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Items: 1 to 20 of 53

1.
Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus
Christopher Szeto, Pirooz Zareie, Rushika C. Wirasinha, Justin B. Zhang, Andrea T. Nguyen, Alan Riboldi-Tunnicliffe, Nicole L. La Gruta, Stephanie Gras, Stephen R. Daley
Nat Commun. 2022; 13: 4951. Published online 2022 Aug 23. doi: 10.1038/s41467-022-32692-4
PMCID:
PMC9399087
ArticlePDF–2.9M
2.
The Tec Kinase Itk Integrates Naïve T Cell Migration and In Vivo Homeostasis
Flavian Thelen, Stefanie Wissmann, Nora Ruef, Jens V. Stein
Front Immunol. 2021; 12: 716405. Published online 2021 Sep 9. doi: 10.3389/fimmu.2021.716405
PMCID:
PMC8458560
ArticlePDF–1001K
3.
Basophils promote barrier dysfunction and resolution in the atopic skin
Christophe Pellefigues, Karmella Naidoo, Palak Mehta, Alfonso J. Schmidt, Ferdinand Jagot, Elsa Roussel, Alissa Cait, Bibek Yumnam, Sally Chappell, Kimberley Meijlink, Mali Camberis, Jean X. Jiang, Gavin Painter, Kara Filbey, Özge Uluçkan, Olivier Gasser, Graham Le Gros
J Allergy Clin Immunol. Author manuscript; available in PMC 2022 Sep 1.
Published in final edited form as: J Allergy Clin Immunol. 2021 Sep; 148(3): 799–812.e10. Published online 2021 Mar 2. doi: 10.1016/j.jaci.2021.02.018
PMCID:
PMC8410897
ArticlePDF–3.1M
4.
Nfkb2 variants reveal a p100-degradation threshold that defines autoimmune susceptibility
Rushika C. Wirasinha, Ainsley R. Davies, Monika Srivastava, Julie M. Sheridan, Xavier Y.X. Sng, Ottavia M. Delmonte, Kerry Dobbs, Khai L. Loh, Lisa A. Miosge, Cindy Eunhee Lee, Rochna Chand, Anna Chan, Jin Yan Yap, Michael D. Keller, Karin Chen, Jamie Rossjohn, Nicole L. La Gruta, Carola G. Vinuesa, Hugh H. Reid, Michail S. Lionakis, Luigi D. Notarangelo, Daniel H.D. Gray, Christopher C. Goodnow, Matthew C. Cook, Stephen R. Daley
J Exp Med. 2021 Feb 1; 218(2): e20200476. Published online 2020 Oct 27. doi: 10.1084/jem.20200476
PMCID:
PMC7595743
ArticlePDF–7.4M
5.
Deletion of self-reactive CCR7– thymocytes in the absence of MHC expression on thymic epithelial cells
Rushika C. Wirasinha, Anna Chan, Jin Yan Yap, Daniel Y. Hu, Charis E. Teh, Daniel H. D. Gray, Christopher C. Goodnow, Stephen R. Daley
Cell Death Differ. 2019 Dec; 26(12): 2727–2739. Published online 2019 Apr 24. doi: 10.1038/s41418-019-0331-8
PMCID:
PMC7224288
ArticlePDF–2.8M
6.
MARCH1-mediated ubiquitination of MHC II impacts the MHC I antigen presentation pathway
Kayla R. Wilson, Haiyin Liu, Geraldine Healey, Vivian Vuong, Satoshi Ishido, Marco J. Herold, Jose A. Villadangos, Justine D. Mintern
PLoS One. 2018; 13(7): e0200540. Published online 2018 Jul 12. doi: 10.1371/journal.pone.0200540
PMCID:
PMC6042767
ArticlePDF–2.2M
7.
Indirect presentation in the thymus limits naive and regulatory T‐cell differentiation by promoting deletion of self‐reactive thymocytes
Jin Yan Yap, Rushika C. Wirasinha, Anna Chan, Debbie R. Howard, Christopher C. Goodnow, Stephen R. Daley
Immunology. 2018 Jul; 154(3): 522–532. Published online 2018 Feb 27. doi: 10.1111/imm.12904
PMCID:
PMC6002238
ArticlePDF–760K
8.
Plasmacytoid dendritic cells induce tolerance predominantly by cargoing antigen to lymph nodes
Karan Kohli, Anika Janssen, Reinhold Förster
Eur J Immunol. 2016 Nov; 46(11): 2659–2668. Published online 2016 Oct 18. doi: 10.1002/eji.201646359
PMCID:
PMC5129535
ArticlePDF–1.0M
9.
A Triad of Molecular Regions Contribute to the Formation of Two Distinct MHC Class II Conformers
Lisa A. Drake, James R. Drake
Mol Immunol. Author manuscript; available in PMC 2017 Jun 1.
Published in final edited form as: Mol Immunol. 2016 Jun; 74: 59–70. Published online 2016 May 2. doi: 10.1016/j.molimm.2016.04.010
PMCID:
PMC4899207
ArticlePDF–1.8M
10.
The QTL within the H2 Complex Involved in the Control of Tuberculosis Infection in Mice Is the Classical Class II H2-Ab1 Gene
Nadezhda Logunova, Maria Korotetskaya, Vladimir Polshakov, Alexander Apt
PLoS Genet. 2015 Nov; 11(11): e1005672. Published online 2015 Nov 30. doi: 10.1371/journal.pgen.1005672
PMCID:
PMC4664271
ArticlePDF–8.4M
11.
Lymph node stromal cells acquire peptide–MHCII complexes from dendritic cells and induce antigen-specific CD4+ T cell tolerance
Juan Dubrot, Fernanda V. Duraes, Lambert Potin, Francesca Capotosti, Dale Brighouse, Tobias Suter, Salomé LeibundGut-Landmann, Natalio Garbi, Walter Reith, Melody A. Swartz, Stéphanie Hugues
J Exp Med. 2014 Jun 2; 211(6): 1153–1166. doi: 10.1084/jem.20132000
PMCID:
PMC4042642
ArticlePDF–2.9M
12.
Rasgrp1 mutation increases naïve T-cell CD44 expression and drives mTOR-dependent accumulation of Helios+ T cells and autoantibodies
Stephen R Daley, Kristen M Coakley, Daniel Y Hu, Katrina L Randall, Craig N Jenne, Andre Limnander, Darienne R Myers, Noelle K Polakos, Anselm Enders, Carla Roots, Bhavani Balakishnan, Lisa A Miosge, Geoff Sjollema, Edward M Bertram, Matthew A Field, Yunli Shao, T Daniel Andrews, Belinda Whittle, S Whitney Barnes, John R Walker, Jason G Cyster, Christopher C Goodnow, Jeroen P Roose
eLife. 2013; 2: e01020. Published online 2013 Dec 12. doi: 10.7554/eLife.01020
PMCID:
PMC3858598
ArticlePDF–6.8M
13.
A Missing PD-L1/PD-1 Coinhibition Regulates Diabetes Induction by Preproinsulin-Specific CD8 T-Cells in an Epitope-Specific Manner
Cornelia Schuster, Helen Brosi, Katja Stifter, Bernhard O. Boehm, Reinhold Schirmbeck
PLoS One. 2013; 8(8): e71746. Published online 2013 Aug 19. doi: 10.1371/journal.pone.0071746
PMCID:
PMC3747217
ArticlePDF–4.0M
14.
MHC Class II–Alpha Chain Knockout Mice Support Increased Viral Replication That Is Independent of Their Lack of MHC Class II Cell Surface Expression and Associated Immune Function Deficiencies
Mohammed Alsharifi, Aulikki Koskinen, Danushka K. Wijesundara, Jayaram Bettadapura, Arno Müllbacher
PLoS One. 2013; 8(6): e68458. Published online 2013 Jun 28. doi: 10.1371/journal.pone.0068458
PMCID:
PMC3695910
ArticlePDF–827K
15.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
ArticlePDF–1.1M
16.
Antigen Recognition By Autoreactive Cd4+ Thymocytes Drives Homeostasis Of The Thymic Medulla
Magali Irla, Lucia Guerri, Jeanne Guenot, Arnauld Sergé, Olivier Lantz, Adrian Liston, Beat A. Imhof, Ed Palmer, Walter Reith
PLoS One. 2012; 7(12): e52591. Published online 2012 Dec 27. doi: 10.1371/journal.pone.0052591
PMCID:
PMC3531460
ArticlePDF–2.4M
17.
The dendritic cell receptor DNGR-1 controls endocytic handling of necrotic cell antigens to favor cross-priming of CTLs in virus-infected mice
Santiago Zelenay, Anna M. Keller, Paul G. Whitney, Barbara U. Schraml, Safia Deddouche, Neil C. Rogers, Oliver Schulz, David Sancho, Caetano Reis e Sousa
J Clin Invest. 2012 May 1; 122(5): 1615–1627. Published online 2012 Apr 16. doi: 10.1172/JCI60644
PMCID:
PMC3336984
ArticlePDF–1.1M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
ArticlePDF–1.0M
19.
MHC class II up-regulation and co-localization with Fas in experimental models of immune-mediated bone marrow failure
Andrew J. Erie, Leigh Samsel, Tomoiku Takaku, Marie J. Desierto, Keyvan Keyvanfar, J. Philip McCoy, Neal S. Young, Jichun Chen
Exp Hematol. Author manuscript; available in PMC 2012 Aug 1.
Published in final edited form as: Exp Hematol. 2011 Aug; 39(8): 837–849. Published online 2011 May 13. doi: 10.1016/j.exphem.2011.05.005
PMCID:
PMC3144292
ArticlePDF–2.8M
20.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
ArticlePDF–3.8M

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