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Select item 109376331.

KSRP improves pancreatic beta cell function and survival

Leticia Barssotti, Gabriela Moreira Soares, Emílio Marconato-Júnior, Bruna Lourençoni Alves, Kênia Moreno Oliveira, Everardo Magalhães Carneiro, Antonio Carlos Boschero, Helena Cristina Lima Barbosa

Sci Rep. 2024; 14: 6136. Published online 2024 Mar 13. doi: 10.1038/s41598-024-55505-8

PMCID:: PMC10937633

Abstract Article PDF–5.0M

Select item 92629702.

KHSRP loss increases neuronal growth and synaptic transmission and alters memory consolidation through RNA stabilization

Sarah L. Olguin, Priyanka Patel, Courtney N. Buchanan, Michela Dell’Orco, Amy S. Gardiner, Robert Cole, Lauren S. Vaughn, Anitha Sundararajan, Joann Mudge, Andrea M. Allan, Pavel Ortinski, Jonathan L. Brigman, Jeffery L. Twiss, Nora I. Perrone-Bizzozero

Commun Biol. 2022; 5: 672. Published online 2022 Jul 7. doi: 10.1038/s42003-022-03594-4

PMCID:: PMC9262970

Abstract Article PDF–2.6M

Select item 42277543.

Resveratrol post-transcriptionally regulates pro-inflammatory gene expression via regulation of KSRP RNA binding activity

Franziska Bollmann, Julia Art, Jenny Henke, Katharina Schrick, Verena Besche, Matthias Bros, Huige Li, Daniel Siuda, Norbert Handler, Florian Bauer, Thomas Erker, Felix Behnke, Bettina Mönch, Lorena Härdle, Markus Hoffmann, Ching-Yi Chen, Ulrich Förstermann, Verena M. Dirsch, Oliver Werz, Hartmut Kleinert, Andrea Pautz

Nucleic Acids Res. 2014 Nov 10; 42(20): 12555–12569. Published online 2014 Oct 28. doi: 10.1093/nar/gku1033

PMCID:: PMC4227754

Abstract Article PDF–503K

Select item 36296904.

KSRP: A Checkpoint for Inflammatory Cytokine Production in Astrocytes

XUELIN LI, WEI-JYE LIN, CHING-YI CHEN, YING SI, XIAOWEN ZHANG, LIANG LU, ESTHER SUSWAM, LEI ZHENG, PETER H. KING

Glia. Author manuscript; available in PMC 2013 Apr 18.

Published in final edited form as: Glia. 2012 Nov; 60(11): 1773–1784. Published online 2012 Jul 28. doi: 10.1002/glia.22396

PMCID:: PMC3629690

Abstract Article PDF–2.5M

Select item 86240315.

Knockout of the KH-Type Splicing Regulatory Protein Drives Glomerulonephritis in MRL-Fas^lpr Mice

Lisa Schmidtke, Myriam Meineck, Sabrina Saurin, Svenja Otten, Fabian Gather, Katharina Schrick, Rudolf Käfer, Wilfried Roth, Hartmut Kleinert, Julia Weinmann-Menke, Andrea Pautz

Cells. 2021 Nov; 10(11): 3167. Published online 2021 Nov 14. doi: 10.3390/cells10113167

PMCID:: PMC8624031

Abstract Article PDF–3.3M

Select item 75307196.

FUBP1 and FUBP2 enforce distinct epigenetic setpoints for MYC expression in primary single murine cells

Ying Zheng, Wendy Dubois, Craig Benham, Eric Batchelor, David Levens

Commun Biol. 2020; 3: 545. Published online 2020 Oct 1. doi: 10.1038/s42003-020-01264-x

PMCID:: PMC7530719

Abstract Article PDF–1.9M

Select item 43066787.

KSRP is critical in governing hepatic lipid metabolism through controlling Per2 expression

Chu-Fang Chou, Xiaolin Zhu, Yi-Yu Lin, Karen L. Gamble, W. Timothy Garvey, Ching-Yi Chen

J Lipid Res. 2015 Feb; 56(2): 227–240. doi: 10.1194/jlr.M050724

PMCID:: PMC4306678

Abstract Article PDF–2.1M

Select item 41413728.

KSRP Ablation Enhances Brown Fat Gene Program in White Adipose Tissue Through Reduced miR-150 Expression

Chu-Fang Chou, Yi-Yu Lin, Hsu-Kun Wang, Xiaolin Zhu, Matteo Giovarelli, Paola Briata, Roberto Gherzi, W. Timothy Garvey, Ching-Yi Chen

Diabetes. 2014 Sep; 63(9): 2949–2961. Published online 2014 Aug 16. doi: 10.2337/db13-1901

PMCID:: PMC4141372

Abstract Article PDF–1.8M

Select item 40542959.

KSRP and MicroRNA 145 Are Negative Regulators of Lipolysis in White Adipose Tissue

Yi-Yu Lin, Chu-Fang Chou, Matteo Giovarelli, Paola Briata, Roberto Gherzi, Ching-Yi Chen

Mol Cell Biol. 2014 Jun; 34(12): 2339–2349. doi: 10.1128/MCB.00042-14

PMCID:: PMC4054295

Abstract Article PDF–2.7M

Select item 327873110.

PI3K/AKT signaling determines a dynamic switch between distinct KSRP functions favoring skeletal myogenesis

P Briata, W-J Lin, M Giovarelli, M Pasero, C-F Chou, M Trabucchi, M G Rosenfeld, C-Y Chen, R Gherzi

Cell Death Differ. 2012 Mar; 19(3): 478–487. Published online 2011 Sep 2. doi: 10.1038/cdd.2011.117

PMCID:: PMC3278731

Abstract Article PDF–862K

Select item 260278211.

A cytoplasmic variant of the KH-type splicing regulatory protein serves as a decay-promoting factor for phosphoglycerate kinase 2 mRNA in murine male germ cells

Mingang Xu, John R. McCarrey, Norman B. Hecht

Nucleic Acids Res. 2008 Dec; 36(22): 7157–7167. Published online 2008 Nov 10. doi: 10.1093/nar/gkn800

PMCID:: PMC2602782

Abstract Article PDF–7.9M

Select item 757886012.

E3 Ligase FBXW2 Is a New Therapeutic Target in Obesity and Atherosclerosis

Cheng Wang, Wenjing Xu, Yuelin Chao, Minglu Liang, Fengxiao Zhang, Kai Huang

Adv Sci (Weinh) 2020 Oct; 7(20): 2001800. Published online 2020 Aug 26. doi: 10.1002/advs.202001800

PMCID:: PMC7578860

Abstract Article PDF–5.3M

Select item 425009713.

H19 long noncoding RNA controls the mRNA decay promoting function of KSRP

Matteo Giovarelli, Gabriele Bucci, Andres Ramos, Domenico Bordo, Carol J. Wilusz, Ching-Yi Chen, Margherita Puppo, Paola Briata, Roberto Gherzi

Proc Natl Acad Sci U S A. 2014 Nov 25; 111(47): E5023–E5028. Published online 2014 Nov 10. doi: 10.1073/pnas.1415098111

PMCID:: PMC4250097

Abstract Article PDF–1.1M

Select item 335508814.

miR-27b Targets KSRP to Coordinate TLR4-Mediated Epithelial Defense against Cryptosporidium parvum Infection

Rui Zhou, Ai-Yu Gong, Alex N. Eischeid, Xian-Ming Chen

PLoS Pathog. 2012 May; 8(5): e1002702. Published online 2012 May 17. doi: 10.1371/journal.ppat.1002702

PMCID:: PMC3355088

Abstract Article PDF–2.6M

Select item 314780115.

Posttranscriptional Control of Type I Interferon Genes by KSRP in the Innate Immune Response against Viral Infection

Wei-Jye Lin, Xiaojia Zheng, Chen-Chung Lin, Jun Tsao, Xiaolin Zhu, James J. Cody, Jennifer M. Coleman, Roberto Gherzi, Ming Luo, Tim M. Townes, Jacqueline N. Parker, Ching-Yi Chen

Mol Cell Biol. 2011 Aug; 31(16): 3196–3207. doi: 10.1128/MCB.05073-11

PMCID:: PMC3147801

Abstract Article PDF–2.5M

Select item 276833216.

The RNA-binding Protein KSRP Promotes the Biogenesis of a Subset of miRNAs

Michele Trabucchi, Paola Briata, MariaFlor Garcia-Mayoral, Astrid D. Haase, Witold Filipowicz, Andres Ramos, Roberto Gherzi, Michael G. Rosenfeld

Nature. Author manuscript; available in PMC 2009 Dec 18.

Published in final edited form as: Nature. 2009 Jun 18; 459(7249): 1010–1014. Published online 2009 May 20. doi: 10.1038/nature08025

PMCID:: PMC2768332

Abstract Article PDF–753K

Select item 32939217.

Differentiation-induced Colocalization of the KH-type Splicing Regulatory Protein with Polypyrimidine Tract Binding Protein and the c-src Pre-mRNA

Megan P. Hall, Sui Huang, Douglas L. Black

Mol Biol Cell. 2004 Feb; 15(2): 774–786. doi: 10.1091/mbc.E03-09-0692

PMCID:: PMC329392

Abstract Article PDF–1.0M

Select item 382834818.

KSRP Modulation of GAP-43 mRNA Stability Restricts Axonal Outgrowth in Embryonic Hippocampal Neurons

Clark W. Bird, Amy S. Gardiner, Federico Bolognani, Daniel C. Tanner, Ching-Yi Chen, Wei-Jye Lin, Soonmoon Yoo, Jeffery L. Twiss, Nora Perrone- Bizzozero

PLoS One. 2013; 8(11): e79255. Published online 2013 Nov 14. doi: 10.1371/journal.pone.0079255