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Select item 82485881.

A Novel Mouse Model for SNP in Steroid Receptor Co-Activator-1 Reveals Role in Bone Density and Breast Cancer Metastasis

Rebecca J Watters, Kostas Verdelis, Peter C Lucas, Shiming Jiang, Yuqing Chen, Feiqi Lu, Benjamin M Martin, Lyuda Lukashova, Geoffrey Pecar, Alejandro Morales-Restrepo, Margaret Hankins, Li Zhu, Peter Mittwede, Ryan J Hartmaier, Peter G Alexander, George C Tseng, Kurt R Weiss, Deborah L Galson, Adrian V Lee, Brendan Lee, Steffi Oesterreich

Endocrinology. 2021 Aug; 162(8): bqab094. Published online 2021 May 7. doi: 10.1210/endocr/bqab094

PMCID:: PMC8248588

Abstract Article

Select item 51792662.

SRC-1 Regulates Blood Pressure and Aortic Stiffness in Female Mice

Antentor Othrell Hinton, Jr, Yongjie Yang, Ann P. Quick, Pingwen Xu, Chitra L. Reddy, Xiaofeng Yan, Corey L. Reynolds, Qingchun Tong, Liangru Zhu, Jianming Xu, Xander H. T. Wehrens, Yong Xu, Anilkumar K. Reddy

PLoS One. 2016; 11(12): e0168644. Published online 2016 Dec 22. doi: 10.1371/journal.pone.0168644

PMCID:: PMC5179266

Abstract Article PDF–1.6M

Select item 29996183.

Steroid receptor coactivator 1 deficiency increases MMTV-neu mediated tumor latency and differentiation specific gene expression, decreases metastasis, and inhibits response to PPAR ligands

Ji Seung Han, David L Crowe

BMC Cancer. 2010; 10: 629. Published online 2010 Nov 16. doi: 10.1186/1471-2407-10-629

PMCID:: PMC2999618

Abstract Article PDF–1.6M

Select item 26590094.

The Role of SRC-1 in Murine Prostate Carcinogenesis Is Nonessential due to a Possible Compensation of SRC-3/AIB1 Overexpression

Jean Ching-Yi Tien, Suoling Zhou, Jianming Xu

Int J Biol Sci. 2009; 5(3): 256–264. Published online 2009 Mar 14. doi: 10.7150/ijbs.5.256

PMCID:: PMC2659009

Abstract Article PDF–1.7M

Select item 24352685.

Loss-of-function Deletion of the Steroid Receptor Coactivaor-1 Gene in Mice Reduces Estrogen Effect on the Vascular Injury Response

Yuhui Yuan, Jianming Xu

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2008 Jun 23.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2007 Jul; 27(7): 1521–1527. Published online 2007 Apr 19. doi: 10.1161/ATVBAHA.107.144477

PMCID:: PMC2435268

Abstract Article PDF–1.5M

Select item 11712756.

Mice deficient in the steroid receptor co-activator 1 (SRC-1) are resistant to thyroid hormone.

R E Weiss, J Xu, G Ning, J Pohlenz, B W O'Malley, S Refetoff

EMBO J. 1999 Apr 1; 18(7): 1900–1904. doi: 10.1093/emboj/18.7.1900

PMCID:: PMC1171275

Summary PDF–157K

Select item 155267.

Mouse steroid receptor coactivator-1 is not essential for peroxisome proliferator-activated receptor α-regulated gene expression

Chao Qi, Yijun Zhu, Jie Pan, Anjana V. Yeldandi, M. Sambasiva Rao, Nobuyo Maeda, V. Subbarao, Sujata Pulikuri, Takashi Hashimoto, Janardan K. Reddy

Proc Natl Acad Sci U S A. 1999 Feb 16; 96(4): 1585–1590. doi: 10.1073/pnas.96.4.1585

PMCID:: PMC15526

Abstract Article PDF–521K

Select item 64616698.

Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis

Yongjie Yang, Agatha A. van der Klaauw, Liangru Zhu, Tessa M. Cacciottolo, Yanlin He, Lukas K. J. Stadler, Chunmei Wang, Pingwen Xu, Kenji Saito, Antentor Hinton, Jr., Xiaofeng Yan, Julia M. Keogh, Elana Henning, Matthew C. Banton, Audrey E. Hendricks, Elena G. Bochukova, Vanisha Mistry, Katherine L. Lawler, Lan Liao, Jianming Xu, Stephen O’Rahilly, Qingchun Tong, UK10K Consortium, Inês Barroso, Bert W. O’Malley, I. Sadaf Farooqi, Yong Xu

Nat Commun. 2019; 10: 1718. Published online 2019 Apr 12. doi: 10.1038/s41467-019-08737-6

PMCID:: PMC6461669

Abstract Article PDF–1.3M

Select item 41796269.

Hepatic SRC-1 Activity Orchestrates Transcriptional Circuitries of Amino Acid Pathways with Potential Relevance for Human Metabolic Pathogenesis

Mounia Tannour-Louet, Brian York, Ke Tang, Erin Stashi, Hichem Bouguerra, Suoling Zhou, Hui Yu, Lee-Jun C. Wong, Robert D. Stevens, Jianming Xu, Christopher B. Newgard, Bert W. O'Malley, Jean-Francois Louet

Mol Endocrinol. 2014 Oct; 28(10): 1707–1718. Published online 2014 Aug 22. doi: 10.1210/me.2014-1083

PMCID:: PMC4179626

Abstract Article

Select item 354102710.

A new isoform of steroid receptor coactivator-1 is crucial for pathogenic progression of endometriosis

Sang Jun Han, Shannon M. Hawkins, Khurshida Begum, Sung Yun Jung, Ertug Kovanci, Jun Qin, John P. Lydon, Francesco J. DeMayo, Bert W. O'Malley

Nat Med. Author manuscript; available in PMC 2013 Jan 9.

Published in final edited form as: Nat Med. 2012 Jul; 18(7): 1102–1111. doi: 10.1038/nm.2826

PMCID:: PMC3541027

Abstract Article PDF–1.8M

Select item 352936511.

Steroid Receptor Coactivator-1 Mediates Estrogenic Actions to Prevent Body Weight Gain in Female Mice

Liangru Zhu, Yongjie Yang, Pingwen Xu, Fang Zou, Xiaofeng Yan, Lan Liao, Jianming Xu, Bert W. O'Malley, Yong Xu

Endocrinology. 2013 Jan; 154(1): 150–158. Published online 2012 Dec 4. doi: 10.1210/en.2012-2007

PMCID:: PMC3529365

Abstract Article

Select item 295053312.

The Type I Interferon Signaling Pathway Is a Target for Glucocorticoid Inhibition

Jamie R. Flammer, Jana Dobrovolna, Megan A. Kennedy, Yurii Chinenov, Christopher K. Glass, Lionel B. Ivashkiv, Inez Rogatsky

Mol Cell Biol. 2010 Oct; 30(19): 4564–4574. Published online 2010 Aug 2. doi: 10.1128/MCB.00146-10

PMCID:: PMC2950533

Abstract Article PDF–1.6M

Select item 271787013.

In Vivo Interaction of Steroid Receptor Coactivator (SRC)-1 and the Activation Function-2 Domain of the Thyroid Hormone Receptor (TR) β in TRβ E457A Knock-In and SRC-1 Knockout mice

Manuela Alonso, Charles Goodwin, XiaoHui Liao, Tania Ortiga-Carvalho, Danielle S. Machado, Fredric E. Wondisford, Samuel Refetoff, Roy E. Weiss

Endocrinology. 2009 Aug; 150(8): 3927–3934. Published online 2009 Apr 30. doi: 10.1210/en.2009-0093

PMCID:: PMC2717870

Abstract Article

Select item 268308714.

Steroid receptor coactivator-1 is necessary for regulation of corticotropin-releasing hormone by chronic stress and glucocorticoids

Servane Lachize, Ede M. Apostolakis, Siem van der Laan, Ans M. I. Tijssen, Jianming Xu, E. Ronald de Kloet, Onno C. Meijer

Proc Natl Acad Sci U S A. 2009 May 12; 106(19): 8038–8042. Published online 2009 Apr 29. doi: 10.1073/pnas.0812062106

PMCID:: PMC2683087

Abstract Article PDF–510K

Select item 258712215.

Dissection of Genetic Mechanisms Governing the Expression of Serum Retroviral gp70 Implicated in Murine Lupus Nephritis

Lucie Baudino, Kumiko Yoshinobu, Naoki Morito, Shuichi Kikuchi, Liliane Fossati-Jimack, Bernard J. Morley, Timothy J. Vyse, Sachiko Hirose, Trine N. Jørgensen, Rebecca M. Tucker, Christina L. Roark, Brian L. Kotzin, Leonard H. Evans, Shozo Izui

J Immunol. Author manuscript; available in PMC 2009 Aug 15.

Published in final edited form as: J Immunol. 2008 Aug 15; 181(4): 2846–2854. doi: 10.4049/jimmunol.181.4.2846

PMCID:: PMC2587122

Abstract Article PDF–1.1M

Select item 183985616.

Crystal Structure of the PXR-T1317 Complex Provides a Scaffold to Examine the Potential for Receptor Antagonism

Yu Xue, Esther Chao, William J. Zuercher, Timothy M. Willson, Jon L. Collins, Matthew R. Redinbo

Bioorg Med Chem. Author manuscript; available in PMC 2008 Mar 1.

Published in final edited form as: Bioorg Med Chem. 2007 Mar 1; 15(5): 2156–2166. Published online 2006 Dec 20. doi: 10.1016/j.bmc.2006.12.026

PMCID:: PMC1839856

Abstract Article PDF–1.0M

Select item 123432217.

Dynamic Cell Type Specificity of SRC-1 Coactivator in Modulating Uterine Progesterone Receptor Function in Mice

Sang Jun Han, Jaewook Jeong, Francesco J. DeMayo, Jianming Xu, Sophia Y. Tsai, Ming-Jer Tsai, Bert W. O'Malley

Mol Cell Biol. 2005 Sep; 25(18): 8150–8165. doi: 10.1128/MCB.25.18.8150-8165.2005

PMCID:: PMC1234322

Abstract Article PDF–1.1M

Select item 122378218.

Dual action of oestrogens on the mouse constitutive androstane receptor.

Janne Mäkinen, Mika Reinisalo, Kaisa Niemi, Pirkko Viitala, Johanna Jyrkkärinne, Hinfan Chung, Olavi Pelkonen, Paavo Honkakoski

Biochem J. 2003 Dec 1; 376(Pt 2): 465–472. doi: 10.1042/BJ20030553

PMCID:: PMC1223782

Summary PDF–186K

Select item 38476819.

Partially redundant functions of SRC-1 and TIF2 in postnatal survival and male reproduction

Manuel Mark, Hiromi Yoshida-Komiya, Martine Gehin, Lan Liao, Ming-Jer Tsai, Bert W. O'Malley, Pierre Chambon, Jianming Xu

Proc Natl Acad Sci U S A. 2004 Mar 30; 101(13): 4453–4458. doi: 10.1073/pnas.0400234101

PMCID:: PMC384768

Abstract Article PDF–663K

Select item 756934920.

Interleukin-13 receptor subunit alpha-2 is a target of progesterone receptor and steroid receptor coactivator-1 in the mouse uterus

Ryan M Marquardt, Kevin Lee, Tae Hoon Kim, Brandon Lee, Francesco J DeMayo, Jae-Wook Jeong

Biol Reprod. 2020 Oct; 103(4): 760–768. Published online 2020 Jun 19. doi: 10.1093/biolre/ioaa110

PMCID:: PMC7569349

Abstract Article PDF–1.1M

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