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Items: 1 to 20 of 4468

1.
Generation and characterization of antagonistic anti-human CD39 nanobodies
Stephan Menzel, Yinghui Duan, Julia Hambach, Birte Albrecht, Dorte Wendt-Cousin, Riekje Winzer, Eva Tolosa, Anne Rissiek, Andreas H. Guse, Friedrich Haag, Tim Magnus, Friedrich Koch-Nolte, Björn Rissiek
Front Immunol. 2024; 15: 1328306. Published online 2024 Mar 25. doi: 10.3389/fimmu.2024.1328306
PMCID:
PMC11000232
ArticlePDF–2.7M
2.
Ticagrelor inverse agonist activity at the P2Y12 receptor is non‐reversible versus its endogenous agonist adenosine 5´‐diphosphate
Jawad Khalil, Tudor Dimofte, Timothy Roberts, Michael Keith, Kumuthu Amaradasa, Matthew S. Hindle, Sukhinder Bancroft, James L. Hutchinson, Khalid Naseem, Thomas Johnson, Stuart J. Mundell
Br J Pharmacol. 2024 Jan; 181(1): 21–35. Published online 2023 Sep 1. doi: 10.1111/bph.16204
PMCID:
PMC10953389
ArticlePDF–2.7M
3.
Exploring bias in platelet P2Y1 signalling: Host defence versus haemostasis
Dingxin Pan, Graham Ladds, Khondaker Miraz Rahman, Simon C. Pitchford
Br J Pharmacol. 2024 Feb; 181(4): 580–592. Published online 2023 Aug 2. doi: 10.1111/bph.16191
PMCID:
PMC10952580
ArticlePDF–1.6M
4.
Stimulation of platelet P2Y1 receptors by different endogenous nucleotides leads to functional selectivity via biased signalling
Kate L. Arkless, Dingxin Pan, Manu Shankar‐Hari, Richard T. Amison, Clive P. Page, Khondaker Miraz Rahman, Simon C. Pitchford
Br J Pharmacol. 2024 Feb; 181(4): 564–579. Published online 2023 Feb 13. doi: 10.1111/bph.16039
PMCID:
PMC10952403
ArticlePDF–2.6M
5.
Solid‐Phase Synthesis and Biological Evaluation of Peptides ADP‐Ribosylated at Histidine
Hugo Minnee, Johannes G. M. Rack, Gijsbert A. van der Marel, Herman S. Overkleeft, Jeroen D. C. Codée, Ivan Ahel, Dmitri V. Filippov
Angew Chem Int Ed Engl. 2024 Jan 22; 63(4): e202313317. Published online 2023 Nov 14. doi: 10.1002/anie.202313317
PMCID:
PMC10952301
ArticlePDF–3.5M
6.
New insights into the structure and function of the complex between the Escherichia coli Hsp70, DnaK, and its nucleotide-exchange factor, GrpE
Maria-Agustina Rossi, Alexandra K. Pozhidaeva, Eugenia M. Clerico, Constantine Petridis, Lila M. Gierasch
J Biol Chem. 2024 Jan; 300(1): 105574. Published online 2023 Dec 16. doi: 10.1016/j.jbc.2023.105574
PMCID:
PMC10825016
ArticlePDF–2.9M
7.
The Effect of Platelet Activity, ABCB1 Genetic Polymorphism, and Renal Function on the Development of Ticagrelor-Related Dyspnea in Patients with Acute Coronary Syndrome
Vytenis Tamakauskas, Remigijus Žaliūnas, Vaiva Lesauskaitė, Nora Kupstytė-Krištaponė, Ieva Čiapienė, Gintarė Šakalytė, Jurgita Plisienė, Vilius Skipskis, Vacis Tatarūnas
Drug Des Devel Ther. 2024; 18: 109–119. Published online 2024 Jan 23. doi: 10.2147/DDDT.S435477
PMCID:
PMC10822766
ArticlePDF–2.5M
8.
GDF-15 Inhibits ADP-Induced Human Platelet Aggregation through the GFRAL/RET Signaling Complex
Baikang Xie, Wenjing Tang, Shuang Wen, Fen Chen, Chao Yang, Min Wang, Yong Yang, Wei Liang
Biomolecules. 2024 Jan; 14(1): 38. Published online 2023 Dec 27. doi: 10.3390/biom14010038
PMCID:
PMC10813690
ArticlePDF–2.4M
9.
Modulation of Cellular Levels of Adenosine Phosphates and Creatine Phosphate in Cultured Primary Astrocytes
Gabriele Karger, Julius Berger, Ralf Dringen
Neurochem Res. 2024; 49(2): 402–414. Published online 2023 Oct 19. doi: 10.1007/s11064-023-04039-y
PMCID:
PMC10787699
ArticlePDF–2.4M
10.
Computer-aided analysis of biochemical mechanisms that increase metabolite and proton stability in the heart during severe hypoxia and generate post-ischemic PCr overshoot
Bernard Korzeniewski
J Physiol Sci. 2011 Sep; 61(5): 349–361. Published online 2011 Jun 11. doi: 10.1007/s12576-011-0151-1
PMCID:
PMC10717760
ArticlePDF–368K
11.
Rat and mouse cardiomyocytes show subtle differences in creatine kinase expression and compartmentalization
Jelena Branovets, Kärol Soodla, Marko Vendelin, Rikke Birkedal
PLoS One. 2023; 18(11): e0294718. Published online 2023 Nov 27. doi: 10.1371/journal.pone.0294718
PMCID:
PMC10681188
ArticlePDF–1.4M
12.
Compartmentalization of adenosine metabolism in cancer cells and its modulation during acute hypoxia
Karolina Losenkova, Mariachiara Zuccarini, Marika Karikoski, Juha Laurila, Detlev Boison, Sirpa Jalkanen, Gennady G. Yegutkin
J Cell Sci. 2020 May 15; 133(10): jcs241463. Published online 2020 May 29. doi: 10.1242/jcs.241463
PMCID:
PMC10681022
Article
13.
The mitochondrially targeted peptide elamipretide (SS-31) improves ADP sensitivity in aged mitochondria by increasing uptake through the adenine nucleotide translocator (ANT)
Gavin Pharaoh, Varun Kamat, Sricharan Kannan, Rudolph S. Stuppard, Jeremy Whitson, Miguel Martín-Pérez, Wei-Jun Qian, Michael J. MacCoss, Judit Villén, Peter Rabinovitch, Matthew D. Campbell, Ian R. Sweet, David J. Marcinek
GeroScience. 2023 Dec; 45(6): 3529–3548. Published online 2023 Jul 18. doi: 10.1007/s11357-023-00861-y
PMCID:
PMC10643647
ArticlePDF–1.8M
14.
Molecular mechanisms of inorganic-phosphate release from the core and barbed end of actin filaments
Wout Oosterheert, Florian E. C. Blanc, Ankit Roy, Alexander Belyy, Micaela Boiero Sanders, Oliver Hofnagel, Gerhard Hummer, Peter Bieling, Stefan Raunser
Nat Struct Mol Biol. 2023; 30(11): 1774–1785. Published online 2023 Sep 25. doi: 10.1038/s41594-023-01101-9
PMCID:
PMC10643162
ArticlePDF–30M
15.
In-vitro antiplatelet effect of melatonin in healthy individuals and patients with type 2 diabetes mellitus
A. Böhm, V. Lauko, K. Dostalova, I. Balanova, I. Varga, B. Bezak, N. Jajcay, R. Moravcik, L. Lazurova, P. Slezak, V. Mojto, M. Kollarova, K. Petrikova, K. Danova, M. Zeman
J Endocrinol Invest. 2023; 46(12): 2493–2500. Published online 2023 May 6. doi: 10.1007/s40618-023-02102-7
PMCID:
PMC10632203
ArticlePDF–1.0M
16.
Serine 31 Phosphorylation-Driven Regulation of AGPase Activity: Potential Implications for Enhanced Starch Yields in Crops
Guowu Yu, Yuewei Mou, Noman Shoaib, Xuewu He, Lun Liu, Runze Di, Nishbah Mughal, Na Zhang, Yubi Huang
Int J Mol Sci. 2023 Oct; 24(20): 15283. Published online 2023 Oct 18. doi: 10.3390/ijms242015283
PMCID:
PMC10607544
ArticlePDF–3.2M
17.
Activation of P2Y1R impedes intestinal mucosa repair during colitis
Qiuchan Huan, Jiao Peng, Yaoyao Chang, Qiansheng Zhang, Tianhang Xing, Danling Jiang, Wenke Chen, Xiangchun Shen, Zhaoxiang Bian, Haitao Xiao
Int J Biol Sci. 2023; 19(14): 4360–4375. Published online 2023 Aug 21. doi: 10.7150/ijbs.82302
PMCID:
PMC10535714
ArticlePDF–8.9M
18.
A plasma membrane-associated glycolytic metabolon is functionally coupled to KATP channels in pancreatic α and β cells from humans and mice
Thuong Ho, Evgeniy Potapenko, Dawn B. Davis, Matthew J. Merrins
Cell Rep. Author manuscript; available in PMC 2023 Sep 21.
Published in final edited form as: Cell Rep. 2023 Apr 25; 42(4): 112394. Published online 2023 Apr 13. doi: 10.1016/j.celrep.2023.112394
PMCID:
PMC10513404
ArticlePDF–1.4M
19.
Human mitochondrial ADP/ATP carrier SLC25A4 operates with a ping‐pong kinetic mechanism
Camila Cimadamore‐Werthein, Stephany Jaiquel Baron, Martin S King, Roger Springett, Edmund RS Kunji
EMBO Rep. 2023 Aug; 24(8): e57127. Published online 2023 Jun 6. doi: 10.15252/embr.202357127
PMCID:
PMC10398649
ArticlePDF–1.1M
20.
Being Overweight or Obese Is Associated with an Increased Platelet Reactivity Despite Dual Antiplatelet Therapy with Aspirin and Clopidogrel
Marianna Puccini, Christian Rauch, Kai Jakobs, Julian Friebel, Adel Hassanein, Ulf Landmesser, Ursula Rauch
Cardiovasc Drugs Ther. 2023; 37(4): 833–837. Published online 2022 Feb 25. doi: 10.1007/s10557-022-07325-z
PMCID:
PMC10397124
ArticlePDF–540K

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