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Items: 1 to 20 of 716

1.
Genetic determinants of blood pressure and heart rate identified through ENU-induced mutagenesis with automated meiotic mapping
Samantha K. Teixeira, Roberto Pontes, Luiz Fernando G. Zuleta, Jianhui Wang, Darui Xu, Sara Hildebrand, Jamie Russell, Xiaoming Zhan, Mihwa Choi, Miao Tang, Xiaohong Li, Sara Ludwig, Bruce Beutler, Jose E. Krieger
Sci Adv. 2024 Mar 1; 10(9): eadj9797. Published online 2024 Mar 1. doi: 10.1126/sciadv.adj9797
PMCID:
PMC10906923
ArticlePDF–2.3M
2.
Socrates: A Novel N-Ethyl-N-nitrosourea-Induced Mouse Mutant with Audiogenic Epilepsy
Elena G. Varlamova, Ekaterina V. Borisova, Yuliya A. Evstratova, Andrew G. Newman, Vera P. Kuldaeva, Maria S. Gavrish, Elena V. Kondakova, Victor S. Tarabykin, Alexey A. Babaev, Egor A. Turovsky
Int J Mol Sci. 2023 Dec; 24(23): 17104. Published online 2023 Dec 4. doi: 10.3390/ijms242317104
PMCID:
PMC10707124
ArticlePDF–6.0M
3.
EGR1 haploinsufficiency confers a fitness advantage to hematopoietic stem cells following chemotherapy
Angela Stoddart, Anthony A. Fernald, Elizabeth M. Davis, Megan E. McNerney, Michelle M. Le Beau
Exp Hematol. Author manuscript; available in PMC 2023 Nov 1.
Published in final edited form as: Exp Hematol. 2022 Nov; 115: 54–67. Published online 2022 Aug 20. doi: 10.1016/j.exphem.2022.08.003
PMCID:
PMC10617250
ArticlePDF–2.9M
4.
Identification and Analysis of a Four-Gene Set for Diagnosing SFTS Virus Infection Based on Machine Learning Methods and Its Association with Immune Cell Infiltration
Tao Huang, Xueqi Wang, Yuqian Mi, Tiezhu Liu, Yang Li, Ruixue Zhang, Zhen Qian, Yanhan Wen, Boyang Li, Lina Sun, Wei Wu, Jiandong Li, Shiwen Wang, Mifang Liang
Viruses. 2023 Oct; 15(10): 2126. Published online 2023 Oct 20. doi: 10.3390/v15102126
PMCID:
PMC10612101
ArticlePDF–5.9M
5.
Reconstructed human intestinal comet assay, a possible alternative in vitro model for genotoxicity assessment
Christopher Owen Hughes, Hui Kheng Lim, Joseph Choon Wee Tan, David Ian Leavesley, Benjamin Paul Chapman Smith
Mutagenesis. 2023 May; 38(3): 139–150. Published online 2023 Apr 28. doi: 10.1093/mutage/gead011
PMCID:
PMC10281391
ArticlePDF–714K
6.
Determination of potential thresholds for N-ethyl-N-nitrosourea and ethyl methanesulfonate based on a multi-endpoint genotoxicity assessment platform in rats
Xuejiao Zhu, Jiao Huo, Zhu Zeng, Yunjie Liu, Ruirui Li, Yiyi Chen, Lishi Zhang, Jinyao Chen
Environ Sci Pollut Res Int. 2022; 29(56): 85128–85142. Published online 2022 Jul 6. doi: 10.1007/s11356-022-21605-z
PMCID:
PMC9646607
ArticlePDF–2.2M
7.
Gene mining of immune microenvironment in hepatocellular carcinoma
Zhi-Wei Xu
Medicine (Baltimore) 2022 Sep 2; 101(35): e30453. Published online 2022 Sep 2. doi: 10.1097/MD.0000000000030453
PMCID:
PMC9439754
ArticlePDF–2.0M
8.
Modulation of autoimmune diabetes by N-ethyl-N-nitrosourea- induced mutations in non-obese diabetic mice
Lucienne Chatenoud, Cindy Marquet, Fabrice Valette, Lindsay Scott, Jiexia Quan, Chun Hui Bu, Sara Hildebrand, Eva Marie Y. Moresco, Jean-François Bach, Bruce Beutler
Dis Model Mech. 2022 Jun 1; 15(6): dmm049484. Published online 2022 Jun 1. doi: 10.1242/dmm.049484
PMCID:
PMC9178510
Article
9.
Germline saturation mutagenesis induces skeletal phenotypes in mice
Jonathan J Rios, Kristin Denton, Jamie Russell, Julia Kozlitina, Carlos R Ferreira, Amy F Lewanda, Joshua E Mayfield, Eva Moresco, Sara Ludwig, Miao Tang, Xiaohong Li, Stephen Lyon, Anas Khanshour, Nandina Paria, Aysha Khalid, Yang Li, Xudong Xie, Jian Q Feng, Qian Xu, Yongbo Lu, Robert E Hammer, Carol A Wise, Bruce Beutler
J Bone Miner Res. Author manuscript; available in PMC 2022 Aug 1.
Published in final edited form as: J Bone Miner Res. 2021 Aug; 36(8): 1548–1565. Published online 2021 May 10. doi: 10.1002/jbmr.4323
PMCID:
PMC8862308
ArticlePDF–2.5M
10.
A Non-Rogue Mutant Line Induced by ENU Mutagenesis in Paramutated Rogue Peas (Pisum sativum L.) Is Still Sensitive to the Rogue Paramutation
Ricardo Pereira, José M. Leitão
Genes (Basel) 2021 Nov; 12(11): 1680. Published online 2021 Oct 23. doi: 10.3390/genes12111680
PMCID:
PMC8623080
ArticlePDF–2.5M
11.
An L314Q mutation in Map3k1 gene results in failure of eyelid fusion in the N-ethyl-N-nitrosourea-induced mutant line
Bing Chen, Hong-Ling Wang, Rui Chen, Li Chen, Shun Yang, Yi Wang, Zheng-Feng Xue
Exp Anim. 2021; 70(4): 459–468. Published online 2021 Jun 2. doi: 10.1538/expanim.21-0005
PMCID:
PMC8614015
ArticlePDF–4.5M
12.
The Tpl2 mutation Sluggish impairs type I interferon production and increases susceptibility to group B streptococcal disease
Nengming Xiao, Celine Eidenschenk, Philippe Krebs, Katharina Brandl, Amanda L. Blasius, Yu Xia, Kevin Khovananth, Nora G. Smart, Bruce Beutler
J Immunol. Author manuscript; available in PMC 2021 Sep 8.
Published in final edited form as: J Immunol. 2009 Dec 15; 183(12): 7975–7983. doi: 10.4049/jimmunol.0902718
PMCID:
PMC8424661
ArticlePDF–2.2M
13.
Histologic Distribution and Characteristics on MR Imaging of Ultrasmall Superparamagnetic Iron Oxide in Ethyl-nitrosourea-induced Endogenous Rat Glioma
Atsuko Yamamoto, Kai Takaki, Shigehiro Morikawa, Kiyoshi Murata, Ryuta Ito
Magn Reson Med Sci. 2021; 20(3): 264–271. Published online 2020 Aug 21. doi: 10.2463/mrms.mp.2019-0134
PMCID:
PMC8424023
ArticlePDF–15M
14.
Endocytic Protein Defects in the Neural Crest Cell Lineage and Its Pathway Are Associated with Congenital Heart Defects
Angelo B. Arrigo, Jiuann-Huey Ivy Lin
Int J Mol Sci. 2021 Aug; 22(16): 8816. Published online 2021 Aug 16. doi: 10.3390/ijms22168816
PMCID:
PMC8396181
ArticlePDF–1.1M
15.
Dyke Award Paper. Kinetics of pathologic blood-brain-barrier permeability in an astrocytic glioma using contrast-enhanced MR.
U P Schmiedl, J Kenney, K R Maravilla
AJNR Am J Neuroradiol. 1992 Jan-Feb; 13(1): 5-14.
PMCID:
PMC8331779
SummaryPDF–6.0M
16.
Development of an early induction model of medulloblastoma in Ptch1 heterozygous mice initiated with N‐ethyl‐N‐nitrosourea
Miwa Takahashi, Saori Matsuo, Kaoru Inoue, Kei Tamura, Kaoru Irie, Yukio Kodama, Midori Yoshida
Cancer Sci. 2012 Dec; 103(12): 2051–2055. Published online 2012 Oct 30. doi: 10.1111/cas.12006
PMCID:
PMC7659221
ArticlePDF–339K
17.
Novel mouse model for Gardner syndrome generated by a large‐scale N‐ethyl‐N‐nitrosourea mutagenesis program
Hideaki Toki, Maki Inoue, Hiromi Motegi, Osamu Minowa, Hiroaki Kanda, Noriko Yamamoto, Ami Ikeda, Yuko Karashima, Junko Matsui, Hideki Kaneda, Ikuo Miura, Tomohiro Suzuki, Shigeharu Wakana, Hiroshi Masuya, Yoichi Gondo, Toshihiko Shiroishi, Tetsu Akiyama, Ryoji Yao, Tetsuo Noda
Cancer Sci. 2013 Jul; 104(7): 937–944. Published online 2013 May 18. doi: 10.1111/cas.12161
PMCID:
PMC7657124
ArticlePDF–1.8M
18.
Forward genetic analysis using OCT screening identifies Sfxn3 mutations leading to progressive outer retinal degeneration in mice
Bo Chen, Bogale Aredo, Yi Ding, Xin Zhong, Yuanfei Zhu, Cynthia X. Zhao, Ashwani Kumar, Chao Xing, Laurent Gautron, Stephen Lyon, Jamie Russell, Xiaohong Li, Miao Tang, Priscilla Anderton, Sara Ludwig, Eva Marie Y. Moresco, Bruce Beutler, Rafael L. Ufret-Vincenty
Proc Natl Acad Sci U S A. 2020 Jun 9; 117(23): 12931–12942. Published online 2020 May 26. doi: 10.1073/pnas.1921224117
PMCID:
PMC7293615
ArticlePDF–3.1M
19.
Machine Learning Techniques for Classifying the Mutagenic Origins of Point Mutations
Yicheng Zhu, Cheng Soon Ong, Gavin A. Huttley
Genetics. 2020 May; 215(1): 25–40. Published online 2020 Mar 19. doi: 10.1534/genetics.120.303093
PMCID:
PMC7198283
ArticlePDF–1.4M
20.
Essential requirement for nicastrin in marginal zone and B-1 B cell development
Jin Huk Choi, Jonghee Han, Panayotis C. Theodoropoulos, Xue Zhong, Jianhui Wang, Dawson Medler, Sara Ludwig, Xiaoming Zhan, Xiaohong Li, Miao Tang, Thomas Gallagher, Gang Yu, Bruce Beutler
Proc Natl Acad Sci U S A. 2020 Mar 3; 117(9): 4894–4901. Published online 2020 Feb 18. doi: 10.1073/pnas.1916645117
PMCID:
PMC7060662
ArticlePDF–1.7M

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