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Select item 34006061.

Cre-Mediated Stress Affects Sirtuin Expression Levels, Peroxisome Biogenesis and Metabolism, Antioxidant and Proinflammatory Signaling Pathways

Yu Xiao, Srikanth Karnati, Guofeng Qian, Anca Nenicu, Wei Fan, Svetlin Tchatalbachev, Anita Höland, Hamid Hossain, Florian Guillou, Georg H. Lüers, Eveline Baumgart-Vogt

PLoS One. 2012; 7(7): e41097. Published online 2012 Jul 19. doi: 10.1371/journal.pone.0041097

PMCID:: PMC3400606

Article PDF–1.8M

Select item 104735112.

Sertoli cell-enriched proteins in mouse and human testicular interstitial fluid

Liza O’Donnell, Laura F. Dagley, Michael Curley, Annalucia Darbey, Peter J. O’Shaughnessy, Thorsten Diemer, Adrian Pilatz, Daniela Fietz, Peter G. Stanton, Lee B. Smith, Diane Rebourcet

PLoS One. 2023; 18(9): e0290846. Published online 2023 Sep 1. doi: 10.1371/journal.pone.0290846

PMCID:: PMC10473511

Article PDF–1.9M

Select item 96639403.

Sertoli cells require TDP-43 to support spermatogenesis

Helena D Zomer, Hari Prasad Osuru, Apoorv Chebolu, Jeremy M Rayl, Madeline Timken, Prabhakara P Reddi

Biol Reprod. 2022 Nov; 107(5): 1345–1359. Published online 2022 Aug 20. doi: 10.1093/biolre/ioac165

PMCID:: PMC9663940

Article PDF–3.5M

Select item 93342844.

Connexin43 represents an important regulator for Sertoli cell morphology, Sertoli cell nuclear ultrastructure, and Sertoli cell maturation

Sarah Staggenborg, Rüdiger Koch, Kristina Rode, Hanna Hüneke, Louiza Tiedje, Gudrun Wirth, Marion Langeheine, Ines Blume, Kerstin Rohn, Christoph Wrede, Christiane Pfarrer, Ralph Brehm

Sci Rep. 2022; 12: 12898. Published online 2022 Jul 28. doi: 10.1038/s41598-022-16919-4

PMCID:: PMC9334284

Article PDF–2.3M

Select item 86344425.

Single-Cell RNA Sequencing Defines the Regulation of Spermatogenesis by Sertoli-Cell Androgen Signaling

Congcong Cao, Qian Ma, Shaomei Mo, Ge Shu, Qunlong Liu, Jing Ye, Yaoting Gui

Front Cell Dev Biol. 2021; 9: 763267. Published online 2021 Nov 15. doi: 10.3389/fcell.2021.763267

PMCID:: PMC8634442

Article PDF–19M

Select item 84765146.

Specific deletion of protein phosphatase 6 catalytic subunit in Sertoli cells leads to disruption of spermatogenesis

Wen-Long Lei, Yuan-Yuan Li, Tie-Gang Meng, Yan Ning, Si-Min Sun, Chun-Hui Zhang, Yaoting Gui, Zhen-Bo Wang, Wei-Ping Qian, Qing-Yuan Sun

Cell Death Dis. 2021 Oct; 12(10): 883. Published online 2021 Sep 27. doi: 10.1038/s41419-021-04172-y

PMCID:: PMC8476514

Article PDF–9.4M

Select item 78989037.

Sperm proteins and cancer‐testis antigens are released by the seminiferous tubules in mice and men

Liza O'Donnell, Diane Rebourcet, Laura F. Dagley, Raouda Sgaier, Giuseppe Infusini, Peter J. O'Shaughnessy, Frederic Chalmel, Daniela Fietz, Wolfgang Weidner, Julien M. D. Legrand, Robin M. Hobbs, Robert I. McLachlan, Andrew I. Webb, Adrian Pilatz, Thorsten Diemer, Lee B. Smith, Peter G. Stanton

FASEB J. 2021 Mar; 35(3): e21397. Published online 2021 Feb 10. doi: 10.1096/fj.202002484R

Correction in:: FASEB J. 2021 Jul; 35(7): e21635.

PMCID:: PMC7898903

Article PDF–1.4M

Select item 71406728.

Loss of Cx43 in Murine Sertoli Cells Leads to Altered Prepubertal Sertoli Cell Maturation and Impairment of the Mitosis-Meiosis Switch

Erika Hilbold, Ottmar Distl, Martina Hoedemaker, Sandra Wilkening, Rüdiger Behr, Aleksandar Rajkovic, Marion Langeheine, Kristina Rode, Klaus Jung, Julia Metzger, Ralph H. J. Brehm

Cells. 2020 Mar; 9(3): 676. Published online 2020 Mar 10. doi: 10.3390/cells9030676

PMCID:: PMC7140672

Article PDF–8.1M

Select item 66197649.

Relationship of transcriptional markers to Leydig cell number in the mouse testis

Diane Rebourcet, Ana Monteiro, Lyndsey Cruickshanks, Nathan Jeffery, Sarah Smith, Laura Milne, Peter J. O’Shaughnessy, Lee B. Smith

PLoS One. 2019; 14(7): e0219524. Published online 2019 Jul 10. doi: 10.1371/journal.pone.0219524

PMCID:: PMC6619764

Article PDF–2.6M

Select item 655440310.

The alteration of RhoA geranylgeranylation and Ras farnesylation breaks the integrity of the blood–testis barrier and results in hypospermatogenesis

Ruilou Zhu, Jiangnan Wang, Tianxiang Feng, Xuechun Hu, Chen Jiang, Xiuxing Wang, Kang Li, Yongjuan Sang, Yue Hua, Haixiang Sun, Bing Yao, Chaojun Li

Cell Death Dis. 2019 Jun; 10(6): 450. Published online 2019 Jun 6. doi: 10.1038/s41419-019-1688-9

PMCID:: PMC6554403

Article PDF–2.8M

Select item 647205111.

Androgen receptor expression is required to ensure development of adult Leydig cells and to prevent development of steroidogenic cells with adrenal characteristics in the mouse testis

Peter J. O’Shaughnessy, Rod T. Mitchell, Ana Monteiro, Laura O’Hara, Lyndsey Cruickshanks, Hedi Claahsen-van der Grinten, Pamela Brown, Margaret Abel, Lee B. Smith

BMC Dev Biol. 2019; 19: 8. Published online 2019 Apr 17. doi: 10.1186/s12861-019-0189-5

PMCID:: PMC6472051

Article PDF–9.7M

Select item 618783912.

The Glucocorticoid-Induced Leucine Zipper (GILZ) Is Essential for Spermatogonial Survival and Spermatogenesis

Y. Romero, M. Vuandaba, P. Suarez, C. Grey, P. Calvel, B. Conne, D. Pearce, B. de Massy, E. Hummler, S. Nef

Sex Dev. 2012 Jun; 6(4): 169–177. Published online 2012 May 10. doi: 10.1159/000338415

PMCID:: PMC6187839

Article

Select item 607047613.

Leukemia Inhibitory Factor-Receptor is Dispensable for Prenatal Testis Development but is Required in Sertoli cells for Normal Spermatogenesis in Mice

Michael Curley, Laura Milne, Sarah Smith, Nina Atanassova, Diane Rebourcet, Annalucia Darbey, Patrick W. F. Hadoke, Sara Wells, Lee B. Smith

Sci Rep. 2018; 8: 11532. Published online 2018 Aug 1. doi: 10.1038/s41598-018-30011-w

PMCID:: PMC6070476

Article PDF–6.6M

Select item 598341214.

Loss of connexin43 in murine Sertoli cells and its effect on blood-testis barrier formation and dynamics

Julia Hollenbach, Klaus Jung, Joanna Noelke, Hagen Gasse, Christiane Pfarrer, Mirja Koy, Ralph Brehm

PLoS One. 2018; 13(6): e0198100. Published online 2018 Jun 1. doi: 10.1371/journal.pone.0198100

PMCID:: PMC5983412

Article PDF–40M

Select item 565967615.

Sertoli Cell Number Defines and Predicts Germ and Leydig Cell Population Sizes in the Adult Mouse Testis

Diane Rebourcet, Annalucia Darbey, Ana Monteiro, Ugo Soffientini, Yi Ting Tsai, Ian Handel, Jean-Luc Pitetti, Serge Nef, Lee B. Smith, Peter J. O’Shaughnessy

Endocrinology. 2017 Sep 1; 158(9): 2955–2969. Published online 2017 Jul 5. doi: 10.1210/en.2017-00196

PMCID:: PMC5659676

Article

Select item 474191216.

Loss of Gata4 in Sertoli cells impairs the spermatogonial stem cell niche and causes germ cell exhaustion by attenuating chemokine signaling

Su-Ren Chen, Ji-Xin Tang, Jin-Mei Cheng, Jian Li, Cheng Jin, Xiao-Yu Li, Shou-Long Deng, Yan Zhang, Xiu-Xia Wang, Yi-Xun Liu

Oncotarget. 2015 Nov 10; 6(35): 37012–37027. Published online 2015 Oct 14. doi: 10.18632/oncotarget.6115

PMCID:: PMC4741912

Article PDF–13M

Select item 448893817.

Novel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli Cells

Julie Guillermet-Guibert, Lee B. Smith, Guillaume Halet, Maria A. Whitehead, Wayne Pearce, Diane Rebourcet, Kelly León, Pascale Crépieux, Gemma Nock, Maria Strömstedt, Malin Enerback, Claude Chelala, Mariona Graupera, John Carroll, Sabina Cosulich, Philippa T. K. Saunders, Ilpo Huhtaniemi, Bart Vanhaesebroeck

PLoS Genet. 2015 Jul; 11(7): e1005304. Published online 2015 Jul 1. doi: 10.1371/journal.pgen.1005304

PMCID:: PMC4488938

Article PDF–10M

Select item 414082318.

Sertoli Cells Maintain Leydig Cell Number and Peritubular Myoid Cell Activity in the Adult Mouse Testis

Diane Rebourcet, Peter J. O’Shaughnessy, Ana Monteiro, Laura Milne, Lyndsey Cruickshanks, Nathan Jeffrey, Florian Guillou, Tom C. Freeman, Rod T. Mitchell, Lee B. Smith

PLoS One. 2014; 9(8): e105687. Published online 2014 Aug 21. doi: 10.1371/journal.pone.0105687

PMCID:: PMC4140823

Article PDF–17M

Select item 401109019.

Sertoli cells control peritubular myoid cell fate and support adult Leydig cell development in the prepubertal testis

Diane Rebourcet, Peter J. O'Shaughnessy, Jean-Luc Pitetti, Ana Monteiro, Laura O'Hara, Laura Milne, Yi Ting Tsai, Lyndsey Cruickshanks, Dieter Riethmacher, Florian Guillou, Rod T. Mitchell, Rob van ’t Hof, Tom C. Freeman, Serge Nef, Lee B. Smith

Development. 2014 May; 141(10): 2139–2149. doi: 10.1242/dev.107029