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Select item 108973931.

Cellular reprogramming in vivo initiated by SOX4 pioneer factor activity

Takeshi Katsuda, Jonathan H. Sussman, Kenji Ito, Andrew Katznelson, Salina Yuan, Naomi Takenaka, Jinyang Li, Allyson J. Merrell, Hector Cure, Qinglan Li, Reyaz Ur Rasool, Irfan A. Asangani, Kenneth S. Zaret, Ben Z. Stanger

Nat Commun. 2024; 15: 1761. Published online 2024 Feb 26. doi: 10.1038/s41467-024-45939-z

PMCID:: PMC10897393

Article PDF–12M

Select item 107034192.

Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves

Rachel Queen, Moira Crosier, Lorraine Eley, Janet Kerwin, Jasmin E. Turner, Jianshi Yu, Ahlam Alqahtani, Tamilvendhan Dhanaseelan, Lynne Overman, Hannah Soetjoadi, Richard Baldock, Jonathan Coxhead, Veronika Boczonadi, Alex Laude, Simon J. Cockell, Maureen A. Kane, Steven Lisgo, Deborah J. Henderson

PLoS Genet. 2023 Nov; 19(11): e1010777. Published online 2023 Nov 27. doi: 10.1371/journal.pgen.1010777

PMCID:: PMC10703419

Article PDF–9.6M

Select item 104506573.

SoxC transcription factors shape the epigenetic landscape to establish competence for sensory differentiation in the mammalian organ of Corti

Xizi Wang, Juan Llamas, Talon Trecek, Tuo Shi, Litao Tao, Welly Makmura, J. Gage Crump, Neil Segil, Ksenia Gnedeva

Proc Natl Acad Sci U S A. 2023 Aug 22; 120(34): e2301301120. Published online 2023 Aug 16. doi: 10.1073/pnas.2301301120

PMCID:: PMC10450657

Article PDF–4.8M

Select item 103828604.

Type 2 diabetes susceptibility gene GRK5 regulates physiological pancreatic β-cell proliferation via phosphorylation of HDAC5

Shugo Sasaki, Cuilan Nian, Eric E. Xu, Daniel J. Pasula, Helena Winata, Sanya Grover, Dan S. Luciani, Francis C. Lynn

iScience. 2023 Aug 18; 26(8): 107311. Published online 2023 Jul 10. doi: 10.1016/j.isci.2023.107311

PMCID:: PMC10382860

Article PDF–2.0M

Select item 100419335.

Development and functional characterization of a lncRNA-HIT conditional loss of function allele

Hanqian L. Carlson, H. Scott Stadler

Genesis. Author manuscript; available in PMC 2023 Mar 27.

Published in final edited form as: Genesis. 2020 Mar; 58(3-4): e23351. Published online 2019 Dec 14. doi: 10.1002/dvg.23351

PMCID:: PMC10041933

Article PDF–1.7M

Select item 98887256.

Hepatic ribosomal protein S6 (Rps6) insufficiency results in failed bile duct development and loss of hepatocyte viability; a ribosomopathy-like phenotype that is partially p53-dependent

Sarah A. Comerford, Elizabeth A. Hinnant, Yidong Chen, Robert E. Hammer

PLoS Genet. 2023 Jan; 19(1): e1010595. Published online 2023 Jan 19. doi: 10.1371/journal.pgen.1010595

PMCID:: PMC9888725

Article PDF–6.9M

Select item 98113267.

SOX4 is a novel phenotypic regulator of endothelial cells in atherosclerosis revealed by single-cell analysis

Chak Kwong Cheng, Xiao Lin, Yujie Pu, Joyce Ka Yu Tse, Yu Wang, Cheng-Lin Zhang, Xiaoyun Cao, Chi Wai Lau, Juan Huang, Lei He, Jiang-Yun Luo, Yu-Tsung Shih, Song Wan, Chi Fai Ng, Li Wang, Ronald Ching Wan Ma, Jeng-Jiann Chiu, Ting Fung Chan, Xiao Yu Tian, Yu Huang

J Adv Res. 2023 Jan; 43: 187–203. Published online 2022 Mar 1. doi: 10.1016/j.jare.2022.02.017

PMCID:: PMC9811326

Article PDF–5.9M

Select item 97065828.

SOX4 promotes beige adipocyte-mediated adaptive thermogenesis by facilitating PRDM16-PPARγ complex

Huanming Shen, Ting He, Shuai Wang, Lingfeng Hou, Yixin Wei, Yunjia Liu, Chunli Mo, Zehang Zhao, WeiXin You, Huiling Guo, Boan Li

Theranostics. 2022; 12(18): 7699–7716. Published online 2022 Nov 7. doi: 10.7150/thno.77102

PMCID:: PMC9706582

Article PDF–2.5M

Select item 95952119.

Single-cell atlas of craniogenesis uncovers SOXC-dependent, highly proliferative, and myofibroblast-like osteodermal progenitors

Marco Angelozzi, Renata Pellegrino da Silva, Michael V. Gonzalez, Véronique Lefebvre

Cell Rep. Author manuscript; available in PMC 2022 Oct 25.

Published in final edited form as: Cell Rep. 2022 Jul 12; 40(2): 111045. doi: 10.1016/j.celrep.2022.111045

PMCID:: PMC9595211

Article PDF–4.7M

Select item 934325310.

Temporally divergent regulatory mechanisms govern neuronal diversification and maturation in the mouse and marmoset neocortex

Wen Yuan, Sai Ma, Juliana R. Brown, Kwanho Kim, Vanessa Murek, Lucia Trastulla, Alexander Meissner, Simona Lodato, Ashwin S. Shetty, Joshua Z. Levin, Jason D. Buenrostro, Michael J. Ziller, Paola Arlotta

Nat Neurosci. 2022; 25(8): 1049–1058. Published online 2022 Aug 1. doi: 10.1038/s41593-022-01123-4

PMCID:: PMC9343253

Article PDF–17M

Select item 913244811.

FOXG1 sequentially orchestrates subtype specification of postmitotic cortical projection neurons

Junhua Liu, Mengjie Yang, Mingzhao Su, Bin Liu, Kaixing Zhou, Congli Sun, Ru Ba, Baocong Yu, Baoshen Zhang, Zhe Zhang, Wenxin Fan, Kun Wang, Min Zhong, Junhai Han, Chunjie Zhao

Sci Adv. 2022 May; 8(21): eabh3568. Published online 2022 May 25. doi: 10.1126/sciadv.abh3568

PMCID:: PMC9132448

Article PDF–11M

Select item 907468812.

SOX4 and RELA Function as Transcriptional Partners to Regulate the Expression of TNF- Responsive Genes in Fibroblast-Like Synoviocytes

Kyle Jones, Sergio Ramirez-Perez, Sean Niu, Umesh Gangishetti, Hicham Drissi, Pallavi Bhattaram

Front Immunol. 2022; 13: 789349. Published online 2022 Apr 22. doi: 10.3389/fimmu.2022.789349

PMCID:: PMC9074688

Article PDF–4.6M

Select item 858566813.

Regulation of a progenitor gene program by SOX4 is essential for mammary tumor proliferation

M. Guy Roukens, Cynthia L. Frederiks, Danielle Seinstra, Luca Braccioli, Antoine A. Khalil, Cornelieke Pals, Simon De Neck, Laura Bornes, Evelyne Beerling, Michal Mokry, Alain de Bruin, Bart Westendorp, Jacco van Rheenen, Paul J. Coffer

Oncogene. 2021; 40(45): 6343–6353. Published online 2021 Sep 28. doi: 10.1038/s41388-021-02004-z

PMCID:: PMC8585668

Article PDF–5.8M

Select item 848855614.

Mitotic WNT signalling orchestrates neurogenesis in the developing neocortex

Fabio Da Silva, Kaiqing Zhang, Anneline Pinson, Edoardo Fatti, Michaela Wilsch‐Bräuninger, Jessica Herbst, Valerie Vidal, Andreas Schedl, Wieland B Huttner, Christof Niehrs

EMBO J. 2021 Oct 1; 40(19): e108041. Published online 2021 Aug 25. doi: 10.15252/embj.2021108041

PMCID:: PMC8488556

Article PDF–9.2M

Select item 843797115.

Genetic predisposition to tinnitus in the UK Biobank population

Madeleine E. Urbanek, Jian Zuo

Sci Rep. 2021; 11: 18150. Published online 2021 Sep 13. doi: 10.1038/s41598-021-97350-z

PMCID:: PMC8437971

Article PDF–1.6M

Select item 831323916.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Article PDF–1.6M

Select item 831323317.

HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways

Ryo Miyamoto, Akinori Kanai, Hiroshi Okuda, Yosuke Komata, Satoshi Takahashi, Hirotaka Matsui, Toshiya Inaba, Akihiko Yokoyama

eLife. 2021; 10: e64148. Published online 2021 Jul 26. doi: 10.7554/eLife.64148

PMCID:: PMC8313233

Article PDF–4.4M

Select item 809911218.

Distinct expression of select and transcriptome-wide isolated 3’UTRs suggests critical roles in development and transition states

Shaoyi Ji, Ze Yang, Leonardi Gozali, Thomas Kenney, Arif Kocabas, Carolyn Jinsook Park, Mary Hynes

PLoS One. 2021; 16(5): e0250669. Published online 2021 May 5. doi: 10.1371/journal.pone.0250669

PMCID:: PMC8099112

Article PDF–5.7M

Select item 793589019.

Single cell transcriptomics reveals lineage trajectory of retinal ganglion cells in wild-type and Atoh7-null retinas

Fuguo Wu, Jonathan E. Bard, Julien Kann, Donald Yergeau, Darshan Sapkota, Yichen Ge, Zihua Hu, Jie Wang, Tao Liu, Xiuqian Mu

Nat Commun. 2021; 12: 1465. Published online 2021 Mar 5. doi: 10.1038/s41467-021-21704-4

PMCID:: PMC7935890

Article PDF–5.9M

Select item 788059420.

Usp11 controls cortical neurogenesis and neuronal migration through Sox11 stabilization

Shang-Yin Chiang, Hsin-Chieh Wu, Shu-Yu Lin, Hsin-Yi Chen, Chia-Fang Wang, Nai-Hsing Yeh, Jou-Ho Shih, Yi-Shuian Huang, Hung-Chih Kuo, Shen-Ju Chou, Ruey-Hwa Chen

Sci Adv. 2021 Feb; 7(7): eabc6093. Published online 2021 Feb 12. doi: 10.1126/sciadv.abc6093