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Select item 107835751.

Using CRISPR-Cas9/phosphoproteomics to identify substrates of calcium/calmodulin-dependent kinase 2δ

Euijung Park, Chin-Rang Yang, Viswanathan Raghuram, Lihe Chen, Chung-Lin Chou, Mark A. Knepper

J Biol Chem. 2023 Dec; 299(12): 105371. Published online 2023 Oct 20. doi: 10.1016/j.jbc.2023.105371

PMCID:: PMC10783575

Article PDF–2.7M

Select item 96434382.

Oxidative stress–induced autonomous activation of the calcium/calmodulin-dependent kinase II involves disulfide formation in the regulatory domain

Nathália Rocco-Machado, Lo Lai, Geumsoo Kim, Yi He, Elizabeth D. Luczak, Mark E. Anderson, Rodney L. Levine

J Biol Chem. 2022 Nov; 298(11): 102579. Published online 2022 Oct 8. doi: 10.1016/j.jbc.2022.102579

PMCID:: PMC9643438

Article PDF–2.1M

Select item 66143573.

Genetic deletion of calcium/calmodulin-dependent protein kinase type II delta does not mitigate adverse myocardial remodeling in volume-overloaded hearts

Belal A. Mohamed, Manar Elkenani, Joanna Jakubiczka-Smorag, Eric Buchholz, Sabrina Koszewa, Dawid Lbik, Moritz Schnelle, Gerd Hasenfuss, Karl Toischer

Sci Rep. 2019; 9: 9889. Published online 2019 Jul 8. doi: 10.1038/s41598-019-46332-3

PMCID:: PMC6614357

Article PDF–1.9M

Select item 58201124.

Improvement of Cardiomyocyte Function by a Novel Pyrimidine-Based CaMKII-Inhibitor

Stefan Neef, Alexander Steffens, Patricia Pellicena, Julian Mustroph, Simon Lebek, Katharina R. Ort, Howard Schulman, Lars S. Maier

J Mol Cell Cardiol. Author manuscript; available in PMC 2019 Feb 1.

Published in final edited form as: J Mol Cell Cardiol. 2018 Feb; 115: 73–81. Published online 2017 Dec 30. doi: 10.1016/j.yjmcc.2017.12.015

PMCID:: PMC5820112

Article PDF–1.2M

Select item 56326755.

Activity-Dependent Phosphorylation by CaMKIIδ Alters the Ca²⁺ Affinity of the Multi-C₂-Domain Protein Otoferlin

Sandra Meese, Andreia P. Cepeda, Felix Gahlen, Christopher M. Adams, Ralf Ficner, Anthony J. Ricci, Stefan Heller, Ellen Reisinger, Meike Herget

Front Synaptic Neurosci. 2017; 9: 13. Published online 2017 Oct 4. doi: 10.3389/fnsyn.2017.00013

PMCID:: PMC5632675

Article PDF–10M

Select item 55643006.

CaMKIIδ subtypes differentially regulate infarct formation following ex vivo myocardial ischemia/reperfusion through NF-κB and TNF-α

Charles B.B. Gray, Takeshi Suetomi, Sunny Xiang, Shikha Mishra, Erik A. Blackwood, Christopher C. Glembotski, Shigeki Miyamoto, B. Daan Westenbrink, Joan Heller Brown

J Mol Cell Cardiol. Author manuscript; available in PMC 2018 Feb 1.

Published in final edited form as: J Mol Cell Cardiol. 2017 Feb; 103: 48–55. Published online 2017 Jan 7. doi: 10.1016/j.yjmcc.2017.01.002

PMCID:: PMC5564300

Article PDF–1.0M

Select item 52140907.

Oxidized CaMKII promotes asthma through the activation of mast cells

Jingjing Qu, Danh C. Do, Yufeng Zhou, Elizabeth Luczak, Wayne Mitzner, Mark E. Anderson, Peisong Gao

JCI Insight. 2017 Jan 12; 2(1): e90139. Published online 2017 Jan 12. doi: 10.1172/jci.insight.90139

PMCID:: PMC5214090

Article PDF–2.9M

Select item 41335948.

Tubulin polymerization disrupts cardiac β-adrenergic regulation of late I_Na

Nataliya Dybkova, Stefan Wagner, Johannes Backs, Thomas J. Hund, Peter J. Mohler, Thomas Sowa, Viacheslav O. Nikolaev, Lars S. Maier

Cardiovasc Res. 2014 Jul 1; 103(1): 168–177. Published online 2014 May 8. doi: 10.1093/cvr/cvu120

PMCID:: PMC4133594

Article PDF–1.8M

Select item 39610809.

A novel computational model of mouse myocyte electrophysiology to assess the synergy between Na⁺ loading and CaMKII

S Morotti, A G Edwards, A D McCulloch, D M Bers, E Grandi

J Physiol. 2014 Mar 15; 592(Pt 6): 1181–1197. Published online 2014 Feb 12. doi: 10.1113/jphysiol.2013.266676

PMCID:: PMC3961080

Article PDF–1.9M

Select item 394855810.

Intracellular signalling mechanism responsible for modulation of sarcolemmal ATP-sensitive potassium channels by nitric oxide in ventricular cardiomyocytes

Dai-Min Zhang, Yongping Chai, Jeffrey R Erickson, Joan Heller Brown, Donald M Bers, Yu-Fung Lin

J Physiol. 2014 Mar 1; 592(Pt 5): 971–990. Published online 2014 Jan 8. doi: 10.1113/jphysiol.2013.264697

PMCID:: PMC3948558

Article PDF–3.8M

Select item 373851411.

The Multifunctional Ca²⁺/Calmodulin-Dependent Kinase IIδ (CaMKIIδ) Regulates Arteriogenesis in a Mouse Model of Flow-Mediated Remodeling

Jason A. Scott, Paula J. Klutho, Ramzi El Accaoui, Emily Nguyen, Ashlee N. Venema, Litao Xie, Shuxia Jiang, Megan Dibbern, Sabrina Scroggins, Anand M. Prasad, Elisabeth D. Luczak, Melissa K. Davis, Weiwei Li, Xiaoqun Guan, Johannes Backs, Annette J. Schlueter, Robert M. Weiss, Francis J. Miller, Mark E. Anderson, Isabella M. Grumbach

PLoS One. 2013; 8(8): e71550. Published online 2013 Aug 8. doi: 10.1371/journal.pone.0071550

PMCID:: PMC3738514

Article PDF–8.5M

Select item 361848612.

Stretch Current-induced Abnormal Impulses in CaMKIIδ Knockout Mouse Ventricular Myocytes

Dongwu Lai, Lin Xu, Jun Cheng, Arnaud B. Guilbert, Hyun Joung Lim, Guosheng Fu, Yanggan Wang

J Cardiovasc Electrophysiol. Author manuscript; available in PMC 2014 Apr 1.

Published in final edited form as: J Cardiovasc Electrophysiol. 2013 Apr; 24(4): 457–463. Published online 2012 Dec 21. doi: 10.1111/jce.12060

PMCID:: PMC3618486

Article PDF–714K

Select item 336815113.

CaMKIIδ_C Slows [Ca]_i Decline in Cardiac Myocytes by Promoting Ca Sparks

Tao Guo, Tong Zhang, Kenneth S. Ginsburg, Shikha Mishra, Joan Heller Brown, Donald M. Bers

Biophys J. 2012 Jun 6; 102(11): 2461–2470. doi: 10.1016/j.bpj.2012.04.015

PMCID:: PMC3368151

Article PDF–674K

Select item 303290514.

Diastolic dysfunction and arrhythmias caused by overexpression of CaMKIIδ_C can be reversed by inhibition of late Na⁺ current

Samuel Sossalla, Ulrike Maurer, Hanna Schotola, Nico Hartmann, Michael Didié, Wolfram-H. Zimmermann, Claudius Jacobshagen, Stefan Wagner, Lars S. Maier

Basic Res Cardiol. 2011; 106(2): 263–272. Published online 2010 Dec 21. doi: 10.1007/s00395-010-0136-x

PMCID:: PMC3032905

Article PDF–501K

Select item 273410415.

Ca/Calmodulin Kinase II Differentially Modulates Potassium Currents

Stefan Wagner, Elena Hacker, Eleonora Grandi, Sarah L. Weber, Nataliya Dybkova, Samuel Sossalla, Thomas Sowa, Larissa Fabritz, Paulus Kirchhof, Donald M. Bers, Lars S. Maier

Circ Arrhythm Electrophysiol. Author manuscript; available in PMC 2010 Jun 1.

Published in final edited form as: Circ Arrhythm Electrophysiol. 2009 Jun; 2(3): 285–294. Published online 2009 Apr 17. doi: 10.1161/CIRCEP.108.842799

PMCID:: PMC2734104

Article PDF–2.9M

Select item 267387916.

Requirement for Ca²⁺/calmodulin–dependent kinase II in the transition from pressure overload–induced cardiac hypertrophy to heart failure in mice

Haiyun Ling, Tong Zhang, Laetitia Pereira, Christopher Kable Means, Hongqiang Cheng, Yusu Gu, Nancy D. Dalton, Kirk L. Peterson, Ju Chen, Donald Bers, Joan Heller Brown

J Clin Invest. 2009 May 1; 119(5): 1230–1240. Published online 2009 Apr 20. doi: 10.1172/JCI38022

Correction in:: J Clin Invest. 2012 Apr 2; 122(4): 1584.

PMCID:: PMC2673879

Article PDF–2.5M

Select item 265015817.

The δ isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload

Johannes Backs, Thea Backs, Stefan Neef, Michael M. Kreusser, Lorenz H. Lehmann, David M. Patrick, Chad E. Grueter, Xiaoxia Qi, James A. Richardson, Joseph A. Hill, Hugo A. Katus, Rhonda Bassel-Duby, Lars S. Maier, Eric N. Olson

Proc Natl Acad Sci U S A. 2009 Feb 17; 106(7): 2342–2347. Published online 2009 Jan 28. doi: 10.1073/pnas.0813013106