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Select item 78634071.

Neuron type‐specific increase in lamin B1 contributes to nuclear dysfunction in Huntington’s disease

Rafael Alcalá‐Vida, Marta Garcia‐Forn, Carla Castany‐Pladevall, Jordi Creus‐Muncunill, Yoko Ito, Enrique Blanco, Arantxa Golbano, Kilian Crespí‐Vázquez, Aled Parry, Guy Slater, Shamith Samarajiwa, Sandra Peiró, Luciano Di Croce, Masashi Narita, Esther Pérez‐Navarro

EMBO Mol Med. 2021 Feb 5; 13(2): e12105. Published online 2020 Dec 28. doi: 10.15252/emmm.202012105

PMCID:: PMC7863407

Article PDF–6.7M

Select item 70608052.

Dynamic Lamin B1-Gene Association During Oligodendrocyte Progenitor Differentiation

Camila Yattah, Marylens Hernandez, Dennis Huang, HyeJin Park, Will Liao, Patrizia Casaccia

Neurochem Res. Author manuscript; available in PMC 2020 Mar 8.

Published in final edited form as: Neurochem Res. 2020 Mar; 45(3): 606–619. Published online 2020 Feb 4. doi: 10.1007/s11064-019-02941-y

PMCID:: PMC7060805

Article PDF–1.4M

Select item 36688443.

Lamin B1 mediates cell-autonomous neuropathology in a leukodystrophy mouse model

Mary Y. Heng, Shu-Ting Lin, Laure Verret, Yong Huang, Sherry Kamiya, Quasar S. Padiath, Ying Tong, Jorge J. Palop, Eric J. Huang, Louis J. Ptácχek, Ying-Hui Fu

J Clin Invest. 2013 Jun 3; 123(6): 2719–2729. Published online 2013 May 15. doi: 10.1172/JCI66737

PMCID:: PMC3668844

Article PDF–4.2M

Select item 27588044.

The nuclear periphery of embryonic stem cells is a transcriptionally permissive and repressive compartment

Li Luo, Katherine L. Gassman, Lydia M. Petell, Christian L. Wilson, Joerg Bewersdorf, Lindsay S. Shopland

J Cell Sci. 2009 Oct 15; 122(20): 3729–3737. Published online 2009 Sep 22. doi: 10.1242/jcs.052555

PMCID:: PMC2758804

Article

Select item 26501935.

miR-23 regulation of lamin B1 is crucial for oligodendrocyte development and myelination

Shu-Ting Lin, Ying-Hui Fu

Dis Model Mech. 2009 Mar-Apr; 2(3-4): 178–188. Published online 2009 Feb 2. doi: 10.1242/dmm.001065

PMCID:: PMC2650193

Article

Select item 26150916.

Lamin B1 controls oxidative stress responses via Oct-1

Ashraf N. Malhas, Chiu Fan Lee, David J. Vaux

J Cell Biol. 2009 Jan 12; 184(1): 45–55. doi: 10.1083/jcb.200804155

PMCID:: PMC2615091

Article PDF–1.4M

Select item 20640187.

Defects in lamin B1 expression or processing affect interphase chromosome position and gene expression

Ashraf Malhas, Chiu Fan Lee, Rebecca Sanders, Nigel J. Saunders, David J. Vaux

J Cell Biol. 2007 Feb 26; 176(5): 593–603. doi: 10.1083/jcb.200607054

PMCID:: PMC2064018

Article PDF–2.5M

Select item 89465438.

Colocalization Analysis of Peripheral Myelin Protein-22 and Lamin-B1 in the Schwann Cell Nuclei of Wt and TrJ Mice

María Vittoria Di Tomaso, Lucía Vázquez Alberdi, Daniela Olsson, Saira Cancela, Anabel Fernández, Juan Carlos Rosillo, Ana Laura Reyes Ábalos, Magdalena Álvarez Zabaleta, Miguel Calero, Alejandra Kun

Biomolecules. 2022 Mar; 12(3): 456. Published online 2022 Mar 16. doi: 10.3390/biom12030456

PMCID:: PMC8946543

Article PDF–2.1M

Select item 78837419.

Computational analyses reveal spatial relationships between nuclear pore complexes and specific lamins

Mark Kittisopikul, Takeshi Shimi, Meltem Tatli, Joseph Riley Tran, Yixian Zheng, Ohad Medalia, Khuloud Jaqaman, Stephen A. Adam, Robert D. Goldman

J Cell Biol. 2021 Apr 5; 220(4): e202007082. Published online 2021 Feb 11. doi: 10.1083/jcb.202007082

PMCID:: PMC7883741

Article PDF–12M

Select item 775509810.

Development and optimization of a high content analysis platform to identify suppressors of lamin B1 overexpression as a therapeutic strategy for Autosomal Dominant Leukodystrophy

Bruce Nmezi, Laura L. Vollmer, Tong Ying Shun, Albert Gough, Harshvardhan Rolyan, Fang Liu, Yumeng Jia, Quasar S. Padiath, Andreas Vogt

SLAS Discov. Author manuscript; available in PMC 2021 Sep 1.

Published in final edited form as: SLAS Discov. 2020 Sep; 25(8): 939–949. Published online 2020 Apr 30. doi: 10.1177/2472555220915821

PMCID:: PMC7755098

Article PDF–865K

Select item 633524011.

Epistasis between Pax6^Sey and genetic background reinforces the value of defined hybrid mouse models for therapeutic trials

Jack W. Hickmott, Uvini Gunawardane, Kimberly Jensen, Andrea J. Korecki, Elizabeth M. Simpson

Gene Ther. 2018; 25(8): 524–537. Published online 2018 Sep 26. doi: 10.1038/s41434-018-0043-6

Correction in:: Gene Ther. 2019; 26(3): 133.

PMCID:: PMC6335240

Article PDF–4.1M

Select item 432144012.

Expression of progerin in aging mouse brains reveals structural nuclear abnormalities without detectible significant alterations in gene expression, hippocampal stem cells or behavior

Jean-Ha Baek, Eva Schmidt, Nikenza Viceconte, Charlotte Strandgren, Karin Pernold, Thibaud J. C. Richard, Fred W. Van Leeuwen, Nico P. Dantuma, Peter Damberg, Kjell Hultenby, Brun Ulfhake, Enrico Mugnaini, Björn Rozell, Maria Eriksson

Hum Mol Genet. 2015 Mar 1; 24(5): 1305–1321. Published online 2014 Oct 24. doi: 10.1093/hmg/ddu541

PMCID:: PMC4321440

Article PDF–1.6M

Select item 415234113.

Do lamin B1 and lamin B2 have redundant functions?

John M Lee, Hea-Jin Jung, Loren G Fong, Stephen G Young

Nucleus. 2014 Jul 1; 5(4): 287–292. Published online 2014 Jun 20. doi: 10.4161/nucl.29615

PMCID:: PMC4152341

Article PDF–15M

Select item 398299414.

Concentration-dependent lamin assembly and its roles in the localization of other nuclear proteins

Yuxuan Guo, Youngjo Kim, Takeshi Shimi, Robert D. Goldman, Yixian Zheng

Mol Biol Cell. 2014 Apr 15; 25(8): 1287–1297. doi: 10.1091/mbc.E13-11-0644

PMCID:: PMC3982994

Article PDF–3.6M

Select item 336417215.

Lamin B1 loss is a senescence-associated biomarker

Adam Freund, Remi-Martin Laberge, Marco Demaria, Judith Campisi

Mol Biol Cell. 2012 Jun 1; 23(11): 2066–2075. doi: 10.1091/mbc.E11-10-0884

PMCID:: PMC3364172

Article PDF–1022K

Select item 315955416.

An absence of both lamin B1 and lamin B2 in keratinocytes has no effect on cell proliferation or the development of skin and hair

Shao H. Yang, Sandy Y. Chang, Liya Yin, Yiping Tu, Yan Hu, Yuko Yoshinaga, Pieter J. de Jong, Loren G. Fong, Stephen G. Young

Hum Mol Genet. 2011 Sep 15; 20(18): 3537–3544. Published online 2011 Jun 9. doi: 10.1093/hmg/ddr266

PMCID:: PMC3159554

Article PDF–477K

Select item 306435117.

Protein farnesylation inhibitors cause donut-shaped cell nuclei attributable to a centrosome separation defect

Valerie L. R. M. Verstraeten, Lana A. Peckham, Michelle Olive, Brian C. Capell, Francis S. Collins, Elizabeth G. Nabel, Stephen G. Young, Loren G. Fong, Jan Lammerding

Proc Natl Acad Sci U S A. 2011 Mar 22; 108(12): 4997–5002. Published online 2011 Mar 7. doi: 10.1073/pnas.1019532108

PMCID:: PMC3064351

Article PDF–946K

Select item 47858818.

Lamin B1 is required for mouse development and nuclear integrity

Laurent Vergnes, Miklós Péterfy, Martin O. Bergo, Stephen G. Young, Karen Reue

Proc Natl Acad Sci U S A. 2004 Jul 13; 101(28): 10428–10433. Published online 2004 Jul 1. doi: 10.1073/pnas.0401424101

PMCID:: PMC478588

Article PDF–541K

Select item 784930319.

Lamin B1 decline underlies age‐related loss of adult hippocampal neurogenesis

Tracy A Bedrosian, Judith Houtman, Juan Sebastian Eguiguren, Saeed Ghassemzadeh, Nicole Rund, Nicole M Novaresi, Lauren Hu, Sarah L. Parylak, Ahmet M Denli, Lynne Randolph‐Moore, Takashi Namba, Fred H Gage, Tomohisa Toda

EMBO J. 2021 Feb 1; 40(3): e105819. Published online 2020 Dec 10. doi: 10.15252/embj.2020105819

PMCID:: PMC7849303

Article PDF–7.2M

Select item 654785420.

Lamin B1 loss promotes lung cancer development and metastasis by epigenetic derepression of RET

Yanhan Jia, Joaquim Si-Long Vong, Alina Asafova, Boyan K. Garvalov, Luca Caputo, Julio Cordero, Anshu Singh, Thomas Boettger, Stefan Günther, Ludger Fink, Till Acker, Guillermo Barreto, Werner Seeger, Thomas Braun, Rajkumar Savai, Gergana Dobreva

J Exp Med. 2019 Jun 3; 216(6): 1377–1395. Published online 2019 Apr 23. doi: 10.1084/jem.20181394