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Select item 101591651.

Diurnal regulation of metabolism by G_s-alpha in hypothalamic QPLOT neurons

Kevin D. Gaitonde, Mutahar Andrabi, Courtney A. Burger, Shane P. D’Souza, Shruti Vemaraju, Bala S. C. Koritala, David F. Smith, Richard A. Lang

PLoS One. 2023; 18(5): e0284824. Published online 2023 May 4. doi: 10.1371/journal.pone.0284824

PMCID:: PMC10159165

Article PDF–3.9M

Select item 93581402.

Endothelial G protein stimulatory α-subunit is a critical regulator of post-ischemic angiogenesis

Lifan He, Hanlin Lu, Jianying Chu, Xiaoteng Qin, Jiangang Gao, Min Chen, Lee S. Weinstein, Jianmin Yang, Qunye Zhang, Cheng Zhang, Wencheng Zhang

Front Cardiovasc Med. 2022; 9: 941946. Published online 2022 Jul 25. doi: 10.3389/fcvm.2022.941946

PMCID:: PMC9358140

Article PDF–5.6M

Select item 92663563.

Gnas Loss Causes Chondrocyte Fate Conversion in Cranial Suture Formation

R. Xu, Y. Liu, Y. Zhou, W. Lin, Q. Yuan, X. Zhou, Y. Yang

J Dent Res. 2022 Jul; 101(8): 931–941. Published online 2022 Feb 26. doi: 10.1177/00220345221075215

PMCID:: PMC9266356

Article PDF–3.3M

Select item 89778384.

PDE4B Is a Homeostatic Regulator of Cyclic AMP in Dendritic Cells

Amy M. Chinn, Cristina Salmerón, Jihyung Lee, Krishna Sriram, Eyal Raz, Paul A. Insel

Front Pharmacol. 2022; 13: 833832. Published online 2022 Mar 21. doi: 10.3389/fphar.2022.833832

PMCID:: PMC8977838

Article PDF–1.5M

Select item 87710025.

Parental Origin of Gsα Inactivation Differentially Affects Bone Remodeling in a Mouse Model of Albright Hereditary Osteodystrophy

Patrick McMullan, Peter Maye, Qingfen Yang, David W. Rowe, Emily L. Germain‐Lee

JBMR Plus. 2022 Jan; 6(1): e10570. Published online 2021 Nov 16. doi: 10.1002/jbm4.10570

PMCID:: PMC8771002

Article PDF–11M

Select item 81219626.

Role of mTORC2 in biphasic regulation of brown fat metabolism in response to mild and severe cold

Prasanna K.R. Allu, Esther Paulo, Ambre M. Bertholet, Gavin Situ, Seung-Hwan Lee, Yixuan Wu, Catherine E. Gleason, Bidisha Saha, Ajay Chawla, Biao Wang, David Pearce

J Biol Chem. 2021 Jan-Jun; 296: 100632. Published online 2021 Apr 15. doi: 10.1016/j.jbc.2021.100632

PMCID:: PMC8121962

Article PDF–1.9M

Select item 76764277.

Control of Adipocyte Thermogenesis and Lipogenesis through γ3-Adrenergic and Thyroid Hormone Signal Integration

Adilson Guilherme, Batuhan Yenilmez, Alexander H. Bedard, Felipe Henriques, Dianxin Liu, Alexandra Lee, Lauren Goldstein, Mark Kelly, Sarah M. Nicoloro, Min Chen, Lee Weinstein, Sheila Collins, Michael P. Czech

Cell Rep. Author manuscript; available in PMC 2020 Nov 19.

Published in final edited form as: Cell Rep. 2020 May 5; 31(5): 107598. doi: 10.1016/j.celrep.2020.107598

PMCID:: PMC7676427

Article PDF–1.4M

Select item 66053148.

Neuromodulatory Effect of Gα_s- or Gα_q-Coupled G-Protein-Coupled Receptor on NMDA Receptor Selectively Activates the NMDA Receptor/Ca²⁺/Calcineurin/cAMP Response Element-Binding Protein-Regulated Transcriptional Coactivator 1 Pathway to Effectively Induce Brain-Derived Neurotrophic Factor Expression in Neurons

Mamoru Fukuchi, Akiko Tabuchi, Yuki Kuwana, Shinjiro Watanabe, Minami Inoue, Ichiro Takasaki, Hironori Izumi, Ayumi Tanaka, Ran Inoue, Hisashi Mori, Hidetoshi Komatsu, Hiroshi Takemori, Hiroyuki Okuno, Haruhiko Bito, Masaaki Tsuda

J Neurosci. 2015 Apr 8; 35(14): 5606–5624. doi: 10.1523/JNEUROSCI.3650-14.2015

PMCID:: PMC6605314

Article PDF–6.7M

Select item 57769789.

Induced Gnas^R201H expression from the endogenous Gnas locus causes fibrous dysplasia by up-regulating Wnt/β-catenin signaling

Sanjoy Kumar Khan, Prem Swaroop Yadav, Gene Elliott, Dorothy Zhang Hu, Ruoshi Xu, Yingzi Yang

Proc Natl Acad Sci U S A. 2018 Jan 16; 115(3): E418–E427. Published online 2017 Nov 20. doi: 10.1073/pnas.1714313114

PMCID:: PMC5776978

Article PDF–2.4M

Select item 569807310.

Interference with Gsα-Coupled Receptor Signaling in Renin-Producing Cells Leads to Renal Endothelial Damage

Peter Lachmann, Linda Hickmann, Anne Steglich, Moath Al-Mekhlafi, Michael Gerlach, Niels Jetschin, Steffen Jahn, Brigitte Hamann, Monika Wnuk, Kirsten Madsen, Valentin Djonov, Min Chen, Lee S. Weinstein, Bernd Hohenstein, Christian P.M. Hugo, Vladimir T. Todorov

J Am Soc Nephrol. 2017 Dec; 28(12): 3479–3489. Published online 2017 Aug 3. doi: 10.1681/ASN.2017020173

PMCID:: PMC5698073

Article

Select item 569258111.

Large G protein α-subunit XLαs limits clathrin-mediated endocytosis and regulates tissue iron levels in vivo

Qing He, Richard Bouley, Zun Liu, Marc N. Wein, Yan Zhu, Jordan M. Spatz, Chia-Yu Wang, Paola Divieti Pajevic, Antonius Plagge, Jodie L. Babitt, Murat Bastepe

Proc Natl Acad Sci U S A. 2017 Nov 7; 114(45): E9559–E9568. Published online 2017 Oct 23. doi: 10.1073/pnas.1712670114

PMCID:: PMC5692581

Article PDF–2.1M

Select item 558534312.

Internalized TSH receptors en route to the TGN induce local G_s-protein signaling and gene transcription

Amod Godbole, Sandra Lyga, Martin J. Lohse, Davide Calebiro

Nat Commun. 2017; 8: 443. Published online 2017 Sep 5. doi: 10.1038/s41467-017-00357-2

Correction in:: Nat Commun. 2018; 9: 5459.

PMCID:: PMC5585343

Article PDF–5.7M

Select item 536453013.

Gsα Controls Cortical Bone Quality by Regulating Osteoclast Differentiation via cAMP/PKA and β-Catenin Pathways

Girish Ramaswamy, Hyunsoo Kim, Deyu Zhang, Vitali Lounev, Joy Y. Wu, Yongwon Choi, Frederick S. Kaplan, Robert J. Pignolo, Eileen M. Shore

Sci Rep. 2017; 7: 45140. Published online 2017 Mar 24. doi: 10.1038/srep45140

PMCID:: PMC5364530

Article PDF–1.5M

Select item 473312114.

G_sα Deficiency in the Ventromedial Hypothalamus Enhances Leptin Sensitivity and Improves Glucose Homeostasis in Mice on a High-Fat Diet

Alta Berger, Ahmed Kablan, Catherine Yao, Thuy Ho, Brandon Podyma, Lee S. Weinstein, Min Chen

Endocrinology. 2016 Feb; 157(2): 600–610. Published online 2015 Dec 15. doi: 10.1210/en.2015-1700

PMCID:: PMC4733121

Article

Select item 472244615.

Loss of G_sα in the Postnatal Skeleton Leads to Low Bone Mass and a Blunted Response to Anabolic Parathyroid Hormone Therapy

Partha Sinha, Piia Aarnisalo, Rhiannon Chubb, Ingrid J. Poulton, Jun Guo, Gregory Nachtrab, Takaharu Kimura, Srilatha Swami, Hamid Saeed, Min Chen, Lee S. Weinstein, Ernestina Schipani, Natalie A. Sims, Henry M. Kronenberg, Joy Y. Wu

J Biol Chem. 2016 Jan 22; 291(4): 1631–1642. Published online 2015 Nov 23. doi: 10.1074/jbc.M115.679753

PMCID:: PMC4722446

Article PDF–3.4M

Select item 472034816.

G_sα deficiency in adipose tissue improves glucose metabolism and insulin sensitivity without an effect on body weight

Yong-Qi Li, Yogendra B. Shrestha, Min Chen, Tatyana Chanturiya, Oksana Gavrilova, Lee S. Weinstein

Proc Natl Acad Sci U S A. 2016 Jan 12; 113(2): 446–451. Published online 2015 Dec 28. doi: 10.1073/pnas.1517142113

PMCID:: PMC4720348

Article PDF–1.1M

Select item 422350617.

Elevated blood pressure, heart rate and body temperature in mice lacking the XLαs protein of the Gnas locus is due to increased sympathetic tone

Nicolas Nunn, Claire H Feetham, Jennifer Martin, Richard Barrett-Jolley, Antonius Plagge

Exp Physiol. 2013 Oct 1; 98(10): 1432–1445. Published online 2013 Jun 7. doi: 10.1113/expphysiol.2013.073064

PMCID:: PMC4223506

Article PDF–1.3M

Select item 422054218.

Loss of G_sα Early in the Osteoblast Lineage Favors Adipogenic Differentiation of Mesenchymal Progenitors and Committed Osteoblast Precursors

Partha Sinha, Piia Aarnisalo, Rhiannon Chubb, Noriaki Ono, Keertik Fulzele, Martin Selig, Hamid Saeed, Min Chen, Lee S Weinstein, Paola Divieti Pajevic, Henry M Kronenberg, Joy Y Wu

J Bone Miner Res. Author manuscript; available in PMC 2014 Nov 5.

Published in final edited form as: J Bone Miner Res. 2014 Nov; 29(11): 2414–2426. doi: 10.1002/jbmr.2270

PMCID:: PMC4220542

Article PDF–1.8M

Select item 420527119.

Constitutive expression of Gsα^R201C in mice produces a heritable, direct replica of human fibrous dysplasia bone pathology and demonstrates its natural history

Isabella Saggio, Cristina Remoli, Emanuela Spica, Stefania Cersosimo, Benedetto Sacchetti, Pamela G. Robey, Kenn Holmbeck, Ana Cumano, Alan Boyde, Paolo Bianco, Mara Riminucci

J Bone Miner Res. Author manuscript; available in PMC 2015 Nov 1.

Published in final edited form as: J Bone Miner Res. 2014 Nov; 29(11): 2357–2368. doi: 10.1002/jbmr.2267

PMCID:: PMC4205271

Article PDF–4.7M

Select item 358457920.

Heterozygous inactivation of Gnas in adipose-derived mesenchymal progenitor cells enhances osteoblast differentiation and promotes heterotopic ossification

Robert J. Pignolo, Meiqi Xu, Elizabeth Russell, Alec Richardson, Josef Kaplan, Paul C. Billings, Frederick S. Kaplan, Eileen M. Shore

J Bone Miner Res. Author manuscript; available in PMC 2013 Feb 28.

Published in final edited form as: J Bone Miner Res. 2011 Nov; 26(11): 2647–2655. doi: 10.1002/jbmr.481

PMCID:: PMC3584579

Article PDF–3.0M

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