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Items: 1 to 20 of 37

1.
Intestinal Phospholipid Disequilibrium Initiates an ER Stress Response That Drives Goblet Cell Necroptosis and Spontaneous Colitis in Mice
John P. Kennelly, Stephanie Carlin, Tingting Ju, Jelske N. van der Veen, Randal C. Nelson, Jean Buteau, Aducio Thiesen, Caroline Richard, Ben P. Willing, René L. Jacobs
Cell Mol Gastroenterol Hepatol. 2021; 11(4): 999–1021. Published online 2020 Nov 22. doi: 10.1016/j.jcmgh.2020.11.006
PMCID:
PMC7898069
AbstractArticlePDF–5.2M
2.
Intestinal de novo phosphatidylcholine synthesis is required for dietary lipid absorption and metabolic homeostasis
John P. Kennelly, Jelske N. van der Veen, Randal C. Nelson, Kelly-Ann Leonard, Rick Havinga, Jean Buteau, Folkert Kuipers, René L. Jacobs
J Lipid Res. 2018 Sep; 59(9): 1695–1708. Published online 2018 Jul 14. doi: 10.1194/jlr.M087056
PMCID:
PMC6121921
AbstractArticlePDF–1.8M
3.
Transcriptional Regulation of Lung Cytidylyltransferase in Developing Transgenic Mice
Diann M. McCoy, Kurt Fisher, John Robichaud, Alan J. Ryan, Rama K. Mallampalli
Am J Respir Cell Mol Biol. 2006 Sep; 35(3): 394–402. Published online 2006 Apr 27. doi: 10.1165/rcmb.2005-0401OC
PMCID:
PMC2643291
AbstractArticlePDF–441K
4.
15-Deoxy-Δ12,14-prostaglandin J2 Impairs Phosphatidylcholine Synthesis and Induces Nuclear Accumulation of Thiol-modified Cytidylyltransferase
Alan J. Ryan, Bill B. Chen, Prashanth R. Vennalaganti, Florita C. Henderson, Linda A. Tephly, A. Brent Carter, Rama K. Mallampalli
J Biol Chem. 2008 Sep 5; 283(36): 24628–24640. doi: 10.1074/jbc.M801167200
PMCID:
PMC2529000
AbstractArticlePDF–939K
5.
Role of Phosphocholine Cytidylyltransferase α in Lung Development
Yong Tian, Ruobing Zhou, Jerold E. Rehg, Suzanne Jackowski
Mol Cell Biol. 2007 Feb; 27(3): 975–982. Published online 2006 Nov 27. doi: 10.1128/MCB.01512-06
PMCID:
PMC1800673
AbstractArticlePDF–460K
6.
Palmitate induces cisternal ER expansion via the activation of XBP-1/CCTα-mediated phospholipid accumulation in RAW 264.7 cells
Seong Keun Kim, Eunhye Oh, Mihee Yun, Seong-Beom Lee, Gue Tae Chae
Lipids Health Dis. 2015; 14: 73. Published online 2015 Jul 16. doi: 10.1186/s12944-015-0077-3
PMCID:
PMC4502558
AbstractArticlePDF–2.0M
7.
The induction of a nucleoplasmic reticulum by prelamin A accumulation requires CTP:phosphocholine cytidylyltransferase-α
Chris N. Goulbourne, Ashraf N. Malhas, David J. Vaux
J Cell Sci. 2011 Dec 15; 124(24): 4253–4266. doi: 10.1242/jcs.091009
PMCID:
PMC3258109
AbstractArticle
8.
Phosphatidylcholine Biosynthesis during Neuronal Differentiation and Its Role in Cell Fate Determination
Hebe Marcucci, Luciana Paoletti, Suzanne Jackowski, Claudia Banchio
J Biol Chem. 2010 Aug 13; 285(33): 25382–25393. Published online 2010 Jun 5. doi: 10.1074/jbc.M110.139477
PMCID:
PMC2919101
AbstractArticlePDF–2.7M
9.
14-3-3ζ escorts CCTα for calcium-activated nuclear import in lung epithelia
Marianna Agassandian, Bill B. Chen, Christopher C. Schuster, Jon C. D. Houtman, Rama K. Mallampalli
FASEB J. 2010 Apr; 24(4): 1271–1283. doi: 10.1096/fj.09-136044
PMCID:
PMC2845428
AbstractArticle
10.
CTP:Phosphocholine Cytidylyltransferase α Is Required for B-cell Proliferation and Class Switch Recombination
Paolo Fagone, Christopher Gunter, Christopher R. Sage, Kathryn E. Gunn, Joseph W. Brewer, Suzanne Jackowski
J Biol Chem. 2009 Mar 13; 284(11): 6847–6854. doi: 10.1074/jbc.M807338200
PMCID:
PMC2652266
AbstractArticlePDF–575K
11.
Accelerated phosphatidylcholine turnover in macrophages promotes adipose tissue inflammation in obesity
Kasparas Petkevicius, Sam Virtue, Guillaume Bidault, Benjamin Jenkins, Cankut Çubuk, Cecilia Morgantini, Myriam Aouadi, Joaquin Dopazo, Mireille J Serlie, Albert Koulman, Antonio Vidal-Puig
eLife. 2019; 8: e47990. Published online 2019 Aug 16. doi: 10.7554/eLife.47990
PMCID:
PMC6748830
AbstractArticlePDF–2.3M
12.
Phosphatidylcholine as a metabolic cue for determining B cell fate and function
Joseph W. Brewer, Viktoriya Solodushko, Ileana Aragon, Robert A. Barrington
Cell Immunol. Author manuscript; available in PMC 2017 Dec 1.
Published in final edited form as: Cell Immunol. 2016 Dec; 310: 78–88. Published online 2016 Aug 3. doi: 10.1016/j.cellimm.2016.08.002
PMCID:
PMC5125835
AbstractArticlePDF–1.0M
13.
Phosphatidylcholine Synthesis for Lipid Droplet Expansion Is Mediated by Localized Activation of CTP:Phosphocholine Cytidylyltransferase
Natalie Krahmer, Yi Guo, Florian Wilfling, Maximiliane Hilger, Susanne Lingrell, Klaus Heger, Heather W. Newman, Marc Schmidt-Supprian, Dennis E. Vance, Matthias Mann, Robert V. Farese, Jr., Tobias C. Walther
Cell Metab. Author manuscript; available in PMC 2013 Aug 6.
Published in final edited form as: Cell Metab. 2011 Oct 5; 14(4): 504–515. doi: 10.1016/j.cmet.2011.07.013
PMCID:
PMC3735358
AbstractArticlePDF–1.7M
14.
Calcium-calmodulin kinase I cooperatively regulates nucleocytoplasmic shuttling of CCTα by accessing a nuclear export signal
Marianna Agassandian, Bill B. Chen, Roopa Pulijala, Leah Kaercher, Jennifer R. Glasser, Rama K. Mallampalli
Mol Biol Cell. 2012 Jul 15; 23(14): 2755–2769. doi: 10.1091/mbc.E11-10-0863
PMCID:
PMC3395663
AbstractArticlePDF–2.7M
15.
The Membrane Lipid Phosphatidylcholine Is an Unexpected Source of Triacylglycerol in the Liver
Jelske N. van der Veen, Susanne Lingrell, Dennis E. Vance
J Biol Chem. 2012 Jul 6; 287(28): 23418–23426. Published online 2012 May 18. doi: 10.1074/jbc.M112.381723
PMCID:
PMC3390618
AbstractArticlePDF–1.0M
16.
Masking of a Nuclear Signal Motif by Monoubiquitination Leads to Mislocalization and Degradation of the Regulatory Enzyme Cytidylyltransferase
Bill B. Chen, Rama K. Mallampalli
Mol Cell Biol. 2009 Jun; 29(11): 3062–3075. Published online 2009 Mar 30. doi: 10.1128/MCB.01824-08
PMCID:
PMC2682000
AbstractArticlePDF–3.4M
17.
Early Embryonic Lethality in Mice with Targeted Deletion of the CTP:Phosphocholine Cytidylyltransferase α Gene (Pcyt1a)
Limin Wang, Susan Magdaleno, Ira Tabas, Suzanne Jackowski
Mol Cell Biol. 2005 Apr; 25(8): 3357–3363. doi: 10.1128/MCB.25.8.3357-3363.2005
PMCID:
PMC1069620
AbstractArticlePDF–168K
18.
Metabolic control of Tfh cells and humoral immunity by phosphatidylethanolamine
Guotong Fu, Clifford S. Guy, Nicole M. Chapman, Gustavo Palacios, Jun Wei, Peipei Zhou, Lingyun Long, Yong-Dong Wang, Chenxi Qian, Yogesh Dhungana, Hongling Huang, Anil KC, Hao Shi, Sherri Rankin, Scott A. Brown, Amanda Johnson, Randall Wakefield, Camenzind G. Robinson, Xueyan Liu, Anthony Sheyn, Jiyang Yu, Suzanne Jackowski, Hongbo Chi
Nature. Author manuscript; available in PMC 2022 Jan 7.
Published in final edited form as: Nature. 2021 Jul; 595(7869): 724–729. Published online 2021 Jul 7. doi: 10.1038/s41586-021-03692-z
PMCID:
PMC8448202
AbstractArticlePDF–5.6M
19.
Lipid deprivation increases surfactant phosphatidylcholine synthesis via a sterol-sensitive regulatory element within the CTP:phosphocholine cytidylyltransferase promoter.
Rama K Mallampalli, Alan J Ryan, James L Carroll, Timothy F Osborne, Christie P Thomas
Biochem J. 2002 Feb 15; 362(Pt 1): 81–88. doi: 10.1042/0264-6021:3620081
PMCID:
PMC1222362
SummaryPDF–197K
20.
Calmodulin Antagonizes a Calcium-Activated SCF Ubiquitin E3 Ligase Subunit, FBXL2, To Regulate Surfactant Homeostasis
Bill B. Chen, Tiffany A. Coon, Jennifer R. Glasser, Rama K. Mallampalli
Mol Cell Biol. 2011 May; 31(9): 1905–1920. doi: 10.1128/MCB.00723-10
PMCID:
PMC3133224
AbstractArticlePDF–4.6M

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