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Select item 87180901.

Skeletal muscle atrophy‐induced hemopexin accelerates onset of cognitive impairment in Alzheimer's disease

Tsukasa Nagase, Chihiro Tohda

J Cachexia Sarcopenia Muscle. 2021 Dec; 12(6): 2199–2210. Published online 2021 Oct 17. doi: 10.1002/jcsm.12830

PMCID:: PMC8718090

Abstract Article PDF–10M

Select item 58338472.

Plasma Hemopexin ameliorates murine spinal cord injury by switching microglia from the M1 state to the M2 state

Dunxin Han, Zhongwang Yu, Weili Liu, Dou Yin, Yingyan Pu, Jifeng Feng, Yimin Yuan, Aijun Huang, Li Cao, Cheng He

Cell Death Dis. 2018 Feb; 9(2): 181. Published online 2018 Feb 7. doi: 10.1038/s41419-017-0236-8

PMCID:: PMC5833847

Abstract Article PDF–3.0M

Select item 58337963.

Hemopexin is required for adult neurogenesis in the subventricular zone/olfactory bulb pathway

Yanling Zhu, Yang Qiu, Mengjia Chen, Yi Zhang, Li Cao, Zhida Su, Yimin Yuan, Aijun Huang, Yinyan Pu, Cheng He

Cell Death Dis. 2018 Mar; 9(3): 268. Published online 2018 Feb 15. doi: 10.1038/s41419-018-0328-0

PMCID:: PMC5833796

Abstract Article PDF–6.8M

Select item 46873884.

Dysregulation of the haem-haemopexin axis is associated with severe malaria in a case–control study of Ugandan children

Robyn E. Elphinstone, Frank Riley, Tian Lin, Sarah Higgins, Aggrey Dhabangi, Charles Musoke, Christine Cserti-Gazdewich, Raymond F. Regan, H. Shaw Warren, Kevin C. Kain

Malar J. 2015; 14: 511. Published online 2015 Dec 21. doi: 10.1186/s12936-015-1028-1

PMCID:: PMC4687388

Abstract Article PDF–1.0M

Select item 36948945.

Lack of Plasma Protein Hemopexin Results in Increased Duodenal Iron Uptake

Veronica Fiorito, Simonetta Geninatti Crich, Lorenzo Silengo, Silvio Aime, Fiorella Altruda, Emanuela Tolosano

PLoS One. 2013; 8(6): e68146. Published online 2013 Jun 27. doi: 10.1371/journal.pone.0068146

PMCID:: PMC3694894

Abstract Article PDF–2.1M

Select item 33455646.

Hemopexin Decreases Hemin Accumulation and Catabolism by Neural Cells

Jing Chen-Roetling, Wenpei Liu, Raymond F. Regan

Neurochem Int. Author manuscript; available in PMC 2013 Apr 1.

Published in final edited form as: Neurochem Int. 2012 Apr; 60(5): 488–494. Published online 2012 Feb 7. doi: 10.1016/j.neuint.2012.01.024

PMCID:: PMC3345564

Abstract Article PDF–1.8M

Select item 31021077.

A Role for Hemopexin in Oligodendrocyte Differentiation and Myelin Formation

Noemi Morello, Federico Tommaso Bianchi, Paola Marmiroli, Elisabetta Tonoli, Virginia Rodriguez Menendez, Lorenzo Silengo, Guido Cavaletti, Alessandro Vercelli, Fiorella Altruda, Emanuela Tolosano

PLoS One. 2011; 6(5): e20173. Published online 2011 May 25. doi: 10.1371/journal.pone.0020173

PMCID:: PMC3102107

Abstract Article PDF–646K

Select item 30612528.

Increased Striatal Injury and Behavioral Deficits after Intracerebral Hemorrhage in Hemopexin Knockout Mice

Lifen Chen, Xuefeng Zhang, Jing Chen-Roetling, Raymond F. Regan

J Neurosurg. Author manuscript; available in PMC 2012 Apr 1.

Published in final edited form as: J Neurosurg. 2011 Apr; 114(4): 1159–1167. Published online 2010 Dec 3. doi: 10.3171/2010.10.JNS10861

PMCID:: PMC3061252

Abstract Article PDF–1.0M

Select item 27267689.

Hemopexin down-regulates LPS-induced proinflammatory cytokines from macrophages

Xueya Liang, Tian Lin, Guangjie Sun, Laura Beasley-Topliffe, Jean-Marc Cavaillon, H. Shaw Warren

J Leukoc Biol. 2009 Aug; 86(2): 229–235. Published online 2009 Apr 24. doi: 10.1189/jlb.1208742

PMCID:: PMC2726768

Abstract Article

Select item 1071948010.

Free heme and hemopexin in acute kidney injury after cardiopulmonary bypass and transient renal ischemia

Robert Greite, Sebastian Schott, Li Wang, Lukas Gohlke, Kirill Kreimann, Katja Derlin, Marcel Gutberlet, Martina Schmidbauer, Andreas Leffler, Igor Tudorache, Jawad Salman, Fabio Ius, Ruslan Natanov, Christine Fegbeutel, Axel Haverich, Ralf Lichtinghagen, Anne M. Hüsing, Sibylle von Vietinghoff, Roland Schmitt, Nelli Shushakova, Song Rong, Hermann Haller, Kai M. Schmidt‐Ott, Magnus Gram, Vijith Vijayan, Irina Scheffner, Wilfried Gwinner, Stephan Immenschuh

Clin Transl Sci. 2023 Dec; 16(12): 2729–2743. Published online 2023 Oct 30. doi: 10.1111/cts.13667

PMCID:: PMC10719480

Abstract Article PDF–40M

Select item 819642211.

Skeletal muscle heme oxygenase-1 activity regulates aerobic capacity

Rodrigo W. Alves de Souza, David Gallo, Ghee Rye Lee, Eri Katsuyama, Alexa Schaufler, Janick Weber, Eva Csizmadia, George C. Tsokos, Lauren G. Koch, Steven L. Britton, Ulrik Wisløff, Patricia C. Brum, Leo E. Otterbein

Cell Rep. Author manuscript; available in PMC 2021 Jun 12.

Published in final edited form as: Cell Rep. 2021 Apr 20; 35(3): 109018. doi: 10.1016/j.celrep.2021.109018

PMCID:: PMC8196422

Abstract Article PDF–2.8M

Select item 755140412.

Scavenging of Labile Heme by Hemopexin Is a Key Checkpoint in Cancer Growth and Metastases

Giacomo Canesin, Annalisa Di Ruscio, Mailin Li, Simone Ummarino, Andreas Hedblom, Reeham Choudhury, Agnieszka Krzyzanowska, Eva Csizmadia, Macarena Palominos, Anna Stiehm, Alexander Ebralidze, Shao-Yong Chen, Mahmoud A. Bassal, Ping Zhao, Emanuela Tolosano, Laurence Hurley, Anders Bjartell, Daniel G. Tenen, Barbara Wegiel

Cell Rep. Author manuscript; available in PMC 2020 Oct 13.

Published in final edited form as: Cell Rep. 2020 Sep 22; 32(12): 108181. doi: 10.1016/j.celrep.2020.108181

PMCID:: PMC7551404

Abstract Article PDF–2.5M

Select item 721873513.

Hemopexin deficiency promotes acute kidney injury in sickle cell disease

Solomon F. Ofori-Acquah, Rimi Hazra, Oluwaseun O. Orikogbo, Danielle Crosby, Bethany Flage, Ezekiel B. Ackah, Diane Lenhart, Roderick J. Tan, Dario A. Vitturi, Vivian Paintsil, Ellis Owusu-Dabo, Samit Ghosh, in collaboration with the SickleGenAfrica Network

Blood. 2020 Mar 26; 135(13): 1044–1048. Prepublished online 2020 Feb 10. doi: 10.1182/blood.2019002653

PMCID:: PMC7218735

Abstract Article

Select item 488225714.

ApoE^−/− Mice Lacking Hemopexin Develop Increased Atherosclerosis via Mechanisms That Include Oxidative Stress and Altered Macrophage Function

Niyati U. Mehta, Victor Grijalva, Susan Hama, Alan Wagner, Mohamad Navab, Alan M. Fogelman, Srinivasa T. Reddy

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2017 Jun 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2016 Jun; 36(6): 1152–1163. Published online 2016 Apr 14. doi: 10.1161/ATVBAHA.115.306991

PMCID:: PMC4882257

Abstract Article PDF–1.3M

Select item 473663815.

Deletion of the hemopexin or heme oxygenase-2 gene aggravates brain injury following stroma-free hemoglobin-induced intracerebral hemorrhage

Bo Ma, Jason Patrick Day, Harrison Phillips, Bryan Slootsky, Emanuela Tolosano, Sylvain Doré

J Neuroinflammation. 2016; 13: 26. Published online 2016 Feb 1. doi: 10.1186/s12974-016-0490-1

PMCID:: PMC4736638

Abstract Article PDF–2.1M

Select item 442482416.

Hemopexin in severe inflammation and infection: mouse models and human diseases

Tian Lin, Dayana Maita, Sujatha R Thundivalappil, Frank E Riley, Jasmin Hambsch, Linda J Van Marter, Helen A Christou, Lorenzo Berra, Shawn Fagan, David C Christiani, H Shaw Warren

Crit Care. 2015; 19(1): 166. Published online 2015 Apr 15. doi: 10.1186/s13054-015-0885-x

PMCID:: PMC4424824

Abstract Article PDF–758K

Select item 351762817.

Renal cortical hemopexin accumulation in response to acute kidney injury

Richard A. Zager, Ali C. M. Johnson, Kirsten Becker

Am J Physiol Renal Physiol. 2012 Nov 15; 303(10): F1460–F1472. Published online 2012 Sep 19. doi: 10.1152/ajprenal.00426.2012

PMCID:: PMC3517628

Abstract Article

Select item 1027756418.

Free heme exacerbates colonic injury induced by anti-cancer therapy

Philippa Seika, Monika Janikova, Sahana Asokan, Lubica Janovicova, Eva Csizmadia, Mckenzie O’Connell, Simon C. Robson, Jonathan Glickman, Barbara Wegiel

Front Immunol. 2023; 14: 1184105. Published online 2023 Jun 5. doi: 10.3389/fimmu.2023.1184105

PMCID:: PMC10277564

Abstract Article PDF–28M

Select item 534594119.

IL-22 Controls Iron-Dependent Nutritional Immunity Against Systemic Bacterial Infections

Kei Sakamoto, Yun-Gi Kim, Hideki Hara, Nobuhiko Kamada, Gustavo Caballero-Flores, Emanuela Tolosano, Miguel P. Soares, José L. Puente, Naohiro Inohara, Gabriel Núñez

Sci Immunol. Author manuscript; available in PMC 2017 Mar 10.

Published in final edited form as: Sci Immunol. 2017 Feb; 2(8): eaai8371. Published online 2017 Feb 3. doi: 10.1126/sciimmunol.aai8371

PMCID:: PMC5345941

Abstract Article PDF–1.2M

Select item 449612620.

Haemopexin affects iron distribution and ferritin expression in mouse brain

Noemi Morello, Elisabetta Tonoli, Federica Logrand, Veronica Fiorito, Sharmila Fagoonee, Emilia Turco, Lorenzo Silengo, Alessandro Vercelli, Fiorella Altruda, Emanuela Tolosano

J Cell Mol Med. 2009 Oct; 13(10): 4192–4204. Published online 2008 Dec 16. doi: 10.1111/j.1582-4934.2008.00611.x

PMCID:: PMC4496126

Abstract Article PDF–1.5M

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