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Select item 41405651.

Biochemical analysis of pathogenic ligand-dependent FGFR2 mutations suggests distinct pathophysiological mechanisms for craniofacial and limb abnormalities

Omar A. Ibrahimi, Fuming Zhang, Anna V. Eliseenkova, Nobuyuki Itoh, Robert J. Linhardt, Moosa Mohammadi

Hum Mol Genet. Author manuscript; available in PMC 2014 Aug 21.

Published in final edited form as: Hum Mol Genet. 2004 Oct 1; 13(19): 2313–2324. Published online 2004 Jul 28. doi: 10.1093/hmg/ddh235

PMCID:: PMC4140565

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Select item 28715952.

Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes

PM Pollock, MG Gartside, LC Dejeza, MA Powell, MA Mallon, Cancer Genome Project, H Davies, M Mohammadi, PA Futreal, MR Stratton, JM Trent, PJ Goodfellow

Oncogene. Author manuscript; available in PMC 2010 May 17.

Published in final edited form as: Oncogene. 2007 Nov 1; 26(50): 7158–7162. Published online 2007 May 21. doi: 10.1038/sj.onc.1210529

PMCID:: PMC2871595

Article PDF–92K

Select item 28525183.

Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets

Nicholas Turner, Maryou B Lambros, Hugo M. Horlings, Alex Pearson, Rachel Sharpe, Rachael Natrajan, Felipe C Geyer, Marieke van Kouwenhove, Bas Kreike, Alan Mackay, Alan Ashworth, Marc J van de Vijver, Jorge S Reis-Filho

Oncogene. Author manuscript; available in PMC 2010 Oct 8.

Published in final edited form as: Oncogene. 2010 Apr 8; 29(14): 2013–2023. Published online 2010 Jan 18. doi: 10.1038/onc.2009.489

PMCID:: PMC2852518

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Select item 26491124.

Aberrant Receptor Internalization and Enhanced FRS2-dependent Signaling Contribute to the Transforming Activity of the Fibroblast Growth Factor Receptor 2 IIIb C3 Isoform

Jiyoung Y. Cha, Savitri Maddileti, Natalia Mitin, T. Kendall Harden, Channing J. Der

J Biol Chem. 2009 Mar 6; 284(10): 6227–6240. doi: 10.1074/jbc.M803998200

PMCID:: PMC2649112

Article PDF–1.4M

Select item 24383915.

Drug-sensitive FGFR2 mutations in endometrial carcinoma

Amit Dutt, Helga B. Salvesen, Tzu-Hsiu Chen, Alex H. Ramos, Robert C. Onofrio, Charlie Hatton, Richard Nicoletti, Wendy Winckler, Rupinder Grewal, Megan Hanna, Nicolas Wyhs, Liuda Ziaugra, Daniel J. Richter, Jone Trovik, Ingeborg B. Engelsen, Ingunn M. Stefansson, Tim Fennell, Kristian Cibulskis, Michael C. Zody, Lars A. Akslen, Stacey Gabriel, Kwok-Kin Wong, William R. Sellers, Matthew Meyerson, Heidi Greulich

Proc Natl Acad Sci U S A. 2008 Jun 24; 105(25): 8713–8717. Published online 2008 Jun 13. doi: 10.1073/pnas.0803379105

PMCID:: PMC2438391

Article PDF–514K

Select item 20941286.

A ‘Molecular Brake’ in the Kinase Hinge Region Regulates the Activity of Receptor Tyrosine Kinases

Huaibin Chen, Jinghong Ma, Wanqing Li, Anna V. Eliseenkova, Chongfeng Xu, Thomas A. Neubert, W. Todd Miller, Moosa Mohammadi

Mol Cell. Author manuscript; available in PMC 2007 Nov 26.

Published in final edited form as: Mol Cell. 2007 Sep 7; 27(5): 717–730. doi: 10.1016/j.molcel.2007.06.028

PMCID:: PMC2094128

Article PDF–1.7M

Select item 225307.

Activating mutations in the extracellular domain of the fibroblast growth factor receptor 2 function by disruption of the disulfide bond in the third immunoglobulin-like domain

Scott C. Robertson, April N. Meyer, Kristen C. Hart, Brendan D. Galvin, Melanie K. Webster, Daniel J. Donoghue

Proc Natl Acad Sci U S A. 1998 Apr 14; 95(8): 4567–4572. doi: 10.1073/pnas.95.8.4567

PMCID:: PMC22530

Article PDF–324K

Select item 139198.

Characterization of fibroblast growth factor receptor 2 overexpression in the human breast cancer cell line SUM-52PE

Stacey L Tannheimer, Alnawaz Rehemtulla, Stephen P Ethier

Breast Cancer Res. 2000; 2(4): 311–320. Published online 2000 May 24. doi: 10.1186/bcr73

PMCID:: PMC13919

Article PDF–2.2M

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