PMC Links for Gene (Select 1027) - PMC

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Select item 110309021.

p27 and salivary cancer

Ofer Ben-Izhak, Sharon Akrish, Shlomit Gan, Rafael M. Nagler

Cancer Immunol Immunother. 2009 Mar; 58(3): 469–473. Published online 2008 Jul 29. doi: 10.1007/s00262-008-0547-9

PMCID:: PMC11030902

Abstract Article PDF–226K

Select item 105308512.

Large HBV Surface Protein-Induced Unfolded Protein Response Dynamically Regulates p27 Degradation in Hepatocellular Carcinoma Progression

Yixiao Guo, Jie Shao, Renyu Zhang, Mingwei Han, Lingmin Kong, Zekun Liu, Hao Li, Ding Wei, Meng Lu, Shuai Zhang, Cong Zhang, Haolin Wei, Zhinan Chen, Huijie Bian

Int J Mol Sci. 2023 Sep; 24(18): 13825. Published online 2023 Sep 7. doi: 10.3390/ijms241813825

PMCID:: PMC10530851

Abstract Article PDF–49M

Select item 93014153.

Contribution of Cyclin-dependent Kinase Inhibitor 1B Genotypes to Childhood Leukemia Risk

JEN-SHENG PEI, WEN-SHIN CHANG, PEI-CHEN HSU, CHAO-CHUN CHEN, YA-CHEN YANG, SHIH-WEI HSU, YUAN-NIAN HSU, YUN-CHI WANG, CHUNG-HSING WANG, CHIA-WEN TSAI, DA-TIAN BAU

In Vivo. 2022 Jul-Aug; 36(4): 1637–1642. Published online 2022 Jul 3. doi: 10.21873/invivo.12874

PMCID:: PMC9301415

Abstract Article PDF–115K

Select item 92823584.

MEN4, the MEN1 Mimicker: A Case Series of three Phenotypically Heterogenous Patients With Unique CDKN1B Mutations

Amanda Seabrook, Ayanthi Wijewardene, Sunita De Sousa, Tang Wong, Nisa Sheriff, Anthony J Gill, Rakesh Iyer, Michael Field, Catherine Luxford, Roderick Clifton-Bligh, Ann McCormack, Katherine Tucker

J Clin Endocrinol Metab. 2022 Aug; 107(8): 2339–2349. Published online 2022 Mar 22. doi: 10.1210/clinem/dgac162

PMCID:: PMC9282358

Abstract Article

Select item 89596485.

Case Report: New CDKN1B Mutation in Multiple Endocrine Neoplasia Type 4 and Brief Literature Review on Clinical Management

Elisabetta Lavezzi, Alessandro Brunetti, Valeria Smiroldo, Gennaro Nappo, Vittorio Pedicini, Eleonora Vitali, Giampaolo Trivellin, Gherardo Mazziotti, Andrea Lania

Front Endocrinol (Lausanne) 2022; 13: 773143. Published online 2022 Mar 9. doi: 10.3389/fendo.2022.773143

PMCID:: PMC8959648

Abstract Article PDF–360K

Select item 85899266.

Lupus susceptibility region containing CDKN1B rs34330 mechanistically influences expression and function of multiple target genes, also linked to proliferation and apoptosis

Bhupinder Singh, Guru P. Maiti, Xujie Zhou, Mehdi Fazel-Najafabadi, Sang-Cheol Bae, Celi Sun, Chikashi Terao, Yukinori Okada, Kek Heng Chua, Yuta Kochi, Joel M. Guthridge, Hong Zhang, Matthew Weirauch, Judith A. James, John B. Harley, Gaurav K. Varshney, Loren L. Looger, Swapan K. Nath

Arthritis Rheumatol. Author manuscript; available in PMC 2022 Dec 1.

Published in final edited form as: Arthritis Rheumatol. 2021 Dec; 73(12): 2303–2313. Published online 2021 Oct 29. doi: 10.1002/art.41799

PMCID:: PMC8589926

Abstract Article PDF–1.7M

Select item 82291807.

The AMPK/p27^Kip1 Pathway as a Novel Target to Promote Autophagy and Resilience in Aged Cells

Lauren K. McKay, James P. White

Cells. 2021 Jun; 10(6): 1430. Published online 2021 Jun 8. doi: 10.3390/cells10061430

PMCID:: PMC8229180

Abstract Article PDF–1.0M

Select item 80247368.

A cancer‐associated CDKN1B mutation induces p27 phosphorylation on a novel residue: a new mechanism for tumor suppressor loss‐of‐function

Debora Bencivenga, Emanuela Stampone, Arianna Aulitto, Annunziata Tramontano, Clementina Barone, Aide Negri, Domenico Roberti, Silverio Perrotta, Fulvio Della Ragione, Adriana Borriello

Mol Oncol. 2021 Apr; 15(4): 915–941. Published online 2021 Feb 6. doi: 10.1002/1878-0261.12881

PMCID:: PMC8024736

Abstract Article PDF–5.1M

Select item 78394359.

CDKN1B mutation and copy number variation are associated with tumor aggressiveness in luminal breast cancer

Davide Viotto, Francesca Russo, Ilaria Anania, Ilenia Segatto, Gian Luca Rampioni Vinciguerra, Alessandra Dall'Acqua, Riccardo Bomben, Tiziana Perin, Martina Cusan, Monica Schiappacassi, Lorenzo Gerratana, Sara D'Andrea, Francesca Citron, Filippo Vit, Lorena Musco, Maria Chiara Mattevi, Giorgia Mungo, Milena S Nicoloso, Maura Sonego, Samuele Massarut, Roberto Sorio, Luigi Barzan, Giovanni Franchin, Giorgio Giorda, Emilio Lucia, Sandro Sulfaro, Vittorio Giacomarra, Jerry Polesel, Federica Toffolutti, Vincenzo Canzonieri, Fabio Puglisi, Valter Gattei, Andrea Vecchione, Barbara Belletti, Gustavo Baldassarre

J Pathol. 2021 Feb; 253(2): 234–245. Published online 2020 Dec 4. doi: 10.1002/path.5584

PMCID:: PMC7839435

Abstract Article PDF–10M

Select item 726981310.

CDKN1B Deletions are Associated with Metastasis in African American Men with Clinically Localized, Surgically Treated Prostate Cancer

Farzana A. Faisal, Sanjana Murali, Harsimar B. Kaur, Thiago Vidotto, Liana B. Guedes, Daniela C. Salles, Vishal Kothari, Jeffrey J. Tosoian, Sumin Han, Daniel H. Hovelson, Kevin Hu, Daniel E. Spratt, Alexander S. Baras, Scott A. Tomlins, Edward M. Schaeffer, Tamara L. Lotan

Clin Cancer Res. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Clin Cancer Res. 2020 Jun 1; 26(11): 2595–2602. Published online 2020 Jan 22. doi: 10.1158/1078-0432.CCR-19-1669

PMCID:: PMC7269813

Abstract Article PDF–559K

Select item 719003111.

Germline CDKN1B Loss-of-Function Variants Cause Pediatric Cushing’s Disease With or Without an MEN4 Phenotype

Fanny Chasseloup, Nathan Pankratz, John Lane, Fabio R Faucz, Margaret F Keil, Prashant Chittiboina, Denise M Kay, Tara Hussein Tayeb, Constantine A Stratakis, James L Mills, Laura C Hernández-Ramírez

J Clin Endocrinol Metab. 2020 Jun; 105(6): 1983–2005. Published online 2020 Mar 31. doi: 10.1210/clinem/dgaa160

PMCID:: PMC7190031

Abstract Article

Select item 688537112.

Cell Cycle Regulator p27 Mediates Body Mass Index Effects in Ovarian Cancer in FIGO-stages I-II

INGIRIDUR SKIRNISDOTTIR, HELENA AKERUD, TOMAS SEIDAL, INGER SUNDSTROM-POROMAA

Cancer Genomics Proteomics. 2019 Nov-Dec; 16(6): 443–450. Published online 2019 Nov 3. doi: 10.21873/cgp.20148

PMCID:: PMC6885371

Abstract Article PDF–255K

Select item 663778813.

Clinical Features of Multiple Endocrine Neoplasia Type 4: Novel Pathogenic Variant and Review of Published Cases

Anja Frederiksen, Maria Rossing, Pernille Hermann, Charlotte Ejersted, Rajesh V Thakker, Morten Frost

J Clin Endocrinol Metab. 2019 Sep; 104(9): 3637–3646. Published online 2019 Apr 16. doi: 10.1210/jc.2019-00082

PMCID:: PMC6637788

Abstract Article

Select item 646788814.

p27/Kip1 functions as a tumor suppressor and oncoprotein in osteosarcoma

Arthur W. Currier, E. A. Kolb, Richard G. Gorlick, Michael E. Roth, Vidya Gopalakrishnan, Valerie B. Sampson

Sci Rep. 2019; 9: 6161. Published online 2019 Apr 16. doi: 10.1038/s41598-019-42450-0

PMCID:: PMC6467888

Abstract Article PDF–6.8M

Select item 645985715.

Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation

Maksym Tsytlonok, Hugo Sanabria, Yuefeng Wang, Suren Felekyan, Katherina Hemmen, Aaron H. Phillips, Mi-Kyung Yun, M. Brett Waddell, Cheon-Gil Park, Sivaraja Vaithiyalingam, Luigi Iconaru, Stephen W. White, Peter Tompa, Claus A. M. Seidel, Richard Kriwacki

Nat Commun. 2019; 10: 1676. Published online 2019 Apr 11. doi: 10.1038/s41467-019-09446-w