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Select item 99484091.

The critical role of KLF4 in regulating the activation of A1/A2 reactive astrocytes following ischemic stroke

Cong Wang, Longxuan Li

J Neuroinflammation. 2023; 20: 44. Published online 2023 Feb 23. doi: 10.1186/s12974-023-02742-9

PMCID:: PMC9948409

Abstract Article PDF–7.0M

Select item 97570502.

KLF4 inhibits early neural differentiation of ESCs by coordinating specific 3D chromatin structure

Jinfang Bi, Wenbin Wang, Meng Zhang, Baoying Zhang, Man Liu, Guangsong Su, Fuquan Chen, Bohan Chen, Tengfei Shi, Yaoqiang Zheng, Xueyuan Zhao, Zhongfang Zhao, Jiandang Shi, Peng Li, Lei Zhang, Wange Lu

Nucleic Acids Res. 2022 Nov 28; 50(21): 12235–12250. Published online 2022 Dec 7. doi: 10.1093/nar/gkac1118

PMCID:: PMC9757050

Abstract Article PDF–2.9M

Select item 94066103.

Krüppel-like Factor 4 Supports the Expansion of Leukemia Stem Cells in MLL-AF9-driven Acute Myeloid Leukemia

Andrew Henry Lewis, Cory Seth Bridges, David Neal Moorshead, Taylor J Chen, Wa Du, Barry Zorman, Pavel Sumazin, Monica Puppi, H Daniel Lacorazza

Stem Cells. 2022 Aug; 40(8): 736–750. Published online 2022 May 10. doi: 10.1093/stmcls/sxac033

PMCID:: PMC9406610

Abstract Article PDF–22M

Select item 91336454.

Argonaute proteins regulate a specific network of genes through KLF4 in mouse embryonic stem cells

Madlen Müller, Moritz Schaefer, Tara Fäh, Daniel Spies, Victoria Hermes, Richard Patryk Ngondo, Rodrigo Peña-Hernández, Raffaella Santoro, Constance Ciaudo

Stem Cell Reports. 2022 May 10; 17(5): 1070–1080. Published online 2022 Apr 21. doi: 10.1016/j.stemcr.2022.03.014

PMCID:: PMC9133645

Abstract Article PDF–3.3M

Select item 90674085.

In vivo temporal resolution of acute promyelocytic leukemia progression reveals a role of Klf4 in suppressing early leukemic transformation

Glòria Mas, Fabio Santoro, Enrique Blanco, Gianni Paolo Gamarra Figueroa, François Le Dily, Gianmaria Frigè, Enrique Vidal, Francesca Mugianesi, Cecilia Ballaré, Arantxa Gutierrez, Aleksandra Sparavier, Marc A. Marti-Renom, Saverio Minucci, Luciano Di Croce

Genes Dev. 2022 Apr 1; 36(7-8): 451–467. doi: 10.1101/gad.349115.121

PMCID:: PMC9067408

Abstract Article PDF–10M

Select item 88954346.

Klf4 Promotes Dentinogenesis and Odontoblastic Differentiation via Modulation of TGF-β Signaling Pathway and Interaction With Histone Acetylation

Huangheng Tao, Heng Lin, Zheyi Sun, Fei Pei, Jie Zhang, Shuo Chen, Huan Liu, Zhi Chen

J Bone Miner Res. Author manuscript; available in PMC 2022 Mar 4.

Published in final edited form as: J Bone Miner Res. 2019 Aug; 34(8): 1502–1516. Published online 2019 May 21. doi: 10.1002/jbmr.3716

PMCID:: PMC8895434

Abstract Article PDF–2.8M

Select item 80677187.

KLF4 Regulates Metabolic Homeostasis in Response to Stress

Andrew Blum, Kate Mostow, Kailey Jackett, Estelle Kelty, Tenzing Dakpa, Carly Ryan, Engda Hagos

Cells. 2021 Apr; 10(4): 830. Published online 2021 Apr 7. doi: 10.3390/cells10040830

PMCID:: PMC8067718

Abstract Article PDF–19M

Select item 73567898.

Epigallocatechin-3-Gallate (EGCG), an Active Compound of Green Tea Attenuates Acute Lung Injury Regulating Macrophage Polarization and Krüpple-Like-Factor 4 (KLF4) Expression

Saleh A. Almatroodi, Ahmad Almatroudi, Mohammed A. Alsahli, Mohammad A. Aljasir, Mansoor Ali Syed, Arshad Husain Rahmani

Molecules. 2020 Jun; 25(12): 2853. Published online 2020 Jun 20. doi: 10.3390/molecules25122853

PMCID:: PMC7356789

Abstract Article PDF–3.0M

Select item 73397469.

KLF4 is involved in the organization and regulation of pluripotency-associated 3D enhancer networks

Dafne Campigli Di Giammartino, Andreas Kloetgen, Alexander Polyzos, Yiyuan Liu, Daleum Kim, Dylan Murphy, Abderhman Abuhashem, Paola Cavaliere, Boaz Aronson, Veevek Shah, Noah Dephoure, Matthias Stadtfeld, Aristotelis Tsirigos, Effie Apostolou

Nat Cell Biol. Author manuscript; available in PMC 2020 Jul 7.

Published in final edited form as: Nat Cell Biol. 2019 Oct; 21(10): 1179–1190. Published online 2019 Sep 23. doi: 10.1038/s41556-019-0390-6

PMCID:: PMC7339746

Abstract Article PDF–2.8M

Select item 713955010.

Targeted Krüppel-Like Factor 4 Gene Knock-Out in Retinal Ganglion Cells Improves Visual Function in Multiple Sclerosis Mouse Model

Venu Talla, Rajeshwari Koilkonda

eNeuro. 2020 Mar-Apr; 7(2): ENEURO.0320-19.2020. Prepublished online 2020 Mar 12. Published online 2020 Mar 19. doi: 10.1523/ENEURO.0320-19.2020

PMCID:: PMC7139550

Abstract Article PDF–4.6M

Select item 704374811.

KLF4 is required for suppression of histamine synthesis by polyamines during bone marrow-derived mast cell differentiation

Kazuhiro Nishimura, Moemi Okamoto, Rina Shibue, Toshio Mizuta, Toru Shibayama, Tetsuhiko Yoshino, Teruki Murakami, Masashi Yamaguchi, Satoshi Tanaka, Toshihiko Toida, Kazuei Igarashi

PLoS One. 2020; 15(2): e0229744. Published online 2020 Feb 26. doi: 10.1371/journal.pone.0229744

PMCID:: PMC7043748

Abstract Article PDF–2.2M

Select item 663913012.

KLF4 as a rheostat of osteolysis and osteogenesis in prostate tumors in the bone

Evelyne Tassone, Vivian Bradaschia-Correa, Xiaozhong Xiong, Ana Sastre-Perona, Anne Marie Josephson, Alireza Khodadadi-Jamayran, Jonathan Melamed, Lei Bu, David J Kahler, Liliana Ossowski, Philipp Leucht, Markus Schober, Elaine L Wilson

Oncogene. Author manuscript; available in PMC 2019 Dec 25.

Published in final edited form as: Oncogene. 2019 Jul; 38(29): 5766–5777. Published online 2019 Jun 25. doi: 10.1038/s41388-019-0841-3

PMCID:: PMC6639130

Abstract Article PDF–2.6M

Select item 631804913.

Increased genetic instability and accelerated progression of colitis-associated colorectal cancer through intestinal epithelium-specific deletion of Klf4

Vincent W. Yang, Yang Liu, Julie Kim, Kenneth R. Shroyer, Agnieszka B. Bialkowska

Mol Cancer Res. Author manuscript; available in PMC 2020 Jan 1.

Published in final edited form as: Mol Cancer Res. 2019 Jan; 17(1): 165–176. Published online 2018 Aug 14. doi: 10.1158/1541-7786.MCR-18-0399

PMCID:: PMC6318049

Abstract Article PDF–2.7M

Select item 625799114.

Short-term administration of Nicotinamide Mononucleotide preserves cardiac mitochondrial homeostasis and prevents heart failure

Rongli Zhang, Yuyan Shen, Lin Zhou, Panjamaporn Sangwung, Hisashi Fujioka, Lilei Zhang, Xudong Liao

J Mol Cell Cardiol. Author manuscript; available in PMC 2018 Nov 27.

Published in final edited form as: J Mol Cell Cardiol. 2017 Nov; 112: 64–73. Published online 2017 Sep 5. doi: 10.1016/j.yjmcc.2017.09.001

PMCID:: PMC6257991

Abstract Article PDF–1.6M

Select item 572179315.

Smooth Muscle–Selective Nuclear Factor‐κB Inhibition Reduces Phosphate‐Induced Arterial Medial Calcification in Mice With Chronic Kidney Disease

Tadashi Yoshida, Maho Yamashita, Chihiro Horimai, Matsuhiko Hayashi

J Am Heart Assoc. 2017 Nov; 6(11): e007248. Published online 2017 Nov 16. doi: 10.1161/JAHA.117.007248

PMCID:: PMC5721793

Abstract Article PDF–6.5M

Select item 566667716.

A dynamic interplay of enhancer elements regulates Klf4 expression in naïve pluripotency

Liangqi Xie, Sharon E. Torigoe, Jifang Xiao, Daniel H. Mai, Li Li, Fred P. Davis, Peng Dong, Herve Marie-Nelly, Jonathan Grimm, Luke Lavis, Xavier Darzacq, Claudia Cattoglio, Zhe Liu, Robert Tjian

Genes Dev. 2017 Sep 1; 31(17): 1795–1808. doi: 10.1101/gad.303321.117

PMCID:: PMC5666677

Abstract Article PDF–5.0M

Select item 539183517.

miR-483 Targeting of CTGF Suppresses Endothelial-to-Mesenchymal Transition: Therapeutic Implications in Kawasaki Disease

Ming He, Zhen Chen, Marcy Martin, Jin Zhang, Panjamaporn Sangwung, Brian Woo, Adriana H. Tremoulet, Chisato Shimizu, Mukesh K. Jain, Jane C. Burns, John Y-J. Shyy

Circ Res. Author manuscript; available in PMC 2018 Jan 20.

Published in final edited form as: Circ Res. 2017 Jan 20; 120(2): 354–365. Published online 2016 Dec 6. doi: 10.1161/CIRCRESAHA.116.310233