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Select item 91973921.

Functional abnormalities in the cerebello-thalamic pathways in a mouse model of DYT25 dystonia

Hind Baba Aïssa, Romain W Sala, Elena Laura Georgescu Margarint, Jimena Laura Frontera, Andrés Pablo Varani, Fabien Menardy, Assunta Pelosi, Denis Hervé, Clément Léna, Daniela Popa

eLife. 2022; 11: e79135. Published online 2022 Jun 14. doi: 10.7554/eLife.79135

PMCID:: PMC9197392

Abstract Article PDF–1.7M

Select item 79624782.

Gnal haploinsufficiency causes genomic instability and increased sensitivity to haloperidol

Mohammad Moshahid Khan, Jianfeng Xiao, T.J. Hollingsworth, Damini Patel, Dana E. Selley, Trevor L. Ring, Mark S. LeDoux

Exp Neurol. Author manuscript; available in PMC 2021 Mar 16.

Published in final edited form as: Exp Neurol. 2019 Aug; 318: 61–70. Published online 2019 Apr 26. doi: 10.1016/j.expneurol.2019.04.014

PMCID:: PMC7962478

Abstract Article PDF–1.7M

Select item 67726083.

G_OLFα Mediates Dopamine D₁ Receptor Signaling

Xiaoxi Zhuang, Leonardo Belluscio, Rene Hen

J Neurosci. 2000 Aug 15; 20(16): RC91. doi: 10.1523/JNEUROSCI.20-16-j0001.2000

PMCID:: PMC6772608

Abstract PDF–190K

Select item 67057004.

Heterozygous Gnal Mice Are a Novel Animal Model with Which to Study Dystonia Pathophysiology

Assunta Pelosi, Fabien Menardy, Daniela Popa, Jean-Antoine Girault, Denis Hervé

J Neurosci. 2017 Jun 28; 37(26): 6253–6267. doi: 10.1523/JNEUROSCI.1529-16.2017

PMCID:: PMC6705700

Abstract Article PDF–10M

Select item 30210435.

Unitary response of mouse olfactory receptor neurons

Yair Ben-Chaim, Melody M. Cheng, King-Wai Yau

Proc Natl Acad Sci U S A. 2011 Jan 11; 108(2): 822–827. Published online 2010 Dec 27. doi: 10.1073/pnas.1017983108

PMCID:: PMC3021043

Abstract Article PDF–571K

Select item 67335436.

Diverse Mechanisms Lead to Common Dysfunction of Striatal Cholinergic Interneurons in Distinct Genetic Mouse Models of Dystonia

Karen L. Eskow Jaunarajs, Mariangela Scarduzio, Michelle E. Ehrlich, Lori L. McMahon, David G. Standaert

J Neurosci. 2019 Sep 4; 39(36): 7195–7205. doi: 10.1523/JNEUROSCI.0407-19.2019

PMCID:: PMC6733543

Abstract Article PDF–611K

Select item 67249357.

Ric-8B, an Olfactory Putative GTP Exchange Factor, Amplifies Signal Transduction through the Olfactory-Specific G-Protein Gαolf

Luiz Eduardo C. Von Dannecker, Adriana F. Mercadante, Bettina Malnic

J Neurosci. 2005 Apr 13; 25(15): 3793–3800. doi: 10.1523/JNEUROSCI.4595-04.2005

PMCID:: PMC6724935

Abstract Article PDF–444K

Select item 67036208.

Gα_olf Mutation Allows Parsing the Role of cAMP-Dependent and Extracellular Signal-Regulated Kinase-Dependent Signaling in l-3,4-Dihydroxyphenylalanine-Induced Dyskinesia

Cristina Alcacer, Emanuela Santini, Emmanuel Valjent, Florence Gaven, Jean-Antoine Girault, Denis Hervé

J Neurosci. 2012 Apr 25; 32(17): 5900–5910. doi: 10.1523/JNEUROSCI.0837-12.2012

PMCID:: PMC6703620

Abstract Article PDF–1.5M

Select item 37172239.

Striatal neurones have a specific ability to respond to phasic dopamine release

Liliana R V Castro, Marina Brito, Elvire Guiot, Marina Polito, Christoph W Korn, Denis Hervé, Jean-Antoine Girault, Danièle Paupardin-Tritsch, Pierre Vincent

J Physiol. 2013 Jul 1; 591(Pt 13): 3197–3214. Published online 2013 Apr 3. doi: 10.1113/jphysiol.2013.252197

PMCID:: PMC3717223

Abstract Article PDF–1.6M

Select item 555952810.

The BEACH Protein LRBA Promotes the Localization of the Heterotrimeric G-protein G_olf to Olfactory Cilia

Stefan Kurtenbach, Andreas Gießl, Siv Strömberg, Jan Kremers, Jenny Atorf, Sebastian Rasche, Eva M. Neuhaus, Denis Hervé, Johann Helmut Brandstätter, Esther Asan, Hanns Hatt, Manfred W. Kilimann

Sci Rep. 2017; 7: 8409. Published online 2017 Aug 16. doi: 10.1038/s41598-017-08543-4

PMCID:: PMC5559528

Abstract Article PDF–4.9M

Select item 319408211.

Haloperidol Regulates the State of Phosphorylation of Ribosomal Protein S6 via Activation of PKA and Phosphorylation of DARPP-32

Emmanuel Valjent, Jesus Bertran-Gonzalez, Heather Bowling, Sébastien Lopez, Emanuela Santini, Miriam Matamales, Alessandra Bonito-Oliva, Denis Hervé, Charles Hoeffer, Eric Klann, Jean-Antoine Girault, Gilberto Fisone

Neuropsychopharmacology. 2011 Nov; 36(12): 2561–2570. Published online 2011 Aug 3. doi: 10.1038/npp.2011.144

PMCID:: PMC3194082

Abstract Article PDF–672K

Select item 294327312.

Adenosine A_2A Receptor Signaling and G_olf Assembly Show a Specific Requirement for the γ₇ Subtype in the Striatum

William F. Schwindinger, Lauren J. Murphree Mihalcik, Kathryn E. Giger, Kelly S. Betz, Anna Maria Stauffer, Joel Linden, Denis Herve, Janet D. Robishaw

J Biol Chem. 2010 Sep 24; 285(39): 29787–29796. Published online 2010 Jul 16. doi: 10.1074/jbc.M110.142620

PMCID:: PMC2943273

Abstract Article PDF–1.9M

Select item 275856113.

Histone H3 phosphorylation is under the opposite tonic control of dopamine D2 and adenosine A2A receptors in striatopallidal neurons

Jesus Bertran-Gonzalez, Kerstin Håkansson, Anders Borgkvist, Theano Irinopoulou, Karen Brami-Cherrier, Alessandro Usiello, Paul Greengard, Denis Hervé, Jean-Antoine Girault, Emmanuel Valjent, Gilberto Fisone

Neuropsychopharmacology. Author manuscript; available in PMC 2009 Oct 7.

Published in final edited form as: Neuropsychopharmacology. 2009 Jun; 34(7): 1710–1720. Published online 2009 Jan 21. doi: 10.1038/npp.2008.228

PMCID:: PMC2758561

Abstract Article PDF–3.9M

Select item 660529514.

PKA-Dependent Phosphorylation of Ribosomal Protein S6 Does Not Correlate with Translation Efficiency in Striatonigral and Striatopallidal Medium-Sized Spiny Neurons

Anne Biever, Emma Puighermanal, Akinori Nishi, Alexandre David, Claire Panciatici, Sophie Longueville, Dimitris Xirodimas, Giuseppe Gangarossa, Oded Meyuhas, Denis Hervé, Jean-Antoine Girault, Emmanuel Valjent

J Neurosci. 2015 Mar 11; 35(10): 4113–4130. doi: 10.1523/JNEUROSCI.3288-14.2015

PMCID:: PMC6605295

Abstract Article PDF–8.4M

Select item 302469715.

Genetic susceptibility to systemic lupus erythematosus protects against cerebral malaria in mice

Michael Waisberg, Tatyana Tarasenko, Brandi K. Vickers, Bethany L. Scott, Lisa C. Willcocks, Alvaro Molina-Cruz, Matthew A. Pierce, Chiung-yu Huang, Fernando J. Torres-Velez, Kenneth G. C. Smith, Carolina Barillas-Mury, Louis H. Miller, Susan K. Pierce, Silvia Bolland

Proc Natl Acad Sci U S A. 2011 Jan 18; 108(3): 1122–1127. Published online 2010 Dec 27. doi: 10.1073/pnas.1017996108

PMCID:: PMC3024697

Abstract Article PDF–1.2M

Select item 739403716.

Agonist-Independent GPCR Activity Regulates Anterior-Posterior Targeting of Olfactory Sensory Neurons

Ai Nakashima, Haruki Takeuchi, Takeshi Imai, Harumi Saito, Hiroshi Kiyonari, Takaya Abe, Min Chen, Lee S. Weinstein, C. Ron Yu, Daniel R. Storm, Hirofumi Nishizumi, Hitoshi Sakano

Cell. Author manuscript; available in PMC 2020 Jul 31.

Published in final edited form as: Cell. 2013 Sep 12; 154(6): 1314–1325. doi: 10.1016/j.cell.2013.08.033

PMCID:: PMC7394037

Abstract Article PDF–2.3M

Select item 472812617.

Stable G protein-effector complexes in striatal neurons: mechanism of assembly and role in neurotransmitter signaling

Keqiang Xie, Ikuo Masuho, Chien-Cheng Shih, Yan Cao, Keita Sasaki, Chun Wan J Lai, Pyung-Lim Han, Hiroshi Ueda, Carmen W Dessauer, Michelle E Ehrlich, Baoji Xu, Barry M Willardson, Kirill A Martemyanov

eLife. 2015; 4: e10451. Published online 2015 Nov 27. doi: 10.7554/eLife.10451

PMCID:: PMC4728126

Abstract Article PDF–3.1M

Select item 676274918.

Gα_olf Levels Are Regulated by Receptor Usage and Control Dopamine and Adenosine Action in the Striatum

Denis Hervé, Catherine Le Moine, Jean-Christophe Corvol, Leonardo Belluscio, Catherine Ledent, Allen A. Fienberg, Mohamed Jaber, Jeanne-Marie Studler, Jean-Antoine Girault

J Neurosci. 2001 Jun 15; 21(12): 4390–4399. doi: 10.1523/JNEUROSCI.21-12-04390.2001

PMCID:: PMC6762749

Abstract Article PDF–1.0M

Select item 475796519.

Abnormalities of motor function, transcription and cerebellar structure in mouse models of THAP1 dystonia

Marta Ruiz, Georgina Perez-Garcia, Maitane Ortiz-Virumbrales, Aurelie Méneret, Andrika Morant, Jessica Kottwitz, Tania Fuchs, Justine Bonet, Pedro Gonzalez-Alegre, Patrick R. Hof, Laurie J. Ozelius, Michelle E. Ehrlich

Hum Mol Genet. 2015 Dec 20; 24(25): 7159–7170. Published online 2015 Sep 16. doi: 10.1093/hmg/ddv384