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Select item 108741021.

Impaired motor unit recovery and maintenance in a knock-in mouse model of ALS-associated Kif5a variant

Kelly A. Rich, Megan G. Pino, Mehmet E. Yalvac, Ashley Fox, Hallie Harris, Maria H. H. Balch, W. David Arnold, Stephen J. Kolb

Neurobiol Dis. Author manuscript; available in PMC 2024 Feb 17.

Published in final edited form as: Neurobiol Dis. 2023 Jun 15; 182: 106148. Published online 2023 May 8. doi: 10.1016/j.nbd.2023.106148

PMCID:: PMC10874102

Article PDF–1.6M

Select item 93226612.

An ALS‐associated KIF5A mutant forms oligomers and aggregates and induces neuronal toxicity

Juri Nakano, Kyoko Chiba, Shinsuke Niwa

Genes Cells. 2022 Jun; 27(6): 421–435. Published online 2022 May 20. doi: 10.1111/gtc.12936

PMCID:: PMC9322661

Article PDF–4.7M

Select item 80787663.

KIF5A-dependent axonal transport deficiency disrupts autophagic flux in trimethyltin chloride-induced neurotoxicity

Mengyu Liu, Huifeng Pi, Yu Xi, Liting Wang, Li Tian, Mengyan Chen, Jia Xie, Ping Deng, Tao Zhang, Chao Zhou, Yidan Liang, Lei Zhang, Mindi He, Yonghui Lu, Chunhai Chen, Zhengping Yu, Zhou Zhou

Autophagy. 2021; 17(4): 903–924. Published online 2020 Mar 30. doi: 10.1080/15548627.2020.1739444

PMCID:: PMC8078766

Article PDF–5.6M

Select item 27857424.

Tight Functional Coupling of Kinesin-1A and Dynein Motors in the Bidirectional Transport of Neurofilaments

Atsuko Uchida, Nael H. Alami, Anthony Brown

Mol Biol Cell. 2009 Dec 1; 20(23): 4997–5006. doi: 10.1091/mbc.E09-04-0304

PMCID:: PMC2785742

Article PDF–1.9M

Select item 21728775.

Abnormal neurofilament transport caused by targeted disruption of neuronal kinesin heavy chain KIF5A

Chun-Hong Xia, Elizabeth A. Roberts, Lu-Shiun Her, Xinran Liu, David S. Williams, Don W. Cleveland, Lawrence S.B. Goldstein

J Cell Biol. 2003 Apr 14; 161(1): 55–66. doi: 10.1083/jcb.200301026

PMCID:: PMC2172877

Article PDF–574K

Select item 103179816.

Activation of TLR7-mediated autophagy increases epileptic susceptibility via reduced KIF5A-dependent GABA_A receptor transport in a murine model

Jing Liu, Pingyang Ke, Haokun Guo, Juan Gu, Yan Liu, Xin Tian, Xuefeng Wang, Fei Xiao

Exp Mol Med. 2023 Jun; 55(6): 1159–1173. Published online 2023 Jun 1. doi: 10.1038/s12276-023-01000-5

PMCID:: PMC10317981

Article PDF–5.9M

Select item 89477667.

Quantitative transportomics identifies Kif5a as a major regulator of neurodegeneration

Sahil H Shah, Lucio M Schiapparelli, Yuanhui Ma, Satoshi Yokota, Melissa Atkins, Xin Xia, Evan G Cameron, Thanh Huang, Sarah Saturday, Catalina B Sun, Cara Knasel, Seth Blackshaw, John R Yates, Hollis T Cline, Jeffrey L Goldberg

eLife. 2022; 11: e68148. Published online 2022 Mar 8. doi: 10.7554/eLife.68148

PMCID:: PMC8947766

Article PDF–6.3M

Select item 68735888.

Postsynaptic density protein 95 (PSD-95) is transported by KIF5 to dendritic regions

Ki-Seo Yoo, Kina Lee, Jun-Young Oh, Hyoeun Lee, Hyungju Park, Young Seok Park, Hyong Kyu Kim

Mol Brain. 2019; 12: 97. Published online 2019 Nov 21. doi: 10.1186/s13041-019-0520-x

PMCID:: PMC6873588

Article PDF–3.6M

Select item 54968699.

KIF5A transports collagen vesicles of myofibroblasts during pleural fibrosis

Hirotoshi Kamata, Yoshikazu Tsukasaki, Tsuyoshi Sakai, Reiko Ikebe, Julia Wang, Ann Jeffers, Jake Boren, Shuzi Owens, Takahiro Suzuki, Masaaki Higashihara, Steven Idell, Torry A. Tucker, Mitsuo Ikebe

Sci Rep. 2017; 7: 4556. Published online 2017 Jul 4. doi: 10.1038/s41598-017-04437-7

PMCID:: PMC5496869

Article PDF–2.3M

Select item 423455010.

New approach to capture and characterize synaptic proteome

Xin-An Liu, Beena Kadakkuzha, Bruce Pascal, Caitlin Steckler, Komolitdin Akhmedov, Long Yan, Michael Chalmers, Sathyanarayanan V. Puthanveettil

Proc Natl Acad Sci U S A. 2014 Nov 11; 111(45): 16154–16159. Published online 2014 Oct 28. doi: 10.1073/pnas.1401483111

PMCID:: PMC4234550

Article PDF–1.4M

Select item 371898511.

Kinesin-1–syntaphilin coupling mediates activity-dependent regulation of axonal mitochondrial transport

Yanmin Chen, Zu-Hang Sheng

J Cell Biol. 2013 Jul 22; 202(2): 351–364. doi: 10.1083/jcb.201302040

PMCID:: PMC3718985

Article PDF–3.6M

Select item 333238612.

Axonal transport deficit in a KIF5A^–/– mouse model

Kathrin N. Karle, Diana Möckel, Evan Reid, Ludger Schöls

Neurogenetics. 2012; 13(2): 169–179. Published online 2012 Apr 1. doi: 10.1007/s10048-012-0324-y

PMCID:: PMC3332386

Article PDF–437K

Select item 228950713.

Cloning and expression of a human kinesin heavy chain gene: interaction of the COOH-terminal domain with cytoplasmic microtubules in transfected CV-1 cells

J Cell Biol. 1992 Jun 2; 117(6): 1263–1275. doi: 10.1083/jcb.117.6.1263

PMCID:: PMC2289507

Summary PDF–4.0M

Select item 212033914.

Identification and partial characterization of mitotic centromere- associated kinesin, a kinesin-related protein that associates with centromeres during mitosis

J Cell Biol. 1995 Jan 1; 128(1): 95–104. doi: 10.1083/jcb.128.1.95

PMCID:: PMC2120339

Summary PDF–2.4M

Select item 702836815.

Specific depletion of the motor protein KIF5B leads to deficits in dendritic transport, synaptic plasticity and memory

Junjun Zhao, Albert Hiu Ka Fok, Ruolin Fan, Pui-Yi Kwan, Hei-Lok Chan, Louisa Hoi-Ying Lo, Ying-Shing Chan, Wing-Ho Yung, Jiandong Huang, Cora Sau Wan Lai, Kwok-On Lai

eLife. 2020; 9: e53456. Published online 2020 Jan 21. doi: 10.7554/eLife.53456

PMCID:: PMC7028368

Article PDF–5.0M

Select item 615841916.

Kinesin-1 Proteins KIF5A, -5B, and -5C Promote Anterograde Transport of Herpes Simplex Virus Enveloped Virions in Axons

Grayson DuRaine, Todd W. Wisner, Paul Howard, David C. Johnson

J Virol. 2018 Oct 15; 92(20): e01269-18. Prepublished online 2018 Aug 1. Published online 2018 Sep 26. doi: 10.1128/JVI.01269-18

PMCID:: PMC6158419

Article PDF–1.5M

Select item 559832117.

Spatiotemporally Controlled Ablation of Klf5 Results in Dysregulated Epithelial Homeostasis in Adult Mouse Corneas

Chelsea L. Loughner, Anil Tiwari, Doreswamy Kenchegowda, Sudha Swamynathan, Shivalingappa K. Swamynathan

Invest Ophthalmol Vis Sci. 2017 Sep; 58(11): 4683–4693. doi: 10.1167/iovs.17-22498

PMCID:: PMC5598321

Article PDF–3.0M

Select item 314441418.

Preferential binding of a kinesin-1 motor to GTP-tubulin–rich microtubules underlies polarized vesicle transport

Takao Nakata, Shinsuke Niwa, Yasushi Okada, Franck Perez, Nobutaka Hirokawa

J Cell Biol. 2011 Jul 25; 194(2): 245–255. doi: 10.1083/jcb.201104034

PMCID:: PMC3144414

Article PDF–3.3M

Select item 38509519.

A Kinesin Heavy Chain (KIF5A) Mutation in Hereditary Spastic Paraplegia (SPG10)

Evan Reid, Mark Kloos, Allison Ashley-Koch, Lori Hughes, Simon Bevan, Ingrid K. Svenson, Felicia Lennon Graham, Perry C. Gaskell, Andrew Dearlove, Margaret A. Pericak-Vance, David C. Rubinsztein, Douglas A. Marchuk

Am J Hum Genet. 2002 Nov; 71(5): 1189–1194. Published online 2002 Sep 24. doi: 10.1086/344210