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Select item 101157371.

IKK1 aggravates ischemia–reperfusion kidney injury by promoting the differentiation of effector T cells

Ning Song, Yang Xu, Hans-Joachim Paust, Ulf Panzer, Maria Mercedes de las Noriega, Linlin Guo, Thomas Renné, Jiabin Huang, Xianglin Meng, Mingyan Zhao, Friedrich Thaiss

Cell Mol Life Sci. 2023; 80(5): 125. Published online 2023 Apr 19. doi: 10.1007/s00018-023-04763-2

PMCID:: PMC10115737

Article PDF–5.3M

Select item 89409892.

Conditional loss of IKKα in Osterix + cells has no effect on bone but leads to age-related loss of peripheral fat

Jennifer L. Davis, Nitin Kumar Pokhrel, Linda Cox, Nidhi Rohatgi, Roberta Faccio, Deborah J. Veis

Sci Rep. 2022; 12: 4915. Published online 2022 Mar 22. doi: 10.1038/s41598-022-08914-6

PMCID:: PMC8940989

Article PDF–5.0M

Select item 86709703.

Deficiency of IKKα in Macrophages Mitigates Fibrosis Progression in the Kidney after Renal Ischemia-Reperfusion Injury

Feng Zhang, Li Fan, Hao Zhang, Wen-juan Huang, Dong Sun, Bin-bin Pan, Xin Wan, Chang-Chun Cao

J Immunol Res. 2021; 2021: 5521051. Published online 2021 Dec 7. doi: 10.1155/2021/5521051

PMCID:: PMC8670970

Article PDF–2.6M

Select item 81913884.

IKKα deficiency disrupts the development of marginal zone and follicular B cells

Mumtaz Y. Balkhi, Jami Willette-Brown, Gabor Wittmann, Yinling Hu

Genes Immun. Author manuscript; available in PMC 2021 Jun 10.

Published in final edited form as: Genes Immun. 2019 Mar; 20(3): 224–233. Published online 2018 May 8. doi: 10.1038/s41435-018-0025-0

PMCID:: PMC8191388

Article PDF–1.0M

Select item 46881895.

A quinoxaline urea analog uncouples inflammatory and pro-survival functions of IKKβ

Dulce Maroni, Sandeep Rana, Chandrani Mukhopadhyay, Amarnath Natarajan, Mayumi Naramura

Immunol Lett. Author manuscript; available in PMC 2016 Dec 1.

Published in final edited form as: Immunol Lett. 2015 Dec; 168(2): 319–324. Published online 2015 Oct 27. doi: 10.1016/j.imlet.2015.10.011

PMCID:: PMC4688189

Article PDF–1.1M

Select item 46144526.

Anatomy of a negative feedback loop: the case of IκBα

Riku Fagerlund, Marcelo Behar, Karen T. Fortmann, Y. Eason Lin, Jesse D. Vargas, Alexander Hoffmann

J R Soc Interface. 2015 Sep 6; 12(110): 20150262. doi: 10.1098/rsif.2015.0262

PMCID:: PMC4614452

Article PDF–1.8M

Select item 41590767.

An IKKα-Nucleophosmin Axis Utilizes Inflammatory Signaling to Promote Genome Integrity

Xiaojun Xia, Shuang Liu, Zuoxiang Xiao, Feng Zhu, Na-Young Song, Ming Zhou, Bigang Liu, Jianjun Shen, Kunio Nagashima, Timothy D. Veenstra, Sandra Burkett, Mahesh Datla, Jami Willette-Brown, Haifa Shen, Yinling Hu

Cell Rep. Author manuscript; available in PMC 2014 Dec 12.

Published in final edited form as: Cell Rep. 2013 Dec 12; 5(5): 1243–1255. Published online 2013 Nov 27. doi: 10.1016/j.celrep.2013.10.046

PMCID:: PMC4159076

Article PDF–2.6M

Select item 38390588.

Knockdown of Intra-Islet IKKβ by Spherical Nucleic Acid Conjugates Prevents Cytokine-Induced Injury and Enhances Graft Survival

Jonathan S. Rink, Kaylin M. McMahon, Xiaomin Zhang, Xiaojuan Chen, Chad A. Mirkin, C. Shad Thaxton, Dixon B. Kaufman

Transplantation. Author manuscript; available in PMC 2014 Nov 27.

Published in final edited form as: Transplantation. 2013 Nov 27; 96(10): 10.1097/TP.0b013e3182a4190e. doi: 10.1097/TP.0b013e3182a4190e

PMCID:: PMC3839058

Article PDF–1.4M

Select item 37134249.

An IKKα–E2F1–BMI1 cascade activated by infiltrating B cells controls prostate regeneration and tumor recurrence

Massimo Ammirante, Ali I. Kuraishy, Shabnam Shalapour, Amy Strasner, Claudia Ramirez-Sanchez, Weizhou Zhang, Ahmed Shabaik, Michael Karin

Genes Dev. 2013 Jul 1; 27(13): 1435–1440. doi: 10.1101/gad.220202.113

PMCID:: PMC3713424

Article PDF–683K

Select item 370122210.

Inhibition of IκB kinase reduces the multiple organ dysfunction caused by sepsis in the mouse

Sina M. Coldewey, Mara Rogazzo, Massimo Collino, Nimesh S. A. Patel, Christoph Thiemermann

Dis Model Mech. 2013 Jul; 6(4): 1031–1042. Published online 2013 May 2. doi: 10.1242/dmm.012435

PMCID:: PMC3701222

Article

Select item 347325711.

IκBα deficiency in brain leads to elevated basal neuroinflammation and attenuated response following traumatic brain injury: implications for functional recovery

Hong Lian, David J Shim, Samson SK Gaddam, Jennifer Rodriguez-Rivera, Brittany R Bitner, Robia G Pautler, Claudia S Robertson, Hui Zheng

Mol Neurodegener. 2012; 7: 47. Published online 2012 Sep 19. doi: 10.1186/1750-1326-7-47

PMCID:: PMC3473257

Article PDF–2.9M

Select item 336968212.

IKKα-mediated signaling circuitry regulates early B lymphopoiesis during hematopoiesis

Mumtaz Yaseen Balkhi, Jami Willette-Brown, Feng Zhu, Zhisong Chen, Shuang Liu, Denis C. Guttridge, Michael Karin, Yinling Hu

Blood. 2012 Jun 7; 119(23): 5467–5477. Prepublished online 2012 Apr 27. doi: 10.1182/blood-2012-01-401547

PMCID:: PMC3369682

Article

Select item 321904113.

IκB Kinase Regulates Social Defeat Stress-Induced Synaptic and Behavioral Plasticity

Daniel J. Christoffel, Sam A. Golden, Dani Dumitriu, Alfred J. Robison, William G. Janssen, H. Francisca Ahn, Vaishnav Krishnan, Cindy M. Reyes, Ming-Hu Han, Jessica L. Ables, Amelia J. Eisch, David M. Dietz, Deveroux Ferguson, Rachael L. Neve, Paul Greengard, Yong Kim, John H. Morrison, Scott J. Russo

J Neurosci. 2011 Jan 5; 31(1): 314–321. doi: 10.1523/JNEUROSCI.4763-10.2011

PMCID:: PMC3219041

Article PDF–1.5M

Select item 321490914.

IKKα represses a network of inflammation and proliferation pathways and elevates c-Myc antagonists and differentiation in a dose-dependent manner in the skin

B Liu, J Willette-Brown, S Liu, X Chen, S M Fischer, Y Hu

Cell Death Differ. 2011 Dec; 18(12): 1854–1864. Published online 2011 May 13. doi: 10.1038/cdd.2011.56

PMCID:: PMC3214909

Article PDF–1.0M

Select item 313533815.

Transcriptional regulation of the Th17 immune response by IKKα

Li Li, Qingguo Ruan, Brendan Hilliard, Jennifer DeVirgiliis, Michael Karin, Youhai H. Chen

J Exp Med. 2011 Apr 11; 208(4): 787–796. doi: 10.1084/jem.20091346

PMCID:: PMC3135338

Article PDF–2.1M

Select item 239624816.

IKKα Causes Chromatin Modification on Pro-Inflammatory Genes by Cigarette Smoke in Mouse Lung

Se-Ran Yang, Samantha Valvo, Hongwei Yao, Aruna Kode, Saravanan Rajendrasozhan, Indika Edirisinghe, Samuel Caito, David Adenuga, Ryan Henry, George Fromm, Sanjay Maggirwar, Jian-Dong Li, Michael Bulger, Irfan Rahman

Am J Respir Cell Mol Biol. 2008 Jun; 38(6): 689–698. Published online 2008 Jan 31. doi: 10.1165/rcmb.2007-0379OC

PMCID:: PMC2396248

Article PDF–1.0M

Select item 236142317.

Nuclear Factor-κB Activation in Airway Epithelium Induces Inflammation and Hyperresponsiveness

Cristen Pantano, Jennifer L. Ather, John F. Alcorn, Matthew E. Poynter, Amy L. Brown, Amy S. Guala, Stacie L. Beuschel, Gilman B. Allen, Laurie A. Whittaker, Mieke Bevelander, Charles G. Irvin, Yvonne M. W. Janssen-Heininger

Am J Respir Crit Care Med. 2008 May 1; 177(9): 959–969. Published online 2008 Feb 8. doi: 10.1164/rccm.200707-1096OC