increase in Mutation Frequency Are Impacted by Escherichia coli Topoisomerase I C-Terminal Point Mutation
Jenny Yang, Thirunavukkarasu Annamalai, Bokun Cheng, Srikanth Banda, Rakhi Tyagi, Yuk-Ching Tse-Dinh
Antimicrob Agents Chemother. 2015 Oct; 59(10): 6195–6202. Prepublished online 2015 Jul 27. Published online 2015 Sep 18. doi: 10.1128/AAC.00855-15
PMCID:
PMC4576087
ArticlePDF–1.0M
4.
On the viability of Escherichia coli cells lacking DNA topoisomerase I
Anna Stockum, Robert G Lloyd, Christian J Rudolph
BMC Microbiol. 2012; 12: 26. Published online 2012 Feb 28. doi: 10.1186/1471-2180-12-26
PMCID:
PMC3313902
ArticlePDF–1.2M
5.
Asp to Asn substitution at the first position of the DxD TOPRIM motif of recombinant bacterial topoisomerase I is extremely lethal to E. coli
Bokun Cheng, Thirunavakkarasu Annamalai, Elena Sorokin, Maria Abrenica, Sandra Aedo, Yuk-Ching Tse-Dinh
J Mol Biol. Author manuscript; available in PMC 2010 Jul 19.
Published in final edited form as: J Mol Biol. 2009 Jan 16; 385(2): 558–567. Published online 2008 Nov 5. doi: 10.1016/j.jmb.2008.10.073
PMCID:
PMC2905861
ArticlePDF–1.7M
6.
Bacterial topoisomerase I as a target for discovery of antibacterial compounds
Yuk-Ching Tse-Dinh
Nucleic Acids Res. 2009 Feb; 37(3): 731–737. Published online 2008 Nov 28. doi: 10.1093/nar/gkn936
PMCID:
PMC2647297
ArticlePDF–1.0M
7.
Mutation adjacent to the active site tyrosine can enhance DNA cleavage and cell killing by the TOPRIM Gly to Ser mutant of bacterial topoisomerase I
Bokun Cheng, Elena P. Sorokin, Yuk-Ching Tse-Dinh
Nucleic Acids Res. 2008 Feb; 36(3): 1017–1025. Published online 2007 Dec 20. doi: 10.1093/nar/gkm1126
PMCID:
PMC2241903
ArticlePDF–1.0M
8.
Transcription-coupled Hypernegative Supercoiling of Plasmid DNA by T7 RNA Polymerase in Escherichia coli Topoisomerase I Deficient Strains
Rebecca Samul, Fenfei Leng
J Mol Biol. Author manuscript; available in PMC 2008 Dec 7.
Published in final edited form as: J Mol Biol. 2007 Dec 7; 374(4): 925–935. Published online 2007 Oct 11. doi: 10.1016/j.jmb.2007.10.011
PMCID:
PMC2151476
ArticlePDF–898K
9.
New peptide inhibitors of type IB topoisomerases: similarities and differences vis a vis inhibitors of tyrosine recombinases
David F. Fujimoto, Clemencia Pinilla, Anca M. Segall
J Mol Biol. Author manuscript; available in PMC 2007 May 24.
Published in final edited form as: J Mol Biol. 2006 Nov 10; 363(5): 891–907. Published online 2006 Aug 24. doi: 10.1016/j.jmb.2006.08.052
PMCID:
PMC1876744
ArticlePDF–960K
10.
Experimental and computational investigations of Ser10 and Lys13 in the binding and cleavage of DNA substrates by Escherichia coli DNA topoisomerase I
Daniel Strahs, Chang-Xi Zhu, Bokun Cheng, Jason Chen, Yuk-Ching Tse-Dinh
Nucleic Acids Res. 2006; 34(6): 1785–1797. Published online 2006 Mar 31. doi: 10.1093/nar/gkl109
PMCID:
PMC1421505
ArticlePDF–1.4M
11.
BACTERIAL CELL KILLING MEDIATED BY TOPOISOMERASE I DNA CLEAVAGE ACTIVITY
Bokun Cheng, Shikha Shukla, Sarinnapha Vasunilashorn, Somshuvra Mukhopadhyay, Yuk-Ching Tse-Dinh
J Biol Chem. Author manuscript; available in PMC 2006 Jan 26.
Published in final edited form as: J Biol Chem. 2005 Nov 18; 280(46): 38489–38495. Published online 2005 Sep 13. doi: 10.1074/jbc.M509722200
PMCID:
PMC1351368
ArticlePDF–821K
12.
Inhibition of Escherichia coli DNA topoisomerase I activity by phospholipids.
T Mizushima, S Natori, K Sekimizu
Biochem J. 1992 Jul 15; 285(Pt 2): 503–506. doi: 10.1042/bj2850503
PMCID:
PMC1132816
SummaryPage BrowsePDF–1.0M
13.
The Escherichia coli supX locus is topA, the structural gene for DNA topoisomerase I.
P Margolin, L Zumstein, R Sternglanz, J C Wang
Proc Natl Acad Sci U S A. 1985 Aug; 82(16): 5437–5441. doi: 10.1073/pnas.82.16.5437
PMCID:
PMC390584
SummaryPage BrowsePDF–1.3M
14.
Cloning of the gene topA encoding for DNA topoisomerase I and the physical mapping of the cysB-topA-trp region of Escherichia coli.
J C Wang, K Becherer
Nucleic Acids Res. 1983 Mar 25; 11(6): 1773–1790. doi: 10.1093/nar/11.6.1773
PMCID:
PMC325835
SummaryPage BrowsePDF–1.5M
15.
Mutations in the gene coding for Escherichia coli DNA topoisomerase I affect transcription and transposition.
R Sternglanz, S DiNardo, K A Voelkel, Y Nishimura, Y Hirota, K Becherer, L Zumstein, J C Wang
Proc Natl Acad Sci U S A. 1981 May; 78(5): 2747–2751. doi: 10.1073/pnas.78.5.2747
PMCID:
PMC319434
SummaryPage BrowsePDF–1.1M
16.
Identification and localization of a gene that specifies production of Escherichia coli DNA topoisomerase I.
M Trucksis, R E Depew
Proc Natl Acad Sci U S A. 1981 Apr; 78(4): 2164–2168. doi: 10.1073/pnas.78.4.2164
PMCID:
PMC319304
SummaryPage BrowsePDF–903K
17.
Escherichia coli and Salmonella typhimurium supX genes specify deoxyribonucleic acid topoisomerase I.
M Trucksis, E I Golub, D J Zabel, R E Depew
J Bacteriol. 1981 Aug; 147(2): 679–681. doi: 10.1128/jb.147.2.679-681.1981
PMCID:
PMC216090
SummaryPage BrowsePDF–439K
18.
Novobiocin-dependent topA deletion mutants of Escherichia coli.
G G Hammond, P J Cassidy, K M Overbye
J Bacteriol. 1991 Sep; 173(17): 5564–5567. doi: 10.1128/jb.173.17.5564-5567.1991
PMCID:
PMC208273
SummaryPage BrowsePDF–798K
19.
Anchoring of DNA to the bacterial cytoplasmic membrane through cotranscriptional synthesis of polypeptides encoding membrane proteins or proteins for export: a mechanism of plasmid hypernegative supercoiling in mutants deficient in DNA topoisomerase I.
A S Lynch, J C Wang
J Bacteriol. 1993 Mar; 175(6): 1645–1655. doi: 10.1128/jb.175.6.1645-1655.1993
PMCID:
PMC203958
SummaryPage BrowsePDF–2.9M
20.
The role of the Zn(II) binding domain in the mechanism of E. coli DNA topoisomerase I
Adriana Ahumada, Yuk-Ching Tse-Dinh
BMC Biochem. 2002; 3: 13. Published online 2002 May 29. doi: 10.1186/1471-2091-3-13
PMCID:
PMC115839
ArticlePDF–849K

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