PMC Links for Gene (Select 130399) - PMC

Select item 108633311.

Human ACVR1C missense variants that correlate with altered body fat distribution produce metabolic alterations of graded severity in knock-in mutant mice

Pawanrat Tangseefa, Hong Jin, Houyu Zhang, Meng Xie, Carlos F. Ibáñez

Mol Metab. 2024 Mar; 81: 101890. Published online 2024 Feb 1. doi: 10.1016/j.molmet.2024.101890

PMCID:: PMC10863331

Article PDF–3.3M

Select item 67135062.

A biomimetic pancreatic cancer on-chip reveals endothelial ablation via ALK7 signaling

Duc-Huy T. Nguyen, Esak Lee, Styliani Alimperti, Robert J. Norgard, Alec Wong, Jake June-Koo Lee, Jeroen Eyckmans, Ben Z. Stanger, Christopher S. Chen

Sci Adv. 2019 Aug; 5(8): eaav6789. Published online 2019 Aug 28. doi: 10.1126/sciadv.aav6789

PMCID:: PMC6713506

Article PDF–1.0M

Select item 39981493.

ALK7 Gene Polymorphism is Associated with Metabolic Syndrome Risk and Cardiovascular Remodeling

Wenchao Zhang, Hui Wang, Wei Zhang, Ruijuan Lv, Zhihao Wang, Yuanyuan Shang, Yun Zhang, Ming Zhong, Yuguo Chen, Mengxiong Tang

Arq Bras Cardiol. 2013 Aug; 101(2): 134–140. doi: 10.5935/abc.20130129

PMCID:: PMC3998149

Article PDF–275K

Select item 26810124.

ALK7 expression is specific for adipose tissue, reduced in obesity and correlates to factors implicated in metabolic disease

Lena M.S. Carlsson, Peter Jacobson, Andrew Walley, Philippe Froguel, Lars Sjöström, Per-Arne Svensson, Kajsa Sjöholm

Biochem Biophys Res Commun. 2009 May 1; 382(2): 309–314. doi: 10.1016/j.bbrc.2009.03.014

PMCID:: PMC2681012

Article

Select item 94937605.

Activin receptor-like kinase 7 silencing alleviates cardiomyocyte apoptosis, cardiac fibrosis, and dysfunction in diabetic rats

Lin Liu, Xin Zhou, Qiyu Zhang, Li Li, Yuanyuan Shang, Zhihao Wang, Ming Zhong, Yuguo Chen, Wei Zhang, Mengxiong Tang

Exp Biol Med (Maywood) 2022 Aug; 247(16): 1397–1409. Published online 2022 Jun 6. doi: 10.1177/15353702221095049

PMCID:: PMC9493760

Article PDF–3.6M

Select item 72001616.

Control of brown adipose tissue adaptation to nutrient stress by the activin receptor ALK7

Patricia Marmol, Favio Krapacher, Carlos F Ibáñez

eLife. 2020; 9: e54721. Published online 2020 May 5. doi: 10.7554/eLife.54721

PMCID:: PMC7200161

Article PDF–1.1M

Select item 3127477.

The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development

Eva Reissmann, Henrik Jörnvall, Andries Blokzijl, Olov Andersson, Chenbei Chang, Gabriella Minchiotti, M. Graziella Persico, Carlos F. Ibáñez, Ali H. Brivanlou

Genes Dev. 2001 Aug 1; 15(15): 2010–2022. doi: 10.1101/gad.201801

PMCID:: PMC312747

Article PDF–561K

Select item 64306938.

ACVR1C/SMAD2 signaling promotes invasion and growth in retinoblastoma

Laura Asnaghi, David T. White, Nolan Key, Joshua Choi, Alka Mahale, Hind Alkatan, Deepak P. Edward, Sahar M. Elkhamary, Saleh Al-Mesfer, Azza Maktabi, Christopher G. Hurtado, Grace Y. Lee, Angel M. Carcaboso, Jeff S. Mumm, Leen Abu Safieh, Charles G. Eberhart

Oncogene. Author manuscript; available in PMC 2019 May 6.

Published in final edited form as: Oncogene. 2019 Mar; 38(12): 2056–2075. Published online 2018 Nov 6. doi: 10.1038/s41388-018-0543-2

PMCID:: PMC6430693

Article PDF–2.5M

Select item 78655989.

UV-Induced Reduction of ACVR1C Decreases SREBP1 and ACC Expression by the Suppression of SMAD2 Phosphorylation in Normal Human Epidermal Keratinocytes

Yu-Dan Tian, Min Hwa Chung, Qing-Ling Quan, Dong Hun Lee, Eun Ju Kim, Jin Ho Chung

Int J Mol Sci. 2021 Feb; 22(3): 1101. Published online 2021 Jan 22. doi: 10.3390/ijms22031101

PMCID:: PMC7865598

Article PDF–2.1M

Select item 481495810.

NODAL secreted by male germ cells regulates the proliferation and function of human Sertoli cells from obstructive azoospermia and nonobstructive azoospermia patients

Ru-Hui Tian, Shi Yang, Zi-Jue Zhu, Jun-Long Wang, Yun Liu, Chencheng Yao, Meng Ma, Ying Guo, Qingqing Yuan, Yanan Hai, Yi-Ran Huang, Zuping He, Zheng Li

Asian J Androl. 2015 Nov-Dec; 17(6): 996–1005. Published online 2015 Aug 19. doi: 10.4103/1008-682X.159722

PMCID:: PMC4814958

Article PDF–3.8M

Select item 257515211.

Cyclin G2 Is Degraded through the Ubiquitin-Proteasome Pathway and Mediates the Antiproliferative Effect of Activin Receptor-like Kinase 7

Guoxiong Xu, Stefanie Bernaudo, Guodong Fu, Daniel Y. Lee, Burton B. Yang, Chun Peng

Mol Biol Cell. 2008 Nov; 19(11): 4968–4979. doi: 10.1091/mbc.E08-03-0259

PMCID:: PMC2575152

Article PDF–1.0M

Select item 243823612.

Growth/differentiation factor 3 signals through ALK7 and regulates accumulation of adipose tissue and diet-induced obesity

Olov Andersson, Marion Korach-Andre, Eva Reissmann, Carlos F. Ibáñez, Philippe Bertolino

Proc Natl Acad Sci U S A. 2008 May 20; 105(20): 7252–7256. Published online 2008 May 14. doi: 10.1073/pnas.0800272105

PMCID:: PMC2438236

Article PDF–1.3M

Select item 306993213.

Nodal Signals through Activin Receptor-Like Kinase 7 to Inhibit Trophoblast Migration and Invasion: Implication in the Pathogenesis of Preeclampsia

Lubna Nadeem, Sadia Munir, Guodong Fu, Caroline Dunk, Dora Baczyk, Isabella Caniggia, Stephen Lye, Chun Peng

Am J Pathol. 2011 Mar; 178(3): 1177–1189. doi: 10.1016/j.ajpath.2010.11.066

PMCID:: PMC3069932

Article PDF–3.3M

Select item 352727614.

A Synthetic Interaction Screen Identifies Factors Selectively Required for Proliferation and TERT Transcription in p53-Deficient Human Cancer Cells

Li Xie, Claude Gazin, Sung Mi Park, Lihua J. Zhu, Marie-anne Debily, Ellen L. W. Kittler, Maria L. Zapp, David Lapointe, Stephane Gobeil, Ching-Man Virbasius, Michael R. Green

PLoS Genet. 2012 Dec; 8(12): e1003151. Published online 2012 Dec 20. doi: 10.1371/journal.pgen.1003151

PMCID:: PMC3527276

Article PDF–1.8M

Select item 296729715.

A large-scale candidate-gene association study of age at menarche and age at natural menopause

Chunyan He, Peter Kraft, Daniel I. Chasman, Julie E. Buring, Constance Chen, Susan E. Hankinson, Guillaume Paré, Stephen Chanock, Paul M. Ridker, David J. Hunter

Hum Genet. Author manuscript; available in PMC 2010 Nov 1.

Published in final edited form as: Hum Genet. 2010 Nov; 128(5): 515–527. Published online 2010 Aug 24. doi: 10.1007/s00439-010-0878-4

PMCID:: PMC2967297

Article PDF–84K

Select item 389478616.

Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition

Mikko Taipale, Irina Krykbaeva, Martina Koeva, Can Kayatekin, Kenneth D. Westover, Georgios I. Karras, Susan Lindquist

Cell. Author manuscript; available in PMC 2014 Jan 17.

Published in final edited form as: Cell. 2012 Aug 31; 150(5): 987–1001. doi: 10.1016/j.cell.2012.06.047

PMCID:: PMC3894786

Article PDF–5.0M

Select item 816503017.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011