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Select item 45312641.

An epigenomic role of Fe65 in the cellular response to DNA damage

Seungjin Ryu, Francesca Teles, Giuseppina Minopoli, Tommaso Russo, Michael G. Rosenfeld, Yousin Suh

Mutat Res. Author manuscript; available in PMC 2016 Jun 1.

Published in final edited form as: Mutat Res. 2015 Jun; 776: 40–47. Published online 2015 Jan 28. doi: 10.1016/j.mrfmmm.2015.01.006

PMCID:: PMC4531264

Abstract Article PDF–1.6M

Select item 44472272.

FE65 and FE65L1 amyloid precursor protein–binding protein compound null mice display adult-onset cataract and muscle weakness

Jaehong Suh, Juliet A. Moncaster, Lirong Wang, Imran Hafeez, Joachim Herz, Rudolph E. Tanzi, Lee E. Goldstein, Suzanne Y. Guénette

FASEB J. 2015 Jun; 29(6): 2628–2639. Published online 2015 Mar 10. doi: 10.1096/fj.14-261453

PMCID:: PMC4447227

Abstract Article

Select item 36222463.

A macromolecular complex involving the amyloid precursor protein (APP) and the cytosolic adapter FE65 is a negative regulator of axon branching

Annat F. Ikin, Shasta L. Sabo, Lorene M. Lanier, Joseph D. Buxbaum

Mol Cell Neurosci. Author manuscript; available in PMC 2013 Apr 10.

Published in final edited form as: Mol Cell Neurosci. 2007 May; 35(1): 57–63. Published online 2007 Feb 8. doi: 10.1016/j.mcn.2007.02.003

PMCID:: PMC3622246

Abstract Article PDF–1008K

Select item 29828464.

Tyr⁶⁸² in the Intracellular Domain of APP Regulates Amyloidogenic APP Processing In Vivo

Alessia P. M. Barbagallo, Richard Weldon, Robert Tamayev, Dawang Zhou, Luca Giliberto, Oded Foreman, Luciano D'Adamio

PLoS One. 2010; 5(11): e15503. Published online 2010 Nov 16. doi: 10.1371/journal.pone.0015503

PMCID:: PMC2982846

Abstract Article PDF–746K

Select item 48998805.

FE65 and FE65L1 share common synaptic functions and genetically interact with the APP family in neuromuscular junction formation

Paul Strecker, Susann Ludewig, Marco Rust, Tabea A. Mundinger, Andreas Görlich, Elisa G. Krächan, Christina Mehrfeld, Joachim Herz, Martin Korte, Suzanne Y. Guénette, Stefan Kins

Sci Rep. 2016; 6: 25652. Published online 2016 May 11. doi: 10.1038/srep25652

PMCID:: PMC4899880

Abstract Article PDF–2.1M

Select item 28599376.

A Flanking Gene Problem Leads to the Discovery of a Gprc5b Splice Variant Predominantly Expressed in C57Bl/6J Mouse Brain and in Maturing Neurons

Bethany H. Cool, Guy C-K. Chan, Lin Lee, Junko Oshima, George M. Martin, Qubai Hu

PLoS One. 2010; 5(4): e10351. Published online 2010 Apr 26. doi: 10.1371/journal.pone.0010351

PMCID:: PMC2859937

Abstract Article PDF–728K

Select item 18582567.

Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease: a chronic oxidative paradigm for testing antioxidant therapies in vivo.

M. A. Pappolla, Y. J. Chyan, R. A. Omar, K. Hsiao, G. Perry, M. A. Smith, P. Bozner

Am J Pathol. 1998 Apr; 152(4): 871–877.

PMCID:: PMC1858256

Summary Page Browse PDF–2.9M

Select item 32816498.

Dual Regulation of Notch1 Signaling Pathway by Adaptor Protein Fe65

Mi-Yeon Kim, Jung-Soon Mo, Eun-Jung Ann, Ji-Hye Yoon, Hee-Sae Park

J Biol Chem. 2012 Feb 10; 287(7): 4690–4701. Published online 2011 Dec 23. doi: 10.1074/jbc.M111.289637

PMCID:: PMC3281649

Abstract Article PDF–2.4M

Select item 18007219.

Suppression of β-Amyloid Precursor Protein Signaling into the Nucleus by Estrogens Mediated through Complex Formation between the Estrogen Receptor and Fe65

Junying Bao, Chuanhai Cao, Xiaohui Zhang, Feng Jiang, Santo V. Nicosia, Wenlong Bai

Mol Cell Biol. 2007 Feb; 27(4): 1321–1333. Published online 2006 Nov 27. doi: 10.1128/MCB.01280-06

PMCID:: PMC1800721

Abstract Article PDF–1.2M

Select item 337994310.

FE65 as a link between VLDLR and APP to regulate their trafficking and processing

Sonya B Dumanis, Kelly A Chamberlain, Yoo Jin Sohn, Young Jin Lee, Suzanne Y Guénette, Toshiharu Suzuki, Paul M Mathews, Daniel TS Pak, G William Rebeck, Yoo-hun Suh, Hee-Sae Park, Hyang-Sook Hoe

Mol Neurodegener. 2012; 7: 9. Published online 2012 Mar 19. doi: 10.1186/1750-1326-7-9

PMCID:: PMC3379943

Abstract Article PDF–5.1M

Select item 266405611.

Fe65 is required for Tip60-directed histone H4 acetylation at DNA strand breaks

Maria Stante, Giuseppina Minopoli, Fabiana Passaro, Maddalena Raia, Luigi Del Vecchio, Tommaso Russo

Proc Natl Acad Sci U S A. 2009 Mar 31; 106(13): 5093–5098. Published online 2009 Mar 12. doi: 10.1073/pnas.0810869106

PMCID:: PMC2664056

Abstract Article PDF–870K

Select item 435634012.

Regulation of neuronal survival and morphology by the E3 ubiquitin ligase RNF157

A Matz, S-J Lee, N Schwedhelm-Domeyer, D Zanini, A Holubowska, M Kannan, M Farnworth, O Jahn, M C Göpfert, J Stegmüller

Cell Death Differ. 2015 Apr; 22(4): 626–642. Published online 2014 Oct 24. doi: 10.1038/cdd.2014.163

PMCID:: PMC4356340

Abstract Article PDF–6.3M

Select item 676306813.

c-Jun N-Terminal Kinase (JNK)-Interacting Protein-1b/Islet-Brain-1 Scaffolds Alzheimer's Amyloid Precursor Protein with JNK

Shuji Matsuda, Takashi Yasukawa, Yasuko Homma, Yuko Ito, Takako Niikura, Takako Hiraki, Shuichi Hirai, Shigeo Ohno, Yoshiko Kita, Masaoki Kawasumi, Keisuke Kouyama, Tokuo Yamamoto, John M. Kyriakis, Ikuo Nishimoto

J Neurosci. 2001 Sep 1; 21(17): 6597–6607. doi: 10.1523/JNEUROSCI.21-17-06597.2001

PMCID:: PMC6763068

Abstract Article PDF–555K

Select item 358653114.

A Role for FE65 in Controlling GnRH-1 Neurogenesis

Paolo E. Forni, Michele Fornaro, Suzanne Guénette, Susan Wray

J Neurosci. 2011 Jan 12; 31(2): 480–491. doi: 10.1523/JNEUROSCI.4698-10.2011

PMCID:: PMC3586531

Abstract Article PDF–5.5M

Select item 138351015.

Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development

Suzanne Guénette, Yang Chang, Thomas Hiesberger, James A Richardson, Christopher B Eckman, Elizabeth A Eckman, Robert E Hammer, Joachim Herz

EMBO J. 2006 Jan 25; 25(2): 420–431. Published online 2006 Jan 12. doi: 10.1038/sj.emboj.7600926

PMCID:: PMC1383510

Abstract Article PDF–707K

Select item 260527216.

Iron Deficiency Alters Expression of Genes Implicated in Alzheimer Disease Pathogenesis

Erik S. Carlson, Rhamy Magid, Anna Petryk, Michael K. Georgieff

Brain Res. Author manuscript; available in PMC 2009 Oct 27.

Published in final edited form as: Brain Res. 2008 Oct 27; 1237: 75–83. Published online 2008 Aug 7. doi: 10.1016/j.brainres.2008.07.109

PMCID:: PMC2605272

Abstract Article PDF–616K

Select item 472038917.

Mutations in DCHS1 Cause Mitral Valve Prolapse

Ronen Durst, Kimberly Sauls, David S Peal, Annemarieke deVlaming, Katelynn Toomer, Maire Leyne, Monica Salani, Michael E. Talkowski, Harrison Brand, Maëlle Perrocheau, Charles Simpson, Christopher Jett, Matthew R. Stone, Florie Charles, Colby Chiang, Stacey N. Lynch, Nabila Bouatia-Naji, Francesca N. Delling, Lisa A. Freed, Christophe Tribouilloy, Thierry Le Tourneau, Hervé LeMarec, Leticia Fernandez-Friera, Jorge Solis, Daniel Trujillano, Stephan Ossowski, Xavier Estivill, Christian Dina, Patrick Bruneval, Adrian Chester, Jean-Jacques Schott, Kenneth D. Irvine, Yaopan Mao, Andy Wessels, Tahirali Motiwala, Michel Puceat, Yoshikazu Tsukasaki, Donald R. Menick, Harinath Kasiganesan, Xingju Nie, Ann-Marie Broome, Katherine Williams, Amanda Johnson, Roger R. Markwald, Xavier Jeunemaitre, Albert Hagege, Robert A. Levine, David J. Milan, Russell A. Norris, Susan A. Slaugenhaupt

Nature. Author manuscript; available in PMC 2016 Mar 3.

Published in final edited form as: Nature. 2015 Sep 3; 525(7567): 109–113. Published online 2015 Aug 10. doi: 10.1038/nature14670

PMCID:: PMC4720389

Abstract Article PDF–3.6M

Select item 266041918.

FE65 Binds Teashirt, Inhibiting Expression of the Primate-Specific Caspase-4

Yuji Kajiwara, Afia Akram, Pavel Katsel, Vahram Haroutunian, James Schmeidler, Gary Beecham, Jonathan L. Haines, Margaret A. Pericak-Vance, Joseph D. Buxbaum

PLoS One. 2009; 4(4): e5071. Published online 2009 Apr 3. doi: 10.1371/journal.pone.0005071

PMCID:: PMC2660419

Abstract Article PDF–606K

Select item 217156619.

Coordinated transport of phosphorylated amyloid-β precursor protein and c-Jun NH₂-terminal kinase–interacting protein-1

Zoia Muresan, Virgil Muresan

J Cell Biol. 2005 Nov 21; 171(4): 615–625. doi: 10.1083/jcb.200502043

PMCID:: PMC2171566

Abstract Article PDF–2.6M

Select item 335650520.

Congenital Asplenia in Mice and Humans with Mutations in a Pbx/Nkx2-5/p15 Module

Matthew Koss, Alexandre Bolze, Andrea Brendolan, Matilde Saggese, Terence D. Capellini, Ekaterina Bojilova, Bertrand Boisson, Owen W.J. Prall, David Elliott, Mark Solloway, Elisa Lenti, Chisa Hidaka, Ching-Pin Chang, Nizar Mahlaoui, Richard P. Harvey, Jean-Laurent Casanova, Licia Selleri

Dev Cell. Author manuscript; available in PMC 2013 May 15.

Published in final edited form as: Dev Cell. 2012 May 15; 22(5): 913–926. Published online 2012 May 3. doi: 10.1016/j.devcel.2012.02.009

PMCID:: PMC3356505

Abstract Article PDF–6.8M

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