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Select item 103778871.

Individual Contributions of Amido Acid Residues Tyr122, Ile168, and Asp173 to the Activity and Substrate Specificity of Human DNA Dioxygenase ABH2

Anastasiia T. Davletgildeeva, Timofey E. Tyugashev, Mingxing Zhao, Nikita A. Kuznetsov, Alexander A. Ishchenko, Murat Saparbaev, Aleksandra A. Kuznetsova

Cells. 2023 Jul; 12(14): 1839. Published online 2023 Jul 13. doi: 10.3390/cells12141839

PMCID:: PMC10377887

Abstract Article PDF–5.6M

Select item 93707052.

Conformational Dynamics of Human ALKBH2 Dioxygenase in the Course of DNA Repair as Revealed by Stopped-Flow Fluorescence Spectroscopy

Lyubov Yu. Kanazhevskaya, Denis A. Smyshliaev, Nadezhda A. Timofeyeva, Alexander A. Ishchenko, Murat Saparbaev, Nikita A. Kuznetsov, Olga S. Fedorova

Molecules. 2022 Aug; 27(15): 4960. Published online 2022 Aug 4. doi: 10.3390/molecules27154960

PMCID:: PMC9370705

Abstract Article PDF–3.9M

Select item 77315533.

ALKBH2 inhibition alleviates malignancy in colorectal cancer by regulating BMI1-mediated activation of NF-κB pathway

Bingxin Ke, Kejun Ye, Shaobing Cheng

World J Surg Oncol. 2020; 18: 328. Published online 2020 Dec 10. doi: 10.1186/s12957-020-02106-0

PMCID:: PMC7731553

Abstract Article PDF–4.8M

Select item 35784824.

The DNA repair protein ALKBH2 mediates temozolomide resistance in human glioblastoma cells

Tor-Christian Aase Johannessen, Lars Prestegarden, Amra Grudic, Monika E. Hegi, Berit Bølge Tysnes, Rolf Bjerkvig

Neuro Oncol. 2013 Mar; 15(3): 269–278. Published online 2012 Dec 20. doi: 10.1093/neuonc/nos301

PMCID:: PMC3578482

Abstract Article PDF–303K

Select item 33925265.

Duplex Interrogation by a Direct DNA Repair Protein in Search of Base Damage

Chengqi Yi, Baoen Chen, Bo Qi, Wen Zhang, Guifang Jia, Liang Zhang, Charles J. Li, Aaron R. Dinner, Cai-Guang Yang, Chuan He

Nat Struct Mol Biol. Author manuscript; available in PMC 2013 Jan 1.

Published in final edited form as: Nat Struct Mol Biol. 2012 Jul; 19(7): 671–676. Published online 2012 Jun 3. doi: 10.1038/nsmb.2320

PMCID:: PMC3392526

Abstract Article PDF–1.2M

Select item 31240146.

XAS Structural Investigation of Early Intermediates in the Mechanism of DNA Repair by Human ABH2

Nitai Charan Giri, Hong Sun, Haobin Chen, Max Costa, Michael J. Maroney

Biochemistry. Author manuscript; available in PMC 2012 Jun 7.

Published in final edited form as: Biochemistry. 2011 Jun 7; 50(22): 5067–5076. Published online 2011 May 11. doi: 10.1021/bi101668x

PMCID:: PMC3124014

Abstract Article PDF–2.0M

Select item 29200317.

TP53 regulates human AlkB homologue 2 expression in glioma resistance to Photofrin-mediated photodynamic therapy

S Y Lee, S K Luk, C P Chuang, S P Yip, S S T To, Y M B Yung

Br J Cancer. 2010 Jul 27; 103(3): 362–369. Published online 2010 Jul 27. doi: 10.1038/sj.bjc.6605797

PMCID:: PMC2920031

Abstract Article PDF–482K

Select item 76697308.

Insights into the Direct Oxidative Repair of Etheno Lesions: MD and QM/MM Study on the Substrate Scope of ALKBH2 and AlkB

Stefan A. P. Lenz, Deyu Li, Stacey D. Wetmore

DNA Repair (Amst) Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: DNA Repair (Amst). 2020 Dec; 96: 102944. Published online 2020 Sep 9. doi: 10.1016/j.dnarep.2020.102944

PMCID:: PMC7669730

Abstract Article PDF–1.9M

Select item 76571769.

ALKBH2, a novel AlkB homologue, contributes to human bladder cancer progression by regulating MUC1 expression

Tomomi Fujii, Keiji Shimada, Satoshi Anai, Kiyohide Fujimoto, Noboru Konishi

Cancer Sci. 2013 Mar; 104(3): 321–327. Published online 2013 Feb 14. doi: 10.1111/cas.12089

PMCID:: PMC7657176

Abstract Article PDF–1.1M

Select item 520690410.

The interaction between ALKBH2 DNA repair enzyme and PCNA is direct, mediated by the hydrophobic pocket of PCNA and perturbed in naturally-occurring ALKBH2 variants

Dragony Fu, Leona D. Samson, Ullrich Hübscher, Barbara van Loon

DNA Repair (Amst) Author manuscript; available in PMC 2017 Jan 3.

Published in final edited form as: DNA Repair (Amst). 2015 Nov; 35: 13–18. Published online 2015 Sep 14. doi: 10.1016/j.dnarep.2015.09.008

PMCID:: PMC5206904

Abstract Article PDF–227K

Select item 445193911.

Differential repair of etheno-DNA adducts by bacterial and human AlkB proteins

Daria Zdżalik, Anna Domańska, Paulina Prorok, Konrad Kosicki, Erwin van den Born, Pål Ø. Falnes, Carmelo J. Rizzo, F. Peter Guengerich, Barbara Tudek

DNA Repair (Amst) Author manuscript; available in PMC 2016 Jun 1.

Published in final edited form as: DNA Repair (Amst). 2015 Jun; 30: 1–10. Published online 2015 Mar 5. doi: 10.1016/j.dnarep.2015.02.021

PMCID:: PMC4451939

Abstract Article PDF–833K

Select item 325395912.

Direct Repair of 3,N⁴-Ethenocytosine by the Human ALKBH2 Dioxygenase is blocked by the AAG/MPG Glycosylase

Dragony Fu, Leona D. Samson

DNA Repair (Amst) Author manuscript; available in PMC 2013 Jan 2.

Published in final edited form as: DNA Repair (Amst). 2012 Jan 2; 11(1): 46–52. Published online 2011 Nov 11. doi: 10.1016/j.dnarep.2011.10.004

PMCID:: PMC3253959

Abstract Article PDF–821K

Select item 296523813.

Divergent β-hairpins determine double-strand versus single-strand substrate recognition of human AlkB-homologues 2 and 3

Vivi Talstad Monsen, Ottar Sundheim, Per Arne Aas, Marianne P. Westbye, Mirta M. L. Sousa, Geir Slupphaug, Hans E. Krokan

Nucleic Acids Res. 2010 Oct; 38(19): 6447–6455. Published online 2010 Jun 4. doi: 10.1093/nar/gkq518

PMCID:: PMC2965238

Abstract Article PDF–3.6M

Select item 284418614.

Nickel Ions Inhibit Histone Demethylase JMJD1A and DNA Repair Enzyme ABH2 by Replacing the Ferrous Iron in the Catalytic Centers

Haobin Chen, Nitai Charan Giri, Ronghe Zhang, Kenichi Yamane, Yi Zhang, Michael Maroney, Max Costa

J Biol Chem. 2010 Mar 5; 285(10): 7374–7383. Published online 2009 Dec 30. doi: 10.1074/jbc.M109.058503

Correction in:: J Biol Chem. 2017 Jun 23; 292(25): 10743.

PMCID:: PMC2844186

Abstract Article PDF–1.4M

Select item 274218215.

Identification of a novel, widespread, and functionally important PCNA-binding motif

Karin M. Gilljam, Emadoldin Feyzi, Per A. Aas, Mirta M.L. Sousa, Rebekka Müller, Cathrine B. Vågbø, Tara C. Catterall, Nina B. Liabakk, Geir Slupphaug, Finn Drabløs, Hans E. Krokan, Marit Otterlei

J Cell Biol. 2009 Sep 7; 186(5): 645–654. doi: 10.1083/jcb.200903138