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Select item 67628251.

Death in the Balance: Alternative Participation of the Caspase-2 and -9 Pathways in Neuronal Death Induced by Nerve Growth Factor Deprivation

Carol M. Troy, Sylvia A. Rabacchi, Justin B. Hohl, James M. Angelastro, Lloyd A. Greene, Michael L. Shelanski

J Neurosci. 2001 Jul 15; 21(14): 5007–5016. doi: 10.1523/JNEUROSCI.21-14-05007.2001

Correction in:: J Neurosci. 2001 Aug 15; 21(16): np.

PMCID:: PMC6762825

Article PDF–1.5M

Select item 66890332.

Caspase-2 promotes AMPA receptor internalization and cognitive flexibility via mTORC2-AKT-GSK3β signaling

Zhi-Xiang Xu, Ji-Wei Tan, Haifei Xu, Cassandra J. Hill, Olga Ostrovskaya, Kirill A. Martemyanov, Baoji Xu

Nat Commun. 2019; 10: 3622. Published online 2019 Aug 9. doi: 10.1038/s41467-019-11575-1

PMCID:: PMC6689033

Article PDF–2.5M

Select item 61599283.

ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P

Ju Youn Kim, Ricard Garcia-Carbonell, Shinichiro Yamachika, Peng Zhao, Debanjan Dhar, Rohit Loomba, Randal J Kaufman, Alan R Saltiel, Michael Karin

Cell. Author manuscript; available in PMC 2019 Sep 20.

Published in final edited form as: Cell. 2018 Sep 20; 175(1): 133–145.e15. Published online 2018 Sep 13. doi: 10.1016/j.cell.2018.08.020

PMCID:: PMC6159928

Article PDF–1.5M

Select item 54424224.

Caspase-2-mediated cell death is required for deleting aneuploid cells

S Dawar, Y Lim, J Puccini, M White, P Thomas, L Bouchier-Hayes, D R Green, L Dorstyn, S Kumar

Oncogene. 2017 May 11; 36(19): 2704–2714. Published online 2016 Dec 19. doi: 10.1038/onc.2016.423

PMCID:: PMC5442422

Article PDF–1.4M

Select item 53991905.

Caspase-2 promotes obesity, the metabolic syndrome and nonalcoholic fatty liver disease

M V Machado, G A Michelotti, M L Jewell, T A Pereira, G Xie, R T Premont, A M Diehl

Cell Death Dis. 2016 Feb; 7(2): e2096. Published online 2016 Feb 18. doi: 10.1038/cddis.2016.19

PMCID:: PMC5399190

Article PDF–5.2M

Select item 52609896.

Impaired haematopoietic stem cell differentiation and enhanced skewing towards myeloid progenitors in aged caspase-2-deficient mice

Swati Dawar, Nur Hezrin Shahrin, Nikolina Sladojevic, Richard J D'Andrea, Loretta Dorstyn, Devendra K Hiwase, Sharad Kumar

Cell Death Dis. 2016 Dec; 7(12): e2509. Published online 2016 Dec 1. doi: 10.1038/cddis.2016.406

PMCID:: PMC5260989

Article PDF–1.3M

Select item 50412007.

Caspase-2 deficiency accelerates chemically induced liver cancer in mice

S Shalini, A Nikolic, C H Wilson, J Puccini, N Sladojevic, J Finnie, L Dorstyn, S Kumar

Cell Death Differ. 2016 Oct; 23(10): 1727–1736. Published online 2016 Aug 12. doi: 10.1038/cdd.2016.81

PMCID:: PMC5041200

Article PDF–2.3M

Select item 46697658.

C H Wilson, S Shalini, A Filipovska, T R Richman, S Davies, S D Martin, S L McGee, J Puccini, A Nikolic, L Dorstyn, S Kumar

Cell Death Dis. 2015 Jan; 6(1): e1597. Published online 2015 Jan 22. doi: 10.1038/cddis.2014.567

PMCID:: PMC4669765

Article PDF–1.7M

Select item 44543179.

An unexpected role for caspase-2 in neuroblastoma

L Dorstyn, J Puccini, A Nikolic, S Shalini, C H Wilson, M D Norris, M Haber, S Kumar

Cell Death Dis. 2014 Aug; 5(8): e1383. Published online 2014 Aug 21. doi: 10.1038/cddis.2014.342

PMCID:: PMC4454317

Article PDF–3.4M

Select item 409116810.

A nonapoptotic role for CASP2/caspase 2: Modulation of autophagy

Meenakshi Tiwari, Lokendra K Sharma, Difernando Vanegas, Danielle A Callaway, Yidong Bai, James D Lechleiter, Brian Herman

Autophagy. 2014 Jun 1; 10(6): 1054–1070. Published online 2014 Apr 4. doi: 10.4161/auto.28528

Correction in:: Autophagy. 2017; 13(3): 637.

PMCID:: PMC4091168

Article PDF–3.5M

Select item 397223611.

Caspase-2 Maintains Bone Homeostasis by Inducing Apoptosis of Oxidatively-Damaged Osteoclasts

Ramaswamy Sharma, Danielle Callaway, Difernando Vanegas, Michelle Bendele, Marisa Lopez-Cruzan, Diane Horn, Teja Guda, Roberto Fajardo, Sherry Abboud-Werner, Brian Herman

PLoS One. 2014; 9(4): e93696. Published online 2014 Apr 1. doi: 10.1371/journal.pone.0093696

PMCID:: PMC3972236

Article PDF–8.9M

Select item 374151112.

Caspase-2 as a tumour suppressor

J Puccini, L Dorstyn, S Kumar

Cell Death Differ. 2013 Sep; 20(9): 1133–1139. Published online 2013 Jun 28. doi: 10.1038/cdd.2013.87

PMCID:: PMC3741511

Article PDF–709K

Select item 374149713.

Genetic deletion of caspase-2 accelerates MMTV/c-neu-driven mammary carcinogenesis in mice

M J Parsons, L McCormick, L Janke, A Howard, L Bouchier-Hayes, D R Green

Cell Death Differ. 2013 Sep; 20(9): 1174–1182. Published online 2013 May 3. doi: 10.1038/cdd.2013.38

PMCID:: PMC3741497

Article PDF–1.3M

Select item 365734514.

Loss of caspase-2 accelerates age-dependent alterations in mitochondrial production of reactive oxygen species

Marisa Lopez-Cruzan, Brian Herman

Biogerontology. 2013; 14(2): 121–130. Published online 2013 Mar 16. doi: 10.1007/s10522-013-9415-x

PMCID:: PMC3657345

Article PDF–1.2M

Select item 342554215.

Caspase-2-Dependent Dendritic Cell Death, Maturation, and Priming of T Cells in Response to Brucella abortus Infection

Xinna Li, Yongqun He

PLoS One. 2012; 7(8): e43512. Published online 2012 Aug 22. doi: 10.1371/journal.pone.0043512

PMCID:: PMC3425542

Article PDF–711K

Select item 339263016.

Caspase-2 deficiency promotes aberrant DNA-damage response and genetic instability

L Dorstyn, J Puccini, C H Wilson, S Shalini, M Nicola, S Moore, S Kumar

Cell Death Differ. 2012 Aug; 19(8): 1288–1298. Published online 2012 Apr 13. doi: 10.1038/cdd.2012.36

Correction in:: Cell Death Differ. 2012 Aug; 19(8): 1411.

PMCID:: PMC3392630

Article PDF–8.2M

Select item 339262617.

Impaired antioxidant defence and accumulation of oxidative stress in caspase-2-deficient mice

S Shalini, L Dorstyn, C Wilson, J Puccini, L Ho, S Kumar

Cell Death Differ. 2012 Aug; 19(8): 1370–1380. Published online 2012 Feb 17. doi: 10.1038/cdd.2012.13

PMCID:: PMC3392626

Article PDF–997K

Select item 312581918.

Proinflammatory Caspase-2-Mediated Macrophage Cell Death Induced by a Rough Attenuated Brucella suis Strain

Fang Chen, Xicheng Ding, Ying Ding, Zuoshuang Xiang, Xinna Li, Debashis Ghosh, Gerhardt G. Schurig, Nammalwar Sriranganathan, Stephen M. Boyle, Yongqun He

Infect Immun. 2011 Jun; 79(6): 2460–2469. doi: 10.1128/IAI.00050-11