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Items: 1 to 20 of 106

1.
Exclusion of NUMB Exon12 Controls Cancer Cell Migration through Regulation of Notch1-SMAD3 Crosstalk
Zheng Zhan, Ningyang Yuan, Xue You, Kai Meng, Rula Sha, Zhenzhen Wang, Qian Peng, Zhiqin Xie, Ruijiao Chen, Ying Feng
Int J Mol Sci. 2022 Apr; 23(8): 4363. Published online 2022 Apr 14. doi: 10.3390/ijms23084363
PMCID:
PMC9027642
AbstractArticlePDF–3.6M
2.
Numb is required for optimal contraction of skeletal muscle
Rita De Gasperi, Chenglin Mo, Daniella Azulai, Zhiying Wang, Lauren M. Harlow, Yating Du, Zachary Graham, Jiangping Pan, Xin‐hua Liu, Lei Guo, Bin Zhang, Fred Ko, Ashleigh M. Raczkowski, William A. Bauman, Chris N. Goulbourne, Wei Zhao, Marco Brotto, Christopher P. Cardozo
J Cachexia Sarcopenia Muscle. 2022 Feb; 13(1): 454–466. Published online 2022 Jan 9. doi: 10.1002/jcsm.12907
PMCID:
PMC8818612
AbstractArticlePDF–24M
3.
Dynamic Regulation of Mammalian Numb by G Protein-coupled Receptors and Protein Kinase C Activation: Structural Determinants of Numb Association with the Cortical Membrane
Sascha E. Dho, JoAnn Trejo, David P. Siderovski, C. Jane McGlade
Mol Biol Cell. 2006 Sep; 17(9): 4142–4155. doi: 10.1091/mbc.E06-02-0097
PMCID:
PMC1593178
AbstractArticlePDF–4.7M
4.
NUMB as a Therapeutic Target for Melanoma
Denitsa M. Hristova, Takeshi Fukumoto, Chihiro Takemori, Le Gao, Xia Hua, Joshua X. Wang, Ling Li, Marilda Beqiri, Andrea Watters, Adina Vultur, Yusra Gimie, Vito Rebecca, Anastasia Samarkina, Haruki Jimbo, Chikako Nishigori, Jie Zhang, Chaoran Cheng, Zhi Wei, Rajasekharan Somasundaram, Mizuho Fukunaga-Kalabis, Meenhard Herlyn
J Invest Dermatol. Author manuscript; available in PMC 2022 Nov 28.
Published in final edited form as: J Invest Dermatol. 2022 Jul; 142(7): 1882–1892.e5. Published online 2021 Dec 7. doi: 10.1016/j.jid.2021.11.027
PMCID:
PMC9704357
AbstractArticlePDF–2.1M
5.
Numb Promotes Autophagy through p53 Pathway in Acute Kidney Injury Induced by Cisplatin
Ze Liu, Yong Li, Yongmei He, Junjie Wang
Anal Cell Pathol (Amst) 2022; 2022: 8213683. Published online 2022 Jun 27. doi: 10.1155/2022/8213683
PMCID:
PMC9252835
AbstractArticlePDF–2.3M
6.
MAD2B promotes podocyte injury through regulating Numb-dependent Notch 1 pathway in diabetic nephropathy
Meng-Ran Li, Chun-Tao Lei, Hui Tang, Xing-Jie Yin, Zhe Hao, Yang Qiu, Ya-Ru Xie, Jie-Yu Zeng, Hua Su, Chun Zhang
Int J Biol Sci. 2022; 18(5): 1896–1911. Published online 2022 Feb 21. doi: 10.7150/ijbs.68977
PMCID:
PMC8935242
AbstractArticlePDF–2.9M
7.
Numb and Numblike regulate sarcomere assembly and maintenance
Baolei Wang, Min Yang, Shujuan Li
J Clin Invest. 2022 Feb 1; 132(3): e139420. Published online 2022 Feb 1. doi: 10.1172/JCI139420
Correction in:
J Clin Invest. 2022 Jul 15; 132(14): e162883.
PMCID:
PMC8803338
AbstractArticlePDF–12M
8.
Loss of Numb promotes hepatic progenitor expansion and intrahepatic cholangiocarcinoma by enhancing Notch signaling
Yuke Shu, Qing Xu, Yahong Xu, Qing Tao, Mingyang Shao, Xiaoyue Cao, Yuwei Chen, Zhenru Wu, Menglin Chen, Yongjie Zhou, Ping Zhou, Yujun Shi, Hong Bu
Cell Death Dis. 2021 Nov; 12(11): 966. Published online 2021 Oct 19. doi: 10.1038/s41419-021-04263-w
PMCID:
PMC8526591
AbstractArticlePDF–7.8M
9.
Multifunctional protein 4.1R regulates the asymmetric segregation of Numb during terminal erythroid maturation
Shu-Ching Huang, Long V. Vu, Faye H. Yu, Dan T. Nguyen, Edward J. Benz, Jr.
J Biol Chem. 2021 Sep; 297(3): 101051. Published online 2021 Aug 6. doi: 10.1016/j.jbc.2021.101051
PMCID:
PMC8408529
AbstractArticlePDF–3.7M
10.
Depletion of Numb and Numblike in Murine Lung Epithelial Cells Ameliorates Bleomycin-Induced Lung Fibrosis by Inhibiting the β-Catenin Signaling Pathway
Alessandro Ianni, Michael Hofmann, Poonam Kumari, Shahriar Tarighi, Hamza M Al-Tamari, André Görgens, Bernd Giebel, Hendrik Nolte, Marcus Krüger, Isabelle Salwig, Soni Savai Pullamsetti, Andreas Günther, André Schneider, Thomas Braun
Front Cell Dev Biol. 2021; 9: 639162. Published online 2021 May 26. doi: 10.3389/fcell.2021.639162
PMCID:
PMC8187792
AbstractArticlePDF–9.4M
11.
EGFR Signaling Termination via Numb Trafficking in Ependymal Progenitors Controls Postnatal Neurogenic Niche Differentiation
Khadar Abdi, Gabriel Neves, Joon Pyun, Emre Kiziltug, Angelica Ahrens, Chay T. Kuo
Cell Rep. Author manuscript; available in PMC 2019 Sep 30.
Published in final edited form as: Cell Rep. 2019 Aug 20; 28(8): 2012–2022.e4. doi: 10.1016/j.celrep.2019.07.056
PMCID:
PMC6768562
AbstractArticlePDF–2.2M
12.
Plk1 phosphorylation of Numb leads to impaired DNA damage response
C Shao, S-J Chien, E Farah, Z Li, N Ahmad, X Liu
Oncogene. Author manuscript; available in PMC 2019 Feb 8.
Published in final edited form as: Oncogene. 2018 Feb 8; 37(6): 810–820. Published online 2017 Oct 23. doi: 10.1038/onc.2017.379
PMCID:
PMC5931337
AbstractArticlePDF–2.0M
13.
A Novel Role of Numb as A Regulator of Pro-inflammatory Cytokine Production in Macrophages in Response to Toll-like Receptor 4
Patipark Kueanjinda, Sittiruk Roytrakul, Tanapat Palaga
Sci Rep. 2015; 5: 12784. Published online 2015 Aug 5. doi: 10.1038/srep12784
Correction in:
Sci Rep. 2015; 5: 14585.
PMCID:
PMC4542673
AbstractArticlePDF–1.5M
14.
Numb-dependent integration of pre-TCR and p53 function in T-cell precursor development
N M Martin-Blanco, S Checquolo, F Del Gaudio, R Palermo, G Franciosa, L Di Marcotullio, A Gulino, M Canelles, I Screpanti
Cell Death Dis. 2014 Oct; 5(10): e1472. Published online 2014 Oct 16. doi: 10.1038/cddis.2014.438
PMCID:
PMC4237259
AbstractArticlePDF–3.5M
15.
Expression and Function of NUMB in Odontogenesis
Haitao Li, Amsaveni Ramachandran, Qi Gao, Sriram Ravindran, Yiqiang Song, Carla Evans, Anne George
Biomed Res Int. 2013; 2013: 182965. Published online 2013 Jun 6. doi: 10.1155/2013/182965
PMCID:
PMC3690219
AbstractArticlePDF–11M
16.
Musashi-1 Post-Transcriptionally Enhances Phosphotyrosine-Binding Domain-Containing m-Numb Protein Expression in Regenerating Gastric Mucosa
Tetsufumi Takahashi, Hidekazu Suzuki, Takao Imai, Shinsuke Shibata, Yoshiaki Tabuchi, Kanji Tsuchimoto, Hideyuki Okano, Toshifumi Hibi
PLoS One. 2013; 8(1): e53540. Published online 2013 Jan 4. doi: 10.1371/journal.pone.0053540
Expression of Concern in:
PLoS One. 2023; 18(1): e0278798.
PMCID:
PMC3537613
AbstractArticlePDF–1.3M
17.
Numb Regulates Post-endocytic Trafficking and Degradation of Notch1
Melanie A. McGill, Sascha E. Dho, Gerry Weinmaster, C. Jane McGlade
J Biol Chem. 2009 Sep 25; 284(39): 26427–26438. Published online 2009 Jun 30. doi: 10.1074/jbc.M109.014845
PMCID:
PMC2785331
AbstractArticlePDF–3.4M
18.
Analysis of partner of inscuteable (mPins) expression in the developing mouse eye
B. Raji, A. Dansault, V. Vieira, G. de la Houssaye, E. Lacassagne, A. Kobetz, L. Arbogast, J.L. Dufier, J.B. Blumer, M. Menasche, M. Abitbol
Mol Vis. 2008; 14: 2575–2596. Published online 2008 Dec 31.
PMCID:
PMC2613078
AbstractArticlePDF–11M
19.
Mammalian Numb protein antagonizes Notch by controlling postendocytic trafficking of the Notch ligand Delta-like 4
Ximing Shao, Zhihao Ding, Ming Zhao, Ke Liu, Haiyan Sun, Juntao Chen, Xianming Liu, Yuzhen Zhang, Yang Hong, Huashun Li, Hongchang Li
J Biol Chem. 2017 Dec 15; 292(50): 20628–20643. Published online 2017 Oct 17. doi: 10.1074/jbc.M117.800946
PMCID:
PMC5733598
AbstractArticlePDF–5.7M
20.
Numb deficiency in cerebellar Purkinje cells impairs synaptic expression of metabotropic glutamate receptor and motor coordination
Liang Zhou, Dong Yang, De-Juan Wang, Ya-Jun Xie, Jia-Huan Zhou, Lin Zhou, Hao Huang, Shuo Han, Chong-Yu Shao, Hua-Shun Li, J. Julius Zhu, Meng-Sheng Qiu, Chris I. De Zeeuw, Ying Shen
Proc Natl Acad Sci U S A. 2015 Dec 15; 112(50): 15474–15479. Published online 2015 Nov 30. doi: 10.1073/pnas.1512915112
PMCID:
PMC4687583
AbstractArticlePDF–1.2M

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