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Select item 92709721.

Uncoupling transcription and translation through miRNA-dependent poly(A) length control in haploid male germ cells

Mei Guo, Chunhai Luo, Zhuqing Wang, Sheng Chen, Dayton Morris, Fengying Ruan, Zhichao Chen, Linfeng Yang, Xiongyi Wei, Chuanwen Wu, Bei Luo, Zhou Lv, Jin Huang, Dong Zhang, Cong Yu, Qiang Gao, Hongqi Wang, Ying Zhang, Fei Sun, Wei Yan, Chong Tang

Development. 2022 Jun 15; 149(12): dev199573. Published online 2022 Jun 16. doi: 10.1242/dev.199573

PMCID:: PMC9270972

Article

Select item 80121032.

Control of ribosomal protein synthesis by the Microprocessor complex

Xuan Jiang, Amit Prabhakar, Stephanie M. Van der Voorn, Prajakta Ghatpande, Barbara Celona, Srivats Venkataramanan, Lorenzo Calviello, Chuwen Lin, Wanpeng Wang, Brian L. Black, Stephen N. Floor, Giorgio Lagna, Akiko Hata

Sci Signal. Author manuscript; available in PMC 2021 Aug 23.

Published in final edited form as: Sci Signal. 2021 Feb 23; 14(671): eabd2639. Published online 2021 Feb 23. doi: 10.1126/scisignal.abd2639

PMCID:: PMC8012103

Article PDF–3.1M

Select item 59921963.

Loss of Drosha underlies dopaminergic neuron toxicity in models of Parkinson’s disease

Ronglin Wang, Fangfang Lu, Gang Zhu, Dayun Feng, Tiejian Nie, Kai Tao, Shaosong Yang, Jie Lei, Lu Huang, Zixu Mao, Qian Yang

Cell Death Dis. 2018 Jun; 9(6): 693. Published online 2018 Jun 7. doi: 10.1038/s41419-018-0716-5

PMCID:: PMC5992196

Article PDF–2.6M

Select item 57661574.

A novel requirement for DROSHA in maintenance of mammalian CG methylation

Athanasia Stathopoulou, Jyoti B. Chhetri, John C. Ambrose, Pierre-Olivier Estève, Lexiang Ji, Hediye Erdjument-Bromage, Guoqiang Zhang, Thomas A. Neubert, Sriharsa Pradhan, Javier Herrero, Robert J. Schmitz, Steen K.T. Ooi

Nucleic Acids Res. 2017 Sep 19; 45(16): 9398–9412. Published online 2017 Aug 3. doi: 10.1093/nar/gkx695

Correction in:: Nucleic Acids Res. 2017 Sep 19; 45(16): 9810.

PMCID:: PMC5766157

Article PDF–4.1M

Select item 27625195.

Alternative Processing of Primary microRNA Transcripts by Drosha Generates 5′ End Variation of Mature microRNA

Haoquan Wu, Chunting Ye, Danielle Ramirez, N. Manjunath

PLoS One. 2009; 4(10): e7566. Published online 2009 Oct 27. doi: 10.1371/journal.pone.0007566

PMCID:: PMC2762519

Article PDF–718K

Select item 82974446.

Global miRNA dosage control of embryonic germ layer specification

Yingzi Cui, Xuehui Lv, Li Ding, Lan Ke, Dechang Yang, Mehdi Pirouz, Ye Qi, Jennie Ong, Ge Gao, Peng Du, Richard I. Gregory

Nature. Author manuscript; available in PMC 2021 Nov 5.

Published in final edited form as: Nature. 2021 May; 593(7860): 602–606. Published online 2021 May 5. doi: 10.1038/s41586-021-03524-0

PMCID:: PMC8297444

Article PDF–5.2M

Select item 60638887.

Milk exosomes are bioavailable and distinct microRNA cargos have unique tissue distribution patterns

Sonia Manca, Bijaya Upadhyaya, Ezra Mutai, Amy T. Desaulniers, Rebecca A. Cederberg, Brett R. White, Janos Zempleni

Sci Rep. 2018; 8: 11321. Published online 2018 Jul 27. doi: 10.1038/s41598-018-29780-1

PMCID:: PMC6063888

Article PDF–6.7M

Select item 59625758.

Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophy

Inês do Carmo G. Gonçalves, Johanna Brecht, Maximilian P. Thelen, Wiebke A. Rehorst, Miriam Peters, Hyun Ju Lee, Susanne Motameny, Laura Torres-Benito, Darius Ebrahimi-Fakhari, Natalia L. Kononenko, Janine Altmüller, David Vilchez, Mustafa Sahin, Brunhilde Wirth, Min Jeong Kye

Sci Rep. 2018; 8: 7907. Published online 2018 May 21. doi: 10.1038/s41598-018-26347-y

Correction in:: Sci Rep. 2020; 10: 8206.

Correction in:: Sci Rep. 2018; 8: 10294.

PMCID:: PMC5962575

Article PDF–6.0M

Select item 54731389.

DROSHA targets its own transcript to modulate alternative splicing

Dooyoung Lee, Jin-Wu Nam, Chanseok Shin

RNA. 2017 Jul; 23(7): 1035–1047. doi: 10.1261/rna.059808.116

PMCID:: PMC5473138

Article PDF–526K

Select item 476032210.

Sperm-borne miRNAs and endo-siRNAs are important for fertilization and preimplantation embryonic development

Shuiqiao Yuan, Andrew Schuster, Chong Tang, Tian Yu, Nicole Ortogero, Jianqiang Bao, Huili Zheng, Wei Yan

Development. 2016 Feb 15; 143(4): 635–647. doi: 10.1242/dev.131755

PMCID:: PMC4760322

Article

Select item 443541511.

Murine Follicular Development Requires Oocyte DICER, but Not DROSHA

Shuiqiao Yuan, Nicole Ortogero, Qiuxia Wu, Huili Zheng, Wei Yan

Biol Reprod. 2014 Aug; 91(2): 39. Published online 2014 Jul 2. doi: 10.1095/biolreprod.114.119370

PMCID:: PMC4435415

Article PDF–676K

Select item 402487612.

Drosha as an interferon-independent antiviral factor

Jillian S. Shapiro, Sonja Schmid, Lauren C. Aguado, Leah R. Sabin, Ari Yasunaga, Jaehee V. Shim, David Sachs, Sara Cherry, Benjamin R. tenOever

Proc Natl Acad Sci U S A. 2014 May 13; 111(19): 7108–7113. Published online 2014 Apr 28. doi: 10.1073/pnas.1319635111

PMCID:: PMC4024876

Article PDF–1.0M

Select item 393476013.

Dynamic microRNA gene transcription and processing during T cell development

Francis F. Kirigin, Kenneth Lindstedt, Maclean Sellars, Maria Ciofani, Siao Li Low, Lachlan Jones, Fiona Bell, Florencia Pauli, Richard Bonneau, Richard M. Myers, Dan R. Littman, Mark M.W. Chong

J Immunol. Author manuscript; available in PMC 2014 Feb 25.

Published in final edited form as: J Immunol. 2012 Apr 1; 188(7): 3257–3267. Published online 2012 Feb 29. doi: 10.4049/jimmunol.1103175

PMCID:: PMC3934760

Article PDF–676K

Select item 384479614.

Conditional Loss of Dicer Disrupts Cellular and Tissue Morphogenesis in the Cortex and Hippocampus

Tigwa H. Davis, Trinna L. Cuellar, Selina M. Koch, Allison J. Barker, Brian D. Harfe, Michael T. McManus, Erik M. Ullian

J Neurosci. 2008 Apr 23; 28(17): 4322–4330. doi: 10.1523/JNEUROSCI.4815-07.2008

PMCID:: PMC3844796

Article PDF–543K

Select item 324634715.

The Inducible Deletion of Drosha and MicroRNAs In Mature Podocytes Results In A Collapsing Glomerulopathy

Olga Zhdanova, Shekhar Srivastava, Lie Di, Zhai Li, Leila Tchelebi, Sara Dworkin, Duncan B Johnstone, Jiri Zavadil, Mark M. Chong, Dan R. Littman, Lawrence B. Holzman, Laura Barisoni, Edward Y. Skolnik

Kidney Int. Author manuscript; available in PMC 2012 Apr 1.

Published in final edited form as: Kidney Int. 2011 Oct; 80(7): 719–730. Published online 2011 May 4. doi: 10.1038/ki.2011.122

PMCID:: PMC3246347

Article PDF–3.8M

Select item 244199116.

A novel noncoding RNA processed by Drosha is restricted to nucleus in mouse

Gayatri Ganesan, Satyanarayana M.R. Rao

RNA. 2008 Jul; 14(7): 1399–1410. doi: 10.1261/rna.838308

PMCID:: PMC2441991

Article PDF–789K

Select item 211813417.

A role for Dicer in immune regulation

Bradley S. Cobb, Arnulf Hertweck, James Smith, Eric O'Connor, Daniel Graf, Terence Cook, Stephen T. Smale, Shimon Sakaguchi, Frederick J. Livesey, Amanda G. Fisher, Matthias Merkenschlager

J Exp Med. 2006 Oct 30; 203(11): 2519–2527. doi: 10.1084/jem.20061692

PMCID:: PMC2118134

Article PDF–1.3M

Select item 658563718.

The miRNA biogenesis pathway prevents inappropriate expression of injury response genes in developing and adult Schwann cells

Deniz Gökbuget, Jorge A. Pereira, Lennart Opitz, Dominik Christe, Tobias Kessler, Antonin Marchais, Ueli Suter

Glia. 2018 Dec; 66(12): 2632–2644. Published online 2018 Oct 8. doi: 10.1002/glia.23516

PMCID:: PMC6585637

Article PDF–7.5M

Select item 393409919.

The ARF tumor suppressor controls Drosha translation to prevent Ras-driven transformation

Michael J. Kuchenreuther, Jason D. Weber

Oncogene. Author manuscript; available in PMC 2014 Jul 16.

Published in final edited form as: Oncogene. 2014 Jan 16; 33(3): 300–307. Published online 2013 Jan 14. doi: 10.1038/onc.2012.601

PMCID:: PMC3934099

Article PDF–1.0M

Select item 340813320.

The RNase III Enzyme DROSHA Is Essential for MicroRNA Production and Spermatogenesis

Qiuxia Wu, Rui Song, Nicole Ortogero, Huili Zheng, Ryan Evanoff, Chris L. Small, Michael D. Griswold, Satoshi H. Namekawa, Helene Royo, James M. Turner, Wei Yan

J Biol Chem. 2012 Jul 20; 287(30): 25173–25190. Published online 2012 Jun 4. doi: 10.1074/jbc.M112.362053