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Select item 97801771.

Neutrophil complement receptor signaling is required for BAFF-dependent humoral responses in mice

Arun Cumpelik, Evan Cody, Samuel Mon-Wei Yu, Emilie K. Grasset, David Dominguez-Sola, Andrea Cerutti, Peter S. Heeger

J Immunol. Author manuscript; available in PMC 2024 Jan 1.

Published in final edited form as: J Immunol. 2023 Jan 1; 210(1): 19–23. doi: 10.4049/jimmunol.2200410

PMCID:: PMC9780177

Article PDF–1.1M

Select item 88051472.

Mannose-binding lectin and complement mediate follicular localization and enhanced immunogenicity of diverse protein nanoparticle immunogens

Benjamin J. Read, Lori Won, John C. Kraft, Isaac Sappington, Aereas Aung, Shengwei Wu, Julia Bals, Chengbo Chen, Kelly K. Lee, Daniel Lingwood, Neil P. King, Darrell J. Irvine

Cell Rep. Author manuscript; available in PMC 2022 Feb 1.

Published in final edited form as: Cell Rep. 2022 Jan 11; 38(2): 110217. doi: 10.1016/j.celrep.2021.110217

PMCID:: PMC8805147

Article PDF–2.2M

Select item 82975563.

Dynamic regulation of B cell Complement Signaling is Integral to Germinal Center Responses

Arun Cumpelik, David Heja, Yuan Hu, Gabriele Varano, Farideh Ordikhani, Mark P. Roberto, Zhengxiang He, Dirk Homann, Sergio A. Lira, David Dominguez-Sola, Peter S. Heeger

Nat Immunol. Author manuscript; available in PMC 2021 Nov 24.

Published in final edited form as: Nat Immunol. 2021 Jun; 22(6): 757–768. Published online 2021 May 24. doi: 10.1038/s41590-021-00926-0

PMCID:: PMC8297556

Article PDF–4.9M

Select item 82706734.

Complement Plays a Critical Role in Inflammation-Induced Immunoprophylaxis Failure in Mice

Vicente Escamilla-Rivera, Manjula Santhanakrishnan, Jingchun Liu, David R. Gibb, James E. Forsmo, Ellen F. Foxman, Stephanie C. Eisenbarth, C. John Luckey, James C. Zimring, Krystalyn E. Hudson, Sean R. Stowell, Jeanne E. Hendrickson

Front Immunol. 2021; 12: 704072. Published online 2021 Jun 25. doi: 10.3389/fimmu.2021.704072

PMCID:: PMC8270673

Article PDF–4.6M

Select item 80721175.

A Novel Image Analysis Approach Reveals a Role for Complement Receptors 1 and 2 in Follicular Dendritic Cell Organization in Germinal Centers

Jessica C. Anania, Annika Westin, Jeremy Adler, Birgitta Heyman

Front Immunol. 2021; 12: 655753. Published online 2021 Apr 12. doi: 10.3389/fimmu.2021.655753

PMCID:: PMC8072117

Article PDF–11M

Select item 76105426.

Fibroblastic reticular cell lineage convergence in Peyer’s patches governs intestinal immunity

Alejandro Prados, Lucas Onder, Hung-Wei Cheng, Urs Mörbe, Mechthild Lütge, Cristina Gil-Cruz, Christian Perez-Shibayama, Vasiliki Koliaraki, Burkhard Ludewig, George Kollias

Nat Immunol. Author manuscript; available in PMC 2021 Apr 6.

Published in final edited form as: Nat Immunol. 2021 Apr 1; 22(4): 510–519. Published online 2021 Mar 11. doi: 10.1038/s41590-021-00894-5

PMCID:: PMC7610542

Article PDF–9.1M

Select item 74879697.

A novel mouse model expressing human forms for complement receptors CR1 and CR2

Harriet M. Jackson, Kate E. Foley, Rita O’Rourke, Timothy M. Stearns, Dina Fathalla, B. Paul Morgan, Gareth R. Howell

BMC Genet. 2020; 21: 101. Published online 2020 Sep 9. doi: 10.1186/s12863-020-00893-9

PMCID:: PMC7487969

Article PDF–1.8M

Select item 72757058.

Marginal zone SIGN-R1⁺ macrophages are essential for the maturation of germinal center B cells in the spleen

Gabriela Pirgova, Anne Chauveau, Andrew J. MacLean, Jason G. Cyster, Tal I. Arnon

Proc Natl Acad Sci U S A. 2020 Jun 2; 117(22): 12295–12305. Published online 2020 May 18. doi: 10.1073/pnas.1921673117

PMCID:: PMC7275705

Article PDF–1.6M

Select item 64653679.

Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp

Hung-Wei Cheng, Lucas Onder, Mario Novkovic, Charlotte Soneson, Mechthild Lütge, Natalia Pikor, Elke Scandella, Mark D. Robinson, Jun-ichi Miyazaki, Anne Tersteegen, Ursula Sorg, Klaus Pfeffer, Thomas Rülicke, Thomas Hehlgans, Burkhard Ludewig

Nat Commun. 2019; 10: 1739. Published online 2019 Apr 15. doi: 10.1038/s41467-019-09728-3

PMCID:: PMC6465367

Article PDF–8.3M

Select item 642071910.

Innate immune recognition of glycans targets HIV nanoparticle immunogens to germinal centers

Talar Tokatlian, Benjamin J. Read, Christopher A. Jones, Daniel W. Kulp, Sergey Menis, Jason Y.H. Chang, Jon M. Steichen, Sudha Kumari, Joel D. Allen, Eric L. Dane, Alessia Liguori, Maya Sangesland, Daniel Lingwood, Max Crispin, William R. Schief, Darrell J. Irvine

Science. Author manuscript; available in PMC 2019 Aug 8.

Published in final edited form as: Science. 2019 Feb 8; 363(6427): 649–654. Published online 2018 Dec 20. doi: 10.1126/science.aat9120

PMCID:: PMC6420719

Article PDF–1.6M

Select item 617109911.

Complement C3-Targeted Gene Therapy Restricts Onset and Progression of Neurodegeneration in Chronic Mouse Glaucoma

Alejandra Bosco, Sarah R. Anderson, Kevin T. Breen, Cesar O. Romero, Michael R. Steele, Vince A. Chiodo, Sanford L. Boye, William W. Hauswirth, Stephen Tomlinson, Monica L. Vetter

Mol Ther. 2018 Oct 3; 26(10): 2379–2396. Published online 2018 Aug 24. doi: 10.1016/j.ymthe.2018.08.017

PMCID:: PMC6171099

Article PDF–4.2M

Select item 596452212.

Immunity against the Obligate Intracellular Bacterial Pathogen Rickettsia australis Requires a Functional Complement System

Sean P. Riley, Abigail I. Fish, Fabio Del Piero, Juan J. Martinez

Infect Immun. 2018 Jun; 86(6): e00139-18. Prepublished online 2018 Mar 26. Published online 2018 May 22. doi: 10.1128/IAI.00139-18

PMCID:: PMC5964522

Article PDF–2.2M

Select item 551115313.

IgG3-antigen complexes are deposited on follicular dendritic cells in the presence of C1q and C3

Lu Zhang, Zhoujie Ding, Birgitta Heyman

Sci Rep. 2017; 7: 5400. Published online 2017 Jul 14. doi: 10.1038/s41598-017-05704-3

PMCID:: PMC5511153

Article PDF–5.4M

Select item 471476514.

T cell-independent and T cell-dependent immunoglobulin G responses to polyomavirus infection are impaired in complement receptor 2-deficient mice

Eva Szomolanyi-Tsuda, Mina O. Seedhom, Michael C. Carroll, Robert L. Garcea

Virology. Author manuscript; available in PMC 2016 Jan 15.

Published in final edited form as: Virology. 2006 Aug 15; 352(1): 52–60. Published online 2006 Jun 2. doi: 10.1016/j.virol.2006.04.018

PMCID:: PMC4714765

Article PDF–281K

Select item 466426115.

IgG Suppresses Antibody Responses in Mice Lacking C1q, C3, Complement Receptors 1 and 2, or IgG Fc-Receptors

Joakim J. E. Bergström, Birgitta Heyman

PLoS One. 2015; 10(11): e0143841. Published online 2015 Nov 30. doi: 10.1371/journal.pone.0143841

PMCID:: PMC4664261

Article PDF–490K

Select item 462436416.

Complement receptor 2 is up regulated in the spinal cord following nerve root injury and modulates the spinal cord response

Rickard P. F. Lindblom, Alexander Berg, Mikael Ström, Shahin Aeinehband, Cecilia A. Dominguez, Faiez Al Nimer, Nada Abdelmagid, Matthias Heinig, Johan Zelano, Karin Harnesk, Norbert Hübner, Bo Nilsson, Kristina Nilsson Ekdahl, Margarita Diez, Staffan Cullheim, Fredrik Piehl

J Neuroinflammation. 2015; 12: 192. Published online 2015 Oct 26. doi: 10.1186/s12974-015-0413-6

PMCID:: PMC4624364

Article PDF–3.0M

Select item 430353917.

A new mouse anti-mouse complement receptor type 2 and 1 (CR2/CR1) monoclonal antibody as a tool to study receptor involvement in chronic models of immune responses and disease

Liudmila Kulik, Finnegan B. Hewitt, Van C. Willis, Rosa Rodriguez, Stephen Tomlinson, V. Michael Holers

Mol Immunol. Author manuscript; available in PMC 2016 Feb 1.

Published in final edited form as: Mol Immunol. 2015 Feb; 63(2): 479–488. doi: 10.1016/j.molimm.2014.10.005

PMCID:: PMC4303539

Article PDF–1.2M

Select item 426484218.

TNFa-dependent development of lymphoid tissue in the absence of ROR?t⁺ Lymphoid Tissue Inducer cells

Glaucia C. Furtado, Michelle E. Pacer, Gerold Bongers, Cecile Benezech, Zhengxiang He, Lili Chen, M Cecilia Berin, George Kollias, Jorge H. Caamaño, Sergio A. Lira

Mucosal Immunol. Author manuscript; available in PMC 2014 Dec 12.

Published in final edited form as: Mucosal Immunol. 2014 May; 7(3): 602–614. Published online 2013 Oct 16. doi: 10.1038/mi.2013.79

PMCID:: PMC4264842

Article PDF–3.3M

Select item 413394619.

Generation of a novel Cr2 gene allele by homologous recombination that abrogates production of Cr2 but is sufficient for expression of Cr1

Luke R. Donius, Christopher M. Orlando, Janis J. Weis, John H. Weis

Immunobiology. Author manuscript; available in PMC 2014 Aug 15.

Published in final edited form as: Immunobiology. 2014 Jan; 219(1): 53–63. Published online 2013 Aug 21. doi: 10.1016/j.imbio.2013.08.003

PMCID:: PMC4133946

Article PDF–1.3M

Select item 405041520.

Deficiency of complement receptors CR2/CR1 in Cr2^-/- mice reduces the extent of secondary brain damage after closed head injury

Miriam D Neher, Megan C Rich, Chesleigh N Keene, Sebastian Weckbach, Ashley L Bolden, Justin T Losacco, Jenée Patane, Michael A Flierl, Liudmila Kulik, V Michael Holers, Philip F Stahel

J Neuroinflammation. 2014; 11: 95. Published online 2014 May 24. doi: 10.1186/1742-2094-11-95