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Select item 99749771.

Contributions of NR1H3 genetic polymorphisms to susceptibility and effects of narrowband UVB phototherapy to nonsegmental vitiligo

Meifeng Xu, Qiuyu Xu, Yan Liu, Xiaoli Li, Mei Wang, Wei Dong, Yuning Song, Shengxiang Xiao

Sci Rep. 2023; 13: 3384. Published online 2023 Feb 28. doi: 10.1038/s41598-023-30047-7

PMCID:: PMC9974977

Article PDF–1.2M

Select item 81661692.

LXR directly regulates glycosphingolipid synthesis and affects human CD4+ T cell function

Kirsty E. Waddington, George A. Robinson, Beatriz Rubio-Cuesta, Eden Chrifi-Alaoui, Sara Andreone, Kok-Siong Poon, Iveta Ivanova, Lucia Martin-Gutierrez, Dylan M. Owen, Elizabeth C. Jury, Inés Pineda-Torra

Proc Natl Acad Sci U S A. 2021 May 25; 118(21): e2017394118. Published online 2021 May 18. doi: 10.1073/pnas.2017394118

PMCID:: PMC8166169

Article PDF–2.4M

Select item 80622673.

Liver x receptor alpha drives chemoresistance in response to side-chain hydroxycholesterols in triple negative breast cancer

Samantha A. Hutchinson, Alex Websdale, Giorgia Cioccoloni, Hanne Røberg-Larsen, Priscilia Lianto, Baek Kim, Ailsa Rose, Chrysa Soteriou, Arindam Pramanik, Laura M. Wastall, Bethany J. Williams, Madeline A. Henn, Joy J. Chen, Liqian Ma, J. Bernadette Moore, Erik Nelson, Thomas A. Hughes, James L. Thorne

Oncogene. 2021; 40(16): 2872–2883. Published online 2021 Mar 19. doi: 10.1038/s41388-021-01720-w

PMCID:: PMC8062267

Article PDF–2.3M

Select item 70773584.

LXR Activation Induces a Proinflammatory Trained Innate Immunity-Phenotype in Human Monocytes

Yahya Sohrabi, Glenn V. H. Sonntag, Laura C. Braun, Sina M. M. Lagache, Marie Liebmann, Luisa Klotz, Rinesh Godfrey, Florian Kahles, Johannes Waltenberger, Hannes M. Findeisen

Front Immunol. 2020; 11: 353. Published online 2020 Mar 10. doi: 10.3389/fimmu.2020.00353

PMCID:: PMC7077358

Article PDF–5.4M

Select item 66205735.

Liver X receptor-α activation enhances cholesterol secretion in lactating mammary epithelium

Diego Y. Grinman, Valeria P. Careaga, Elizabeth A. Wellberg, María V. Dansey, Edith C. Kordon, Steven M. Anderson, Marta S. Maier, Gerardo Burton, Paul S. MacLean, Michael C. Rudolph, Adali Pecci

Am J Physiol Endocrinol Metab. 2019 Jun 1; 316(6): E1136–E1145. Published online 2019 Apr 19. doi: 10.1152/ajpendo.00548.2018

PMCID:: PMC6620573

Article

Select item 64218106.

The Liver X Receptor Is Upregulated in Monocyte-Derived Macrophages and Modulates Inflammatory Cytokines Based on LXRα Polymorphism

Hyoun-Ah Kim, Wook-Young Baek, Mi-Hwa Han, Ju-Yang Jung, Chang-Hee Suh

Mediators Inflamm. 2019; 2019: 6217548. Published online 2019 Feb 28. doi: 10.1155/2019/6217548

PMCID:: PMC6421810

Article PDF–2.6M

Select item 63777097.

LXRα promotes cell metastasis by regulating the NLRP3 inflammasome in renal cell carcinoma

KeShan Wang, TianBo Xu, HaiLong Ruan, HaiBing Xiao, Jingchong Liu, ZhengShuai Song, Qi Cao, Lin Bao, Di Liu, Cheng Wang, Gong Cheng, HuaGeng Liang, ZhaoHui Chen, HongMei Yang, Ke Chen, XiaoPing Zhang

Cell Death Dis. 2019 Mar; 10(3): 159. Published online 2019 Feb 15. doi: 10.1038/s41419-019-1345-3

PMCID:: PMC6377709

Article PDF–3.8M

Select item 52829558.

Fatty acid binding profile of the liver X receptor α

Shimpi Bedi, Genesis Victoria Hines, Valery V. Lozada-Fernandez, Camila de Jesus Piva, Alagammai Kaliappan, S. Dean Rider, Jr., Heather A. Hostetler

J Lipid Res. 2017 Feb; 58(2): 393–402. Published online 2017 Jan 31. doi: 10.1194/jlr.M072447

PMCID:: PMC5282955

Article PDF–1.4M

Select item 50921549.

Nuclear receptor NR1H3 in familial multiple sclerosis

Zhe Wang, A. Dessa Sadovnick, Anthony L. Traboulsee, Jay P. Ross, Cecily Q. Bernales, Mary Encarnacion, Irene M. Yee, Madonna de Lemos, Talitha Greenwood, Joshua D. Lee, Galen Wright, Colin J. Ross, Si Zhang, Weihong Song, Carles Vilariño-Güell

Neuron. Author manuscript; available in PMC 2016 Nov 2.

Published in final edited form as: Neuron. 2016 Jun 1; 90(5): 948–954. doi: 10.1016/j.neuron.2016.04.039

PMCID:: PMC5092154

Article PDF–1.0M

Select item 481573110.

The anti-inflammatory effects of platelet-derived microparticles in human plasmacytoid dendritic cells involve liver X receptor activation

Adam Ceroi, Fanny Angelot Delettre, Charline Marotel, Thierry Gauthier, Afag Asgarova, Sabéha Biichlé, Anne Duperrier, Guillaume Mourey, Sylvain Perruche, Laurent Lagrost, David Masson, Philippe Saas

Haematologica. 2016 Mar; 101(3): e72–e76. doi: 10.3324/haematol.2015.135459

PMCID:: PMC4815731

Article PDF–1021K

Select item 478686111.

YiXin-Shu, a ShengMai-San-based traditional Chinese medicine formula, attenuates myocardial ischemia/reperfusion injury by suppressing mitochondrial mediated apoptosis and upregulating liver-X-receptor α

Yichao Zhao, Longwei Xu, Zhiqing Qiao, Lingchen Gao, Song Ding, Xiaoying Ying, Yuanyuan Su, Nan Lin, Ben He, Jun Pu

Sci Rep. 2016; 6: 23025. Published online 2016 Mar 11. doi: 10.1038/srep23025

PMCID:: PMC4786861

Article PDF–2.2M

Select item 456723512.

Anthocyanins inhibit high-glucose-induced cholesterol accumulation and inflammation by activating LXRα pathway in HK-2 cells

Chunyang Du, Yonghong Shi, Yunzhuo Ren, Haijiang Wu, Fang Yao, Jinying Wei, Ming Wu, Yanjuan Hou, Huijun Duan

Drug Des Devel Ther. 2015; 9: 5099–5113. Published online 2015 Sep 4. doi: 10.2147/DDDT.S90201

PMCID:: PMC4567235

Article PDF–2.0M

Select item 444091813.

The influence of ligand-activated LXR on primary human trophoblasts

Jacob C. Larkin, Sarah B. Sears, Yoel Sadovsky

Placenta. Author manuscript; available in PMC 2015 Nov 1.

Published in final edited form as: Placenta. 2014 Nov; 35(11): 919–924. Published online 2014 Sep 10. doi: 10.1016/j.placenta.2014.09.002

PMCID:: PMC4440918

Article PDF–776K

Select item 410762414.

Cholesterol efflux is LXRα isoform-dependent in human macrophages

A Zhi Sha Ma, Zhi Yuan Song, Qian Zhang

BMC Cardiovasc Disord. 2014; 14: 80. Published online 2014 Jul 4. doi: 10.1186/1471-2261-14-80

PMCID:: PMC4107624

Article PDF–601K

Select item 409557115.

Liver X receptors alpha gene (NR1H3) promoter polymorphisms are associated with systemic lupus erythematosus in Koreans

Ja-Young Jeon, Jin-Young Nam, Hyoun-Ah Kim, Yong-Beom Park, Sang-Cheol Bae, Chang-Hee Suh

Arthritis Res Ther. 2014; 16(3): R112. Published online 2014 May 14. doi: 10.1186/ar4563

PMCID:: PMC4095571

Article PDF–1.8M

Select item 398923116.

Liver X receptor activation stimulates iron export in human alternative macrophages

Gael Bories, Sophie Colin, Jonathan Vanhoutte, Bruno Derudas, Corinne Copin, Melanie Fanchon, Mehdi Daoudi, Loic Belloy, Stephan Haulon, Christophe Zawadzki, Brigitte Jude, Bart Staels, Giulia Chinetti-Gbaguidi

Circ Res. Author manuscript;

Published in final edited form as: Circ Res. 2013 Nov; 113(11): 1196–1205. Published online 2013 Sep 13. doi: 10.1161/CIRCRESAHA.113.301656

PMCID:: PMC3989231

Article

Select item 397596317.

Association of liver X receptor α (LXRα) gene polymorphism and coronary heart disease, serum lipids and glucose levels

Yun-Fei Zhou, Jing Zhang, Zong-Xue Li, Jing-Li Miao, Qiao-Xiang Yin, Jun-JIE Li, Xiao-Yan Zhang, Yuan-Yuan Li, Hui-Lan Luo

Lipids Health Dis. 2014; 13: 34. Published online 2014 Feb 17. doi: 10.1186/1476-511X-13-34

PMCID:: PMC3975963

Article PDF–164K

Select item 385299018.

The role of the liver X receptor in chronic obstructive pulmonary disease

Andrew Higham, Simon Lea, Jonathan Plumb, Barbara Maschera, Karen Simpson, David Ray, Dave Singh

Respir Res. 2013; 14(1): 106. Published online 2013 Oct 12. doi: 10.1186/1465-9921-14-106

PMCID:: PMC3852990

Article PDF–1.6M

Select item 383541019.

Effects of NR1H3 Genetic Variation on the Expression of Liver X Receptor α and the Progression of Alzheimer's Disease

Teemu Natunen, Henna Martiskainen, Timo Sarajärvi, Seppo Helisalmi, Juha-Pekka Pursiheimo, Jayashree Viswanathan, Marjo Laitinen, Petra Mäkinen, Tarja Kauppinen, Tuomas Rauramaa, Ville Leinonen, Irina Alafuzoff, Annakaisa Haapasalo, Hilkka Soininen, Mikko Hiltunen

PLoS One. 2013; 8(11): e80700. Published online 2013 Nov 20. doi: 10.1371/journal.pone.0080700