PMC Links for Gene (Select 18176) - PMC

Links from Gene

Items: 1 to 20 of 137

<< First< Prev

Page of 7

Select item 104154031.

Neuroblastoma RAS viral oncogene homolog (N-RAS) deficiency aggravates liver injury and fibrosis

Kang Zheng, Fengjie Hao, Sandra Medrano-Garcia, Chaobo Chen, Feifei Guo, Laura Morán-Blanco, Sandra Rodríguez-Perales, Raúl Torres-Ruiz, María Isabel Peligros, Javier Vaquero, Rafael Bañares, Manuel Gómez del Moral, José R. Regueiro, Eduardo Martínez-Naves, Mohamed Ramadan Mohamed, Rocío Gallego-Durán, Douglas Maya, Javier Ampuero, Manuel Romero-Gómez, Albert Gilbert-Ramos, Sergi Guixé-Muntet, Anabel Fernández-Iglesias, Jordi Gracia-Sancho, Mar Coll, Isabel Graupera, Pere Ginès, Andreea Ciudin, Jesús Rivera-Esteban, Juan M. Pericàs, María Dolores Frutos, Bruno Ramos Molina, José María Herranz, Matías A. Ávila, Yulia A. Nevzorova, Edgar Fernández-Malavé, Francisco Javier Cubero

Cell Death Dis. 2023 Aug; 14(8): 514. Published online 2023 Aug 10. doi: 10.1038/s41419-023-06029-y

PMCID:: PMC10415403

Abstract Article PDF–5.4M

Select item 91741802.

Enhanced BRAF engagement by NRAS mutants capable of promoting melanoma initiation

Brandon M. Murphy, Elizabeth M. Terrell, Venkat R. Chirasani, Tirzah J. Weiss, Rachel E. Lew, Andrea M. Holderbaum, Aastha Dhakal, Valentina Posada, Marie Fort, Michael S. Bodnar, Leiah M. Carey, Min Chen, Craig J. Burd, Vincenzo Coppola, Deborah K. Morrison, Sharon L. Campbell, Christin E. Burd

Nat Commun. 2022; 13: 3153. Published online 2022 Jun 7. doi: 10.1038/s41467-022-30881-9

PMCID:: PMC9174180

Abstract Article PDF–2.7M

Select item 80359943.

Senescent bone marrow microenvironment promotes Nras-mutant leukemia

Peiqing Zhou, Chengxiang Xia, Tongjie Wang, Yong Dong, Qitong Weng, Xiaofei Liu, Yang Geng, Jinyong Wang, Juan Du

J Mol Cell Biol. 2021 Jan; 13(1): 72–74. Published online 2020 Nov 16. doi: 10.1093/jmcb/mjaa062

PMCID:: PMC8035994

Article PDF–534K

Select item 72256874.

Genetic disruption of N-Ras^G12D palmitoylation perturbs hematopoiesis and prevents myeloid transformation in mice

Noemi A. Zambetti, Ari J. Firestone, Jarrett R. Remsberg, Benjamin J. Huang, Jasmine C. Wong, Amanda M. Long, Marina Predovic, Radu M. Suciu, Anagha Inguva, Scott C. Kogan, Kevin M. Haigis, Benjamin F. Cravatt, Kevin Shannon

Blood. 2020 May 14; 135(20): 1772–1782. Prepublished online 2020 Mar 27. doi: 10.1182/blood.2019003530

PMCID:: PMC7225687

Abstract Article

Select item 67700725.

Synergy of NUP98-HOXA10 Fusion Gene and NrasG12D Mutation Preserves the Stemness of Hematopoietic Stem Cells on Culture Condition

Yong Dong, Chengxiang Xia, Qitong Weng, Tongjie Wang, Fangxiao Hu, Kaitao Wang, Xiaofei Liu, Yang Geng, Lijuan Liu, Hongling Wu, Juan Du

Cells. 2019 Sep; 8(9): 951. Published online 2019 Aug 22. doi: 10.3390/cells8090951

PMCID:: PMC6770072

Abstract Article PDF–3.0M

Select item 40385796.

Combined MEK and JAK inhibition abrogates murine myeloproliferative neoplasm

Guangyao Kong, Mark Wunderlich, David Yang, Erik A. Ranheim, Ken H. Young, Jinyong Wang, Yuan-I Chang, Juan Du, Yangang Liu, Sin Ruow Tey, Xinmin Zhang, Mark Juckett, Ryan Mattison, Alisa Damnernsawad, Jingfang Zhang, James C. Mulloy, Jing Zhang

J Clin Invest. 2014 Jun 2; 124(6): 2762–2773. Published online 2014 May 8. doi: 10.1172/JCI74182

PMCID:: PMC4038579

Abstract Article PDF–3.1M

Select item 37707497.

Dominant Role of Oncogene Dosage and Absence of Tumor Suppressor Activity in Nras-Driven Hematopoietic Transformation

Jin Xu, Kevin M. Haigis, Ari J. Firestone, Megan E. McNerney, Qing Li, Elizabeth Davis, Shann-Ching Chen, Joy Nakitandwe, James Downing, Tyler Jacks, Michelle M. Le Beau, Kevin Shannon

Cancer Discov. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: Cancer Discov. 2013 Sep; 3(9): 993–1001. Published online 2013 Jun 3. doi: 10.1158/2159-8290.CD-13-0096

PMCID:: PMC3770749

Abstract Article PDF–1.4M

Select item 36709288.

In TCR-Stimulated T-cells, N-ras Regulates Specific Genes and Signal Transduction Pathways

Stephen J. Lynch, Jiri Zavadil, Angel Pellicer

PLoS One. 2013; 8(6): e63193. Published online 2013 Jun 3. doi: 10.1371/journal.pone.0063193

Correction in:: PLoS One. 2013; 8(9): 10.1371/annotation/f0d2b6b0-7d87-492e-8505-5159c4b5bdd5.

PMCID:: PMC3670928

Abstract Article PDF–668K

Select item 35953979.

Mutant N-Ras protects colorectal cancer cells from stress-induced apoptosis and contributes to cancer development and progression

Yufang Wang, Sérgia Velho, Efsevia Vakiani, Shouyong Peng, Adam J. Bass, Gerald C. Chu, Jessica Gierut, James M. Bugni, Channing J. Der, Mark Philips, David B. Solit, Kevin M. Haigis

Cancer Discov. Author manuscript; available in PMC 2014 Mar 1.

Published in final edited form as: Cancer Discov. 2013 Mar; 3(3): 294–307. Published online 2012 Dec 28. doi: 10.1158/2159-8290.CD-12-0198

PMCID:: PMC3595397

Abstract Article PDF–2.7M

Select item 357215210.

Deregulated Nras Expression in Knock-In Animals Harboring a Gammaretroviral Long Terminal Repeat at the Nras/Csde1 Locus

Borja Ballarín-González, Louise Berkhoudt Lassen, Randi Jessen, Annette Füchtbauer, Ernst-Martin Füchtbauer, Finn Skou Pedersen

PLoS One. 2013; 8(2): e56029. Published online 2013 Feb 13. doi: 10.1371/journal.pone.0056029

PMCID:: PMC3572152

Abstract Article PDF–1003K

Select item 341091811.

Nras Overexpression Results in Granulocytosis, T-Cell Expansion and Early Lethality in Mice

Louise Berkhoudt Lassen, Borja Ballarín-González, Alexander Schmitz, Annette Füchtbauer, Finn Skou Pedersen, Ernst-Martin Füchtbauer

PLoS One. 2012; 7(8): e42216. Published online 2012 Aug 2. doi: 10.1371/journal.pone.0042216

PMCID:: PMC3410918

Abstract Article PDF–639K

Select item 321859612.

Distinct requirements of hematopoietic stem cell activity and Nras G12D signaling in different cell types during leukemogenesis

Jinyong Wang, Yangang Liu, Li Xuan Tan, Juinn Cherng Lo, Juan Du, Myung-Jeom Ryu, Erik A Ranheim, Jing Zhang

Cell Cycle. 2011 Sep 1; 10(17): 2836–2839. Published online 2011 Sep 1. doi: 10.4161/cc.10.17.17195

PMCID:: PMC3218596

Abstract Article PDF–3.6M

Select item 305664513.

Hematopoiesis and leukemogenesis in mice expressing oncogenic Nras^G12D from the endogenous locus

Qing Li, Kevin M. Haigis, Andrew McDaniel, Emily Harding-Theobald, Scott C. Kogan, Keiko Akagi, Jasmine C. Y. Wong, Benjamin S. Braun, Linda Wolff, Tyler Jacks, Kevin Shannon

Blood. 2011 Feb 10; 117(6): 2022–2032. Prepublished online 2010 Dec 16. doi: 10.1182/blood-2010-04-280750

PMCID:: PMC3056645

Abstract Article

Select item 303138614.

Endogenous oncogenic Nras mutation promotes aberrant GM-CSF signaling in granulocytic/monocytic precursors in a murine model of chronic myelomonocytic leukemia

Jinyong Wang, Yangang Liu, Zeyang Li, Juan Du, Myung-Jeom Ryu, Philip R. Taylor, Mark D. Fleming, Ken H. Young, Henry Pitot, Jing Zhang

Blood. 2010 Dec 23; 116(26): 5991–6002. Prepublished online 2010 Oct 4. doi: 10.1182/blood-2010-04-281527

PMCID:: PMC3031386

Abstract Article

Select item 286726815.

Palmitoylation of oncogenic NRAS is essential for leukemogenesis

Benjamin Cuiffo, Ruibao Ren

Blood. 2010 Apr 29; 115(17): 3598–3605. Prepublished online 2010 Mar 3. doi: 10.1182/blood-2009-03-213876

PMCID:: PMC2867268

Abstract Article

Select item 39376716.

Three human transforming genes are related to the viral ras oncogenes.

K Shimizu, M Goldfarb, Y Suard, M Perucho, Y Li, T Kamata, J Feramisco, E Stavnezer, J Fogh, M H Wigler

Proc Natl Acad Sci U S A. 1983 Apr; 80(8): 2112–2116. doi: 10.1073/pnas.80.8.2112

PMCID:: PMC393767

Summary Page Browse PDF–1.5M

Select item 13468717.

Cellular N-Ras Promotes Cell Survival by Downregulation of Jun N-Terminal Protein Kinase and p38

Janice C. Wolfman, Todd Palmby, Channing J. Der, Alan Wolfman

Mol Cell Biol. 2002 Mar; 22(5): 1589–1606. doi: 10.1128/mcb.22.5.1589-1606.2002

PMCID:: PMC134687

Abstract Article PDF–628K

Select item 4258918.

The murine N-ras gene is not essential for growth and development.

H Umanoff, W Edelmann, A Pellicer, R Kucherlapati

Proc Natl Acad Sci U S A. 1995 Feb 28; 92(5): 1709–1713. doi: 10.1073/pnas.92.5.1709

PMCID:: PMC42589

Summary Page Browse PDF–1.4M

Select item 1072114919.

A gain-of-function p53 mutant synergizes with oncogenic NRAS to promote acute myeloid leukemia in mice

Adhithi Rajagopalan, Yubin Feng, Meher B. Gayatri, Erik A. Ranheim, Taylor Klungness, Daniel R. Matson, Moon Hee Lee, Mabel Minji Jung, Yun Zhou, Xin Gao, Kalyan V.G. Nadiminti, David T. Yang, Vu L. Tran, Eric Padron, Shigeki Miyamoto, Emery H. Bresnick, Jing Zhang

J Clin Invest. 2023 Dec 15; 133(24): e173116. Published online 2023 Dec 15. doi: 10.1172/JCI173116

PMCID:: PMC10721149

Abstract Article PDF–6.6M

Select item 981072320.

Endogenous IL-1 receptor antagonist restricts healthy and malignant myeloproliferation

Alicia Villatoro, Vincent Cuminetti, Aurora Bernal, Carlos Torroja, Itziar Cossío, Alberto Benguría, Marc Ferré, Joanna Konieczny, Enrique Vázquez, Andrea Rubio, Peter Utnes, Almudena Tello, Xiaona You, Christopher G. Fenton, Ruth H. Paulssen, Jing Zhang, Fátima Sánchez-Cabo, Ana Dopazo, Anders Vik, Endre Anderssen, Andrés Hidalgo, Lorena Arranz

Nat Commun. 2023; 14: 12. Published online 2023 Jan 3. doi: 10.1038/s41467-022-35700-9

Correction in:: Nat Commun. 2023; 14: 3874.

PMCID:: PMC9810723

Abstract Article PDF–5.1M

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from Gene

Items: 1 to 20 of 137

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity