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Select item 77203341.

The Potential Role of CERS1 in Autophagy Through PI3K/AKT Signaling Pathway in Hypophysoma

Jingtao Wang, Jimin Zhang, Dongzhou Ma, Xiushan Li

Technol Cancer Res Treat. 2020; 19: 1533033820977536. Published online 2020 Dec 3. doi: 10.1177/1533033820977536

PMCID:: PMC7720334

Article PDF–1.0M

Select item 109543062.

Inhibition of CERS1 in skeletal muscle exacerbates age-related muscle dysfunction

Martin Wohlwend, Pirkka-Pekka Laurila, Ludger JE Goeminne, Tanes Lima, Ioanna Daskalaki, Xiaoxu Li, Giacomo von Alvensleben, Barbara Crisol, Renata Mangione, Hector Gallart-Ayala, Olivier Burri, Stephen Butler, Jonathan Morris, Nigel Turner, Julijana Ivanisevic, Johan Auwerx

eLife. 2024; 12: RP90522. Published online 2024 Mar 20. doi: 10.7554/eLife.90522

PMCID:: PMC10954306

Article PDF–3.8M

Select item 49936683.

Programmed cell death genes are linked to elevated creatine kinase levels in unhealthy male nonagenarians

Sangkyu Kim, Eric Simon, Leann Myers, L. Lee Hamm, S. Michal Jazwinski

Gerontology. Author manuscript; available in PMC 2017 Feb 26.

Published in final edited form as: Gerontology. 2016; 62(5): 519–529. Published online 2016 Feb 26. doi: 10.1159/000443793

PMCID:: PMC4993668

Article PDF–1.0M

Select item 36895834.

Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy

R. David Sentelle, Can E. Senkal, Wenhui Jiang, Suriyan Ponnusamy, Salih Gencer, Shanmugam Panneer Selvam, Venkat K. Ramshesh, Yuri K. Peterson, John J. Lemasters, Zdzislaw M. Szulc, Jacek Bielawski, Besim Ogretmen

Nat Chem Biol. Author manuscript; available in PMC 2013 Jun 21.

Published in final edited form as: Nat Chem Biol. 2012 Oct; 8(10): 831–838. doi: 10.1038/nchembio.1059

Correction in:: volume 8 on page 1008

PMCID:: PMC3689583

Article PDF–1.3M

Select item 33768375.

Concerted functions of HDAC1 and microRNA-574-5p repress alternatively spliced ceramide synthase 1 expression in human cancer cells

Marisa Meyers-Needham, Suriyan Ponnusamy, Salih Gencer, Wenhui Jiang, Raquela J Thomas, Can E Senkal, Besim Ogretmen

EMBO Mol Med. 2012 Feb; 4(2): 78–92. doi: 10.1002/emmm.201100189

PMCID:: PMC3376837

Article PDF–1.1M

Select item 29415586.

HRAS1 and LASS1 with APOE are associated with human longevity and healthy aging

S. Michal Jazwinski, Sangkyu Kim, Jianliang Dai, Li Li, Xiuhua Bi, James C. Jiang, Jonathan Arnold, Mark A. Batzer, Jerilyn A. Walker, David A. Welsh, Christina M. Lefante, Julia Volaufova, Leann Myers, L. Joseph Su, Dorothy B. Hausman, Michael V. Miceli, Eric Ravussin, Leonard W. Poon, Katie E. Cherry, Michael A. Welsch, Georgia Centenarian Study and the Louisiana Healthy Aging Study

Aging Cell. Author manuscript; available in PMC 2011 Oct 1.

Published in final edited form as: Aging Cell. 2010 Oct; 9(5): 698–708. Published online 2010 Aug 4. doi: 10.1111/j.1474-9726.2010.00600.x

PMCID:: PMC2941558

Article PDF–583K

Select item 27915117.

Stress-induced ER to Golgi translocation of ceramide synthase 1 is dependent on proteasomal processing

Priya Sridevi, Hannah Alexander, Elad L. Laviad, Junxia Min, Adi Mesika, Mark Hannink, Anthony H. Futerman, Stephen Alexander

Exp Cell Res. Author manuscript; available in PMC 2011 Jan 1.

Published in final edited form as: Exp Cell Res. 2010 Jan 1; 316(1): 78–91. Published online 2009 Oct 2. doi: 10.1016/j.yexcr.2009.09.027

PMCID:: PMC2791511

Article PDF–5.5M

Select item 516368.

Expression of growth/differentiation factor 1 in the nervous system: conservation of a bicistronic structure.

S J Lee

Proc Natl Acad Sci U S A. 1991 May 15; 88(10): 4250–4254. doi: 10.1073/pnas.88.10.4250

PMCID:: PMC51636

Summary Page Browse PDF–1.6M

Select item 11845809.

Mammalian Lass6 and its related family members regulate synthesis of specific ceramides

Yukiko Mizutani, Akio Kihara, Yasuyuki Igarashi

Biochem J. 2005 Aug 15; 390(Pt 1): 263–271. Prepublished online 2005 Apr 11. Published online 2005 Aug 9. doi: 10.1042/BJ20050291

PMCID:: PMC1184580

Article PDF–642K

Select item 886447210.

Interactome Analysis of Human Phospholipase D and Phosphatidic Acid-Associated Protein Network

Rebecca Elizabeth Kattan, Han Han, Gayoung Seo, Bing Yang, Yongqi Lin, Max Dotson, Stephanie Pham, Yahya Menely, Wenqi Wang

Mol Cell Proteomics. 2022 Feb; 21(2): 100195. Published online 2022 Jan 8. doi: 10.1016/j.mcpro.2022.100195

PMCID:: PMC8864472

Article PDF–3.6M

Select item 823607811.

Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs

Katherine M. Almasy, Jonathan P. Davies, Lars Plate

Mol Cell Proteomics. 2021; 20: 100120. Published online 2021 Jun 27. doi: 10.1016/j.mcpro.2021.100120

PMCID:: PMC8236078

Article PDF–4.6M

Select item 655126612.

FAM105A/OTULINL is a pseudodebuiquitinase of the OTU-class that localizes to the ER membrane

Derek F. Ceccarelli, Sofiia Ivantsiv, Amber Anne Mullin, Etienne Coyaud, Noah Manczyk, Pierre Maisonneuve, Igor Kurinov, Liang Zhao, Chris Go, Anne-Claude Gingras, Brian Raught, Sabine Cordes, Frank Sicheri

Structure. Author manuscript; available in PMC 2020 Jun 4.

Published in final edited form as: Structure. 2019 Jun 4; 27(6): 1000–1012.e6. Published online 2019 May 2. doi: 10.1016/j.str.2019.03.022

PMCID:: PMC6551266

Article PDF–3.4M

Select item 537173013.

Systematic protein–protein interaction mapping for clinically relevant human GPCRs

Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar

Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430

PMCID:: PMC5371730

Article PDF–4.1M

Select item 895155614.

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins

Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux

Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611

PMCID:: PMC8951556

Article PDF–4.4M

Select item 720679315.

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling

Jin Huk Choi, Xue Zhong, William McAlpine, Tzu-Chieh Liao, Duanwu Zhang, Beibei Fang, Jamie Russell, Sara Ludwig, Evan Nair-Gill, Zhao Zhang, Kuan-wen Wang, Takuma Misawa, Xiaoming Zhan, Mihwa Choi, Tao Wang, Xiaohong Li, Miao Tang, Qihua Sun, Liyang Yu, Anne R. Murray, Eva Marie Y. Moresco, Bruce Beutler

Science. Author manuscript; available in PMC 2020 May 8.

Published in final edited form as: Science. 2019 May 10; 364(6440): eaau0812. doi: 10.1126/science.aau0812

PMCID:: PMC7206793

Article PDF–2.2M

Select item 923162316.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Article PDF–6.0M

Select item 508937417.

A dynamic protein interaction landscape of the human centrosome-cilium interface

Gagan D. Gupta, Étienne Coyaud, João Gonçalves, Bahareh A. Mojarad, Yi Liu, Qianzhu Wu, Ladan Gheiratmand, David Comartin, Johnny M. Tkach, Sally W.T. Cheung, Mikhail Bashkurov, Monica Hasegan, James D. Knight, Zhen-Yuan Lin, Markus Schueler, Friedhelm Hildebrandt, Jason Moffat, Anne-Claude Gingras, Brian Raught, Laurence Pelletier

Cell. Author manuscript; available in PMC 2016 Dec 3.

Published in final edited form as: Cell. 2015 Dec 3; 163(6): 1484–1499. doi: 10.1016/j.cell.2015.10.065

PMCID:: PMC5089374

Article PDF–1.5M

Select item 742732718.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Article

Select item 948193319.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Article PDF–3.5M

Select item 1023742220.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Article PDF–23M

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