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Items: 1 to 20 of 109

1.
Increased calpain-1 in mitochondria induces dilated heart failure in mice: role of mitochondrial superoxide anion
Ting Cao, Shuai Fan, Dong Zheng, Grace Wang, Yong Yu, Ruizhen Chen, Long-Sheng Song, Guo-Chang Fan, Zhuxu Zhang, Tianqing Peng
Basic Res Cardiol. Author manuscript; available in PMC 2022 Sep 6.
Published in final edited form as: Basic Res Cardiol. 2019 Mar 15; 114(3): 17. Published online 2019 Mar 15. doi: 10.1007/s00395-019-0726-1
PMCID:
PMC9444798
AbstractArticlePDF–1.8M
2.
Calpain‐1 mediates vascular remodelling and fibrosis via HIF‐1α in hypoxia‐induced pulmonary hypertension
Haiyan Deng, Xiaoxue Tian, Hening Sun, Huan Liu, Meili Lu, Hongxin Wang
J Cell Mol Med. 2022 May; 26(10): 2819–2830. Published online 2022 Apr 1. doi: 10.1111/jcmm.17295
PMCID:
PMC9097838
AbstractArticlePDF–12M
3.
Photoreceptor Cell Calcium Dysregulation and Calpain Activation Promote Pathogenic Photoreceptor Oxidative Stress and Inflammation in Prodromal Diabetic Retinopathy
Aicha Saadane, Yunpeng Du, Wallace B. Thoreson, Masaru Miyagi, Emma M. Lessieur, Jianying Kiser, Xiangyi Wen, Bruce A. Berkowitz, Timothy S. Kern
Am J Pathol. 2021 Oct; 191(10): 1805–1821. doi: 10.1016/j.ajpath.2021.06.006
PMCID:
PMC8579242
AbstractArticlePDF–2.9M
4.
Calpain-1 ablation partially rescues disease-associated hallmarks in models of Machado-Joseph disease
Jonasz J Weber, Eva Haas, Yacine Maringer, Stefan Hauser, Nicolas L P Casadei, Athar H Chishti, Olaf Riess, Jeannette Hübener-Schmid
Hum Mol Genet. 2020 Apr 15; 29(6): 892–906. Published online 2020 Jan 21. doi: 10.1093/hmg/ddaa010
PMCID:
PMC7158375
AbstractArticlePDF–1.5M
5.
In vivo calpain knockdown using delivery of siRNA
Xiaoqian Liu, Guochang Hu
Methods Mol Biol. Author manuscript; available in PMC 2020 Jan 1.
Published in final edited form as: Methods Mol Biol. 2019; 1915: 219–232. doi: 10.1007/978-1-4939-8988-1_17
PMCID:
PMC6548319
AbstractArticlePDF–420K
6.
MECHANISTIC ROLE OF THE CALCIUM-DEPENDENT PROTEASE CALPAIN IN THE ENDOTHELIAL DYSFUNCTION INDUCED BY MYELOPEROXIDASE
Zienab Etwebi, Gavin Landesberg, Kyle Preston, Satoru Eguchi, Rosario Scalia
Hypertension. Author manuscript; available in PMC 2019 Apr 16.
Published in final edited form as: Hypertension. 2018 Apr; 71(4): 761–770. doi: 10.1161/HYPERTENSIONAHA.117.10305
PMCID:
PMC6467284
AbstractArticlePDF–1.5M
7.
Calpain-1 deletion impairs mGluR-dependent LTD and fear memory extinction
Guoqi Zhu, Victor Briz, Jeff Seinfeld, Yan Liu, Xiaoning Bi, Michel Baudry
Sci Rep. 2017; 7: 42788. Published online 2017 Feb 16. doi: 10.1038/srep42788
PMCID:
PMC5311935
AbstractArticlePDF–1.9M
8.
Attenuation of Blood-Brain Barrier Breakdown and Hyperpermeability by Calpain Inhibition
Himakarnika Alluri, Marcene Grimsley, Chinchusha Anasooya Shaji, Kevin Paul Varghese, Shenyuan L. Zhang, Chander Peddaboina, Bobby Robinson, Madhava R. Beeram, Jason H. Huang, Binu Tharakan
J Biol Chem. 2016 Dec 30; 291(53): 26958–26969. Published online 2016 Nov 8. doi: 10.1074/jbc.M116.735365
PMCID:
PMC5207131
AbstractArticlePDF–1.4M
9.
Genetic inactivation of calpain-1 attenuates pain sensitivity in a humanized mouse model of sickle cell disease
Jennifer O. Nwankwo, Jianxun Lei, Jian Xu, Alicia Rivera, Kalpna Gupta, Athar H. Chishti
Haematologica. 2016 Oct; 101(10): e397–e400. doi: 10.3324/haematol.2016.148106
PMCID:
PMC5046659
ArticlePDF–773K
10.
Different Patterns of Electrical Activity Lead to Long-term Potentiation by Activating Different Intracellular Pathways
Guoqi Zhu, Yan Liu, Yubin Wang, Xiaoning Bi, Michel Baudry
J Neurosci. 2015 Jan 14; 35(2): 621–633. doi: 10.1523/JNEUROSCI.2193-14.2015
PMCID:
PMC4293414
AbstractArticlePDF–2.6M
11.
Specific Calpain Inhibition by Calpastatin Prevents Tauopathy and Neurodegeneration and Restores Normal Lifespan in Tau P301L Mice
Mala V. Rao, Mary Kate McBrayer, Jabbar Campbell, Asok Kumar, Audrey Hashim, Henry Sershen, Philip H. Stavrides, Masuo Ohno, Michael Hutton, Ralph A. Nixon
J Neurosci. 2014 Jul 9; 34(28): 9222–9234. doi: 10.1523/JNEUROSCI.1132-14.2014
PMCID:
PMC4087203
AbstractArticlePDF–2.8M
12.
Calpain-1 contributes to IgE-mediated mast cell activation
Zhengli Wu, Xiaochun Chen, Fang Liu, Wei Chen, Ping Wu, Adam J. Wieschhaus, Athar H. Chishti, Paul A. Roche, Wei-Min Chen, Tong-Jun Lin
J Immunol. Author manuscript; available in PMC 2015 Jun 1.
Published in final edited form as: J Immunol. 2014 Jun 1; 192(11): 5130–5139. Published online 2014 Apr 23. doi: 10.4049/jimmunol.1301677
PMCID:
PMC4038093
AbstractArticlePDF–1.6M
13.
The effects of Capn1 gene inactivation on skeletal muscle growth, development, and atrophy, and the compensatory role of other proteolytic systems
C. M. Kemp, W. T. Oliver, T. L. Wheeler, A. H. Chishti, M. Koohmaraie
J Anim Sci. Author manuscript; available in PMC 2014 Mar 23.
Published in final edited form as: J Anim Sci. 2013 Jul; 91(7): 3155–3167. doi: 10.2527/jas.2012-5737
PMCID:
PMC3962768
AbstractArticlePDF–2.2M
14.
Calpain-mediated regulation of platelet signaling pathways
Shafi M. Kuchay, Athar H. Chishti
Curr Opin Hematol. Author manuscript; available in PMC 2014 Mar 19.
Published in final edited form as: Curr Opin Hematol. 2007 May; 14(3): 249–254. doi: 10.1097/MOH.0b013e3280ef68f8
PMCID:
PMC3959858
AbstractArticlePDF–84K
15.
Targeted gene inactivation reveals a functional role of calpain-1 in platelet spreading
S. M. KUCHAY, A. J. WIESCHHAUS, M. MARINKOVIC, I. M. HERMAN, A. H. CHISHTI
J Thromb Haemost. Author manuscript; available in PMC 2014 Mar 18.
Published in final edited form as: J Thromb Haemost. 2012 Jun; 10(6): 1120–1132. doi: 10.1111/j.1538-7836.2012.04715.x
PMCID:
PMC3956748
AbstractArticlePDF–3.0M
16.
Calpain-1 knockout reveals broad effects on erythrocyte deformability and physiology
Adam Wieschhaus, Anwar Khan, Asma Zaidi, Henry Rogalin, Toshihiko Hanada, Fei Liu, Lucia De Franceschi, Carlo Brugnara, Alicia Rivera, Athar H. Chishti
Biochem J. Author manuscript; available in PMC 2014 Mar 15.
Published in final edited form as: Biochem J. 2012 Nov 15; 448(1): 141–152. doi: 10.1042/BJ20121008
PMCID:
PMC3955119
AbstractArticlePDF–2.3M
17.
Targeted Gene Inactivation of Calpain-1 Suppresses Cortical Degeneration Due to Traumatic Brain Injury and Neuronal Apoptosis Induced by Oxidative Stress
Kaori H. Yamada, Dorothy A. Kozlowski, Stacey E. Seidl, Steven Lance, Adam J. Wieschhaus, Premanand Sundivakkam, Chinnaswamy Tiruppathi, Imran Chishti, Ira M. Herman, Shafi M. Kuchay, Athar H. Chishti
J Biol Chem. 2012 Apr 13; 287(16): 13182–13193. Published online 2012 Feb 24. doi: 10.1074/jbc.M111.302612
PMCID:
PMC3339949
AbstractArticlePDF–2.1M
18.
Inhibition of calpain prevents muscle weakness and disruption of sarcomere structure during hindlimb suspension
Jay J. Salazar, Daniel E. Michele, Susan V. Brooks
J Appl Physiol (1985) 2010 Jan; 108(1): 120–127. Published online 2009 Nov 5. doi: 10.1152/japplphysiol.01080.2009
PMCID:
PMC2964277
AbstractArticle
19.
Calpain-1 is required for hydrogen peroxide-induced myotube atrophy
J. M. McClung, A. R. Judge, E. E. Talbert, S. K. Powers
Am J Physiol Cell Physiol. 2009 Feb; 296(2): C363–C371. Published online 2008 Dec 24. doi: 10.1152/ajpcell.00497.2008
PMCID:
PMC2643855
AbstractArticle
20.
Calpain Is Required for Normal Osteoclast Function and Is Down-regulated by Calcitonin
Marilena Marzia, Riccardo Chiusaroli, Lynn Neff, Na-Young Kim, Athar H. Chishti, Roland Baron, William C. Horne
J Biol Chem. Author manuscript; available in PMC 2006 Sep 21.
Published in final edited form as: J Biol Chem. 2006 Apr 7; 281(14): 9745–9754. Published online 2006 Feb 3. doi: 10.1074/jbc.M513516200
PMCID:
PMC1570620
AbstractArticlePDF–1002K

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