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Select item 105761331.

Endothelial deletion of EPH receptor A4 alters single-cell profile and Tie2/Akap12 signaling to preserve blood–brain barrier integrity

Alison Cash, Caroline de Jager, Thomas Brickler, Eman Soliman, Liliana Ladner, Alexandra M. Kaloss, Yumeng Zhu, Kevin J. Pridham, Jatia Mills, Jing Ju, Erwin Kristobal Gudenschwager Basso, Michael Chen, Zachary Johnson, Yianni Sotiropoulos, Xia Wang, Hehuang Xie, John B. Matson, Eric A. Marvin, Michelle H. Theus

Proc Natl Acad Sci U S A. 2023 Oct 10; 120(41): e2204700120. Published online 2023 Oct 5. doi: 10.1073/pnas.2204700120

PMCID:: PMC10576133

Article PDF–14M

Select item 96370642.

Altered thymocyte development observed in EphA4-deficient mice courses with changes in both thymic epithelial and extracellular matrix organization

Javier García-Ceca, Sara Montero-Herradón, Ana González, Rosa Plaza, Agustín G. Zapata

Cell Mol Life Sci. 2022; 79(11): 583. Published online 2022 Nov 5. doi: 10.1007/s00018-022-04610-w

PMCID:: PMC9637064

Article PDF–4.8M

Select item 90122773.

The Eph receptor A4 plays a role in demyelination and depression-related behavior

Yuan Li, Ping Su, Yuxiang Chen, Jing Nie, Ti-Fei Yuan, Albert H.C. Wong, Fang Liu

J Clin Invest. 2022 Apr 15; 132(8): e152187. Published online 2022 Apr 15. doi: 10.1172/JCI152187

Correction in:: J Clin Invest. 2022 May 16; 132(10): e161559.

PMCID:: PMC9012277

Article PDF–15M

Select item 76063664.

The EphA4 Signaling is Anti-Catabolic in Synoviocytes but Pro-Anabolic in Articular Chondrocytes

Virginia M. Stiffel, Alexander Thomas, Charles H. Rundle, Matilda H.-C. Sheng, Kin-Hing William Lau

Calcif Tissue Int. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: Calcif Tissue Int. 2020 Dec; 107(6): 576–592. Published online 2020 Aug 20. doi: 10.1007/s00223-020-00747-7

PMCID:: PMC7606366

Article PDF–3.0M

Select item 75158615.

Inducible EphA4 knockout causes motor deficits in young mice and is not protective in the SOD1^G93A mouse model of ALS

Sara L. Dominguez, Timothy Earr, Michelle Dourado, Hai Ngu, William J. Meilandt, Jesse E. Hanson

Sci Rep. 2020; 10: 15713. Published online 2020 Sep 24. doi: 10.1038/s41598-020-72723-y

PMCID:: PMC7515861

Article PDF–6.7M

Select item 74802476.

EphA4 Is Required for Neural Circuits Controlling Skilled Reaching

Juan Jiang, Klas Kullander, Bror Alstermark

J Neurosci. 2020 Sep 9; 40(37): 7091–7104. doi: 10.1523/JNEUROSCI.2892-19.2020

PMCID:: PMC7480247

Article PDF–5.1M

Select item 69095197.

EphA4 loss improves social memory performance and alters dendritic spine morphology without changes in amyloid pathology in a mouse model of Alzheimer’s disease

Lindsay Poppe, Laura Rué, Mieke Timmers, Annette Lenaerts, Annet Storm, Zsuzsanna Callaerts-Vegh, Gilles Courtand, Antina de Boer, Silke Smolders, Philip Van Damme, Ludo Van Den Bosch, Rudi D’Hooge, Bart De Strooper, Wim Robberecht, Robin Lemmens

Alzheimers Res Ther. 2019; 11: 102. Published online 2019 Dec 12. doi: 10.1186/s13195-019-0554-4

PMCID:: PMC6909519

Article PDF–4.2M

Select item 67737548.

Reducing EphA4 before disease onset does not affect survival in a mouse model of Amyotrophic Lateral Sclerosis

Laura Rué, Mieke Timmers, Annette Lenaerts, Silke Smolders, Lindsay Poppe, Antina de Boer, Ludo Van Den Bosch, Philip Van Damme, Wim Robberecht, Robin Lemmens

Sci Rep. 2019; 9: 14112. Published online 2019 Oct 1. doi: 10.1038/s41598-019-50615-0

PMCID:: PMC6773754

Article PDF–2.4M

Select item 66723849.

EphA4 Signaling Regulates Phospholipase Cγ1 Activation, Cofilin Membrane Association, and Dendritic Spine Morphology

Lei Zhou, Sarah J. Martinez, Michael Haber, Emma V. Jones, David Bouvier, Guy Doucet, Amadou T. Corera, Edward A. Fon, Andreas H. Zisch, Keith K. Murai

J Neurosci. 2007 May 9; 27(19): 5127–5138. doi: 10.1523/JNEUROSCI.1170-07.2007

PMCID:: PMC6672384

Article PDF–751K

Select item 642903110.

Critical role of EphA4 in early brain injury after subarachnoid hemorrhage in rat

Ruiming Fan, Budbazar Enkhjargal, Richard Camara, Feng Yan, Lei Gong, Shengtao Yao, Jiping Tang, Yangmei Chen, John H. Zhang

Exp Neurol. Author manuscript; available in PMC 2019 Mar 22.

Published in final edited form as: Exp Neurol. 2017 Oct; 296: 41–48. Published online 2017 Jul 8. doi: 10.1016/j.expneurol.2017.07.003

PMCID:: PMC6429031

Article PDF–1.3M

Select item 535565011.

EphA4 may contribute to microvessel remodeling in the hippocampal CA1 and CA3 areas in a mouse model of temporal lobe epilepsy

Li Feng, Yi Shu, Qian Wu, Tiantian Liu, Hongyu Long, Huan Yang, Yi Li, Bo Xiao

Mol Med Rep. 2017 Jan; 15(1): 37–46. Published online 2016 Dec 9. doi: 10.3892/mmr.2016.6017

PMCID:: PMC5355650

Article PDF–2.9M

Select item 410331812.

Blockade of EphA4 signaling ameliorates hippocampal synaptic dysfunctions in mouse models of Alzheimer’s disease

Amy K. Y. Fu, Kwok-Wang Hung, Huiqian Huang, Shuo Gu, Yang Shen, Elaine Y. L. Cheng, Fanny C. F. Ip, Xuhui Huang, Wing-Yu Fu, Nancy Y. Ip

Proc Natl Acad Sci U S A. 2014 Jul 8; 111(27): 9959–9964. Published online 2014 Jun 23. doi: 10.1073/pnas.1405803111

PMCID:: PMC4103318

Article PDF–1.2M

Select item 356363213.

EphA4 Receptor Tyrosine Kinase Is a Modulator of Onset and Disease Severity of Experimental Autoimmune Encephalomyelitis (EAE)

Kathryn M. Munro, Kirsty J. Dixon, Melissa M. Gresle, Anna Jonas, Dennis Kemper, William Doherty, Louis J. Fabri, Catherine M. Owczarek, Martin Pearse, Andrew W. Boyd, Trevor J. Kilpatrick, Helmut Butzkueven, Ann M. Turnley

PLoS One. 2013; 8(2): e55948. Published online 2013 Feb 4. doi: 10.1371/journal.pone.0055948

PMCID:: PMC3563632

Article PDF–2.5M

Select item 335826414.

Differential Gene Expression in the EphA4 Knockout Spinal Cord and Analysis of the Inflammatory Response Following Spinal Cord Injury

Kathryn M. Munro, Victoria M. Perreau, Ann M. Turnley

PLoS One. 2012; 7(5): e37635. Published online 2012 May 22. doi: 10.1371/journal.pone.0037635

PMCID:: PMC3358264

Article PDF–3.6M

Select item 310024115.

EphA4 expression promotes network activity and spine maturation in cortical neuronal cultures

Meredith A Clifford, Jessleen K Kanwal, Rhonda Dzakpasu, Maria J Donoghue

Neural Dev. 2011; 6: 21. Published online 2011 May 4. doi: 10.1186/1749-8104-6-21

PMCID:: PMC3100241

Article PDF–1.1M

Select item 281960516.

Generation of an EphA4 conditional allele in mice

Julia E. Herrmann, Morgan A. Pence, Emanuel A. Shapera, Ravi R. Shah, Cédric G. Geoffroy, Binhai Zheng

Genesis. Author manuscript; available in PMC 2011 Feb 1.

Published in final edited form as: Genesis. 2010 Feb; 48(2): 101–105. doi: 10.1002/dvg.20587

PMCID:: PMC2819605

Article PDF–322K

Select item 162287317.

Eph tyrosine kinase receptor EphA4 is required for the topographic mapping of the corticospinal tract

Alison J. Canty, Ursula Greferath, Ann M. Turnley, Mark Murphy

Proc Natl Acad Sci U S A. 2006 Oct 17; 103(42): 15629–15634. Published online 2006 Oct 9. doi: 10.1073/pnas.0607350103

PMCID:: PMC1622873

Article PDF–566K

Select item 123653518.

EphA4 defines a class of excitatory locomotor-related interneurons

Simon J. B. Butt, Line Lundfald, Ole Kiehn

Proc Natl Acad Sci U S A. 2005 Sep 27; 102(39): 14098–14103. Published online 2005 Sep 19. doi: 10.1073/pnas.0503317102

PMCID:: PMC1236535

Article PDF–442K

Select item 882007419.

Antisense-Mediated Reduction of EphA4 in the Adult CNS Does Not Improve the Function of Mice with Amyotrophic Lateral Sclerosis

Karen K. Ling, Michaela Jackson, Duah Alkam, Dawei Liu, Norm Allaire, Chao Sun, Mahmoud Kiaei, Alexander McCampbell, Frank Rigo

Neurobiol Dis. Author manuscript; available in PMC 2022 Feb 7.

Published in final edited form as: Neurobiol Dis. 2018 Jun; 114: 174–183. Published online 2018 Mar 6. doi: 10.1016/j.nbd.2018.03.002

PMCID:: PMC8820074

Article PDF–1.6M

Select item 849774620.

Conditional Deletion of EphA4 on Cx3cr1-Expressing Microglia Fails to Influence Histopathological Outcome and Blood Brain Barrier Disruption Following Brain Injury

Eman Soliman, Jatia Mills, Jing Ju, Alexandra M. Kaloss, Erwin Kristobal Gudenschwager Basso, Nathalie Groot, Colin Kelly, Elizabeth A. Kowalski, Mohamed Elhassanny, Michael Chen, Xia Wang, Michelle H. Theus

Front Mol Neurosci. 2021; 14: 747770. Published online 2021 Sep 24. doi: 10.3389/fnmol.2021.747770