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Select item 109700961.

RNA Expression of MMP12 Is Strongly Associated with Inflammatory Bowel Disease and Is Regulated by Metabolic Pathways in RAW 264.7 Macrophages

Laura Arosa, Miguel Camba-Gómez, Luis Francisco Lorenzo-Martín, Laura Clavaín, Miguel López, Javier Conde-Aranda

Int J Mol Sci. 2024 Mar; 25(6): 3167. Published online 2024 Mar 9. doi: 10.3390/ijms25063167

PMCID:: PMC10970096

Article PDF–3.7M

Select item 106856202.

Genetic deletion of MMP12 ameliorates cardiometabolic disease by improving insulin sensitivity, systemic inflammation, and atherosclerotic features in mice

Melina Amor, Valentina Bianco, Martin Buerger, Margarete Lechleitner, Nemanja Vujić, Anja Dobrijević, Alena Akhmetshina, Anita Pirchheim, Birgit Schwarz, Ariane R. Pessentheiner, Franziska Baumgartner, Katharina Rampitsch, Silvia Schauer, Iva Klobučar, Vesna Degoricija, Gudrun Pregartner, Daniel Kummer, Monika Svecla, Gerhard Sommer, Dagmar Kolb, Gerhard A. Holzapfel, Gerald Hoefler, Saša Frank, Giuseppe Danilo Norata, Dagmar Kratky

Cardiovasc Diabetol. 2023; 22: 327. Published online 2023 Nov 28. doi: 10.1186/s12933-023-02064-3

PMCID:: PMC10685620

Article PDF–7.8M

Select item 99073183.

MMP-12 Knockdown Prevents Secondary Brain Damage After Ischemic Stroke in Mice

Vijay Arruri, Anil K Chokkalla, Soomin Jeong, Bharath Chelluboina, Suresh L Mehta, Krishna Kumar Veeravalli, Raghu Vemuganti

Neurochem Int. Author manuscript; available in PMC 2023 Dec 1.

Published in final edited form as: Neurochem Int. 2022 Dec; 161: 105432. Published online 2022 Oct 14. doi: 10.1016/j.neuint.2022.105432

PMCID:: PMC9907318

Article PDF–1.7M

Select item 95859624.

Deletion of matrix metalloproteinase-12 compromises mechanical homeostasis and leads to an aged aortic phenotype in young mice

Bart Spronck, Abhay B. Ramachandra, Lauren Moriyama, Jakub Toczek, Jinah Han, Mehran M. Sadeghi, Jay D. Humphrey

J Biomech. Author manuscript; available in PMC 2023 Aug 1.

Published in final edited form as: J Biomech. 2022 Aug; 141: 111179. Published online 2022 Jun 10. doi: 10.1016/j.jbiomech.2022.111179

PMCID:: PMC9585962

Article PDF–1.5M

Select item 91703835.

Microbiota and adipocyte mitochondrial damage in type 2 diabetes are linked by Mmp12⁺ macrophages

Zhipeng Li, Manoj Gurung, Richard R. Rodrigues, Jyothi Padiadpu, Nolan K. Newman, Nathan P. Manes, Jacob W. Pederson, Renee L. Greer, Stephany Vasquez-Perez, Hyekyoung You, Kaito A. Hioki, Zoe Moulton, Anna Fel, Dominic De Nardo, Amiran K. Dzutsev, Aleksandra Nita-Lazar, Giorgio Trinchieri, Natalia Shulzhenko, Andrey Morgun

J Exp Med. 2022 Jul 4; 219(7): e20220017. Published online 2022 Jun 3. doi: 10.1084/jem.20220017

PMCID:: PMC9170383

Article PDF–8.2M

Select item 89853566.

Macrophage elastase (MMP12) critically contributes to the development of subretinal fibrosis

Caijiao Yi, Jian Liu, Wen Deng, Chang Luo, Jinyan Qi, Mei Chen, Heping Xu

J Neuroinflammation. 2022; 19: 78. Published online 2022 Apr 5. doi: 10.1186/s12974-022-02433-x

PMCID:: PMC8985356

Article PDF–6.5M

Select item 85371437.

The M2a Macrophage Phenotype Accompanies Pulmonary Granuloma Resolution in Mmp12 Knock-Out Mice Instilled with Multiwall Carbon Nanotubes

David Ogburn, Sophia Bhalla, Nan Leffler, Arjun Mohan, Anagha Malur, Achut G. Malur, Matthew McPeek, Barbara P. Barna, Mary Jane Thomassen

Int J Mol Sci. 2021 Oct; 22(20): 11019. Published online 2021 Oct 13. doi: 10.3390/ijms222011019

PMCID:: PMC8537143

Article PDF–5.4M

Select item 85241458.

RSV infection-elicited high MMP-12–producing macrophages exacerbate allergic airway inflammation with neutrophil infiltration

Airi Makino, Takehiko Shibata, Mashiro Nagayasu, Ikuo Hosoya, Toshiyo Nishimura, Chihiro Nakano, Kisaburo Nagata, Toshihiro Ito, Yoshimasa Takahashi, Shigeki Nakamura

iScience. 2021 Oct 22; 24(10): 103201. Published online 2021 Oct 2. doi: 10.1016/j.isci.2021.103201

PMCID:: PMC8524145

Article PDF–4.3M

Select item 73727609.

LPS aggravates lung inflammation induced by RSV by promoting the ERK-MMP-12 signaling pathway in mice

Shenglin Chen, Jun Xie, Keting Zhao, Luo Ren, Yu Deng, Xiaohong Xie, Shiyi Chen, Hongmei Xu, Xiaoru Long, Enmei Liu

Respir Res. 2020; 21: 193. Published online 2020 Jul 21. doi: 10.1186/s12931-020-01453-6

PMCID:: PMC7372760

Article PDF–1.8M

Select item 674086710.

An Adverse Role for Matrix Metalloproteinase 12 after Spinal Cord Injury in Mice

Jennifer E. A. Wells, Tiffany K. Rice, Robert K. Nuttall, Dylan R. Edwards, Hakima Zekki, Serge Rivest, V. Wee Yong

J Neurosci. 2003 Nov 5; 23(31): 10107–10115. doi: 10.1523/JNEUROSCI.23-31-10107.2003

PMCID:: PMC6740867

Article PDF–467K

Select item 672962411.

The Expression of Matrix Metalloproteinase-12 by Oligodendrocytes Regulates Their Maturation and Morphological Differentiation

Peter H. Larsen, V. Wee Yong

J Neurosci. 2004 Sep 1; 24(35): 7597–7603. doi: 10.1523/JNEUROSCI.2092-04.2004

PMCID:: PMC6729624

Article PDF–369K

Select item 648067312.

Delayed Astrogliosis Associated with Reduced M1 Microglia Activation in Matrix Metalloproteinase 12 Knockout Mice during Theiler’s Murine Encephalomyelitis

Florian Hansmann, Ning Zhang, Vanessa Herder, Eva Leitzen, Wolfgang Baumgärtner

Int J Mol Sci. 2019 Apr; 20(7): 1702. Published online 2019 Apr 5. doi: 10.3390/ijms20071702

PMCID:: PMC6480673

Article PDF–4.9M

Select item 616961413.

Post-stroke mRNA expression profile of MMPs: effect of genetic deletion of MMP-12

Koteswara Rao Nalamolu, Bharath Chelluboina, Ian B Magruder, Diane N Fru, Adithya Mohandass, Ishwarya Venkatesh, Jeffrey D Klopfenstein, David M Pinson, Krishna M Boini, Krishna Kumar Veeravalli

Stroke Vasc Neurol. 2018 Sep; 3(3): 153–159. Published online 2018 Mar 9. doi: 10.1136/svn-2018-000142

PMCID:: PMC6169614

Article PDF–916K

Select item 595581514.

Transcriptional networks of progressive diabetic peripheral neuropathy in the db/db mouse model of type 2 diabetes: an inflammatory story

Lucy M. Hinder, Benjamin J. Murdock, Meeyoung Park, Diane E. Bender, Phillipe D. O’Brien, Amy E. Rumora, Junguk Hur, Eva L. Feldman

Exp Neurol. Author manuscript; available in PMC 2019 Jul 1.

Published in final edited form as: Exp Neurol. 2018 Jul; 305: 33–43. Published online 2018 Mar 14. doi: 10.1016/j.expneurol.2018.03.011

PMCID:: PMC5955815

Article PDF–616K

Select item 591861815.

Distinct Requirements for Extracellular and Intracellular MMP12 in the Development of the Adult V-SVZ Neural Stem Cell Niche

Xiwei Shan, Lyl Tomlinson, Qian Yang, Holly Colognato

Stem Cell Reports. 2018 Mar 13; 10(3): 984–999. Published online 2018 Mar 1. doi: 10.1016/j.stemcr.2018.01.038

PMCID:: PMC5918618

Article PDF–5.5M

Select item 550281416.

Effects of MMP12 on cell motility and inflammation during corneal epithelial repair

Marie Wolf, Inna Maltseva, Selene M. Clay, Peipei Pan, Abhinay Gajjala, Matilda F. Chan

Exp Eye Res. Author manuscript; available in PMC 2018 Jul 1.

Published in final edited form as: Exp Eye Res. 2017 Jul; 160: 11–20. Published online 2017 Apr 22. doi: 10.1016/j.exer.2017.04.007

PMCID:: PMC5502814

Article PDF–863K

Select item 481072517.

Pulmonary C Fibers Modulate MMP-12 Production via PAR2 and Are Involved in the Long-Term Airway Inflammation and Airway Hyperresponsiveness Induced by Respiratory Syncytial Virus Infection

Na Zang, Jianguo Zhuang, Yu Deng, Zhimei Yang, Zhixu Ye, Xiaohong Xie, Luo Ren, Zhou Fu, Zhengxiu Luo, Fadi Xu, Enmei Liu

J Virol. 2016 Mar 1; 90(5): 2536–2543. Prepublished online 2015 Dec 16. Published online 2016 Feb 11. doi: 10.1128/JVI.02534-15

PMCID:: PMC4810725

Article PDF–2.8M

Select item 473175218.

Matrix metalloproteinase 12 modulates high-fat-diet induced glomerular fibrogenesis and inflammation in a mouse model of obesity

Honglin Niu, Ying Li, Haibin Li, Yanqing Chi, Minghui Zhuang, Tao Zhang, Maodong Liu, Lei Nie

Sci Rep. 2016; 6: 20171. Published online 2016 Jan 29. doi: 10.1038/srep20171

PMCID:: PMC4731752

Article PDF–3.1M

Select item 440685219.

Early Matrix Metalloproteinase-12 Inhibition Worsens Post-Myocardial Infarction Cardiac Dysfunction by Delaying Inflammation Resolution

Rugmani Padmanabhan Iyer, Nicolle L. Patterson, Fouad A. Zouein, Yonggang Ma, Vincent Dive, Lisandra E. de Castro Brás, Merry L. Lindsey

Int J Cardiol. Author manuscript; available in PMC 2016 Apr 15.

Published in final edited form as: Int J Cardiol. 2015 Apr 15; 185: 198–208. Published online 2015 Mar 5. doi: 10.1016/j.ijcard.2015.03.054

PMCID:: PMC4406852

Article PDF–1.3M

Select item 429154820.

Macrophage Elastase Suppresses White Adipose Tissue Expansion with Cigarette Smoking

Takao Tsuji, Neil J. Kelly, Saeko Takahashi, Adriana S. Leme, A. McGarry Houghton, Steven D. Shapiro

Am J Respir Cell Mol Biol. 2014 Dec; 51(6): 822–829. doi: 10.1165/rcmb.2014-0083OC

PMCID:: PMC4291548

Article PDF–1.4M

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