PMC Links for GEO Profiles (Select 115112410) - PMC

Xiaoqing Xie, Pradeep Kumar Patnana, Daria Frank, Judith Schütte, Yahya Al-Matary, Axel Künstner, Hauke Busch, Helal Ahmed, Longlong Liu, Daniel R. Engel, Ulrich Dührsen, Frank Rosenbauer, Nikolas Von Bubnoff, Georg Lenz, Cyrus Khandanpour

Front Cell Dev Biol. 2023; 11: 866847. Published online 2023 Apr 5. doi: 10.3389/fcell.2023.866847

PMCID:: PMC10113925

Article PDF–2.3M

Select item 98033604.

Tbx2 is a master regulator of inner versus outer hair cell differentiation

Jaime García-Añoveros, John C. Clancy, Chuan Zhi Foo, Ignacio García-Gómez, Yingjie Zhou, Kazuaki Homma, Mary Ann Cheatham, Anne Duggan

Nature. Author manuscript; available in PMC 2022 Dec 30.

Published in final edited form as: Nature. 2022 May; 605(7909): 298–303. Published online 2022 May 4. doi: 10.1038/s41586-022-04668-3

PMCID:: PMC9803360

Article PDF–4.3M

Select item 97080775.

Cellular reprogramming with ATOH1, GFI1, and POU4F3 implicate epigenetic changes and cell-cell signaling as obstacles to hair cell regeneration in mature mammals

Amrita A Iyer, Ishwar Hosamani, John D Nguyen, Tiantian Cai, Sunita Singh, Melissa M McGovern, Lisa Beyer, Hongyuan Zhang, Hsin-I Jen, Rizwan Yousaf, Onur Birol, Jenny J Sun, Russell S Ray, Yehoash Raphael, Neil Segil, Andrew K Groves

eLife. 2022; 11: e79712. Published online 2022 Nov 29. doi: 10.7554/eLife.79712

PMCID:: PMC9708077

Article PDF–21M

Select item 95926046.

Function of bidirectional sensitivity in the otolith organs established by transcription factor Emx2

Young Rae Ji, Yosuke Tona, Talah Wafa, Matthew E. Christman, Edward D. Tourney, Tao Jiang, Sho Ohta, Hui Cheng, Tracy Fitzgerald, Bernd Fritzsch, Sherri M. Jones, Kathleen E. Cullen, Doris K. Wu

Nat Commun. 2022; 13: 6330. Published online 2022 Oct 24. doi: 10.1038/s41467-022-33819-3

PMCID:: PMC9592604

Article PDF–18M

Select item 91591097.

Murine AGM single-cell profiling identifies a continuum of hemogenic endothelium differentiation marked by ACE

Muhammad Zaki Hidayatullah Fadlullah, Wen Hao Neo, Michael Lie-a-ling, Roshana Thambyrajah, Rahima Patel, Renaud Mevel, Irène Aksoy, Nam Do Khoa, Pierre Savatier, Laura Fontenille, Syed Murtuza Baker, Magnus Rattray, Valerie Kouskoff, Georges Lacaud

Blood. 2022 Jan 20; 139(3): 343–356. doi: 10.1182/blood.2020007885

PMCID:: PMC9159109

Article

Select item 90984378.

GFI1 regulates hair cell differentiation by acting as an off-DNA transcriptional co-activator of ATOH1, and a DNA-binding repressor

Hsin-I Jen, Sunita Singh, Litao Tao, Helen R. Maunsell, Neil Segil, Andrew K. Groves

Sci Rep. 2022; 12: 7793. Published online 2022 May 12. doi: 10.1038/s41598-022-11931-0

PMCID:: PMC9098437

Article PDF–5.3M

Select item 87856859.

A Novel in vitro Model Delineating Hair Cell Regeneration and Neural Reinnervation in Adult Mouse Cochlea

Wenyan Li, Yizhou Quan, Mingqian Huang, Wei Wei, Yilai Shu, Huawei Li, Zheng-Yi Chen

Front Mol Neurosci. 2021; 14: 757831. Published online 2022 Jan 10. doi: 10.3389/fnmol.2021.757831

PMCID:: PMC8785685

Article PDF–7.7M

Select item 871592410.

Disruption of Hars2 in Cochlear Hair Cells Causes Progressive Mitochondrial Dysfunction and Hearing Loss in Mice

Pengcheng Xu, Longhao Wang, Hu Peng, Huihui Liu, Hongchao Liu, Qingyue Yuan, Yun Lin, Jun Xu, Xiuhong Pang, Hao Wu, Tao Yang

Front Cell Neurosci. 2021; 15: 804345. Published online 2021 Dec 15. doi: 10.3389/fncel.2021.804345

PMCID:: PMC8715924

Article PDF–17M

Select item 863999311.

GFI1 tethers the NuRD complex to open and transcriptionally active chromatin in myeloid progenitors

Anne Helness, Jennifer Fraszczak, Charles Joly-Beauparlant, Halil Bagci, Christian Trahan, Kaifee Arman, Peiman Shooshtarizadeh, Riyan Chen, Marina Ayoub, Jean-François Côté, Marlene Oeffinger, Arnaud Droit, Tarik Möröy

Commun Biol. 2021; 4: 1356. Published online 2021 Dec 2. doi: 10.1038/s42003-021-02889-2

Correction in:: Commun Biol. 2022; 5: 922.

PMCID:: PMC8639993

Article PDF–6.1M

Select item 861628312.

Gfi1 Loss Protects against Two Models of Induced Diabetes

Tiziana Napolitano, Fabio Avolio, Serena Silvano, Sara Forcisi, Anja Pfeifer, Andhira Vieira, Sergi Navarro-Sanz, Marika Elsa Friano, Chaïma Ayachi, Anna Garrido-Utrilla, Josipa Atlija, Biljana Hadzic, Jérôme Becam, Anette Sousa-De-Veiga, Magali Dodille Plaisant, Shruti Balaji, Didier F. Pisani, Magali Mondin, Philippe Schmitt-Kopplin, Ez-Zoubir Amri, Patrick Collombat

Cells. 2021 Nov; 10(11): 2805. Published online 2021 Oct 20. doi: 10.3390/cells10112805

PMCID:: PMC8616283

Article PDF–11M

Select item 860833013.

IFNγ suppresses the expression of GFI1 and thereby inhibits Th2 cell proliferation

Murshed H. Sarkar, Ryoji Yagi, Yukihiro Endo, Ryo Koyama-Nasu, Yangsong Wang, Ichita Hasegawa, Toshihiro Ito, Ilkka S. Junttila, Jinfang Zhu, Motoko Y. Kimura, Toshinori Nakayama

PLoS One. 2021; 16(11): e0260204. Published online 2021 Nov 22. doi: 10.1371/journal.pone.0260204

PMCID:: PMC8608330

Article PDF–1.7M

Select item 828595714.

RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signaling

Kaiwen W. Chen, Benjamin Demarco, Saray Ramos, Rosalie Heilig, Michiel Goris, James P. Grayczyk, Charles-Antoine Assenmacher, Enrico Radaelli, Leonel D. Joannas, Jorge Henao-Mejia, Fabienne Tacchini-Cottier, Igor E. Brodsky, Petr Broz

Proc Natl Acad Sci U S A. 2021 Jul 13; 118(28): e2101189118. Published online 2021 Jul 6. doi: 10.1073/pnas.2101189118

PMCID:: PMC8285957

Article PDF–1.8M

Select item 812914115.

EMX2-GPR156-Gαi reverses hair cell orientation in mechanosensory epithelia

Katie S. Kindt, Anil Akturk, Amandine Jarysta, Matthew Day, Alisha Beirl, Michaela Flonard, Basile Tarchini

Nat Commun. 2021; 12: 2861. Published online 2021 May 17. doi: 10.1038/s41467-021-22997-1

PMCID:: PMC8129141

Article PDF–12M

Select item 811582416.

C1ql1 is expressed in adult outer hair cells of the cochlea in a tonotopic gradient

Joyshree Biswas, Robert S. Pijewski, Rohit Makol, Tania G. Miramontes, Brianna L. Thompson, Lyndsay C. Kresic, Alice L. Burghard, Douglas L. Oliver, David C. Martinelli

PLoS One. 2021; 16(5): e0251412. Published online 2021 May 12. doi: 10.1371/journal.pone.0251412

PMCID:: PMC8115824

Article PDF–13M

Select item 804115417.

Mouse models of neutropenia reveal progenitor-stage-specific defects

David E. Muench, Andre Olsson, Kyle Ferchen, Giang Pham, Rachel A. Serafin, Somchai Chutipongtanate, Pankaj Dwivedi, Baobao Song, Stuart Hay, Kashish Chetal, Lisa R. Trump-Durbin, Jayati Mookerjee-Basu, Kejian Zhang, Jennifer C. Yu, Carolyn Lutzko, Kasiani C. Myers, Kristopher L. Nazor, Kenneth D. Greis, Dietmar J. Kappes, Sing Sing Way, Nathan Salomonis, H. Leighton Grimes

Nature. Author manuscript; available in PMC 2021 Apr 12.

Published in final edited form as: Nature. 2020 Jun; 582(7810): 109–114. Published online 2020 Apr 22. doi: 10.1038/s41586-020-2227-7

PMCID:: PMC8041154

Article PDF–8.0M

Select item 772273818.

Combinatorial Atoh1 and Gfi1 induction enhances hair cell regeneration in the adult cochlea

Sungsu Lee, Jae-Jun Song, Lisa A. Beyer, Donald L. Swiderski, Diane M. Prieskorn, Melih Acar, Hsin-I Jen, Andrew K. Groves, Yehoash Raphael

Sci Rep. 2020; 10: 21397. Published online 2020 Dec 8. doi: 10.1038/s41598-020-78167-8

PMCID:: PMC7722738

Article PDF–5.7M

Select item 753593319.

Live imaging of hair bundle polarity acquisition demonstrates a critical timeline for transcription factor Emx2

Yosuke Tona, Doris K Wu

eLife. 2020; 9: e59282. Published online 2020 Sep 23. doi: 10.7554/eLife.59282

PMCID:: PMC7535933

Article PDF–14M

Select item 750259520.

GFI1 functions to repress neuronal gene expression in the developing inner ear hair cells

Maggie S. Matern, Beatrice Milon, Erika L. Lipford, Mark McMurray, Yoko Ogawa, Andrew Tkaczuk, Yang Song, Ran Elkon, Ronna Hertzano

Development. 2020 Sep 1; 147(17): dev186015. Published online 2020 Sep 11. doi: 10.1242/dev.186015

PMCID:: PMC7502595

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