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Items: 1 to 20 of 32

1.
Carboxypeptidase E conditional knockout mice exhibit learning and memory deficits and neurodegeneration
Fang-Cheng Fan, Yang Du, Wen-Hui Zheng, Y. Peng Loh, Yong Cheng
Transl Psychiatry. 2023; 13: 135. Published online 2023 Apr 26. doi: 10.1038/s41398-023-02429-y
PMCID:
PMC10133319
ArticlePDF–3.9M
2.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
ArticlePDF–3.3M
3.
Silencing of Carboxypeptidase E expression inhibits proliferation and invasion of Panc-1 pancreatic cancer cells
Hong Lou, Y Peng Loh
Version 2. F1000Res. 2021; 10: 489. Published online 2022 Apr 28. doi: 10.12688/f1000research.53737.2
PMCID:
PMC9069412
ArticlePDF–4.9M
4.
Novel interaction between neurotrophic factor-α1/carboxypeptidase E and serotonin receptor, 5-HTR1E, protects human neurons against oxidative/neuroexcitotoxic stress via β-arrestin/ERK signaling
Vinay Kumar Sharma, Xuyu Yang, Soo-Kyung Kim, Amirhossein Mafi, Daniel Saiz-Sanchez, Patricia Villanueva-Anguita, Lan Xiao, Leila Toulabi, Asuka Inoue, William A. Goddard, III, Y. Peng Loh
Cell Mol Life Sci. 2022; 79(1): 24. Published online 2021 Dec 29. doi: 10.1007/s00018-021-04021-3
Correction in:
Cell Mol Life Sci. 2023; 80(3): 65.
PMCID:
PMC8732845
ArticlePDF–2.1M
5.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
ArticlePDF–2.2M
6.
Secretory Sorting Receptors Carboxypeptidase E and Secretogranin III in Amyloid β‐Associated Neural Degeneration in Alzheimer's Disease
Virginia Plá, Sonia Paco, Gregory Ghezali, Victor Ciria, Esther Pozas, Isidro Ferrer, Fernando Aguado
Brain Pathol. 2013 May; 23(3): 274–284. Published online 2012 Nov 1. doi: 10.1111/j.1750-3639.2012.00644.x
PMCID:
PMC8028878
ArticlePDF–2.0M
7.
Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrPC) in Alzheimer’s disease
Sarah Ulbrich, Petra Janning, Ralf Seidel, Jakob Matschke, Anika Gonsberg, Sebastian Jung, Markus Glatzel, Martin Engelhard, Konstanze F. Winklhofer, Jörg Tatzelt
PLoS One. 2018; 13(5): e0197659. Published online 2018 May 23. doi: 10.1371/journal.pone.0197659
PMCID:
PMC5965872
ArticlePDF–2.4M
8.
Quantitative mapping of RNA-mediated nuclear estrogen receptor β interactome in human breast cancer cells
Giorgio Giurato, Giovanni Nassa, Annamaria Salvati, Elena Alexandrova, Francesca Rizzo, Tuula A. Nyman, Alessandro Weisz, Roberta Tarallo
Sci Data. 2018; 5: 180031. Published online 2018 Mar 6. doi: 10.1038/sdata.2018.31
PMCID:
PMC5839158
ArticlePDF–1.9M
9.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
ArticlePDF–2.7M
10.
A human carboxypeptidase E/NF-α1 gene mutation in an Alzheimer's disease patient leads to dementia and depression in mice
Y Cheng, N X Cawley, T Yanik, S R K Murthy, C Liu, F Kasikci, D Abebe, Y P Loh
Transl Psychiatry. 2016 Dec; 6(12): e973. Published online 2016 Dec 6. doi: 10.1038/tp.2016.237
PMCID:
PMC5315563
ArticlePDF–2.2M
11.
A Novel Single Nucleotide T980C Polymorphism in the Human Carboxypeptidase E Gene Results in Loss of Neuroprotective Function
Lin Cong, Yong Cheng, Niamh X. Cawley, Saravana R. K. Murthy, Y. Peng Loh
PLoS One. 2017; 12(1): e0170169. Published online 2017 Jan 23. doi: 10.1371/journal.pone.0170169
PMCID:
PMC5256889
ArticlePDF–976K
12.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
ArticlePDF–2.2M
13.
The Expression of Hepatic Carboxypeptidase E is Decreased in Patients with Cholesterol Gallstone
Shu-Long Dai, Jin Zhou, Kun-Xing Yang, Shi-Yong Yang
Saudi J Gastroenterol. 2015 Jul-Aug; 21(4): 226–231. doi: 10.4103/1319-3767.161640
PMCID:
PMC4542421
ArticlePDF–1.0M
14.
Carboxypeptidases in disease: Insights from peptidomic studies
Matthew R. Sapio, Lloyd D. Fricker
Proteomics Clin Appl. Author manuscript; available in PMC 2015 Jun 1.
Published in final edited form as: Proteomics Clin Appl. 2014 Jun; 8(0): 327–337. Published online 2014 Mar 24. doi: 10.1002/prca.201300090
PMCID:
PMC4062080
ArticlePDF–276K
15.
Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic β cells
Chong Wee Liew, Anke Assmann, Andrew T. Templin, Jeffrey C. Raum, Kathryn L. Lipson, Sindhu Rajan, Guifen Qiang, Jiang Hu, Dan Kawamori, Iris Lindberg, Louis H. Philipson, Nahum Sonenberg, Allison B. Goldfine, Doris A. Stoffers, Raghavendra G. Mirmira, Fumihiko Urano, Rohit N. Kulkarni
Proc Natl Acad Sci U S A. 2014 Jun 3; 111(22): E2319–E2328. Published online 2014 May 19. doi: 10.1073/pnas.1323066111
PMCID:
PMC4050564
ArticlePDF–1.5M
16.
Upregulation of CPE promotes cell proliferation and tumorigenicity in colorectal cancer
Xing-Hua Liang, Ling-ling Li, Geng-Gang Wu, Yi-Cheng Xie, Guang-Xian Zhang, Wei Chen, Hai-Feng Yang, Qi-Long Liu, Wen-Hong Li, Wen-guang He, Yan-Nian Huang, Xian-Cheng Zeng
BMC Cancer. 2013; 13: 412. Published online 2013 Sep 5. doi: 10.1186/1471-2407-13-412
PMCID:
PMC3844403
ArticlePDF–2.1M
17.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine
Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake
Proteomics. Author manuscript; available in PMC 2014 May 1.
Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561
PMCID:
PMC3773505
ArticlePDF–630K
18.
Carboxypeptidase E: a negative regulator of the canonical Wnt signaling pathway
N Skalka, M Caspi, E Caspi, YP Loh, R Rosin-Arbesfeld
Oncogene. Author manuscript; available in PMC 2013 Jun 7.
Published in final edited form as: Oncogene. 2013 Jun 6; 32(23): 2836–2847. Published online 2012 Jul 23. doi: 10.1038/onc.2012.308
PMCID:
PMC3676431
ArticlePDF–3.1M
19.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
ArticlePDF–1.0M
20.
Association Study of 182 Candidate Genes in Anorexia Nervosa
Andrea Poyastro Pinheiro, Cynthia M. Bulik, Laura M. Thornton, Patrick F. Sullivan, Tammy L. Root, Cinnamon S. Bloss, Wade H. Berrettini, Nicholas J. Schork, Walter H. Kaye, Andrew W. Bergen, Pierre Magistretti, Harry Brandt, Steve Crawford, Scott Crow, Manfred M. Fichter, David Goldman, Katherine A. Halmi, Craig Johnson, Allan S. Kaplan, Pamela K. Keel, Kelly L. Klump, Maria La Via, James E. Mitchell, Michael Strober, Alessandro Rotondo, Janet Treasure, D. Blake Woodside
Am J Med Genet B Neuropsychiatr Genet. Author manuscript; available in PMC 2010 Oct 25.
Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2010 Jul; 153B(5): 1070–1080. doi: 10.1002/ajmg.b.31082
PMCID:
PMC2963154
ArticlePDF–315K

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