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Select item 69530301.

The Host Factor Erlin-1 is Required for Efficient Hepatitis C Virus Infection

Christina Whitten-Bauer, Josan Chung, Andoni Gómez-Moreno, Pilar Gomollón-Zueco, Michael D. Huber, Larry Gerace, Urtzi Garaigorta

Cells. 2019 Dec; 8(12): 1555. Published online 2019 Dec 2. doi: 10.3390/cells8121555

PMCID:: PMC6953030

Article PDF–5.5M

Select item 84705932.

Role of ERLINs in the Control of Cell Fate through Lipid Rafts

Valeria Manganelli, Agostina Longo, Vincenzo Mattei, Serena Recalchi, Gloria Riitano, Daniela Caissutti, Antonella Capozzi, Maurizio Sorice, Roberta Misasi, Tina Garofalo

Cells. 2021 Sep; 10(9): 2408. Published online 2021 Sep 13. doi: 10.3390/cells10092408

PMCID:: PMC8470593

Article PDF–1.2M

Select item 109146383.

Usp25-Erlin1/2 activity limits cholesterol flux to restrict virus infection

Qi Wen Teo, Ho Him Wong, Tiaan Heunis, Viktoriya Stancheva, Asmaa Hachim, Huibin Lv, Lewis Siu, Julian Ho, Yun Lan, Chris Ka Pun Mok, Rachel Ulferts, Sumana Sanyal

Dev Cell. 2023 Nov 20; 58(22): 2495–2509.e6. doi: 10.1016/j.devcel.2023.08.013

PMCID:: PMC10914638

Article PDF–6.0M

Select item 36407294.

The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study

Mary F. Feitosa, Mary K. Wojczynski, Kari E. North, Qunyuan Zhang, Michael A. Province, Jeffrey J. Carr, Ingrid B. Borecki

Atherosclerosis. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Atherosclerosis. 2013 May; 228(1): 175–180. Published online 2013 Feb 18. doi: 10.1016/j.atherosclerosis.2013.01.038

PMCID:: PMC3640729

Article PDF–581K

Select item 27648105.

SPFH1 and SPFH2 Mediate the Ubiquitination and Degradation of Inositol 1,4,5-Trisphosphate Receptors in Muscarinic Receptor-Expressing Hela Cells

Yuan Wang, Margaret M.P. Pearce, Danielle A. Sliter, James A. Olzmann, John C. Christianson, Ron R. Kopito, Stephanie Boeckmann, Christine Gagen, Gil S. Leichner, Joseph Roitelman, Richard J.H. Wojcikiewicz

Biochim Biophys Acta. Author manuscript; available in PMC 2010 Nov 1.

Published in final edited form as: Biochim Biophys Acta. 2009 Nov; 1793(11): 1710–1718. Published online 2009 Sep 12. doi: 10.1016/j.bbamcr.2009.09.004

PMCID:: PMC2764810

Article PDF–765K

Select item 74625496.

Disruption of the ERLIN–TM6SF2–APOB complex destabilizes APOB and contributes to non-alcoholic fatty liver disease

Bo-Tao Li, Ming Sun, Yun-Feng Li, Ju-Qiong Wang, Zi-Mu Zhou, Bao-Liang Song, Jie Luo

PLoS Genet. 2020 Aug; 16(8): e1008955. Published online 2020 Aug 10. doi: 10.1371/journal.pgen.1008955

PMCID:: PMC7462549

Article PDF–5.6M

Select item 91687157.

Binding of the erlin1/2 complex to the third intralumenal loop of IP₃R1 triggers its ubiquitin-proteasomal degradation

Xiaokong Gao, Caden G. Bonzerato, Richard J.H. Wojcikiewicz

J Biol Chem. 2022 Jun; 298(6): 102026. Published online 2022 May 11. doi: 10.1016/j.jbc.2022.102026

PMCID:: PMC9168715

Article PDF–4.4M

Select item 38064818.

Endoplasmic reticulum factor ERLIN2 regulates cytosolic lipid content in cancer cells

Guohui Wang, Xuebao Zhang, Jin-Sook Lee, Xiaogang Wang, Zeng-Quan Yang, Kezhong Zhang

Biochem J. Author manuscript; available in PMC 2013 Oct 23.

Published in final edited form as: Biochem J. 2012 Sep 15; 446(3): 415–425. doi: 10.1042/BJ20112050

PMCID:: PMC3806481

Article PDF–2.3M

Select item 26677309.

An Endoplasmic Reticulum (ER) Membrane Complex Composed of SPFH1 and SPFH2 Mediates the ER-associated Degradation of Inositol 1,4,5-Trisphosphate Receptors

Margaret M. P. Pearce, Duncan B. Wormer, Stephan Wilkens, Richard J. H. Wojcikiewicz

J Biol Chem. 2009 Apr 17; 284(16): 10433–10445. doi: 10.1074/jbc.M809801200

PMCID:: PMC2667730

Article PDF–1.1M

Select item 382401710.

Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis

Michael D. Huber, Paul W. Vesely, Kaustuv Datta, Larry Gerace

J Cell Biol. 2013 Nov 11; 203(3): 427–436. doi: 10.1083/jcb.201305076

PMCID:: PMC3824017

Article PDF–2.1M

Select item 415757211.

Exome Sequencing Links Corticospinal Motor Neuron Disease to Common Neurodegenerative Disorders

Gaia Novarino, Ali G. Fenstermaker, Maha S. Zaki, Matan Hofree, Jennifer L. Silhavy, Andrew D. Heiberg, Mostafa Abdellateef, Basak Rosti, Eric Scott, Lobna Mansour, Amira Masri, Hulya Kayserili, Jumana Y. Al-Aama, Ghada M. H. Abdel-Salam, Ariana Karminejad, Majdi Kara, Bulent Kara, Bita Bozorgmehri, Tawfeg Ben-Omran, Faezeh Mojahedi, Iman Gamal El Din Mahmoud, Naima Bouslam, Ahmed Bouhouche, Ali Benomar, Sylvain Hanein, Laure Raymond, Sylvie Forlani, Massimo Mascaro, Laila Selim, Nabil Shehata, Nasir Al-Allawi, P.S. Bindu, Matloob Azam, Murat Gunel, Ahmet Caglayan, Kaya Bilguvar, Aslihan Tolun, Mahmoud Y. Issa, Jana Schroth, Emily G. Spencer, Rasim O. Rosti, Naiara Akizu, Keith K. Vaux, Anide Johansen, Alice A. Koh, Hisham Megahed, Alexandra Durr, Alexis Brice, Giovanni Stevanin, Stacy B. Gabriel, Trey Ideker, Joseph G. Gleeson

Science. Author manuscript; available in PMC 2014 Sep 8.

Published in final edited form as: Science. 2014 Jan 31; 343(6170): 506–511. doi: 10.1126/science.1247363

PMCID:: PMC4157572

Article PDF–1.3M

Select item 256193712.

Population-Based Genome-wide Association Studies Reveal Six Loci Influencing Plasma Levels of Liver Enzymes

Xin Yuan, Dawn Waterworth, John R.B. Perry, Noha Lim, Kijoung Song, John C. Chambers, Weihua Zhang, Peter Vollenweider, Heide Stirnadel, Toby Johnson, Sven Bergmann, Noam D. Beckmann, Yun Li, Luigi Ferrucci, David Melzer, Dena Hernandez, Andrew Singleton, James Scott, Paul Elliott, Gerard Waeber, Lon Cardon, Timothy M. Frayling, Jaspal S. Kooner, Vincent Mooser

Am J Hum Genet. 2008 Oct 10; 83(4): 520–528. Published online 2008 Oct 3. doi: 10.1016/j.ajhg.2008.09.012

PMCID:: PMC2561937

Article PDF–572K

Select item 308320713.

Membrane-associated Ubiquitin Ligase Complex Containing gp78 Mediates Sterol-accelerated Degradation of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase

Youngah Jo, Peter V. Sguigna, Russell A. DeBose-Boyd

J Biol Chem. 2011 Apr 29; 286(17): 15022–15031. Published online 2011 Feb 22. doi: 10.1074/jbc.M110.211326

PMCID:: PMC3083207

Article PDF–1.4M

Select item 772476014.

Comparative multiplexed interactomics of SARS-CoV-2 and homologous coronavirus non-structural proteins identifies unique and shared host-cell dependencies

Jonathan P. Davies, Katherine M. Almasy, Eli F. McDonald, Lars Plate

ACS Infect Dis. Author manuscript; available in PMC 2024 Mar 5.

Published in final edited form as: ACS Infect Dis. 2020 Dec 11; 6(12): 3174–3189. Published online 2020 Dec 2. doi: 10.1021/acsinfecdis.0c00500

PMCID:: PMC7724760

Article PDF–2.1M

Select item 748243315.

Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex

Michael L. van de Weijer, Logesvaran Krshnan, Sabrina Liberatori, Elena Navarro Guerrero, Jacob Robson-Tull, Lilli Hahn, Robert Jan Lebbink, Emmanuel J.H.J. Wiertz, Roman Fischer, Daniel Ebner, Pedro Carvalho

Mol Cell. 2020 Sep 3; 79(5): 768–781.e7. doi: 10.1016/j.molcel.2020.07.009

Correction in:: Mol Cell. 2020 Oct 15; 80(2): 374–375.

PMCID:: PMC7482433

Article

Select item 244155216.

Blood Pressure Is Regulated by an α_1D-Adrenergic Receptor/Dystrophin Signalosome

John S. Lyssand, Mia C. DeFino, Xiao-bo Tang, Angie L. Hertz, David B. Feller, Jennifer L. Wacker, Marvin E. Adams, Chris Hague

J Biol Chem. 2008 Jul 4; 283(27): 18792–18800. doi: 10.1074/jbc.M801860200

PMCID:: PMC2441552

Article PDF–591K

Select item 652686817.

Neuropathy-causing mutations in HSPB1 impair autophagy by disturbing the formation of SQSTM1/p62 bodies

Mansour Haidar, Bob Asselbergh, Elias Adriaenssens, Vicky De Winter, Jean-Pierre Timmermans, Michaela Auer-Grumbach, Manisha Juneja, Vincent Timmerman

Autophagy. 2019; 15(6): 1051–1068. Published online 2019 Jan 31. doi: 10.1080/15548627.2019.1569930

PMCID:: PMC6526868

Article PDF–4.0M

Select item 381232418.

Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans

J L Del-Aguila, A L Beitelshees, R M Cooper-DeHoff, A B Chapman, J G Gums, K Bailey, Y Gong, S T Turner, J A Johnson, E Boerwinkle

Pharmacogenomics J. 2014 Feb; 14(1): 35–40. Published online 2013 Feb 12. doi: 10.1038/tpj.2013.3

PMCID:: PMC3812324

Article PDF–662K

Select item 603073019.

AP-SWATH Reveals Direct Involvement of VCP/p97 in Integrated Stress Response Signaling Through Facilitating CReP/PPP1R15B Degradation

Julia Hülsmann, Bojana Kravic, Matthias Weith, Matthias Gstaiger, Ruedi Aebersold, Ben C. Collins, Hemmo Meyer

Mol Cell Proteomics. 2018 Jul; 17(7): 1295–1307. Published online 2018 Mar 29. doi: 10.1074/mcp.RA117.000471

PMCID:: PMC6030730

Article PDF–3.8M

Select item 330886420.

Ubiquitin Ligase Substrate Identification through Quantitative Proteomics at Both the Protein and Peptide Levels

Kimberly A. Lee, Lisa P. Hammerle, Paul S. Andrews, Matthew P. Stokes, Tomas Mustelin, Jeffrey C. Silva, Roy A. Black, John R. Doedens

J Biol Chem. 2011 Dec 2; 286(48): 41530–41538. Published online 2011 Oct 10. doi: 10.1074/jbc.M111.248856

PMCID:: PMC3308864

Article PDF–815K

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