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Select item 106929011.

AMPKα1 negatively regulates osteoclastogenesis and mitigates pathological bone loss

Mariana S.P. Ribeiro, Lucas G.R. Venturini, Cesar A. Speck-Hernandez, Paulo V.G. Alabarse, Thais Xavier, Thaise M. Taira, Letícia F. Duffles, Fernando Q. Cunha, Sandra Y. Fukada

J Biol Chem. 2023 Dec; 299(12): 105379. Published online 2023 Oct 21. doi: 10.1016/j.jbc.2023.105379

PMCID:: PMC10692901

Abstract Article PDF–2.5M

Select item 105426162.

Constitutively activated AMPKα1 protects against skeletal aging in mice by promoting bone‐derived IGF‐1 secretion

Yiqi Yang, Kai Yuan, Yihao Liu, Qishan Wang, Yixuan Lin, Shengbing Yang, Kai Huang, Tianyou Kan, Yuxin Zhang, Mingming Xu, Zhifeng Yu, Qiming Fan, Yugang Wang, Hanjun Li, Tingting Tang

Cell Prolif. 2023 Oct; 56(10): e13476. Published online 2023 Apr 11. doi: 10.1111/cpr.13476

PMCID:: PMC10542616

Abstract Article PDF–15M

Select item 98905343.

AMPK regulates homeostasis of invasion and viability in trophoblasts by redirecting glucose metabolism: Implications for pre‐eclampsia

Ping Xu, Yangxi Zheng, Jiujiang Liao, Mingyu Hu, Yike Yang, Baozhen Zhang, Mark D. Kilby, Huijia Fu, Yamin Liu, Fumei Zhang, Liling Xiong, Xiyao Liu, Huili Jin, Yue Wu, Jiayu Huang, Tingli Han, Li Wen, Rufei Gao, Yong Fu, Xiujun Fan, Hongbo Qi, Philip N. Baker, Chao Tong

Cell Prolif. 2023 Feb; 56(2): e13358. Published online 2022 Dec 8. doi: 10.1111/cpr.13358

PMCID:: PMC9890534

Abstract Article PDF–14M

Select item 98428654.

AMPK integrates metabolite and kinase-based immunometabolic control in macrophages

Iain R. Phair, Raid B. Nisr, Andrew J.M. Howden, Magdalena Sovakova, Noor Alqurashi, Marc Foretz, Douglas Lamont, Benoit Viollet, Graham Rena

Mol Metab. 2023 Feb; 68: 101661. Published online 2022 Dec 28. doi: 10.1016/j.molmet.2022.101661

PMCID:: PMC9842865

Abstract Article PDF–3.1M

Select item 98136815.

Manassantin B attenuates obesity by inhibiting adipogenesis and lipogenesis in an AMPK dependent manner

Jie Cai, Gu Qiong, Chanjuan Li, Lulu Sun, Yuhong Luo, Shengheng Yuan, Frank J. Gonzalez, Jun Xu

FASEB J. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: FASEB J. 2021 May; 35(5): e21496. doi: 10.1096/fj.202002126RR

PMCID:: PMC9813681

Abstract Article PDF–2.3M

Select item 97476326.

Glucagon changes substrate preference in gluconeogenesis

Huiting Xu, Yujue Wang, Hyokjoon Kwon, Ankit Shah, Katarzyna Kalemba, Xiaoyang Su, Ling He, Fredric E. Wondisford

J Biol Chem. 2022 Dec; 298(12): 102708. Published online 2022 Nov 17. doi: 10.1016/j.jbc.2022.102708

PMCID:: PMC9747632

Abstract Article PDF–1.1M

Select item 91120627.

Endothelial AMPKα1/PRKAA1 exacerbates inflammation in HFD‐fed mice

Qiuhua Yang, Qian Ma, Jiean Xu, Zhiping Liu, Xiaoxiao Mao, Yaqi Zhou, Yongfeng Cai, Qingen Da, Mei Hong, Neal L. Weintraub, David J. Fulton, Eric J. Belin de Chantemèle, Yuqing Huo

Br J Pharmacol. 2022 Apr; 179(8): 1661–1678. Published online 2021 Dec 27. doi: 10.1111/bph.15742

PMCID:: PMC9112062

Abstract Article PDF–30M

Select item 87446138.

The Energy Sensor AMPKα1 Is Critical in Rapamycin-Inhibition of mTORC1-S6K-Induced T-cell Memory

Anjuman Ara, Aizhang Xu, Khawaja Ashfaque Ahmed, Scot C. Leary, Md. Fahmid Islam, Zhaojia Wu, Rajni Chibbar, Jim Xiang

Int J Mol Sci. 2022 Jan; 23(1): 37. Published online 2021 Dec 21. doi: 10.3390/ijms23010037

PMCID:: PMC8744613

Abstract Article PDF–47M

Select item 84689199.

Deficiency of AMPKα1 Exacerbates Intestinal Injury and Remote Acute Lung Injury in Mesenteric Ischemia and Reperfusion in Mice

Hannah V. Hayes, Vivian Wolfe, Michael O’Connor, Nick C. Levinsky, Giovanna Piraino, Basilia Zingarelli

Int J Mol Sci. 2021 Sep; 22(18): 9911. Published online 2021 Sep 14. doi: 10.3390/ijms22189911

PMCID:: PMC8468919

Abstract Article PDF–1.6M

Select item 808295210.

Activating AMP-activated Protein Kinase Mediates Fibroblast Growth Factor 1 Protection from Nonalcoholic Fatty Liver Disease in Mice

Qian Lin, Zhifeng Huang, Genxiang Cai, Xia Fan, Xiaoqing Yan, Zhengshuai Liu, Zehua Zhao, Jingya Li, Jia Li, Hongxue Shi, Maiying Kong, Ming-Hua Zheng, Daniel J. Conklin, Paul N. Epstein, Kupper A. Wintergerst, Moosa Mohammadi, Lu Cai, Xiaokun Li, Yu Li, Yi Tan

Hepatology. Author manuscript; available in PMC 2021 Jun 22.

Published in final edited form as: Hepatology. 2021 Jun; 73(6): 2206–2222. doi: 10.1002/hep.31568

PMCID:: PMC8082952

Abstract Article PDF–4.0M

Select item 788185611.

A High-Fat Diet Attenuates AMPK α1 in Adipocytes to Induce Exosome Shedding and Nonalcoholic Fatty Liver Development In Vivo

Chenghui Yan, Xiaoxiang Tian, Jiayin Li, Dan Liu, Ding Ye, Zhonglin Xie, Yaling Han, Ming-Hui Zou

Diabetes. 2021 Feb; 70(2): 577–588. Published online 2020 Dec 1. doi: 10.2337/db20-0146

Correction in:: Diabetes. 2021 Sep; 70(9): 2160.

Correction in:: Diabetes. 2023 Jul; 72(7): 1035.

PMCID:: PMC7881856

Abstract Article PDF–14M

Select item 773006412.

Foam Cell Induction Activates AMPK But Uncouples Its Regulation of Autophagy and Lysosomal Homeostasis

Nicholas D. LeBlond, Julia R. C. Nunes, Tyler K. T. Smith, Conor O’Dwyer, Sabrina Robichaud, Suresh Gadde, Marceline Côté, Bruce E. Kemp, Mireille Ouimet, Morgan D. Fullerton

Int J Mol Sci. 2020 Dec; 21(23): 9033. Published online 2020 Nov 27. doi: 10.3390/ijms21239033

PMCID:: PMC7730064

Abstract Article PDF–4.3M

Select item 735371213.

Prion peptide-mediated calcium level alteration governs neuronal cell damage through AMPK-autophagy flux

Ji-Hong Moon, Sang-Youel Park

Cell Commun Signal. 2020; 18: 109. Published online 2020 Jul 11. doi: 10.1186/s12964-020-00590-1

PMCID:: PMC7353712

Abstract Article PDF–2.0M

Select item 721611314.

Loss of AMPKalpha1 Triggers Centrosome Amplification via PLK4 Upregulation in Mouse Embryonic Fibroblasts

Qiang Zhao, Kathleen A Coughlan, Ming-Hui Zou, Ping Song

Int J Mol Sci. 2020 Apr; 21(8): 2772. Published online 2020 Apr 16. doi: 10.3390/ijms21082772

PMCID:: PMC7216113

Abstract Article PDF–2.0M

Select item 720250315.

Inhibition of stearoyl-coenzyme A desaturase 1 ameliorates hepatic steatosis by inducing AMPK-mediated lipophagy

Youping Zhou, Li Zhong, Shengjie Yu, Wei Shen, Can Cai, Huihong Yu

Aging (Albany NY) 2020 Apr 30; 12(8): 7350–7362. Published online 2020 Apr 23. doi: 10.18632/aging.103082

PMCID:: PMC7202503

Abstract Article PDF–1.7M

Select item 645590016.

α1AMPK deletion in myelomonocytic cells induces a pro-inflammatory phenotype and enhances angiotensin II-induced vascular dysfunction

Thomas Jansen, Swenja Kröller-Schön, Tanja Schönfelder, Marc Foretz, Benoit Viollet, Andreas Daiber, Matthias Oelze, Moritz Brandt, Sebastian Steven, Miroslava Kvandová, Sanela Kalinovic, Jeremy Lagrange, John F Keaney, Jr, Thomas Münzel, Philip Wenzel, Eberhard Schulz

Cardiovasc Res. 2018 Dec 1; 114(14): 1883–1893. Published online 2018 Jul 4. doi: 10.1093/cvr/cvy172

PMCID:: PMC6455900

Abstract Article PDF–1.0M

Select item 581217217.

High Fat Diet Attenuates the Anticontractile Activity of Aortic PVAT via a Mechanism Involving AMPK and Reduced Adiponectin Secretion

Tarek A. M. Almabrouk, Anna D. White, Azizah B. Ugusman, Dominik S. Skiba, Omar J. Katwan, Husam Alganga, Tomasz J. Guzik, Rhian M. Touyz, Ian P. Salt, Simon Kennedy

Front Physiol. 2018; 9: 51. Published online 2018 Feb 9. doi: 10.3389/fphys.2018.00051