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Select item 90941241.

Translational development of a tumor junction opening technology

Jiho Kim, Chang Li, Hongjie Wang, Swarnendu Kaviraj, Sanjay Singh, Laxman Savergave, Arjun Raghuwanshi, Sucheol Gil, Audrey Germond, Audrey Baldessari, Bingmae Chen, Steve Roffler, Pascal Fender, Charles Drescher, Darrick Carter, André Lieber

Sci Rep. 2022; 12: 7753. Published online 2022 May 11. doi: 10.1038/s41598-022-11843-z

PMCID:: PMC9094124

Article PDF–2.0M

Select item 90936962.

Serum DSG2 as a potential biomarker for diagnosis of esophageal squamous cell carcinoma and esophagogastric junction adenocarcinoma

Yin-Qiao Liu, Ling-Yu Chu, Tian Yang, Biao Zhang, Zheng-Tan Zheng, Jian-Jun Xie, Yi-Wei Xu, Wang-Kai Fang

Biosci Rep. 2022 May 27; 42(5): BSR20212612. Published online 2022 May 6. doi: 10.1042/BSR20212612

PMCID:: PMC9093696

Article PDF–1.0M

Select item 86925583.

Desmoglein 2 (DSG2) Is A Receptor of Human Adenovirus Type 55 Causing Adult Severe Community-Acquired Pneumonia

Jing Zhang, Kui Ma, Xiangyu Wang, Yinbo Jiang, Shan Zhao, Junxian Ou, Wendong Lan, Wenyi Guan, Xiaowei Wu, Heping Zheng, Bin Yang, Chengsong Wan, Wei Zhao, Jianguo Wu, Qiwei Zhang

Virol Sin. 2021 Dec; 36(6): 1400–1410. Published online 2021 Jul 5. doi: 10.1007/s12250-021-00414-7

PMCID:: PMC8692558

Article PDF–2.5M

Select item 85718904.

Identification of Desmoglein-2 as a novel target of Helicobacter pylori HtrA in epithelial cells

Sabine Bernegger, Robert Vidmar, Marko Fonovic, Gernot Posselt, Boris Turk, Silja Wessler

Cell Commun Signal. 2021; 19: 108. Published online 2021 Nov 6. doi: 10.1186/s12964-021-00788-x

PMCID:: PMC8571890

Article PDF–1.8M

Select item 80388585.

Hemi- and Homozygous Loss-of-Function Mutations in DSG2 (Desmoglein-2) Cause Recessive Arrhythmogenic Cardiomyopathy with an Early Onset

Andreas Brodehl, Alexey Meshkov, Roman Myasnikov, Anna Kiseleva, Olga Kulikova, Bärbel Klauke, Evgeniia Sotnikova, Caroline Stanasiuk, Mikhail Divashuk, Greta Marie Pohl, Maria Kudryavtseva, Karin Klingel, Brenda Gerull, Anastasia Zharikova, Jan Gummert, Sergey Koretskiy, Stephan Schubert, Elena Mershina, Anna Gärtner, Polina Pilus, Kai Thorsten Laser, Valentin Sinitsyn, Sergey Boytsov, Oxana Drapkina, Hendrik Milting

Int J Mol Sci. 2021 Apr; 22(7): 3786. Published online 2021 Apr 6. doi: 10.3390/ijms22073786

PMCID:: PMC8038858

Article PDF–4.4M

Select item 77894046.

DSG2 expression is low in colon cancer and correlates with poor survival

Tingting Yang, Xuan Gu, Lizhou Jia, Jiaojiao Guo, Qi Tang, Jin Zhu, Wei Zhao, Zhenqing Feng

BMC Gastroenterol. 2021; 21: 7. Published online 2021 Jan 6. doi: 10.1186/s12876-020-01588-2

PMCID:: PMC7789404

Article PDF–1.4M

Select item 74966147.

Chimeric oncolytic Ad5/3 virus replicates and lyses ovarian cancer cells through desmoglein‐2 cell entry receptor

Lukasz Kuryk, Anne‐Sophie W. Møller

J Med Virol. 2020 Aug; 92(8): 1309–1315. Published online 2020 Feb 3. doi: 10.1002/jmv.25677

PMCID:: PMC7496614

Article PDF–973K

Select item 68768588.

Prevalence and Electronic Health Record-based Phenotype of Loss-of-function Genetic Variants in Arrhythmogenic Right Ventricular Cardiomyopathy-associated Genes

Eric D. Carruth, Wilson Young, Dominik Beer, Cynthia A. James, Hugh Calkins, Linyuan Jing, Sushravya Raghunath, Dustin N. Hartzel, Joseph B. Leader, H. Lester Kirchner, Diane T. Smelser, David J. Carey, Melissa A. Kelly, Amy C. Sturm, Amro Alsaid, Brandon K. Fornwalt, Christopher M. Haggerty

Circ Genom Precis Med. Author manuscript; available in PMC 2020 Nov 1.

Published in final edited form as: Circ Genom Precis Med. 2019 Nov; 12(11): e002579. Published online 2019 Oct 22. doi: 10.1161/CIRCGEN.119.002579

PMCID:: PMC6876858

Article PDF–305K

Select item 64145209.

CryoEM structure of adenovirus type 3 fibre with desmoglein 2 shows an unusual mode of receptor engagement

Emilie Vassal-Stermann, Gregory Effantin, Chloe Zubieta, Wim Burmeister, Frédéric Iseni, Hongjie Wang, André Lieber, Guy Schoehn, Pascal Fender

Nat Commun. 2019; 10: 1181. Published online 2019 Mar 12. doi: 10.1038/s41467-019-09220-y

PMCID:: PMC6414520

Article PDF–1.3M

Select item 611747310.

DSG2 Is a Functional Cell Surface Marker for Identification and Isolation of Human Pluripotent Stem Cells

Jongjin Park, Yeonsung Son, Na Geum Lee, Kyungmin Lee, Dong Gwang Lee, Jinhoi Song, Jaemin Lee, Seokho Kim, Min Ji Cho, Ju-Hong Jang, Jangwook Lee, Jong-Gil Park, Yeon-Gu Kim, Jang-Seong Kim, Jungwoon Lee, Yee Sook Cho, Young-Jun Park, Baek Soo Han, Kwang-Hee Bae, Seungmin Han, Byunghoon Kang, Seungjoo Haam, Sang-Hyun Lee, Sang Chul Lee, Jeong-Ki Min

Stem Cell Reports. 2018 Jul 10; 11(1): 115–127. Published online 2018 Jun 14. doi: 10.1016/j.stemcr.2018.05.009

PMCID:: PMC6117473

Article PDF–4.2M

Select item 597666311.

Mapping of Adenovirus of serotype 3 fibre interaction to desmoglein 2 revealed a novel ‘non-classical’ mechanism of viral receptor engagement

Emilie Vassal-Stermann, Manon Mottet, Corinne Ducournau, Frédéric Iseni, Charles Vragniau, Hongjie Wang, Chloe Zubieta, André Lieber, Pascal Fender

Sci Rep. 2018; 8: 8381. Published online 2018 May 30. doi: 10.1038/s41598-018-26871-x

PMCID:: PMC5976663

Article PDF–1.6M

Select item 556160412.

Case reports of two pedigrees with recessive arrhythmogenic right ventricular cardiomyopathy associated with homozygous Thr335Ala variant in DSG2

Sami Qadri, Olli Anttonen, Juho Viikilä, Eija H. Seppälä, Samuel Myllykangas, Tero-Pekka Alastalo, Miia Holmström, Tiina Heliö, Juha W. Koskenvuo

BMC Med Genet. 2017; 18: 86. Published online 2017 Aug 17. doi: 10.1186/s12881-017-0442-3

PMCID:: PMC5561604

Article PDF–753K

Select item 552483713.

Desmoglein 2 regulates the intestinal epithelial barrier via p38 mitogen-activated protein kinase

Hanna Ungewiß, Franziska Vielmuth, Shintaro T. Suzuki, Andreas Maiser, Hartmann Harz, Heinrich Leonhardt, Daniela Kugelmann, Nicolas Schlegel, Jens Waschke

Sci Rep. 2017; 7: 6329. Published online 2017 Jul 24. doi: 10.1038/s41598-017-06713-y

PMCID:: PMC5524837

Article PDF–4.2M

Select item 550371814.

Desmoglein 2 modulates extracellular vesicle release from squamous cell carcinoma keratinocytes

Andrew M. Overmiller, Jennifer A. Pierluissi, Peter J. Wermuth, Sami Sauma, Ubaldo Martinez-Outschoorn, Madalina Tuluc, Adam Luginbuhl, Joseph Curry, Larry A. Harshyne, James K. Wahl, III, Andrew P. South, Mỹ G. Mahoney

FASEB J. 2017 Aug; 31(8): 3412–3424. Published online 2017 Apr 24. doi: 10.1096/fj.201601138RR

PMCID:: PMC5503718

Article

Select item 521681215.

Desmoglein 2 promotes vasculogenic mimicry in melanoma and is associated with poor clinical outcome

Lih Yin Tan, Chris Mintoff, M. Zahied Johan, Brenton W. Ebert, Clare Fedele, You Fang Zhang, Pacman Szeto, Karen E. Sheppard, Grant A. McArthur, Erwin Foster-Smith, Andrew Ruszkiewicz, Michael P. Brown, Claudine S. Bonder, Mark Shackleton, Lisa M. Ebert

Oncotarget. 2016 Jul 19; 7(29): 46492–46508. Published online 2016 Jun 22. doi: 10.18632/oncotarget.10216

PMCID:: PMC5216812

Article PDF–9.2M

Select item 512275816.

Palmitoylation of Desmoglein 2 Is a Regulator of Assembly Dynamics and Protein Turnover

Brett J. Roberts, Robert A. Svoboda, Andrew M. Overmiller, Joshua D. Lewis, Andrew P. Kowalczyk, My G. Mahoney, Keith R. Johnson, James K. Wahl, III

J Biol Chem. 2016 Nov 25; 291(48): 24857–24865. Published online 2016 Oct 4. doi: 10.1074/jbc.M116.739458

PMCID:: PMC5122758

Article PDF–2.3M

Select item 462113617.

Intracellular Signaling and Desmoglein 2 Shedding Triggered by Human Adenoviruses Ad3, Ad14, and Ad14P1

Hongjie Wang, Corinne Ducournau, Kamola Saydaminova, Maximilian Richter, Roma Yumul, Martin Ho, Darrick Carter, Chloé Zubieta, Pascal Fender, André Lieber

J Virol. 2015 Nov 1; 89(21): 10841–10859. Published online 2015 Aug 19. doi: 10.1128/JVI.01425-15

PMCID:: PMC4621136

Article PDF–4.0M

Select item 456930918.

Inflammation-induced desmoglein-2 ectodomain shedding compromises the mucosal barrier

Ryuta Kamekura, Porfirio Nava, Mingli Feng, Miguel Quiros, Hikaru Nishio, Dominique A. Weber, Charles A. Parkos, Asma Nusrat

Mol Biol Cell. 2015 Sep 15; 26(18): 3165–3177. doi: 10.1091/mbc.E15-03-0147

PMCID:: PMC4569309

Article PDF–7.4M

Select item 441890419.

Cadherin flexibility provides a key difference between desmosomes and adherens junctions

Humera Tariq, Jordi Bella, Thomas A. Jowitt, David F. Holmes, Mansour Rouhi, Zhuxiang Nie, Clair Baldock, David Garrod, Lydia Tabernero

Proc Natl Acad Sci U S A. 2015 Apr 28; 112(17): 5395–5400. Published online 2015 Apr 8. doi: 10.1073/pnas.1420508112

PMCID:: PMC4418904

Article PDF–1.9M

Select item 404581120.

Characterization of Desmoglein Expression in the Normal Prostatic Gland. Desmoglein 2 Is an Independent Prognostic Factor for Aggressive Prostate Cancer

Alison G. Barber, Mireia Castillo-Martin, Dennis M. Bonal, Benjamin A. Rybicki, Angela M. Christiano, Carlos Cordon-Cardo

PLoS One. 2014; 9(6): e98786. Published online 2014 Jun 4. doi: 10.1371/journal.pone.0098786

PMCID:: PMC4045811

Article PDF–6.6M

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