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Select item 109525231.

Myeloperoxidase creates a permissive microenvironmental niche for the progression of multiple myeloma

Connor M. D. Williams, Jacqueline E. Noll, Alanah L. Bradey, Jvaughn Duggan, Vicki J. Wilczek, Makutiro G. Masavuli, Branka Grubor‐Bauk, Romana A. Panagopoulos, Duncan R. Hewett, Krzysztof M. Mrozik, Andrew C. W. Zannettino, Kate Vandyke, Vasilios Panagopoulos

Br J Haematol. 2023 Nov; 203(4): 614–624. Published online 2023 Sep 12. doi: 10.1111/bjh.19102

PMCID:: PMC10952523

Article PDF–4.9M

Select item 108743412.

Targeting myeloperoxidase limits myeloid cell immunosuppression enhancing immune checkpoint therapy for pancreatic cancer

Angisha Basnet, Kaitlyn M. Landreth, Remi Nohoesu, Stell P. Santiago, Werner J. Geldenhuys, Brian A. Boone, Tracy W. Liu

Cancer Immunol Immunother. 2024; 73(3): 57. Published online 2024 Feb 17. doi: 10.1007/s00262-024-03647-z

PMCID:: PMC10874341

Article PDF–1.2M

Select item 102127823.

Myeloperoxidase as a biomarker for intestinal-brain axis dysfunction induced by malnutrition and Cryptosporidium infection in weanling mice

Reinaldo B. Oriá, Deiziane V.S. Costa, Pedro Henrique Q.S. de Medeiros, Cássia R. Roque, Ronaldo P. Dias, Cirle A. Warren, David T. Bolick, Richard L. Guerrant

Braz J Infect Dis. 2023 May-Jun; 27(3): 102776. Published online 2023 May 5. doi: 10.1016/j.bjid.2023.102776

PMCID:: PMC10212782

Article PDF–1.5M

Select item 99446474.

Inhibition of myeloperoxidase enhances immune checkpoint therapy for melanoma

Tracy W Liu, Seth T Gammon, Ping Yang, Wencai Ma, Jing Wang, David Piwnica-Worms

J Immunother Cancer. 2023; 11(2): e005837. Published online 2023 Feb 17. doi: 10.1136/jitc-2022-005837

PMCID:: PMC9944647

Article PDF–6.6M

Select item 84130085.

Radiation Activates Myeloperoxidase (MPO) to Generate Active Chlorine Species (ACS) via a Dephosphorylation Mechanism - Inhibitory Effect of LGM2605

Om P. Mishra, Anatoliy V. Popov, Ralph A. Pietrofesa, Wei-Ting Hwang, Mark Andrake, Eiko Nakamaru-Ogiso, Melpo Christofidou-Solomidou

Biochim Biophys Acta Gen Subj. Author manuscript; available in PMC 2021 Sep 2.

Published in final edited form as: Biochim Biophys Acta Gen Subj. 2020 Jul; 1864(7): 129548. Published online 2020 Feb 5. doi: 10.1016/j.bbagen.2020.129548

PMCID:: PMC8413008

Article PDF–1.8M

Select item 67690816.

Myeloperoxidase Deficiency Inhibits Cognitive Decline in the 5XFAD Mouse Model of Alzheimer’s Disease

Rotem Volkman, Tali Ben-Zur, Anat Kahana, Ben Zion Garty, Daniel Offen

Front Neurosci. 2019; 13: 990. Published online 2019 Sep 24. doi: 10.3389/fnins.2019.00990

PMCID:: PMC6769081

Article PDF–3.6M

Select item 67271367.

Reducing myeloperoxidase activity decreases inflammation and increases cellular protection in ischemic stroke

Hyeon J Kim, Ying Wei, Gregory R Wojtkiewicz, Ji Y Lee, Michael A Moskowitz, John W Chen

J Cereb Blood Flow Metab. 2019 Sep; 39(9): 1864–1877. Published online 2018 Apr 20. doi: 10.1177/0271678X18771978

PMCID:: PMC6727136

Article PDF–1.6M

Select item 65755818.

An activatable PET imaging radioprobe is a dynamic reporter of myeloperoxidase activity in vivo

Cuihua Wang, Edmund Keliher, Matthias W. G. Zeller, Gregory R. Wojtkiewicz, Aaron D. Aguirre, Leonard Buckbinder, Hye-Yeong Kim, Jianqing Chen, Kevin Maresca, Maaz S. Ahmed, Negin Jalali Motlagh, Matthias Nahrendorf, John W. Chen

Proc Natl Acad Sci U S A. 2019 Jun 11; 116(24): 11966–11971. Published online 2019 May 23. doi: 10.1073/pnas.1818434116

PMCID:: PMC6575581

Article PDF–1.1M

Select item 59460299.

Myeloperoxidase Negatively Regulates Neutrophil–Endothelial Cell Interactions by Impairing αMβ2 Integrin Function in Sterile Inflammation

Alan Tseng, Kyungho Kim, Jing Li, Jaehyung Cho

Front Med (Lausanne) 2018; 5: 134. Published online 2018 May 4. doi: 10.3389/fmed.2018.00134

PMCID:: PMC5946029

Article PDF–2.1M

Select item 555210010.

Different behavior of myeloperoxidase in two rodent amoebic liver abscess models

Andrea Cruz-Baquero, Luz María Cárdenas Jaramillo, Manuel Gutiérrez-Meza, Rosa Adriana Jarillo-Luna, Rafael Campos-Rodríguez, Víctor Rivera-Aguilar, Angel Miliar-García, Judith Pacheco-Yepez

PLoS One. 2017; 12(8): e0182480. Published online 2017 Aug 10. doi: 10.1371/journal.pone.0182480

PMCID:: PMC5552100

Article PDF–16M

Select item 535335911.

Myeloperoxidase-mediated protein lysine oxidation generates 2-aminoadipic acid and lysine nitrile in vivo

Hongqiao Lin, Bruce S. Levison, Jennifer A. Buffa, Ying Huang, Xiaoming Fu, Zeneng Wang, Valentin Gogonea, Joseph A. DiDonato, Stanley L. Hazen

Free Radic Biol Med. Author manuscript; available in PMC 2018 Mar 1.

Published in final edited form as: Free Radic Biol Med. 2017 Mar; 104: 20–31. Published online 2017 Jan 6. doi: 10.1016/j.freeradbiomed.2017.01.006

PMCID:: PMC5353359

Article PDF–2.0M

Select item 486545812.

Inhibition of Myeloperoxidase at the Peak of Experimental Autoimmune Encephalomyelitis Restores Blood-Brain-Barrier Integrity and Ameliorates Disease Severity

Hao Zhang, Avijit Ray, Nichole M. Miller, Danielle Hartwig, Kirkwood A. Pritchard, Jr., Bonnie N. Dittel

J Neurochem. Author manuscript; available in PMC 2017 May 12.

Published in final edited form as: J Neurochem. 2016 Feb; 136(4): 826–836. Published online 2015 Nov 30. doi: 10.1111/jnc.13426

PMCID:: PMC4865458

Article PDF–1.4M

Select item 372694613.

Neu-164 and Neu-107, two novel antioxidant and anti-myeloperoxidase compounds, inhibit acute cigarette smoke-induced lung inflammation

Thomas H. Thatcher, Hsi-Min Hsiao, Elhanan Pinner, Moshe Laudon, Stephen J. Pollock, Patricia J. Sime, Richard P. Phipps

Am J Physiol Lung Cell Mol Physiol. 2013 Jul 15; 305(2): L165–L174. Published online 2013 May 17. doi: 10.1152/ajplung.00036.2013

PMCID:: PMC3726946

Article

Select item 362048314.

Resveratrol Confers Protection against Rotenone-Induced Neurotoxicity by Modulating Myeloperoxidase Levels in Glial Cells

Chi Young Chang, Dong-Kug Choi, Dae Kee Lee, Young Jun Hong, Eun Jung Park

PLoS One. 2013; 8(4): e60654. Published online 2013 Apr 8. doi: 10.1371/journal.pone.0060654

PMCID:: PMC3620483

Article PDF–1.5M

Select item 346543215.

The immunodominant myeloperoxidase T-cell epitope induces local cell-mediated injury in antimyeloperoxidase glomerulonephritis

Joshua D. Ooi, Janet Chang, Michael J. Hickey, Dorin-Bogdan Borza, Lars Fugger, Stephen R. Holdsworth, A. Richard Kitching

Proc Natl Acad Sci U S A. 2012 Sep 25; 109(39): E2615–E2624. Published online 2012 Sep 5. doi: 10.1073/pnas.1210147109

PMCID:: PMC3465432

Article PDF–1.8M

Select item 331652716.

Impaired Clearance and Enhanced Pulmonary Inflammatory/Fibrotic Response to Carbon Nanotubes in Myeloperoxidase-Deficient Mice

Anna A. Shvedova, Alexandr A. Kapralov, Wei Hong Feng, Elena R. Kisin, Ashley R. Murray, Robert R. Mercer, Claudette M. St. Croix, Megan A. Lang, Simon C. Watkins, Nagarjun V. Konduru, Brett L. Allen, Jennifer Conroy, Gregg P. Kotchey, Bashir M. Mohamed, Aidan D. Meade, Yuri Volkov, Alexander Star, Bengt Fadeel, Valerian E. Kagan

PLoS One. 2012; 7(3): e30923. Published online 2012 Mar 30. doi: 10.1371/journal.pone.0030923

PMCID:: PMC3316527

Article PDF–529K

Select item 288089617.

Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation

Volker Rudolph, René P Andrié, Tanja K Rudolph, Kai Friedrichs, Anna Klinke, Birgit Hirsch-Hoffmann, Alexander P Schwoerer, Denise Lau, XiaoMing Fu, Karin Klingel, Karsten Sydow, Michael Didié, Anika Seniuk, Eike-Christin von Leitner, Katalin Szoecs, Jan W Schrickel, Hendrik Treede, Ulrich Wenzel, Thorsten Lewalter, Georg Nickenig, Wolfram-Hubertus Zimmermann, Thomas Meinertz, Rainer H Böger, Hermann Reichenspurner, Bruce A Freeman, Thomas Eschenhagen, Heimo Ehmke, Stanley L Hazen, Stephan Willems, Stephan Baldus

Nat Med. Author manuscript; available in PMC 2010 Oct 1.

Published in final edited form as: Nat Med. 2010 Apr; 16(4): 470–474. Published online 2010 Mar 21. doi: 10.1038/nm.2124

PMCID:: PMC2880896

Article PDF–692K

Select item 285672018.

Modulation of arachidonic and linoleic acid metabolites in myeloperoxidase deficient mice during acute inflammation

Lukas Kubala, Kara R. Schmelzer, Anna Klinke, Hana Kolarova, Stephan Baldus, Bruce D. Hammock, Jason P. Eiserich

Free Radic Biol Med. Author manuscript; available in PMC 2011 May 15.

Published in final edited form as: Free Radic Biol Med. 2010 May 15; 48(10): 1311–1320. Published online 2010 Feb 13. doi: 10.1016/j.freeradbiomed.2010.02.010

PMCID:: PMC2856720

Article PDF–1.4M

Select item 283147619.

Bioluminescence imaging of myeloperoxidase activity in vivo

Shimon Gross, Seth T Gammon, Britney L Moss, Daniel Rauch, John Harding, Jay W Heinecke, Lee Ratner, David Piwnica-Worms

Nat Med. Author manuscript; available in PMC 2010 Mar 3.

Published in final edited form as: Nat Med. 2009 Apr; 15(4): 455–461. Published online 2009 Mar 22. doi: 10.1038/nm.1886

PMCID:: PMC2831476

Article PDF–1.0M

Select item 146451720.

Null mutation of myeloperoxidase in mice prevents mechanical activation of neutrophil lysis of muscle cell membranes in vitro and in vivo

Hal X Nguyen, Aldons J Lusis, James G Tidball

J Physiol. 2005 Jun 1; 565(Pt 2): 403–413. Published online 2005 Mar 24. doi: 10.1113/jphysiol.2005.085506

PMCID:: PMC1464517

Article PDF–182K

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