PMC Links for Gene (Select 116477) - PMC

Links from Gene

Items: 1 to 20 of 25

<< First< Prev

Page of 2

Select item 86847251.

Radha Akella, John M. Humphreys, Kamil Sekulski, Haixia He, Mateusz Durbacz, Srinivas Chakravarthy, Joanna Liwocha, Zuhair J. Mohammed, Chad A. Brautigam, Elizabeth J. Goldsmith

Mol Biol Cell. 2021 Aug 19; 32(18): 1614–1623. doi: 10.1091/mbc.E20-01-0089

PMCID:: PMC8684725

Abstract Article PDF–3.5M

Select item 79140022.

A phosphorylated intermediate in the activation of WNK kinases

Radha Akella, Mateusz A. Drozdz, John M. Humphreys, Jenny Jiou, Mateusz Z. Durbacz, Zuhair J. Mohammed, Haixia He, Joanna Liwocha, Kamil Sekulski, Elizabeth J. Goldsmith

Biochemistry. Author manuscript; available in PMC 2021 Feb 27.

Published in final edited form as: Biochemistry. 2020 May 12; 59(18): 1747–1755. Published online 2020 Apr 24. doi: 10.1021/acs.biochem.0c00146

PMCID:: PMC7914002

Abstract Article PDF–1.4M

Select item 68896093.

Regulation of CFTR Bicarbonate Channel Activity by WNK1: Implications for Pancreatitis and CFTR-Related Disorders

Yonjung Kim, Ikhyun Jun, Dong Hoon Shin, Jihoon G. Yoon, He Piao, Jinsei Jung, Hyun Woo Park, Mary Hongying Cheng, Ivet Bahar, David C. Whitcomb, Min Goo Lee

Cell Mol Gastroenterol Hepatol. 2020; 9(1): 79–103. Published online 2019 Sep 24. doi: 10.1016/j.jcmgh.2019.09.003

PMCID:: PMC6889609

Abstract Article PDF–8.6M

Select item 41235274.

Chloride sensing by WNK1 kinase involves inhibition of autophosphorylation

Alexander T. Piala, Thomas M. Moon, Radha Akella, Haixia He, Melanie H. Cobb, Elizabeth J. Goldsmith

Sci Signal. Author manuscript; available in PMC 2014 Aug 6.

Published in final edited form as: Sci Signal. 2014 May 6; 7(324): ra41. Published online 2014 May 6. doi: 10.1126/scisignal.2005050

PMCID:: PMC4123527

Abstract Article PDF–1.0M

Select item 28203495.

WNK Kinases, Renal Ion Transport and Hypertension

Pedro San-Cristobal, Paola de los Heros, José Ponce-Coria, Erika Moreno, Gerardo Gamba

Am J Nephrol. 2008 Sep; 28(5): 860–870. Published online 2008 Jun 12. doi: 10.1159/000139639

PMCID:: PMC2820349

Abstract Article PDF–464K

Select item 5360446.

The kidney-specific WNK1 isoform is induced by aldosterone and stimulates epithelial sodium channel-mediated Na⁺ transport

Anikó Náray-Fejes-Tóth, Peter M. Snyder, Géza Fejes-Tóth

Proc Natl Acad Sci U S A. 2004 Dec 14; 101(50): 17434–17439. Published online 2004 Dec 6. doi: 10.1073/pnas.0408146101

PMCID:: PMC536044

Abstract Article PDF–396K

Select item 33755087.

Taurine Inhibits K⁺-Cl⁻ Cotransporter KCC2 to Regulate Embryonic Cl⁻ Homeostasis via With-no-lysine (WNK) Protein Kinase Signaling Pathway

Koichi Inoue, Tomonori Furukawa, Tatsuro Kumada, Junko Yamada, Tianying Wang, Rieko Inoue, Atsuo Fukuda

J Biol Chem. 2012 Jun 15; 287(25): 20839–20850. Published online 2012 Apr 27. doi: 10.1074/jbc.M111.319418

PMCID:: PMC3375508

Abstract Article PDF–1.6M

Select item 13605928.

Antagonistic regulation of ROMK by long and kidney-specific WNK1 isoforms

Ahmed Lazrak, Zhen Liu, Chou-Long Huang

Proc Natl Acad Sci U S A. 2006 Jan 31; 103(5): 1615–1620. Published online 2006 Jan 20. doi: 10.1073/pnas.0510609103

PMCID:: PMC1360592

Abstract Article PDF–408K

Select item 12371349.

The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases

Alberto C. Vitari, Maria Deak, Nick A. Morrice, Dario R. Alessi

Biochem J. 2005 Oct 1; 391(Pt 1): 17–24. Prepublished online 2005 Aug 5. Published online 2005 Sep 26. doi: 10.1042/BJ20051180

PMCID:: PMC1237134

Abstract Article PDF–742K

Select item 118197010.

Identification of a Novel Gene (HSN2) Causing Hereditary Sensory and Autonomic Neuropathy Type II through the Study of Canadian Genetic Isolates

Ronald G. Lafrenière, Marcia L. E. MacDonald, Marie-Pierre Dubé, Julie MacFarlane, Mary O’Driscoll, Bernard Brais, Sébastien Meilleur, Ryan R. Brinkman, Owen Dadivas, Terry Pape, Christèle Platon, Chris Radomski, Jenni Risler, Jay Thompson, Ana-Maria Guerra-Escobio, Gudarz Davar, Xandra O. Breakefield, Simon N. Pimstone, Roger Green, William Pryse-Phillips, Y. Paul Goldberg, H. Banfield Younghusband, Michael R. Hayden, Robin Sherrington, Guy A. Rouleau, Mark E. Samuels

Am J Hum Genet. 2004 May; 74(5): 1064–1073. Published online 2004 Apr 1. doi: 10.1086/420795

PMCID:: PMC1181970

Abstract Article PDF–674K

Select item 15259011.

WNK kinases regulate thiazide-sensitive Na-Cl cotransport

Chao-Ling Yang, Jordan Angell, Rose Mitchell, David H. Ellison

J Clin Invest. 2003 Apr 1; 111(7): 1039–1045. doi: 10.1172/JCI17443

PMCID:: PMC152590

Abstract Article PDF–546K

Select item 553678812.

WNK-Cab39-NKCC1 signaling increases the susceptibility to ischemic brain damage in hypertensive rats

Mohammad Iqbal H Bhuiyan, Shanshan Song, Hui Yuan, Gulnaz Begum, Julia Kofler, Kristopher T Kahle, Sung-Sen Yang, Shih-Hua Lin, Seth L Alper, Arohan R Subramanya, Dandan Sun

J Cereb Blood Flow Metab. 2017 Aug; 37(8): 2780–2794. Published online 2016 Jan 1. doi: 10.1177/0271678X16675368

PMCID:: PMC5536788

Abstract Article PDF–1.5M

Select item 969928313.

WNK kinases sense molecular crowding and rescue cell volume via phase separation

Cary R. Boyd-Shiwarski, Daniel J. Shiwarski, Shawn E. Griffiths, Rebecca T. Beacham, Logan Norrell, Daryl E. Morrison, Jun Wang, Jacob Mann, William Tennant, Eric N. Anderson, Jonathan Franks, Michael Calderon, Kelly A. Connolly, Muhammad Umar Cheema, Claire J. Weaver, Lubika J. Nkashama, Claire C. Weckerly, Katherine E. Querry, Udai Bhan Pandey, Christopher J. Donnelly, Dandan Sun, Aylin R. Rodan, Arohan R. Subramanya

Cell. Author manuscript; available in PMC 2023 Nov 23.

Published in final edited form as: Cell. 2022 Nov 23; 185(24): 4488–4506.e20. Published online 2022 Oct 31. doi: 10.1016/j.cell.2022.09.042

PMCID:: PMC9699283

Abstract Article PDF–3.7M

Select item 291907814.

Serum and Glucocorticoid-induced Kinase (SGK) 1 and the Epithelial Sodium Channel Are Regulated by Multiple with No Lysine (WNK) Family Members

Charles J. Heise, Bing-e Xu, Staci L. Deaton, Seung-Kuy Cha, Chih-Jen Cheng, Svetlana Earnest, Samarpita Sengupta, Yu-Chi Juang, Steve Stippec, Yingda Xu, Yingming Zhao, Chou-Long Huang, Melanie H. Cobb

J Biol Chem. 2010 Aug 13; 285(33): 25161–25167. Published online 2010 Jun 4. doi: 10.1074/jbc.M110.103432

PMCID:: PMC2919078

Abstract Article PDF–1.6M

Select item 239873515.

Mutations in the nervous system–specific HSN2 exon of WNK1 cause hereditary sensory neuropathy type II

Masoud Shekarabi, Nathalie Girard, Jean-Baptiste Rivière, Patrick Dion, Martin Houle, André Toulouse, Ronald G. Lafrenière, Freya Vercauteren, Pascale Hince, Janet Laganiere, Daniel Rochefort, Laurence Faivre, Mark Samuels, Guy A. Rouleau

J Clin Invest. 2008 Jul 1; 118(7): 2496–2505. Published online 2008 Jun 2. doi: 10.1172/JCI34088

PMCID:: PMC2398735

Abstract Article PDF–1.2M

Select item 227706916.

SLC26A9 is a Cl⁻ channel regulated by the WNK kinases

Michael R Dorwart, Nikolay Shcheynikov, Youxue Wang, Steve Stippec, Shmuel Muallem

J Physiol. 2007 Oct 1; 584(Pt 1): 333–345. Published online 2007 Aug 2. doi: 10.1113/jphysiol.2007.135855

PMCID:: PMC2277069

Abstract Article PDF–660K

Select item 147976017.

Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1

Alberto C. Vitari, Jacob Thastrup, Fatema H. Rafiqi, Maria Deak, Nick A. Morrice, Håkan K. R. Karlsson, Dario R. Alessi

Biochem J. 2006 Jul 1; 397(Pt 1): 223–231. Prepublished online 2006 May 2. Published online 2006 Jun 14. doi: 10.1042/BJ20060220

PMCID:: PMC1479760

Abstract Article PDF–776K

Select item 429428718.

Identification of the WNK-SPAK/OSR1 Signaling Pathway in Rodent and Human Lenses

Irene Vorontsova, Leo Lam, Eric Delpire, Julie Lim, Paul Donaldson

Invest Ophthalmol Vis Sci. 2015 Jan; 56(1): 310–321. Published online 2015 Jan 13. doi: 10.1167/iovs.14-15911

PMCID:: PMC4294287

Abstract Article PDF–2.0M

Select item 499487319.

WNK1 kinase balances T cell adhesion versus migration in vivo

Robert Köchl, Flavian Thelen, Lesley Vanes, Tiago F. Brazao, Kathryn Fountain, Jian Xie, Chou-Long Huang, Ruth Lyck, Jens V. Stein, Victor L. J. Tybulewicz

Nat Immunol. Author manuscript; available in PMC 2017 Mar 1.

Published in final edited form as: Nat Immunol. 2016 Sep; 17(9): 1075–1083. Published online 2016 Jul 11. doi: 10.1038/ni.3495

Correction in:: Nat Immunol. 2017 Jan 19; 18(2): 246.

PMCID:: PMC4994873

Abstract Article PDF–2.3M

Select item 304937320.

IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway

Dongki Yang, Qin Li, Insuk So, Chou-Long Huang, Hideaki Ando, Akihiro Mizutani, George Seki, Katsuhiko Mikoshiba, Philip J. Thomas, Shmuel Muallem

J Clin Invest. 2011 Mar 1; 121(3): 956–965. Published online 2011 Feb 7. doi: 10.1172/JCI43475

PMCID:: PMC3049373

Abstract Article PDF–1.3M

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from Gene

Items: 1 to 20 of 25

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity