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Select item 109734801.

Regulatory T cells expressing CD19-targeted chimeric antigen receptor restore homeostasis in Systemic Lupus Erythematosus

M. Doglio, A. Ugolini, C. Bercher-Brayer, B. Camisa, C. Toma, R. Norata, S. Del Rosso, R. Greco, F. Ciceri, F. Sanvito, M. Casucci, A. A. Manfredi, C. Bonini

Nat Commun. 2024; 15: 2542. Published online 2024 Mar 27. doi: 10.1038/s41467-024-46448-9

PMCID:: PMC10973480

Article PDF–3.9M

Select item 108837742.

SHIP1 deficiency causes inflammation-dependent retardation in skeletal growth

Fatemeh Safari, Wen Jie Yeoh, Saskia Perret-Gentil, Frank Klenke, Silvia Dolder, Willy Hofstetter, Philippe Krebs

Life Sci Alliance. 2024 May; 7(5): e202302297. Published online 2024 Feb 22. doi: 10.26508/lsa.202302297

PMCID:: PMC10883774

Article PDF–13M

Select item 108415813.

Functional screening of amplification outlier oncogenes in organoid models of early tumorigenesis

Ameen A. Salahudeen, Jose A. Seoane, Kanako Yuki, Amanda T. Mah, Amber R. Smith, Kevin Kolahi, Sean M. De la O, Daniel J. Hart, Jie Ding, Zhicheng Ma, Sammy A. Barkal, Navika D. Shukla, Chuck H. Zhang, Michael A. Cantrell, Arpit Batish, Tatsuya Usui, David E. Root, William C. Hahn, Christina Curtis, Calvin J. Kuo

Cell Rep. Author manuscript; available in PMC 2024 Feb 5.

Published in final edited form as: Cell Rep. 2023 Nov 28; 42(11): 113355. Published online 2023 Nov 1. doi: 10.1016/j.celrep.2023.113355

PMCID:: PMC10841581

Article PDF–2.8M

Select item 108367694.

NLGN4X TCR transgenic T cells to treat gliomas

Christoper Krämer, Michael Kilian, Yu-Chan Chih, Alexandros Kourtesakis, Dirk C Hoffmann, Tamara Boschert, Philipp Koopmann, Khwab Sanghvi, Alice De Roia, Stefanie Jung, Kristine Jähne, Bryan Day, Lenny D Shultz, Miriam Ratliff, Richard Harbottle, Edward W Green, Rainer Will, Wolfgang Wick, Michael Platten, Lukas Bunse

Neuro Oncol. 2024 Feb; 26(2): 266–278. Published online 2023 Sep 16. doi: 10.1093/neuonc/noad172

PMCID:: PMC10836769

Article PDF–3.4M

Select item 107626505.

Replication stress and defective checkpoints make fallopian tube epithelial cells putative drivers of high-grade serous ovarian cancer

Pamoda Galhenage, Yunlan Zhou, Erica Perry, Brenda Loc, Kelly Fietz, Sonia Iyer, Ferenc Reinhardt, Tiego Da Silva, Vladimir Botchkarev, Jie Chen, Christopher P. Crum, Robert A. Weinberg, Shailja Pathania

Cell Rep. Author manuscript; available in PMC 2024 Jan 3.

Published in final edited form as: Cell Rep. 2023 Oct 31; 42(10): 113144. Published online 2023 Sep 19. doi: 10.1016/j.celrep.2023.113144

PMCID:: PMC10762650

Article PDF–2.5M

Select item 107094546.

PD-1 signaling negatively regulates the common cytokine receptor γ chain via MARCH5-mediated ubiquitination and degradation to suppress anti-tumor immunity

Rui Liu, Lin-Wen Zeng, Hui-Fang Li, Jun-Ge Shi, Bo Zhong, Hong-Bing Shu, Shu Li

Cell Res. 2023 Dec; 33(12): 923–939. Published online 2023 Nov 6. doi: 10.1038/s41422-023-00890-4

PMCID:: PMC10709454

Article PDF–4.4M

Select item 106886087.

The gut microbiota reprograms intestinal lipid metabolism through long non-coding RNA Snhg9

Yuhao Wang, Meng Wang, Jiaxin Chen, Yun Li, Zheng Kuang, Chaitanya Dende, Prithvi Raj, Gabriella Quinn, Zehan Hu, Tarun Srinivasan, Brian Hassell, Kelly Ruhn, Cassie L. Behrendt, Tingbo Liang, Xiaobing Dou, Zhangfa Song, Lora V. Hooper

Science. Author manuscript; available in PMC 2023 Nov 30.

Published in final edited form as: Science. 2023 Aug 25; 381(6660): 851–857. Published online 2023 Aug 24. doi: 10.1126/science.ade0522

PMCID:: PMC10688608

Article PDF–1.7M

Select item 106171978.

NFAT1 and NFκB regulates expression of the common γ-chain cytokine receptor in activated T cells

Ju A Shim, So Min Lee, Jin Woo Jeong, Hyori Kim, Woo Jae Son, Jun Hong Park, Parkyong Song, Sin-Hyeog Im, Sangsu Bae, Jung-Hyun Park, Yuna Jo, Changwan Hong

Cell Commun Signal. 2023; 21: 309. Published online 2023 Oct 30. doi: 10.1186/s12964-023-01326-7

PMCID:: PMC10617197

Article PDF–5.1M

Select item 106117149.

An immune deficient mouse model for mucopolysaccharidosis IIIA (Sanfilippo syndrome)

Kari Pollock, Sabrina Noritake, Denise M. Imai, Gabrielle Pastenkos, Marykate Olson, Whitney Cary, Sheng Yang, Fernando A. Fierro, Jeannine White, Justin Graham, Heather Dahlenburg, Karl Johe, Jan A. Nolta

Sci Rep. 2023; 13: 18439. Published online 2023 Oct 27. doi: 10.1038/s41598-023-45178-0

PMCID:: PMC10611714

Article PDF–2.7M

Select item 1045619210.

Helicase-like transcription factor (Hltf)-deletion activates Hmgb1-Rage axis and granzyme A-mediated killing of pancreatic β cells resulting in neonatal lethality

Gurvinder Kaur, Rebecca A. Helmer, Dalia Martinez-Marin, Souad R. Sennoune, Rachel L. Washburn, Raul Martinez-Zaguilan, Jannette M. Dufour, Beverly S. Chilton

PLoS One. 2023; 18(8): e0286109. Published online 2023 Aug 25. doi: 10.1371/journal.pone.0286109

PMCID:: PMC10456192

Article PDF–3.7M

Select item 1029212111.

In vivo availability of the cytokine IL-7 constrains the survival and homeostasis of peripheral iNKT cells

Joo-Young Park, Hee Yeun Won, Devon T. DiPalma, Hye Kyung Kim, Tae-Hyoun Kim, Can Li, Noriko Sato, Changwan Hong, Ninan Abraham, Ronald E. Gress, Jung-Hyun Park

Cell Rep. Author manuscript; available in PMC 2023 Jun 26.

Published in final edited form as: Cell Rep. 2022 Jan 11; 38(2): 110219. doi: 10.1016/j.celrep.2021.110219

PMCID:: PMC10292121

Article PDF–2.8M

Select item 1028587912.

KSHV infection drives poorly cytotoxic CD56-negative natural killer cell differentiation in vivo upon KSHV/EBV dual infection

Nicole Caduff, Donal McHugh, Lisa Rieble, Catherine S. Forconi, John M. Ong’echa, Peter O. Oluoch, Ana Raykova, Anita Murer, Michelle Böni, Lara Zuppiger, Thomas F. Schulz, David J. Blackbourn, Obinna Chijioke, Ann M. Moormann, Christian Münz

Cell Rep. Author manuscript; available in PMC 2023 Jun 22.

Published in final edited form as: Cell Rep. 2021 May 4; 35(5): 109056. doi: 10.1016/j.celrep.2021.109056

PMCID:: PMC10285879

Article PDF–1.1M

Select item 1013006013.

Bone marrow endosteal stem cells dictate active osteogenesis and aggressive tumorigenesis

Yuki Matsushita, Jialin Liu, Angel Ka Yan Chu, Chiaki Tsutsumi-Arai, Mizuki Nagata, Yuki Arai, Wanida Ono, Kouhei Yamamoto, Thomas L. Saunders, Joshua D. Welch, Noriaki Ono

Nat Commun. 2023; 14: 2383. Published online 2023 Apr 25. doi: 10.1038/s41467-023-38034-2

PMCID:: PMC10130060

Article PDF–17M

Select item 1011449814.

Regenerative reprogramming of the intestinal stem cell state via Hippo signaling suppresses metastatic colorectal cancer

Priscilla Cheung, Jordi Xiol, Michael T. Dill, Wei-Chien Yuan, Riccardo Panero, Jatin Roper, Fernando G. Osorio, Dejan Maglic, Qi Li, Basanta Gurung, Raffaele A. Calogero, Ömer H. Yilmaz, Junhao Mao, Fernando D. Camargo

Cell Stem Cell. Author manuscript; available in PMC 2023 Apr 19.

Published in final edited form as: Cell Stem Cell. 2020 Oct 1; 27(4): 590–604.e9. Published online 2020 Jul 29. doi: 10.1016/j.stem.2020.07.003

PMCID:: PMC10114498

Article PDF–2.4M

Select item 1009656515.

An RNA-based system to study hepatitis B virus replication and evaluate antivirals

Yingpu Yu, William M. Schneider, Maximilian A. Kass, Eleftherios Michailidis, Ashley Acevedo, Ana L. Pamplona Mosimann, Juliano Bordignon, Alexander Koenig, Christine M. Livingston, Hardeep van Gijzel, Yi Ni, Pradeep M. Ambrose, Catherine A. Freije, Mengyin Zhang, Chenhui Zou, Mohammad Kabbani, Corrine Quirk, Cyprien Jahan, Xianfang Wu, Stephan Urban, Shihyun You, Amir Shlomai, Ype P. de Jong, Charles M. Rice

Sci Adv. 2023 Apr; 9(15): eadg6265. Published online 2023 Apr 12. doi: 10.1126/sciadv.adg6265

PMCID:: PMC10096565

Article PDF–1.1M

Select item 1003492116.

hPSC-derived Sacral Neural Crest Enables Rescue in a Severe Model of Hirschsprung’s Disease

Yujie Fan, James Hackland, Arianna Baggiolini, Lin Y Hung, Huiyong Zhao, Paul Zumbo, Polina Oberst, Andrew P. Minotti, Emiliano Hergenreder, Sarah Najjar, Zixing Huang, Nelly M. Cruz, Aaron Zhong, Mega Sidharta, Ting Zhou, Elisa de Stanchina, Doron Betel, Richard M White, Michael Gershon, Kara Gross Margolis, Lorenz Studer

Cell Stem Cell. Author manuscript; available in PMC 2024 Mar 2.

Published in final edited form as: Cell Stem Cell. 2023 Mar 2; 30(3): 264–282.e9. doi: 10.1016/j.stem.2023.02.003

PMCID:: PMC10034921

Article PDF–1.9M

Select item 988981417.

Behavioral and cognitive performance of humanized APOEε3/ε3 liver mice in relation to plasma apolipoprotein E levels

Kat Kessler, Andreas Giannisis, Greg Bial, Lander Foquet, Henrietta M. Nielsen, Jacob Raber

Sci Rep. 2023; 13: 1728. Published online 2023 Jan 31. doi: 10.1038/s41598-023-28165-3

PMCID:: PMC9889814

Article PDF–9.4M

Select item 983936218.

Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22

Anastasios D. Giannou, Jan Kempski, Ahmad Mustafa Shiri, Jöran Lücke, Tao Zhang, Lilan Zhao, Dimitra E. Zazara, Filippo Cortesi, Kristoffer Riecken, Maria Carolina Amezcua Vesely, Jun Siong Low, Hao Xu, Eleanna Kaffe, Laura Garcia-Perez, Theodora Agalioti, Yoshito Yamada, Wolfgang Jungraithmayr, Ehud Zigmond, Karl-Frederick Karstens, Babett Steglich, Jonas Wagner, Leonie Konczalla, Antonella Carambia, Kornelius Schulze, Johann von Felden, Peter May, Daria Briukhovetska, Tanja Bedke, Leonie Brockmann, Sarah Starzonek, Tobias Lange, Claudia Koch, Sabine Riethdorf, Penelope Pelczar, Marius Böttcher, Morsal Sabihi, Francis J. Huber, Matthias Reeh, Julia Kristin Grass, Ramez Wahib, Hannes Seese, Björn-Ole Stüben, Mohammad Fard-Aghaie, Anna Duprée, Pasquale Scognamiglio, Gabriel Plitzko, Jan Meiners, Shiwa Soukou, Agnes Wittek, Caroline Manthey, Ioannis C. Maroulis, Petra C. Arck, Daniel Perez, Bin Gao, Sotirios G. Zarogiannis, Till Strowig, Renata Pasqualini, Wadih Arap, Javier Suárez Gosálvez, Sebastian Kobold, Immo Prinz, Andreas H. Guse, Michael Tachezy, Tarik Ghadban, Asmus Heumann, Jun Li, Nathaniel Melling, Oliver Mann, Jakob R. Izbicki, Klaus Pantel, Udo Schumacher, Ansgar W. Lohse, Richard A. Flavell, Nicola Gagliani, Samuel Huber

Immunity. 2023 Jan 10; 56(1): 125–142.e12. doi: 10.1016/j.immuni.2022.12.014

PMCID:: PMC9839362

Article

Select item 983744219.

Antigen-guided depletion of anti-HLA antibody–producing cells by HLA-Fc fusion proteins

Ashlee M. Webber, Tara R. Bradstreet, Xiaoli Wang, Hongjie Guo, Christopher A. Nelson, Daved H. Fremont, Brian T. Edelson, Chang Liu

Blood. 2022 Oct 20; 140(16): 1803–1815. Published online 2022 Aug 18. doi: 10.1182/blood.2022016376

PMCID:: PMC9837442

Article

Select item 981919720.

Lipid-Laden Lung Mesenchymal Cells Foster Breast Cancer Metastasis via Metabolic Reprogramming of Tumor Cells and Natural Killer Cells

Zheng Gong, Qing Li, Jiayuan Shi, Edison T. Liu, Leonard D. Shultz, Guangwen Ren

Cell Metab. Author manuscript; available in PMC 2023 Dec 6.

Published in final edited form as: Cell Metab. 2022 Dec 6; 34(12): 1960–1976.e9. doi: 10.1016/j.cmet.2022.11.003

PMCID:: PMC9819197

Article PDF–3.2M

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