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PMC Full-Text Search Results

Items: 1 to 20 of 216

1.
A New Spectral Shift-Based Method to Characterize Molecular Interactions
Andreas Langer, Tanja Bartoschik, Ondrej Cehlar, Stefan Duhr, Philipp Baaske, Werner Streicher
Assay Drug Dev Technol. February/March 2022; 20(2): 83–94. Published online 2022 Mar 8. doi: 10.1089/adt.2021.133
Correction in:
Assay Drug Dev Technol. April 2022; 20(3): 136.
PMCID:
PMC8968852
ArticlePDF–2.8M
2.
Modifications to the Transwell Migration/Invasion Assay Method That Eases Assay Performance and Improves the Accuracy
Heidi Marie Stoellinger, Arshak R. Alexanian
Assay Drug Dev Technol. February/March 2022; 20(2): 75–82. Published online 2022 Mar 8. doi: 10.1089/adt.2021.140
PMCID:
PMC8968842
ArticlePDF–1.0M
3.
Correction to: Novel Insight into Potential Leishmanicidal Activities of Transdermal Patches of Nigella Sativa: Formulation Development, Physical Characterizations, and In vitro/In vivo Assays by Kahn et al. Assay Drug Dev Technol. 2021;19:339–349. DOI: 10.1089/adt.2021.035
Assay Drug Dev Technol. January 2022; 20(1): 64–65. Published online 2022 Jan 12. doi: 10.1089/adt.2021.035.correx
Corrects:
Assay Drug Dev Technol. 2021 Jun 28
PMCID:
PMC8787698
CorrectionPDF–73K
4.
A Genome-Edited ERα-HiBiT Fusion Reporter Cell Line for the Identification of ERα Modulators Via High-Throughput Screening and CETSA
Hunter G. Larson, Alexey V. Zakharov, Sukumar Sarkar, Shyh-Ming Yang, Ganesha Rai, James M. Larner, Anton Simeonov, Natalia J. Martinez
Assay Drug Dev Technol. November/December 2021; 19(8): 539–549. Published online 2021 Dec 8. doi: 10.1089/adt.2021.059
PMCID:
PMC8713567
ArticlePDF–892K
5.
In Vitro Release Testing of Acyclovir Topical Formulations Using Immersion Cells
Madhur Kulkarni, Shrikant Potdar, Abhijit A. Date, Aditya Marfatiya
Assay Drug Dev Technol. February/March 2021; 19(2): 75–84. Published online 2021 Mar 12. doi: 10.1089/adt.2020.995
PMCID:
PMC8020522
ArticlePDF–533K
6.
Individuating Possibly Repurposable Drugs and Drug Targets for COVID-19 Treatment Through Hypothesis-Driven Systems Medicine Using CoVex
Julian Matschinske, Marisol Salgado-Albarrán, Sepideh Sadegh, Dario Bongiovanni, Jan Baumbach, David B. Blumenthal
Assay Drug Dev Technol. November/December 2020; 18(8): 348–355. Published online 2020 Nov 30. doi: 10.1089/adt.2020.1010
PMCID:
PMC7703307
ArticlePDF–511K
7.
A Fully Integrated Assay Panel for Early Drug Metabolism and Pharmacokinetics Profiling
Johan Wernevik, Fredrik Bergström, Anna Novén, Johan Hulthe, Linda Fredlund, Dan Addison, Jan Holmgren, Per-Erik Strömstedt, Erika Rehnström, Thomas Lundbäck
Assay Drug Dev Technol. May/June 2020; 18(4): 157–179. Published online 2020 May 20. doi: 10.1089/adt.2020.970
PMCID:
PMC7567642
ArticlePDF–2.2M
8.
Development of a QPatch-Automated Electrophysiology Assay for Identifying TMEM16A Small-Molecule Inhibitors
Kathryn A. Henckels, David Fong, Jonathan E. Phillips
Assay Drug Dev Technol. April 2020; 18(3): 134–147. Published online 2020 Apr 17. doi: 10.1089/adt.2019.962
PMCID:
PMC7268545
ArticlePDF–1.6M
9.
The Promise and Perils of Compound Discovery Screening with Inducible Pluripotent Cell-Derived Neurons
Elizabeth R. Sharlow, Mehmet Murat Koseoglu, George S. Bloom, John S. Lazo
Assay Drug Dev Technol. February/March 2020; 18(2): 97–103. Published online 2020 Feb 14. doi: 10.1089/adt.2019.914
PMCID:
PMC7047103
ArticlePDF–449K
10.
Automated Machine Learning Diagnostic Support System as a Computational Biomarker for Detecting Drug-Induced Liver Injury Patterns in Whole Slide Liver Pathology Images
Munish Puri
Assay Drug Dev Technol. January 2020; 18(1): 1–10. Published online 2020 Jan 21. doi: 10.1089/adt.2019.919
PMCID:
PMC6998050
ArticlePDF–640K
11.
Fenugreek Leaf Extract and Its Gel Formulation Show Activity Against Malassezia furfur
Madhur Kulkarni, Vishakha Hastak, Vitthal Jadhav, Abhijit A. Date
Assay Drug Dev Technol. January 2020; 18(1): 45–55. Published online 2020 Jan 21. doi: 10.1089/adt.2019.918
PMCID:
PMC6998042
ArticlePDF–511K
12.
Assays to Interrogate the Ability of Compounds to Inhibit the AF-2 or AF-1 Transactivation Domains of the Androgen Receptor
Ashley T. Fancher, Yun Hua, Christopher J. Strock, Paul A. Johnston
Assay Drug Dev Technol. November/December 2019; 17(8): 364–386. Published online 2019 Dec 13. doi: 10.1089/adt.2019.940
PMCID:
PMC6921095
ArticlePDF–1.6M
13.
High-Throughput Zika Viral Titer Assay for Rapid Screening of Antiviral Drugs
Emily M. Lee, Steven A. Titus, Miao Xu, Hengli Tang, Wei Zheng
Assay Drug Dev Technol. 2019 Apr 1; 17(3): 128–139. Published online 2019 Apr 8. doi: 10.1089/adt.2018.881
PMCID:
PMC6479255
ArticlePDF–1.6M
14.
High Content Screening Characterization of Head and Neck Squamous Cell Carcinoma Multicellular Tumor Spheroid Cultures Generated in 384-Well Ultra-Low Attachment Plates to Screen for Better Cancer Drug Leads
Stanton J. Kochanek, David A. Close, Paul A. Johnston
Assay Drug Dev Technol. 2019 Jan 1; 17(1): 17–36. Published online 2019 Jan 18. doi: 10.1089/adt.2018.896
PMCID:
PMC6352515
ArticlePDF–2.6M
15.
Macrophage Cytological Profiling and Anti-Inflammatory Drug Discovery
Tannia A. Lau, Walter M. Bray, R. Scott Lokey
Assay Drug Dev Technol. 2019 Jan 1; 17(1): 14–16. Published online 2019 Jan 18. doi: 10.1089/adt.2018.894
PMCID:
PMC6352509
ArticlePDF–127K
16.
High-Content Assay Multiplexing for Muscle Toxicity Screening in Human-Induced Pluripotent Stem Cell-Derived Skeletal Myoblasts
William D. Klaren, Ivan Rusyn
Assay Drug Dev Technol. 2018 Sep 1; 16(6): 333–342. Published online 2018 Sep 1. doi: 10.1089/adt.2018.860
PMCID:
PMC6114077
ArticlePDF–982K
17.
High-Content Screening Campaign to Identify Compounds That Inhibit or Disrupt Androgen Receptor-Transcriptional Intermediary Factor 2 Protein-Protein Interactions for the Treatment of Prostate Cancer
Ashley T. Fancher, Yun Hua, Daniel P. Camarco, David A. Close, Christopher J. Strock, Paul A. Johnston
Assay Drug Dev Technol. 2018 Aug 1; 16(6): 297–319. Published online 2018 Aug 1. doi: 10.1089/adt.2018.858
PMCID:
PMC6114076
ArticlePDF–2.2M
18.
A High-Throughput Time-Resolved Fluorescence Energy Transfer Assay to Screen for Modulators of RGS7/Gβ5/R7BP Complex
Brian S. Muntean, Dipak N. Patil, Franck Madoux, James Fossetta, Louis Scampavia, Timothy P. Spicer, Kirill A. Martemyanov
Assay Drug Dev Technol. 2018 Apr 1; 16(3): 150–161. Published online 2018 Apr 1. doi: 10.1089/adt.2017.839
PMCID:
PMC5906730
ArticlePDF–4.1M
19.
Development of a Time-Resolved Fluorescence Resonance Energy Transfer Ultrahigh-Throughput Screening Assay for Targeting the NSD3 and MYC Interaction
Jinglin Xiong, Valentina Gonzalez Pecchi, Min Qui, Andrey A. Ivanov, Xiulei Mo, Qiankun Niu, Xiang Chen, Haian Fu, Yuhong Du
Assay Drug Dev Technol. 2018 Mar 1; 16(2): 96–106. Published online 2018 Mar 1. doi: 10.1089/adt.2017.835
PMCID:
PMC5865254
ArticlePDF–611K
20.
FLECS Technology for High-Throughput Single-Cell Force Biology and Screening
Ivan Pushkarsky
Assay Drug Dev Technol. 2018 Jan 1; 16(1): 7–11. Published online 2018 Jan 1. doi: 10.1089/adt.2017.825
PMCID:
PMC5775112
ArticlePDF–393K

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